Its story, however, extends deep into prehistory: the earliest Andean cultures depicted mescaline-containing cacti in their temples.   Mescaline was isolated in 1897 from the peyote cactus, first encountered by Europeans during the Spanish conquest of Mexico. During the twentieth century it was used by psychologists investigating the secrets of consciousness, spiritual seekers from Aleister Crowley to the president of the Church of Jesus Christ of Latter-day Saints, artists exploring the creative process, and psychiatrists looking to cure schizophrenia. Meanwhile peyote played a vital role in preserving and shaping Native American identity. Drawing on botany, pharmacology, ethnography, and the mind sciences and examining the mescaline experiences of figures from William James to Walter Benjamin to Hunter S. Thompson, this is an enthralling narrative of mescaline’s many lives.

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    Illustrations, notes, bibliography, index.

    Since then, this idea has been constantly propagated for the benefit of the international community. For many living in the vast country, however, the old Chinese adage holds true: “the mountains are high and the emperor is far away.” Few Westerners make it far beyond the major cities—the Chinese government has made it difficult to do so. David Eimer undertook a dangerous journey to China’s unexplored frontiers (it borders on fourteen other countries), to the outer reaches where Beijing's power has little influence. His chronicle shines new light on the world’s most populous nation, showing clearly that China remains in many ways a divided state. Traveling through the Islamic areas of Xinjiang province, into the forbidden zone of Tibet and across Route 219, which runs the rough boundary shared with India, the only disputed frontier in China, Eimer exposes the country’s inner conflict. All the tensions in China today—from its war against drugs and terrorism and the unstable relationships it maintains with Russia and Korea to its internal social issues—take on new meaning when seen from China’s most remote corners. A brilliant melding of journalism and history, The Emperor Far Away is essential reading for anyone interested in contemporary China.

    All animals, human or otherwise, thrive when they mimic key elements of life in their natural habitat. From diet to movement to sleep, this evolutionary perspective sheds light on some of our most pressing health concerns. What is causing the rise of chronic conditions, such as obesity, diabetes, and depression? Is eating red meat going to kill you? Is avoiding the sun actually the best way to avoid skin cancer? Durant takes readers on a thrilling ride to the Paleolithic and beyond, unlocking the health secrets of our ancient ancestors. What do obese gorillas teach us about weight loss? How can Paleolithic skulls contain beautiful sets of teeth? Why is the Bible so obsessed with hygiene? What do NASA astronauts teach us about getting a good night’s sleep? And how are Silicon Valley techies hacking the human body? Blending science and culture, anthropology and philosophy, John Durant distills the lessons from his adventures and shows how to apply them to day-to-day life, teaching people how to construct their own personal “habitat” that will enable them to thrive. The book doesn’t just address what we eat, but why we eat it; not just how to exercise, but the purpose of functional movement; not just being healthy, but leading a purposeful life. Combining the best of ancient wisdom with cutting edge science, Durant crafts a vision of health that is both fresh and futuristic.

    Indeed, from the time of the Ancient Greeks through the eras of Renaissance scientists and Enlightenment philosophers, the relationship between the notes of the musical scale was seen as a key to the very nature of the universe.In this engaging and accessible account, Stuart Isacoff leads us through the battles over that scale, placing them in the context of quarrels in the worlds of art, philosophy, religion, politics and science. The contentious adoption of the modern tuning system known as equal temperament called into question beliefs that had lasted nearly two millenia–and also made possible the music of Beethoven, Schubert, Chopin, Debussy, and all who followed. Filled with original insights, fascinating anecdotes, and portraits of some of the greatest geniuses of all time, Temperament is that rare book that will delight the novice and expert alike.

    Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Experiment: From 1946 to 1953, seventy-four boys are fed oatmeal laced with radioactive iron and calcium. Result: A better understanding of the effects of radioactivity on the human body. Experimental incidents such as these paved the way for crucial medical discoveries and lifesaving cures and procedures. But they also violated the rights of their subjects, many of whom did not give their consent to the experiments. The subjects suffered excruciating pain and humiliation. Some even died as a result of the procedures. Even in the twenty-first century—despite laws, regulations, and ethical conventions—the tension between medical experimentation and patient rights continues. How do doctors balance the need to test new medicines and procedures with their ethical and moral duty to protect the rights of human subjects? What price has been paid for medical knowledge? Can we learn from the broken oaths of the past? Take a harrowing journey through some of history's greatest medical advances—and its most horrifying medical atrocities. You'll read about orphans injected with lethal tuberculosis and concentration camp inmates tortured by Nazi doctors. You’ll also learn about radiation experimentation and present-day clinical trials that prove fatal. Through these stories, explore the human suffering that has gone hand in hand with medical advancement.

    But forensic analysis has been practiced for thousands of years. Ancient Chinese detectives studied dead bodies for signs of foul play, and in Victorian England, officials used crime scene photography and criminal profiling to investigate the Jack the Ripper murders. In the intervening decades, forensic science has evolved to use the most cutting-edge, innovative techniques and technologies. In this book, acclaimed author Bridget Heos uses real-life cases to tell the fascinating history of modern forensic science, from the first test for arsenic poisoning to fingerprinting, firearm and blood spatter analysis, DNA evidence, and all the important milestones in between. By turns captivating and shocking, Blood, Bullets, and Bones demonstrates the essential role forensic science has played in our criminal justice system.

    Either way, we can listen to nearly anything, at any time. The possibilities in this new age of listening overturn old assumptions about what it means to properly appreciate music—to be an “educated” listener. In Every Song Ever, the veteran New York Times music critic Ben Ratliff reimagines the very idea of music appreciation for our times. As familiar subdivisions like “rock” and “jazz” matter less and less and music’s accessible past becomes longer and broader, listeners can put aside the intentions of composers and musicians and engage music afresh, on their own terms. Ratliff isolates signal musical traits—such as repetition, speed, and virtuosity—and traces them across wildly diverse recordings to reveal unexpected connections. When we listen for slowness, for instance, we may detect surprising affinities between the drone metal of Sunn O))), the mixtape manipulations of DJ Screw, Sarah Vaughan singing “Lover Man,” and the final works of Shostakovich. And if we listen for closeness, we might notice how the tight harmonies of bluegrass vocals illuminate the virtuosic synchrony of John Coltrane’s quartet. Ratliff also goes in search of “the perfect moment”; considers what it means to hear emotion by sampling the complex sadness that powers the music of Nick Drake and Slayer; and examines the meaning of certain common behaviors, such as the impulse to document and possess the entire performance history of the Grateful Dead. Encompassing the sounds of five continents and several centuries, Ratliff’s book is an artful work of criticism and a lesson in open-mindedness. It is a definitive field guide to our radically altered musical habitat.

    In Oslo, actress Liv Ullmann read a long statement the activist had prepared for his 2009 trial. It read in part: I stand by the convictions I expressed in my June Second Hunger Strike Declaration twenty years ago I have no enemies and no hatred. None of the police who monitored, arrested, and interrogated me, none of the prosecutors who indicted me, and none of the judges who judged me are my enemies.That statement is one of the pieces in this book, which includes writings spanning two decades, providing insight into all aspects of Chinese life. These works not only chronicle a leading dissident s struggle against tyranny but enrich the record of universal longing for freedom and dignity. Liu speaks pragmatically, yet with deep-seated passion, about peasant land disputes, the Han Chinese in Tibet, child slavery, the CCP s Olympic strategy, the Internet in China, the contemporary craze for Confucius, and the Tiananmen massacre. Also presented are poems written for his wife, Liu Xia, public documents, and a foreword by Vaclav Havel.This collection is an aid to reflection for Western readers who might take for granted the values Liu has dedicated his life to achieving for his homeland.

    Few could or would have predicted that the improvised raps and raw beats busting out of New York City's urban underclass would one day become a multimillion-dollar business and one of music's most lucrative genres. Among those few were two visionaries: Russell Simmons, a young black man from Hollis, Queens, and Rick Rubin, a Jewish kid from Long Island. Though the two came from different backgrounds, their all-consuming passion for hip-hop brought them together. Soon they would revolutionize the music industry with their groundbreaking label, Def Jam Records. Def Jam, Inc. traces the company's incredible rise from the NYU dorm room of nineteen-year-old Rubin (where LL Cool J was discovered on a demo tape) to the powerhouse it is today; from financial struggles and scandals-including The Beastie Boys's departure from the label and Rubin's and Simmons's eventual parting-to revealing anecdotes about artists like Slick Rick, Public Enemy, Foxy Brown, Jay-Z, and DMX. Stacy Gueraseva, former editor in chief of Russell Simmons's magazine, Oneworld, had access to the biggest players on the scene, and brings you real conversations and a behind-the-scenes look from a decade-and a company-that turned the music world upside down. She takes you back to New York in the '80s, when late-night spots such as Danceteria and Nell's were burning with young, fresh rappers, and Simmons and Rubin had nothing but a hunch that they were on to something huge. Far more than just a biography of the two men who made it happen, Def Jam, Inc. is a journey into the world of rap itself. Both an intriguing business history as well as a gritty narrative, here is the definitive book on Def Jam-a must read for any fan of hip-hop as well as all popular-culture junkies.

    Professor Craig G. Benjamin of Grand Valley State University introduces you to the many people, achievements, and ideas that came out of Eastern civilization and played a role in creating the modern world.more info: http://www.thegreatcourses.com/tgc/co...

    Stone—host of Discovery Channel’s former series Most Evil—uses this common emotional reaction to horrifying acts as his starting point to explore the concept and reality of evil from a new perspective. In an in-depth discussion of the personality traits and behavior that constitute evil across a wide spectrum, Dr. Stone takes a clarifying scientific approach to a topic that for centuries has been inadequately explained by religious doctrines.Basing his analysis on the detailed biographies of more than 600 violent criminals, Stone has created a 22-level hierarchy of evil behavior, which loosely reflects the structure of Dante’s Inferno. He traces two salient personality traits that run the gamut from those who commit crimes of passion to perpetrators of the worst crimes—sadistic torture and murder. One trait is narcissism, as exhibited in people who are so self-centered that they have little or no ability to care about their victims. The other is aggression, the use of power over another person to inflict humiliation, suffering, and death.Stone then turns to the various factors that, singly or intertwined, contribute to pushing certain people over the edge into committing heinous crimes. They include heredity, adverse environments, violence-prone cultures, mental illness or brain injury, and abuse of mind-altering drugs. All are considered in the search for the root causes of evil behavior.What do psychology, psychiatry, and neuroscience tell us about the minds of those whose actions could be described as evil? And what will that mean for the rest of us? Stone discusses how an increased understanding of the causes of evil will affect the justice system. He predicts a day when certain persons can safely be declared salvageable and restored to society and when early signs of violence in children may be corrected before potentially dangerous patterns become entrenched.