He is known for both his breakthroughs in theoretical physics as well as his ability to make complex concepts accessible for all, and was beloved for his mischievous sense of humor. At the time of his death, Hawking was working on a final project: a book compiling his answers to the "big" questions that he was so often posed--questions that ranged beyond his academic field. Within these pages, he provides his personal views on our biggest challenges as a human race, and where we, as a planet, are heading next. Each section will be introduced by a leading thinker offering his or her own insight into Professor Hawking's contribution to our understanding.

    It seems so ordinary, everyone does it. Actually it's more of a black box, which Dehaene cracks open to reveal the awesome secrets within."--The New York Times Book Review An illuminating dive into the latest science on our brain's remarkable learning abilities and the potential of the machines we program to imitate themThe human brain is an extraordinary learning machine. Its ability to reprogram itself is unparalleled, and it remains the best source of inspiration for recent developments in artificial intelligence. But how do we learn? What innate biological foundations underlie our ability to acquire new information, and what principles modulate their efficiency?In How We Learn, Stanislas Dehaene finds the boundary of computer science, neurobiology, and cognitive psychology to explain how learning really works and how to make the best use of the brain's learning algorithms in our schools and universities, as well as in everyday life and at any age.

    More than a possibility, it is becoming a necessity: whether our hand is forced by climate change and resource depletion or whether future catastrophes compel us to abandon Earth, one day we will make our homes among the stars.World-renowned physicist and futurist Michio Kaku explores in rich, accessible detail how humanity might gradually develop a sustainable civilization in outer space. With his trademark storytelling verve, Kaku shows us how science fiction is becoming reality: mind-boggling developments in robotics, nanotechnology, and biotechnology could enable us to build habitable cities on Mars; nearby stars might be reached by microscopic spaceships sailing through space on laser beams; and technology might one day allow us to transcend our physical bodies entirely.With irrepressible enthusiasm and wonder, Dr. Kaku takes readers on a fascinating journey to a future in which humanity could finally fulfil its long-awaited destiny among the stars - and perhaps even achieve immortality.

    Four years in the writing, The Breakthrough is an "exciting read" about the discoveries which received the 2018 Nobel Prize winning discoveries in October, and a dramatic and exciting turning point in our relationship with a disease that has for too long defined us.For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold?As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses-tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it.In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step-harnessing the wealth of new information to create modern and more effective patient therapies-is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease.Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history

    As author Robert Greene explains, we are all a bit narcissistic, irrational, short-sighted and prone to compulsive and aggressive behavior. But once we accept and start to understand these aspects of human nature, we can begin to control and even benefit from them.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    A man who sees cartoon characters running across the room; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving.The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues. It’s the ultimate medical detective work. In this riveting book, one of the UK’s leading neurologists will take you with her as she follows the clues of her patients’ symptoms. It’s a journey that will open your eyes to the unfathomable intricacies of our brains, and the infinite variety of human capacity and experience.

    It’s time we stand face-to-digital-face with the true powers and limitations of the algorithms that already automate important decisions in healthcare, transportation, crime, and commerce. Hello World is indispensable preparation for the moral quandaries of a world run by code, and with the unfailingly entertaining Hannah Fry as our guide, we’ll be discussing these issues long after the last page is turned.

     In MATH WITH BAD DRAWINGS, Ben Orlin answers math's three big questions: Why do I need to learn this? When am I ever going to use it? Why is it so hard? The answers come in various forms-cartoons, drawings, jokes, and the stories and insights of an empathetic teacher who believes that math should belong to everyone.Eschewing the tired old curriculum that begins in the wading pool of addition and subtraction and progresses to the shark infested waters of calculus (AKA the Great Weed Out Course), Orlin instead shows us how to think like a mathematician by teaching us a new game of Tic-Tac-Toe, how to understand an economic crisis by rolling a pair of dice, and the mathematical reason why you should never buy a second lottery ticket. Every example in the book is illustrated with his trademark "bad drawings," which convey both his humor and his message with perfect pitch and clarity. Organized by unconventional but compelling topics such as "Statistics: The Fine Art of Honest Lying," "Design: The Geometry of Stuff That Works," and "Probability: The Mathematics of Maybe," MATH WITH BAD DRAWINGS is a perfect read for fans of illustrated popular science.

    Structured around a plane journey that sees encounters with substances from water and glue to coffee and wine, Liquid Rules shows how these liquids can bring death and destruction as well as wonder and fascination.From László Bíró's revolutionary pen and Abraham Gesner's kerosene to cutting-edge research on self-repairing roads and liquid computers, Miodownik uses his winning formula of scientific storytelling to bring the everyday to life. He reveals why liquids can flow up a tree but down a hill, why oil is sticky, how waves can travel so far, and how to make the perfect cup of tea. Here are the secret lives of substances.

    Our insatiable demand for animals -- for jewelry, pets, medicine, meat, trophies, and fur -- is driving a worldwide poaching epidemic, threatening the continued existence of countless species. Illegal wildlife trade now ranks among the largest contraband industries in the world, yet compared to drug, arms, or human trafficking, the wildlife crisis has received scant attention and support, leaving it up to passionate individuals fighting on the ground to try to ensure that elephants, tigers, rhinos, and more are still around for future generations. As Reefer Madness (Schlosser) took us into the drug market, or Susan Orlean descended into the swampy obsessions of TheOrchid Thief, Nuwer--an award-winning science journalist with a background in ecology--takes readers on a narrative journey to the front lines of the trade: to killing fields in Africa, traditional medicine black markets in China, and wild meat restaurants in Vietnam. Through exhaustive first-hand reporting that took her to ten countries, Nuwer explores the forces currently driving demand for animals and their parts; the toll that demand is extracting on species across the planet; and the conservationists, rangers, and activists who believe it is not too late to stop the impending extinctions. More than a depressing list of statistics, Poached is the story of the people who believe this is a battle that can be won, that our animals are not beyond salvation.

    In this collection of writings, the logbook of an intelligence always on the move, Carlo Rovelli follows his curiosity and invites us on a voyage through science, history, philosophy and politics.Written with his usual clarity and wit, these pieces range widely across time and space: from Newton's alchemy to Einstein's mistakes, from Nabokov's butterflies to Dante's cosmology, from travels in Africa to the consciousness of an octopus, from mind-altering psychedelic substances to the meaning of atheism.Charming, pithy and elegant, this book is the perfect gateway to the universe of one of the most influential scientists of our age.

    His assignment is to program the complex lunar landing phase in the Lunar Module's onboard computer. As he masters his art the reader learns about the computer, the mission, and a bit about spacecraft navigation and meets a cast of interesting characters along the way. As Apollo 11 approaches, the author flies lunar landings in simulators and meets the astronauts who will fly the LM for real. He explains the computer alarms that almost prevented Neil Armstrong from landing and describes a narrow escape from another dangerous problem. He helps Pete Conrad achieve a pinpoint landing on Apollo 12, and works with Apollo 16 commander John Young on a technique for landing even more precisely. On Apollo 14 he devises a workaround when a faulty pushbutton threatens Alan Shepard's mission, earning a NASA award, a story in Rolling Stone, and a few lines in the history books. Along the way the author hits the high points of his eclectic personal life, as he enters adulthood in the 1960s. He writes for students of the Apollo project, for whom the development of the flight software is still largely unexplored territory, but also for the young coders of the current digital culture, who will get the author's observations on the art of programming and who may identify as he explores sex, drugs, and the other excitements of the era. The underlying thesis is that the American space program in the 1960s was successful not in spite of, but in large measure because of the idealism, the freedom of thought, and the sense of exploration, inner and outer, that prevailed in the culture during that period. The memoir concludes in a party atmosphere at the spectacular night launch of Apollo 17 before a glittery crowd an occasion that marked the high water mark, so far, of human space exploration.

    In The Beautiful Cure, leading immunologist Professor Daniel Davis describes the scientific quest to understand how it works – and how it is affected by stress, sleep, age and our state of mind – and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being.The body's ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But within the last few years painstaking research has resulted in major advances in our understanding of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, it also plays a crucial role in our daily lives. Already we have found ways to harness these natural defences to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis and many age-related diseases, and we are starting to understand whether or not activities such as mindfulness might play a role in enhancing our physical resilience.Written by an expert at the forefront of this adventure, The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, of lives sacrificed and saved, introducing the reader to this revelatory new understanding of the human body and what it takes to be healthy.

    Guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world.We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture.Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits.

    “Things aren’t perfect by any means. But there are more scientists making more discoveries in more places about more things than ever before.” The twenty-six pieces assembled here chart the full spectrum of those discoveries. From the outer reaches of space, to the mysteries of the human mind, to the changing culture in labs and universities across the nation, we see time and again the sometimes rocky, sometimes revelatory road to understanding, and along the way catch a glimpse of all that’s left to learn.

    The passage of nine days, which is how long a drop of water typically stays in Earth's atmosphere, is something we can easily grasp. But spans of hundreds of years--the time a molecule of carbon dioxide resides in the atmosphere--approach the limits of our comprehension. Our everyday lives are shaped by processes that vastly predate us, and our habits will in turn have consequences that will outlast us by generations. Timefulness reveals how knowing the rhythms of Earth's deep past and conceiving of time as a geologist does can give us the perspective we need for a more sustainable future.Marcia Bjornerud shows how geologists chart the planet's past, explaining how we can determine the pace of solid Earth processes such as mountain building and erosion and comparing them with the more unstable rhythms of the oceans and atmosphere. These overlapping rates of change in the Earth system--some fast, some slow--demand a poly-temporal worldview, one that Bjornerud calls "timefulness." She explains why timefulness is vital in the Anthropocene, this human epoch of accelerating planetary change, and proposes sensible solutions for building a more time-literate society.This compelling book presents a new way of thinking about our place in time, enabling us to make decisions on multigenerational timescales. The lifespan of Earth may seem unfathomable compared to the brevity of human existence, but this view of time denies our deep roots in Earth's history--and the magnitude of our effects on the planet.

    But when Feynman said he didn’t understand quantum mechanics, he didn’t mean that he couldn’t do it – he meant that’s all he could do. He didn’t understand what the maths was saying: what quantum mechanics tells us about reality.Over the past decade or so, the enigma of quantum mechanics has come into sharper focus. We now realise that quantum mechanics is less about particles and waves, uncertainty and fuzziness, than a theory about information: about what can be known and how.This is more disturbing than our bad habit of describing the quantum world as ‘things behaving weirdly’ suggests. It calls into question the meanings and limits of space and time, cause and effect, and knowledge itself.The quantum world isn’t a different world: it is our world, and if anything deserves to be called ‘weird’, it’s us. This exhilarating book is about what quantum maths really means – and what it doesn’t mean.

    of Toronto and Google), Rodney Brooks (Rethink Robotics), Yann LeCun (Facebook) , Fei-Fei Li (Stanford and Google), Yoshua Bengio (Univ. of Montreal), Andrew Ng (AI Fund), Daphne Koller (Stanford), Stuart Russell (UC Berkeley), Nick Bostrom (Univ. of Oxford), Barbara Grosz (Harvard), David Ferrucci (Elemental Cognition), James Manyika (McKinsey), Judea Pearl (UCLA), Josh Tenenbaum (MIT), Rana el Kaliouby (Affectiva), Daniela Rus (MIT), Jeff Dean (Google), Cynthia Breazeal (MIT), Oren Etzioni (Allen Institute for AI), Gary Marcus (NYU), and Bryan Johnson (Kernel).Martin Ford is a prominent futurist, and author of Financial Times Business Book of the Year, Rise of the Robots. He speaks at conferences and companies around the world on what AI and automation might mean for the future. Editorial reviews: "In his newest book, Architects of Intelligence, Martin Ford provides us with an invaluable opportunity to learn from some of the most prominent thought leaders about the emerging fields of science that are shaping our future." -Al Gore, Former Vice President of the US "AI is going to shape our future, and Architects of Intelligence offers a unique and fascinating collection of perspectives from the top researchers and entrepreneurs who are driving progress in the field." - Eric Schmidt, former Chairman and CEO, Google "The best way to understand the challenges and consequences of AGI is to see inside the minds of industry experts shaping the field. Architects of Intelligence gives you that power." -Sam Altman, President of Y Combinator and co-chairman of OpenAI "Architects of Intelligence gets you inside the minds of the people building the technology that is going to transform our world. This is a book that everyone should read." -Reid Hoffman, Co-founder of LinkedIn

    Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her.In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.

    Whether pondering black holes or predicting discoveries at CERN, physicists believe the best theories are beautiful, natural, and elegant, and this standard separates popular theories from disposable ones. This is why, Sabine Hossenfelder argues, we have not seen a major breakthrough in the foundations of physics for more than four decades. The belief in beauty has become so dogmatic that it now conflicts with scientific objectivity: observation has been unable to confirm mindboggling theories, like supersymmetry or grand unification, invented by physicists based on aesthetic criteria. Worse, these "too good to not be true" theories are actually untestable and they have left the field in a cul-de-sac. To escape, physicists must rethink their methods. Only by embracing reality as it is can science discover the truth.

    She was the first woman to win a Nobel Prize, but her dedication to physics ultimately caused her death from radiation.From artists to aviators and scientists to revolutionaries, Little Guides to Great Lives is a brand new series of small-format guides introducing children to the most inspirational figures from history in a fun, accessible way. Launching with Leonardo da Vinci, Marie Curie, Nelson Mandela, and Amelia Earhart, Little Guides to Great Lives tells the stories of the most amazing people from all over the world and across history, with full-color illustrations and fresh design to bring their incredible stories to life.

      To date, we have discovered and described or named around 1.1 million insect species, with thousands of new ones being added every year. It is estimated that there are somewhere around five million insect species on Earth, making them the most diverse lineage of all life by far. This magnificent volume from the American Museum of Natural History tells their incredible story. Noted entomologist Michael S. Engel explores insects’ evolution and diversity; metamorphosis; pests, parasites, and plagues; society and language; camouflage; and pollination—as well as tales of discovery by intrepid entomologists. More than 180 illustrations from the American Museum of Natural History Research Library’s Rare Book Collection reveal the extraordinary world of insects down to their tiniest, most astonishing details, from butterflies’ iridescent wings to beetles’ vibrant colors.

    "The Broken Rules of Engagement" is not meant to be the ultimate voice on organizational behaviour but rather a contribution to available resources on how entities may reinforce and call in the "Special Forces" to aid their survival. The book entails and exposes corporate flaws and positives within: Organisations, Management, Trade Unions and what Employees are engaged in on a daily basis. The recent Economic and Social factors propelled me to produce this Manuscript. The book has many benefits and it's adaptable to any situation, regardless of the field of expertise be it Management or Employees level.The Book's Benefit: Entities would reap remarkable benefits and empower their Management teams and Employees on purchase of The Broken Rules of Engagement book. The book will also bring cohesion between Management and Employees and cultivate a happier workplace and increased productivity.GET YOURSELF A COPY! Be informed, fully developed and empowered to the point of readiness for you to attract great opportunities and unleash your full potential.Specific outcomes projected:1. Maximising Human Capital.2. Business continuity & Resiliency planning.3. Optimise and benefit from improved productivity.4. Increased Ethical sensitivity. 5. Sustained cost reduction. 6. Cost-focused lean enterprise.7. Lean Process design.

    Warren Andiman, an HIV/AIDS researcher who has been on the front lines battling infectious diseases for over forty years. In Animal Viruses and Humans: A Narrow Divide, Andiman traces the history of eight zoonotic viruses —deadly microbes that have made the leap directly from animals to human populations: Middle East Respiratory Syndrome (MERS), Swine influenza, Hantavirus, Monkeypox, Severe Acute Respiratory Syndrome (SARS), Rabies, Ebola, and Henipaviruses (Nipah and Hendra). He also illustrates the labor intensive and fascinating detective work that infectious disease specialists must do to uncover the source of an outbreak.Andiman also looks to the future, envisioning the effects on zoonoses (diseases caused by zoonotic viruses) of climate change, microenvironmental damage, population shifts, and globalization. He reveals the steps that we can, and must, take to stem the spread of animal viruses, explaining, “The zoonoses I've chosen to write about . . . are meant to describe only a small sample of what is already out there but, more menacingly, what is inevitably on its way, in forms we can only imagine.” Warren Andiman, MD is professor emeritus of pediatrics and epidemiology at the Yale Schools of Medicine and Public Health.

    Every massive star leaves behind a black hole when it dies, and every galaxy harbors a supermassive black hole at its center. Frighteningly enigmatic, these dark giants continue to astound even the scientists who spend their careers studying them. Which came first, the galaxy or its central black hole? What happens if you travel into one—instant death or something weirder? And, perhaps most important, how can we ever know anything for sure about black holes when they destroy information by their very nature?In Einstein’s Monsters, distinguished astronomer Chris Impey takes readers on an exploration of these and other questions at the cutting edge of astrophysics, as well as the history of black holes’ role in theoretical physics—from confirming Einstein’s equations for general relativity to testing string theory. He blends this history with a poignant account of the phenomena scientists have witnessed while observing black holes: stars swarming like bees around the center of our galaxy; black holes performing gravitational waltzes with visible stars; the cymbal clash of two black holes colliding, releasing ripples in space-time.Clear, compelling, and profound, Einstein’s Monsters reveals how our comprehension of black holes is intrinsically linked to how we make sense of the universe and our place within it. From the small questions to the big ones—from the tiniest particles to the nature of space-time itself—black holes might be the key to a deeper understanding of the cosmos.

    She explores how the seemingly benign practice of raising animals for milk is just one link in a chain that affects livestock across the agricultural spectrum. Gillespie takes readers to farms, auction yards, slaughterhouses, and even rendering plants to show how living cows become food. The result is an empathetic look at cows and our relationship with them, one that makes both their lives and their suffering real.

    In the seventy thousand years that modern human beings have walked this earth, we've come a long way. Art, science, culture, trade - on the evolutionary food chain, we're real winners. But, frankly, it's not exactly been plain sailing, and sometimes - just occasionally - we've managed to really, truly, quite unbelievably f*ck things up.From Chairman Mao's Four Pests Campaign, to the American Dustbowl; from the Austrian army attacking itself one drunken night, to the world's leading superpower electing a reality TV mogul as President... it's pretty safe to say that, as a species, we haven't exactly grown wiser with age. So, next time you think you've really f*cked up, this book will remind you: it could be so much worse

    Bringing together the best and most interesting science stories appearing in Quanta Magazine over the past five years, Alice and Bob Meet the Wall of Fire reports on some of the greatest scientific minds as they test the limits of human knowledge. Quanta, under editor-in-chief Thomas Lin, is the only popular publication that offers in-depth coverage of today's challenging, speculative, cutting-edge science. It communicates science by taking it seriously, wrestling with difficult concepts and clearly explaining them in a way that speaks to our innate curiosity about our world and ourselves.In the title story, Alice and Bob--beloved characters of various thought experiments in physics--grapple with gravitational forces, possible spaghettification, and a massive wall of fire as Alice jumps into a black hole. Another story considers whether the universe is impossible, in light of experimental results at the Large Hadron Collider. We learn about quantum reality and the mystery of quantum entanglement; explore the source of time's arrow; and witness a eureka moment when a quantum physicist exclaims: "Finally, we can understand why a cup of coffee equilibrates in a room." We reflect on humans' enormous skulls and the Brain Boom; consider the evolutionary benefits of loneliness; peel back the layers of the newest artificial-intelligence algorithms; follow the "battle for the heart and soul of physics"; and mourn the disappearance of the "diphoton bump," revealed to be a statistical fluctuation rather than a revolutionary new particle. These stories from Quanta give us a front-row seat to scientific discovery.ContributorsPhilip Ball, K. C. Cole, Robbert Dijkgraaf, Dan Falk, Courtney Humphries, Ferris Jabr, Katia Moskvitch, George Musser, Michael Nielsen, Jennifer Ouellette, John Pavlus, Emily Singer, Andreas von Bubnoff, Frank Wilczek, Natalie Wolchover, Carl Zimmer

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Animals move with astounding grace, speed, and versatility: how do they do it, and what can we learn from them? In How to Walk on Water and Climb up Walls, David Hu takes readers on an accessible, wondrous journey into the world of animal motion. From basement labs at MIT to the rain forests of Panama, Hu shows how animals have adapted and evolved to traverse their environments, taking advantage of physical laws with results that are startling and ingenious. In turn, the latest discoveries about animal mechanics are inspiring scientists to invent robots and devices that move with similar elegance and efficiency.Hu follows scientists as they investigate a multitude of animal movements, from the undulations of sandfish and the way that dogs shake off water in fractions of a second to the seemingly crash-resistant characteristics of insect flight. Not limiting his exploration to individual organisms, Hu describes the ways animals enact swarm intelligence, such as when army ants cooperate and link their bodies to create bridges that span ravines. He also looks at what scientists learn from nature's unexpected feats--such as snakes that fly, mosquitoes that survive rainstorms, and dead fish that swim upstream. As researchers better understand such issues as energy, flexibility, and water repellency in animal movement, they are applying this knowledge to the development of cutting-edge technology.Integrating biology, engineering, physics, and robotics, How to Walk on Water and Climb up Walls demystifies the remarkable mechanics behind animal locomotion.

    Meet a glowing squid, traveling fungus spores, and much more. The Bacteria Book walks the line between ew, gross! and oh, cool!, exploring why we need bacteria and introducing readers to its microbial mates--viruses, fungi, algae, archaea, and protozoa.The Bacteria Book is a fun and informative introduction to a STEM subject that brings kids up-close to the big world of tiny science. With remarkable photography, kooky character illustrations, and lots of fun facts, this book uses real-life examples of microbiology in action to show how tiny microbes affect us in big ways.

    But gravitational waves – ripples in the fabric of space and time – are unrelenting, passing through barriers that stop light dead.At the two 4-kilometre long LIGO observatories in the US, scientists developed incredibly sensitive detectors, capable of spotting a movement 100 times smaller than the nucleus of an atom. In 2015 they spotted the ripples produced by two black holes spiralling into each other, setting spacetime quivering.This was the first time black holes had ever been directly detected – and it promises far more for the future of astronomy. Brian Clegg presents a compelling story of human technical endeavour and a new, powerful path to understand the workings of the universe.Brian Clegg’s most recent books are The Reality Frame (Icon, 2017), What Colour is the Sun? (Icon, 2016) and Ten Billion Tomorrows (St Martin’s Press, 2016). His Dice World and A Brief History of Infinity were both longlisted for the Royal Society Prize for Science Books. He has also written Big Data for the Hot Science series. Brian has written for numerous publications including The Wall Street Journal, Nature, BBC Focus, Physics World, The Times and The Observer. Brian is editor of popularscience.co.uk and blogs at brianclegg.blogspot.com.

    This shy, snuffling, enigmatic animal has captured the imagination of children and adults for centuries – from Beatrix Potter’s Mrs Tiggywinkle to Sonic the Hedgehog.Full to the brim with fascinating insights and countryside lore, The Hedgehog Handbook explores different facets of this much-admired mammal – from its wildlife habits to its literary heritage, how different cultures have viewed the hedgehog and what we can do to help preserve this icon of rural life. Fun, sweet and warm hearted, The Hedgehog Handbook is a month by month celebration of one of the countryside’s best-loved creatures. Packed with inspirational quotes, entertaining facts, folklore and literary references, it’s the perfect gift for anyone with a penchant for prickles.

    Still remember when I started I had no clue on what was I supposed to do, little less was I aware of the challenges I would be facing and as a consequence I made all sort of mistakes that pushed me to limit of thinking is this was actually the path I should follow. Luckily for me, I was able to overcome all those issues and became a successful freelancer. I don't want you to suffer as much as I did and that's the reason why I have created this book, so that you are aware of the problems you'll most likely be facing and put action plans in place to prevent them or correct them. Also, this will give you a glimpse on what it takes to be a freelancer so that you can make an informed decision on whether this is the correct path for you or not. These are The 10 Things I Wish I Knew Before I Started Freelancing.

    From his five-year voyage across the high seas to 20 years of research, follow Darwin on his adventure to prove a theory that would change the world.Little Guides to Great Lives is a brand new series of small-format guides introducing children to the most inspirational figures from history in a fun, accessible way. From Curie to Kahlo and Darwin to Da Vinci, Little Guides to Great Lives tells the stories of the most amazing people from all over the world and across history, with colorful illustrations and fresh design to bring their incredible stories to life.

    Tells the thrilling tale of how each woman contributed, the struggles and resistance each experienced, and the amazing results. Consultants currently works for NASA.

    In an entertaining and engaging narrative, this popular science book gives readers the basic tools to understand how fusion works, its potential, and contemporary research problems.Written by two young researchers in the field, The Future of Fusion Energy explains how physical laws and the Earth's energy resources motivate the current fusion program — a program that is approaching a critical point. The world's largest science project and biggest ever fusion reactor, ITER, is nearing completion. Its success could trigger a worldwide race to build a power plant, but failure could delay fusion by decades. To these ends, this book details how ITER's results could be used to design an economically competitive power plant as well as some of the many alternative fusion concepts.Contents: Motivation: The Hydrogen-Powered Civilization Energy in Numbers and Graphs The Basics: Fundamentals of Fusion Energy Plasma Confinement Fusion Technology The State of the Art: The Past: Fusion Breakthroughs The Present: ITER The Future: Designing a Tokamak Power Plant Special Topics: Alternative Approaches to Fusion Energy Fusion and Nuclear Proliferation Fusion and Space Exploration Conclusions: When Will We Have Fusion? Readership: Motivated laypeople with an interest in fusion.

    But how do all these things work? In this book, Sean Gerrish offers an engaging and accessible overview of the breakthroughs in artificial intelligence and machine learning that have made today's machines so smart.Gerrish outlines some of the key ideas that enable intelligent machines to perceive and interact with the world. He describes the software architecture that allows self-driving cars to stay on the road and to navigate crowded urban environments; the million-dollar Netflix competition for a better recommendation engine (which had an unexpected ending); and how programmers trained computers to perform certain behaviors by offering them treats, as if they were training a dog. He explains how artificial neural networks enable computers to perceive the world—and to play Atari video games better than humans. He explains Watson's famous victory on Jeopardy, and he looks at how computers play games, describing AlphaGo and Deep Blue, which beat reigning world champions at the strategy games of Go and chess. Computers have not yet mastered everything, however; Gerrish outlines the difficulties in creating intelligent agents that can successfully play video games like StarCraft that have evaded solution—at least for now.Gerrish weaves the stories behind these breakthroughs into the narrative, introducing readers to many of the researchers involved, and keeping technical details to a minimum. Science and technology buffs will find this book an essential guide to a future in which machines can outsmart people.

    Somewhere in nature, a killer virus is boiling up in the bloodstream of a bird, bat, monkey, or pig, preparing to jump to a human being. This not-yet-detected germ has the potential to wipe out millions of lives over a matter of weeks or months. That risk makes the threat posed by ISIS, a ground war, a massive climate event, or even the dropping of a nuclear bomb on a major city pale in comparison.In The End of Epidemics, Duke Global Health Institute faculty member and past Chair of the Global Health Council Dr. Jonathan D. Quick examines the eradication of smallpox and devastating effects of influenza, AIDS, SARS, Ebola, and other viral diseases . Analyzing local and global efforts to contain these diseases and citing firsthand accounts of failure and success, Dr. Quick proposes a new set of actions which he has coined "The Power of Seven," to end epidemics before they can begin. These actions include:- Spend prudently to prevent disease before an epidemic strikes, rather than spending too little, too late- Ensure prompt, open, and accurate communication between nations and aid agencies, instead of secrecy and territorial disputes- Fight disease and prevent panic with innovation and good sciencePractical and urgent, The End of Epidemics is crucial reading for citizens, health professionals, and policy makers alike.

    That's 102 Lego(R) bricks for every person in the world. That's nothing however to the estimated seven billion billion billion atoms that make up each of us, let alone the between ten quadrillion vigintillion and one-hundred thousand quadrillion vigintillion atoms in the known observable universe.Thankfully, understanding atomic and subatomic physics need not be infathomable. Lego(R) bricks are a great way to visualize the blueprint of the Universe, right down to its smallest elements.Particle Physics Brick by Brick explains how and with what the universe came to be. It introduces the Standard Model of Physics, the "rule book" of physics which has been proven correct again and again since its mid-20 century development. Today, it is the gaps in the model that keep physicists busy.In concise chapters, the book assigns to each atomic element a colored Lego(R) brick, such as neutrons, leptons, and quarks. By assembling actual or imaginary bricks and observing their relationships and interactions, particle physics becomes clear. The book opens with the Standard Model of Physics, the physicists and the discoveries made over history, and directions on how to use the book.The chapters that follow are:Building Blocks and Construction Rules Building a Universe Electromagnetism and QED (Quantum ElectroDynamics) The Strong Force and QCD (Quantum ChromoDynamics) The Weak Force and Breaking Symmetries Broken Symmetry and Mass Problems with Ghosts Violated Symmetry The Future. Particle Physics Brick by Brick is a succinct introduction for anyone that wants to gain a basic understanding of the atomic world, its elements and how they interact. By using tangible substitutes -- bricks -- it brings the unseen atomic world into the realm of the visual.

    Each movie in Films from the Future provides the starting point for exploring potentially life-changing technologies and trends, from genetic engineering (Jurassic Park) and brain-enhancing drugs (Limitless), to human augmentation (Ghost in the Shell), and artificial intelligence (Ex Machina). These are woven together with emerging ideas on technological convergence and responsible and ethical innovation to provide a sweeping perspective on where our technologies are taking us, and how we ensure this is where we want to go.With each examination, you will take a progressive journey through the fascinating worlds of biological and genetic manipulation, human enhancement and cyber technologies, and nanotechnology. Maynard shows that the fantastical worlds of the movies might not be as impossible as we think. With a focus on hard science, economics, the social implications of technological feats, and the movies that could very well become our real-life future, Films from the Future will be sure to educate and entertain!

    Drawing insights from clinical workers, data collectors, organizational experts, and public health researchers, Pardis Sabeti and Lara Salahi expose a fractured system that failed to gather and share knowledge of the virus and ensure timely containment. The authors describe how much more could have been done by global medical and political organizations to safeguard the well-being of caregivers, patients, and communities affected by this devastating outbreak and they outline changes that are urgently needed to ensure a more effective coordinated response to the next epidemic.Secrecy, competition, and poor coordination plague nearly every major public health crisis--and we are seeing their deadly consequences play out again. A work of fearless integrity and unassailable authority, Outbreak Culture seeks to change the culture of responders.

    Heath in the 1950s and '60s has been described as among the most controversial experiments in US history. His work was alleged at the time to be part of MKUltra, the CIA's notorious "mind control" project. His research subjects included incarcerated convicts and gay men who wished to be "cured" of their sexual preference. Yet his cutting-edge research and legacy were quickly buried deep in Tulane University's archives. Investigative science journalist Lone Frank now tells the complete sage of this passionate, determined doctor and his groundbreaking neuroscience.More than fifty years after Heath's experiments, this very same treatment is becoming mainstream practice in modern psychiatry for everything from schizophrenia, anorexia, and compulsive behavior to depression, Parkinson's, and even substance addiction.Lone Frank uncovered lost documents and accounts of Heath's trailblazing work. She tracked down surviving colleagues and patients, and she delved into the current support for deep brain stimulation by scientists and patients alike. What has changed? Why do we today unquestioningly embrace this technology as a cure? How do we decide what is a disease of the brain to be cured and what should be allowed to remain unprobed and unprodded? And how do we weigh the decades of criticism against the promise of treatment that could be offered to millions of patients?Elegantly written and deeply fascinating, The Pleasure Shock weaves together biography, scientific history, and medical ethics. It is an adventure into our ever-shifting views of the mind and the fateful power we wield when we tinker with the self.

    In thirty-two concise and engrossing essays, the author provides a deeper understanding of the nature of the universe and those who strive to uncover its mysteries.   Bartusiak shares the back stories for many momentous astronomical discoveries, including the contributions of such pioneers as Beatrice Tinsley, with her groundbreaking research in galactic evolution, and Jocelyn Bell Burnell, the scientist who first discovered radio pulsars. An endlessly fascinating collection that you can dip into in any order, these pieces will transport you to ancient Mars, when water flowed freely across its surface; to the collision of two black holes, a cosmological event that released fifty times more energy than was radiating from every star in the universe; and to the beginning of time itself.

    These sophisticated time machines record growth, diet, and evolutionary history as clearly as tree rings map a redwood's lifespan. Each day of childhood is etched into tooth crowns and roots—capturing birth, nursing history, environmental clues, and illnesses. The study of ancient, fossilized teeth sheds light on how our ancestors grew up, how we evolved, and how prehistoric cultural transitions continue to affect humans today. In The Tales Teeth Tell, biological anthropologist Tanya Smith offers an engaging and surprising look at what teeth tell us about the evolution of primates—including our own uniqueness.Humans' impressive set of varied teeth provides a multipurpose toolkit honed by the diet choices of our mammalian ancestors. Fossil teeth, highly resilient because of their substantial mineral content, are all that is left of some long-extinct species. Smith explains how researchers employ painstaking techniques to coax microscopic secrets from these enigmatic remains. Counting tiny daily lines provides a way to estimate age that is more powerful than any other forensic technique. Dental plaque—so carefully removed by dental hygienists today—records our ancestors' behavior and health in the form of fossilized food particles and bacteria, including their DNA. Smith also traces the grisly origins of dentistry, reveals that the urge to pick one's teeth is not unique to humans, and illuminates the age-old pursuit of “dental art.” The book is generously illustrated with original photographs, many in color.

    Why does this tiny insect merit such intense scrutiny?Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases.Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.

    They are tales of quantum physics and general relativity, stars and black holes, dark matter and dark energy. Let yourself be swept away on a journey of discovery towards a deeper understanding of the cosmos.

    This insider's perspective examines incredible missions of robotic spacecraft to every corner of our solar system and beyond. Some were flown into glory, while others were planned and relegated to dusty filing cabinets. All were remarkable in their aspirations.Award-winning science writer Rod Pyle profiles both the remarkable spacecraft and the amazing scientists and engineers who made them possible. From the earliest sprints past Venus and Mars to Voyager1's current explorations of the space between the stars, this exciting book sheds new light on ever-more ambitious journeys designed to increase the human reach into the solar system. Drawing on his perspective as a writer for NASA's Jet Propulsion Laboratory, ground zero for NASA's planetary exploration, the author further details plans now in development to look for signs of life on Jupiter's moon Europa, submarines that will dive into the hazy hydrocarbon lakes of Saturn's moon Titan, and intelligent spacecraft that will operate for months without human intervention on Mars and in the outer solar system well into the 2030s. Equally compelling are programs of exploration that were considered but never left the drawing board, such as automobile-sized biology laboratories designed for a Mars landing in the 1960s and plans to detonate atomic bombs on the moon.Complemented by many rarely-seen photos and illustrations, these stories of incredible engineering achievements, daring imaginations, and technological genius will fascinate and inspire.

      Since the original edition of The Space Book was published in 2013, much has happened in the world of space exploration. This revised and updated edition, with a new introduction from author Jim Bell, brings the popular Milestones book up to date. It includes the most exciting and newsworthy breakthroughs, from the groundbreaking discovery of the Trappist-1 system to the technologies of the future. Take a full-color, chronological tour of the cosmos through completely new entries and spectacular images that cover developments in radio astronomy, NASA’s mission to Jupiter, the new Earth-like exoplanets, the world’s first interstellar solar sail mission, and more. Many existing entries have been updated with the results of completed and current missions, as well as illuminating recent photography.

    

    But Darwin published his Origin of Species nearly thirty years after his voyages and most of his labours in that time were focused on experimenting with and observing plants at his house in Kent. He was particularly interested in carnivorous and climbing plants, and in pollination and the evolution of flowers.Ken Thompson sees Darwin as a brilliant and revolutionary botanist, whose observations and theories were far ahead of his time - and are often only now being confirmed and extended by high-tech modern research. Like Darwin, he is fascinated and amazed by the powers of plants - particularly their Triffid-like aspects of movement, hunting and 'plant intelligence'.This is a much needed book that re-establishes Darwin as a pioneering botanist, whose close observations of plants were crucial to his theories of evolution.

    The presumed emptiness of coma or dementia scares us so much that we even sign living wills to avoid these states. Yet as Zen masters have long known, inner emptiness can also be productive and useful. We can reach this state through meditation, concentration, music, or even during sex. In fact, our brain loves emptiness — it makes us happy. Leading brain researcher Niels Birbaumer investigates the pleasure in emptiness and how we can take advantage of it. He explains how to overcome the evolutionary attentiveness of your brain and take a break from thinking — a skill that’s more important than ever in an increasingly frantic world.

    Fallout is an eye-opening odyssey through the first eight decades of this struggle and the radioactive landscapes it has left behind. We are, he finds, forever torn between technological hubris and all-too-human terror about what we have created.At first, Pearce reminds us, America loved the bomb. Las Vegas, only seventy miles from the Nevada site of some hundred atmospheric tests, crowned four Miss Atomic Bombs in 1950s. Later, communities downwind of these tests suffered high cancer rates. The fate of a group of Japanese fishermen, who suffered high radiation doses from the first hydrogen bomb test in Bikini atoll, was worse. The United States Atomic Energy Commission accused them of being Red spies and ignored requests from the doctors desperately trying to treat them.Pearce moves on to explore the closed cities of the Soviet Union, where plutonium was refined and nuclear bombs tested throughout the '50s and '60s, and where the full extent of environmental and human damage is only now coming to light. Exploring the radioactive badlands created by nuclear accidents--not only the well-known examples of Chernobyl and Fukushima, but also the little known area around Satlykovo in the Russian Ural Mountains and the Windscale fire in the UK--Pearce describes the compulsive secrecy, deviousness, and lack of accountability that have persisted even as the technology has morphed from military to civilian uses.Finally, Pearce turns to the toxic legacies of nuclear technology: the emerging dilemmas over handling its waste and decommissioning of the great radioactive structures of the nuclear age, and the fearful doublethink over the world's growing stockpiles of plutonium, the most lethal and ubiquitous product of nuclear technologies.For any reader who craves a clear-headed examination of the tangled relationship between a powerful technology and human politics, foibles, fears, and arrogance, Fallout is the definitive look at humanity's nuclear adventure.

    The Wake of the Whale presents the art, history, and challenge of whaling in the Caribbean and North Atlantic, based on a decade of award-winning fieldwork.Sightings of pilot whales in the frigid Nordic waters have drawn residents of the Faroe Islands to their boats and beaches for nearly a thousand years. Down in the tropics, around the islands of St. Vincent and the Grenadines, artisanal whaling is a younger trade, shaped by the legacies of slavery and colonialism but no less important to the local population. Each culture, Russell Fielding shows, has developed a distinct approach to whaling that preserves key traditions while adapting to threats of scarcity, the requirements of regulation, and a growing awareness of the humane treatment of animals.Yet these strategies struggle to account for the risks of regularly eating meat contaminated with methylmercury and other environmental pollutants introduced from abroad. Fielding considers how these and other factors may change whaling cultures forever, perhaps even bringing an end to this way of life.A rare mix of scientific and social insight, The Wake of the Whale raises compelling questions about the place of cultural traditions in the contemporary world and the sacrifices we must make for sustainability.Publication of this book was supported, in part, by a grant from Furthermore: a program of the J. M. Kaplan Fund.

    Dietrich explore these questions through the lives of eighteen exemplary biologists who had grand and often radical ideas that went far beyond the run-of-the-mill science of their peers.   From the Frenchman Jean-Baptiste Lamarck, who coined the word “biology” in the early nineteenth century, to the American James Lovelock, for whom the Earth is a living, breathing organism, these dreamers innovated in ways that forced their contemporaries to reexamine comfortable truths. With this collection readers will follow Jane Goodall into the hidden world of apes in African jungles and Francis Crick as he attacks the problem of consciousness. Join Mary Lasker on her campaign to conquer cancer and follow geneticist George Church as he dreams of bringing back woolly mammoths and Neanderthals. In these lives and the many others featured in these pages, we discover visions that were sometimes fantastical, quixotic, and even threatening and destabilizing, but always a challenge to the status quo.

    In industries ranging from food to tech to healthcare, customers want high-quality products and personalized experiences rather than one-size-fits-all solutions. Technology will be the ultimate enabler for companies to connect with people. To stay afloat in this rapidly shifting economic landscape, businesses need to ride the wave of Localmotion.In this indispensable guide, Alex Barseghian, a leader in connecting companies to their customers, gives an insider