As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Reconciliation: Islam, Democracy, and the West

    Taught to play the piano by her mother, she developed quickly into a prodigy, immersing herself in the work of classical masters like Bach and Brahms. She was just ten years old when she began a rigorous course of study at the Beijing Conservatory, laying the groundwork for what was sure to be an extraordinary career. But in 1966, when Xiao-Mei was seventeen, the Cultural Revolution began, and life as she knew it changed forever. One by one, her family members were scattered, sentenced to prison or labor camps. By 1969, the art schools had closed, and Xiao-Mei was on her way to a work camp in Mongolia, where she would spend the next five years. Life in the camp was nearly unbearable, thanks to horrific living conditions and intensive brainwashing campaigns. Yet through it all Xiao-Mei clung to her passion for music and her sense of humor. And when the Revolution ended, it was the piano that helped her to heal. Heartbreaking and heartwarming, The Secret Piano is the incredible true story of one woman’s survival in the face of unbelievable odds—and in pursuit of a powerful dream.

    Yet sometime near the end of the century, censors cut a section from "The Secret History of the Mongols, " leaving a single tantalizing quote from Genghis Khan: "Let us reward our female offspring." Only this hint of a father's legacy for his daughters remained of a much larger story. The queens of the Silk Route turned their father's conquests into the world's first truly international empire, fostering trade, education, and religion throughout their territories and creating an economic system that stretched from the Pacific to the Mediterranean. Outlandish stories of these powerful queens trickled out of the Empire, shocking the citizens of Europe and and the Islamic world. After Genghis Khan's death in 1227, conflicts erupted between his daughters and his daughters-in-law; what began as a war between powerful women soon became a war against women in power as brother turned against sister, son against mother. At the end of this epic struggle, the dynasty of the Mongol queens had seemingly been extinguished forever, as even their names were erased from the historical record.. One of the most unusual and important warrior queens of history arose to avenge the wrongs, rescue the tattered shreds of the Mongol Empire, and restore order to a shattered world. Putting on her quiver and picking up her bow, Queen Mandhuhai led her soldiers through victory after victory. In her thirties she married a seventeen-year-old prince, and she bore eight children in the midst of a career spent fighting the Ming Dynasty of China on one side and a series of Muslim warlords on the other. Her unprecedented success on the battlefield provoked the Chinese into the most frantic and expensive phase of wall building in history. Charging into battle even while pregnant, she fought to reassemble the Mongol Nation of Genghis Khan and to preserve it for her own children to rule in peace. At the conclusion of his magnificently researched and ground-breaking narrative, Weatherford notes that, despite their mystery and the efforts to erase them from our collective memory, the deeds of these Mongol queens inspired great artists from Chaucer and Milton to Goethe and Puccini, and so their stories live on today. With "The Secret History of the Mongol Queens," Jack Weatherford restores the queens' missing chapter to the annals of history.

    Navy SEALs left their base in northern Afghanistan for the mountainous Pakistani border. Their mission was to capture or kill a notorious al Qaeda leader known to be ensconced in a Taliban stronghold surrounded by a small but heavily armed force. Less then twenty-four hours later, only one of those Navy SEALs remained alive. This is the story of fire team leader Marcus Luttrell, the sole survivor of Operation Redwing, and the desperate battle in the mountains that led, ultimately, to the largest loss of life in Navy SEAL history. But it is also, more than anything, the story of his teammates, who fought ferociously beside him until he was the last one left-blasted unconscious by a rocket grenade, blown over a cliff, but still armed and still breathing. Over the next four days, badly injured and presumed dead, Luttrell fought off six al Qaeda assassins who were sent to finish him, then crawled for seven miles through the mountains before he was taken in by a Pashtun tribe, who risked everything to protect him from the encircling Taliban killers. A six-foot-five-inch Texan, Leading Petty Officer Luttrell takes us, blow-by-blow, through the brutal training of America's warrior elite and the relentless rites of passage required by the Navy SEALs. He transports us to a monstrous battle fought in the desolate peaks of Afghanistan, where the beleaguered American team plummeted headlong a thousand feet down a mountain as they fought back through flying shale and rocks. In this rich , moving chronicle of courage, honor, and patriotism, Marcus Luttrell delivers one of the most powerful narratives ever written about modern warfare-and a tribute to his teammates, who made the ultimate sacrifice for their country.

    It is also armed with nuclear weapons. Between 150,000 and 200,000 people are being held in its political prison camps, which have existed twice as long as Stalin's Soviet gulags and twelve times as long as the Nazi concentration camps. Very few born and raised in these camps have escaped. But Shin Donghyuk did.In Escape from Camp 14, acclaimed journalist Blaine Harden tells the story of Shin Dong-hyuk and through the lens of Shin's life unlocks the secrets of the world's most repressive totalitarian state. Shin knew nothing of civilized existence-he saw his mother as a competitor for food, guards raised him to be a snitch, and he witnessed the execution of his own family. Through Harden's harrowing narrative of Shin's life and remarkable escape, he offers an unequaled inside account of one of the world's darkest nations and a riveting tale of endurance, courage, and survival.

    It is an ugly, shameful story of being sold with her mother into slave marriages by Chinese brokers, and although she at first tried to hide the painful details when blending into South Korean society, she realized how her survival story could inspire others. Moreover, her sister had also escaped earlier and had vanished into China for years, prompting the author to go public with her story in the hope of finding her sister.

    Above all else, Cleopatra was a shrewd strategist and an ingenious negotiator.Though her life spanned fewer than forty years, it reshaped the contours of the ancient world. She was married twice, each time to a brother. She waged a brutal civil war against the first when both were teenagers. She poisoned the second. Ultimately she dispensed with an ambitious sister as well; incest and assassination were family specialties. Cleopatra appears to have had sex with only two men. They happen, however, to have been Julius Caesar and Mark Antony, among the most prominent Romans of the day. Both were married to other women. Cleopatra had a child with Caesar and–after his murder–three more with his protégé. Already she was the wealthiest ruler in the Mediterranean; the relationship with Antony confirmed her status as the most influential woman of the age. The two would together attempt to forge a new empire, in an alliance that spelled their ends. Cleopatra has lodged herself in our imaginations ever since.Famous long before she was notorious, Cleopatra has gone down in history for all the wrong reasons. Shakespeare and Shaw put words in her mouth. Michelangelo, Tiepolo, and Elizabeth Taylor put a face to her name. Along the way, Cleopatra’s supple personality and the drama of her circumstances have been lost. In a masterly return to the classical sources, Stacy Schiff here boldly separates fact from fiction to rescue the magnetic queen whose death ushered in a new world order. Rich in detail, epic in scope, Schiff ‘s is a luminous, deeply original reconstruction of a dazzling life.

    It has been translated into fifteen languages, sold more than 12 million copies, and is the basis for an award-winning German entry at the 2002 Cannes Film Festival. Recounting an incredible real-life adventure, it tracks the destiny of German soldier Clemens Forrell who, in the aftermath of WWII, was sentenced to twenty-five years of forced labor in a lead mine in the barren eastern reaches of Siberia.Subjected to the brutality of the camp and the climate, Forrell dreamed continuously of escape—and then daringly effected it. From East Cape across the vast trackless wastes of Siberia, for thousands of miles and three years, with fear as his most intimate companion, Forrell fled treachery and endured some of the most inhospitable conditions on earth. In a long series of taped interviews with esteemed German author Josef M. Bauer, Forrell unfolded his remarkable story of survival. Bauer not only reconstructs Forrell's arduous journey to the Iranian frontier and freedom; he also poignantly evokes the emotional content of Forrell's brave quest—emerging as an affecting portrait of a man who strove and triumphed against all odds.

    How is it, then, that today the former British colonial trading post is a thriving Asian metropolis with not only the world's number one airline, best airport, and busiest port of trade, but also the world's fourth–highest per capita real income?The story of that transformation is told here by Singapore's charismatic, controversial founding father, Lee Kuan Yew. Rising from a legacy of divisive colonialism, the devastation of the Second World War, and general poverty and disorder following the withdrawal of foreign forces, Singapore now is hailed as a city of the future. This miraculous history is dramatically recounted by the man who not only lived through it all but who fearlessly forged ahead and brought about most of these changes.Delving deep into his own meticulous notes, as well as previously unpublished government papers and official records, Lee details the extraordinary efforts it took for an island city–state in Southeast Asia to survive at that time.Lee explains how he and his cabinet colleagues finished off the communist threat to the fledgling state's security and began the arduous process of nation building: forging basic infrastructural roads through a land that still consisted primarily of swamps, creating an army from a hitherto racially and ideologically divided population, stamping out the last vestiges of colonial–era corruption, providing mass public housing, and establishing a national airline and airport.In this illuminating account, Lee writes frankly about his trenchant approach to political opponents and his often unorthodox views on human rights, democracy, and inherited intelligence, aiming always "to be correct, not politically correct." Nothing in Singapore escaped his watchful eye: whether choosing shrubs for the greening of the country, restoring the romance of the historic Raffles Hotel, or openly, unabashedly persuading young men to marry women as well educated as themselves. Today's safe, tidy Singapore bears Lee's unmistakable stamp, for which he is unapologetic: "If this is a nanny state, I am proud to have fostered one."Though Lee's domestic canvas in Singapore was small, his vigor and talent assured him a larger place in world affairs. With inimitable style, he brings history to life with cogent analyses of some of the greatest strategic issues of recent times and reveals how, over the years, he navigated the shifting tides of relations among America, China, and Taiwan, acting as confidant, sounding board, and messenger for them. He also includes candid, sometimes acerbic pen portraits of his political peers, including the indomitable Margaret Thatcher and Ronald Reagan, the poetry–spouting Jiang Zemin, and ideologues George Bush and Deng Xiaoping.Lee also lifts the veil on his family life and writes tenderly of his wife and stalwart partner, Kwa Geok Choo, and of their pride in their three children –– particularly the eldest son, Hsien Loong, who is now Singapore's deputy prime minister.For more than three decades, Lee Kuan Yew has been praised and vilified in equal measure, and he has established himself as a force impossible to ignore in Asian and international politics. From Third World to First offers readers a compelling glimpse into this visionary's heart, soul, and mind.

    We have been constrained by unwritten rules not to do so, by the robes of tradition and by the sanctity of our exclusive calling...But I feel it is time to speak out."Celebrated as the most successful geisha of her generation, Mineko Iwasaki was only five years old when she left her parents' home for the world of the geisha. For the next twenty-five years, she would live a life filled with extraordinary professional demands and rich rewards. She would learn the formal customs and language of the geisha, and study the ancient arts of Japanese dance and music. She would enchant kings and princes, captains of industry, and titans of the entertainment world, some of whom would become her dearest friends. Through great pride and determination, she would be hailed as one of the most prized geishas in Japan's history, and one of the last great practitioners of this now fading art form.In Geisha, a Life, Mineko Iwasaki tells her story, from her warm early childhood, to her intense yet privileged upbringing in the Iwasaki okiya (household), to her years as a renowned geisha, and finally, to her decision at the age of twenty-nine to retire and marry, a move that would mirror the demise of geisha culture. Mineko brings to life the beauty and wonder of Gion Kobu, a place that "existed in a world apart, a special realm whose mission and identity depended on preserving the time-honored traditions of the past." She illustrates how it coexisted within post-World War II Japan at a time when the country was undergoing its radical transformation from a post-feudal society to a modern one."There is much mystery and misunderstanding about what it means to be a geisha. I hope this story will help explain what it is really like and also serve as a record of this unique component of Japan's cultural history," writes Mineko Iwasaki. Geisha, a Life is the first of its kind, as it delicately unfolds the fabric of a geisha's development. Told with great wisdom and sensitivity, it is a true story of beauty and heroism, and of a time and culture rarely revealed to the Western world.

    The niece of Theodore Roosevelt, she married a distant relative and Columbia University law student named Franklin Delano Roosevelt; he gradually ascended throughout the world of New York politics to reach the U.S. presidency in 1932. Throughout his three terms, Eleanor Roosevelt was not only intimately involved in FDR’s personal and political life, but led women’s organizations and youth movements and fought for consumer welfare, civil rights, and improved housing. During World War II she traveled with her husband to meet leaders of many powerful nations; after his death in 1945 she worked as a UN delegate, chairman of the Commission on Human Rights, newspaper columnist, Democratic party activist, world-traveler, and diplomat. By the end of her life, Eleanor Roosevelt was recognized throughout the world for her fortitude and commitment to the ideals of liberty and human rights. Her autobiography constitutes a self-portrait no biography can match for its candor and liveliness, its wisdom, tolerance, and breadth of view—a self-portrait of one of the greatest American humanitarians of our time.

    Her background made her an obvious target for the fanatics of the Cultural Revolution: educated in London, the widow of an official of Chiang Kai-Shek's regime, and an employee of Shell Oil, Nien Cheng enjoyed comforts that few of her compatriots could afford. When she refused to confess that any of this made her an enemy of the state, she was placed in solitary confinement, where she would remain for more than six years. "Life and Death in Shanghai" is the powerful story of Nien Cheng's imprisonment, of the deprivation she endured, of her heroic resistance, and of her quest for justice when she was released. It is the story, too, of a country torn apart by the savage fight for power Mao Tse-tung launched in his campaign to topple party moderates. An incisive, rare personal account of a terrifying chapter in twentieth-century history, "Life and Death in Shanghai" is also an astounding portrait of one woman's courage.

    In this brave and searingly frank memoir, she describes those first horrifying moments and her long journey since. She has written an engrossing, unsentimental, beautifully poised account: as she struggles through the first months following the tragedy, furiously clenched against a reality that she cannot face and cannot deny; and then, over the ensuing years, as she emerges reluctantly, slowly allowing her memory to take her back through the rich and joyous life she’s mourning, from her family’s home in London, to the birth of her children, to the year she met her English husband at Cambridge, to her childhood in Colombo; all the while learning the difficult balance between the almost unbearable reminders of her loss and the need to keep her family, somehow, still alive within her.

    Comedy legends and A-list actors. Supermodels and centerfolds. Moguls and mobsters. A president.Over his unrivaled four-decade career in radio, Howard Stern has interviewed thousands of personalities—discussing sex, relationships, money, fame, spirituality, and success with the boldest of bold-faced names. But which interviews are his favorites? It’s one of the questions he gets asked most frequently. Howard Stern Comes Again delivers his answer.This book is a feast of conversation and more, as between the lines Stern offers his definitive autobiography—a magnum opus of confession and personal exploration. Tracy Morgan opens up about his near-fatal car crash. Lady Gaga divulges her history with cocaine. Madonna reminisces on her relationship with Tupac Shakur. Bill Murray waxes philosophical on the purpose of life. Jerry Seinfeld offers a master class on comedy. Harvey Weinstein denies the existence of the so-called casting couch. An impressive array of creative visionaries weigh in on what Stern calls “the climb”—the stories of how they struggled and eventually prevailed. As he writes in the introduction, “If you’re having trouble finding motivation in life and you’re looking for that extra kick in the ass, you will find it in these pages.”Interspersed throughout are rare selections from the Howard Stern Show archives with Donald Trump that depict his own climb: transforming from Manhattan tabloid fixture to reality TV star to president of the United States. Stern also tells of his Moby Dick-like quest to land an interview with Hillary Clinton in the run-up to the 2016 election—one of many newly written revelations from the author. He speaks with extraordinary candor about a variety of subjects, including his overwhelming insecurity early in his career, his revolutionary move from terrestrial radio to SiriusXM, and his belief in the power of psychotherapy.As Stern insightfully notes in the introduction: “The interviews collected here represent my best work and show my personal evolution. But they don’t just show my evolution. Gathered together like this, they show the evolution of popular culture over the past quarter century.”