She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    The Parisian episode is fascinating for its expose of the kitchens of posh French restaurants, where the narrator works at the bottom of the culinary echelon as dishwasher, or plongeur. In London, while waiting for a job, he experiences the world of tramps, street people, and free lodging houses. In the tales of both cities we learn some sobering Orwellian truths about poverty and of society.

    She had a play that was to be produced at the New York International Fringe Festival and a job waiting for her at the New Yorker. Tragically, five days after graduation, Marina died in a car crash.As her family, friends, and classmates, deep in grief, joined to create a memorial service for Marina, her unforgettable last essay for the Yale Daily News, “The Opposite of Loneliness,” went viral, receiving more than 1.4 million hits. She had struck a chord.Even though she was just twenty-two when she died, Marina left behind a rich, expansive trove of prose that, like her title essay, captures the hope, uncertainty, and possibility of her generation. The Opposite of Loneliness is an assem­blage of Marina’s essays and stories that, like The Last Lecture, articulates the universal struggle that all of us face as we figure out what we aspire to be and how we can harness our talents to make an impact on the world.

    Set during the tumult of World War II, on the lush Malayan island of Penang, The Gift of Rain tells a riveting and poignant tale about a young man caught in the tangle of wartime loyalties and deceits.

    At once a love story & a harrowing account of one man’s long walk home, Cold Mountain introduces a new talent in American literature.Based on local history & family stories passed down by Frazier’s great-great-grandfather, Cold Mountain is the tale of a wounded Confederate soldier, Inman, who walks away from the ravages of the war & back home to his prewar sweetheart, Ada. His odyssey thru the devastated landscape of the soon-to-be-defeated South interweaves with Ada’s struggle to revive her father’s farm, with the help of an intrepid young drifter named Ruby. As their long-separated lives begin to converge at the close of the war, Inman & Ada confront the vastly transformed world they’ve been delivered.Frazier reveals insight into human relations with the land & the dangers of solitude. He also shares with the great 19th century novelists a keen observation of a society undergoing change. Cold Mountain recreates a world gone by that speaks to our time.

    The Wood family is much like its close, Catholic, immigrant neighbors, all dependent on a father’s wages from the Oxford Paper Company. Until the sudden death of Dad, when Mum and the four closely connected Wood girls are set adrift. Funny and to-the-bone moving, When We Were the Kennedys is the story of how this family saves itself, at first by depending on Father Bob, Mum’s youngest brother, a charismatic Catholic priest who feels his new responsibilities deeply. And then, as the nation is shocked by the loss of its handsome Catholic president, the televised grace of Jackie Kennedy—she too a Catholic widow with young children—galvanizes Mum to set off on an unprecedented family road trip to Washington, D.C., to do some rescuing of her own. An indelible story of how family and nation, each shocked by the unimaginable, exchange one identity for another.

    It has been boarded up for decades, but now the new owner has discovered the belongings of Japanese families who were sent to internment camps during World War II. As the owner displays and unfurls a Japanese parasol, Henry, a Chinese American, remembers a young Japanese American girl from his childhood in the 1940s—Keiko Okabe, with whom he forged a bond of friendship and innocent love that transcended the prejudices of their Old World ancestors. After Keiko and her family were evacuated to the internment camps, she and Henry could only hope that their promise to each other would be kept. Now, forty years later, Henry explores the hotel's basement for the Okabe family's belongings and for a long-lost object whose value he cannot even begin to measure. His search will take him on a journey to revisit the sacrifices he has made for family, for love, for country.

    Its architectural treasures crumble—foundations shift, marble ornaments fall—even as efforts to preserve them are underway. The City of Falling Angels opens on the evening of January 29, 1996, when a dramatic fire destroys the historic Fenice opera house. The loss of the Fenice, where five of Verdi's operas premiered, is a catastrophe for Venetians. Arriving in Venice three days after the fire, Berendt becomes a kind of detective—inquiring into the nature of life in this remarkable museum-city—while gradually revealing the truth about the fire.In the course of his investigations, Berendt introduces us to a rich cast of characters: a prominent Venetian poet whose shocking "suicide" prompts his skeptical friends to pursue a murder suspect on their own; the first family of American expatriates that loses possession of the family palace after four generations of ownership; an organization of high-society, partygoing Americans who raise money to preserve the art and architecture of Venice, while quarreling in public among themselves, questioning one another's motives and drawing startled Venetians into the fray; a contemporary Venetian surrealist painter and outrageous provocateur; the master glassblower of Venice; and numerous others-stool pigeons, scapegoats, hustlers, sleepwalkers, believers in Martians, the Plant Man, the Rat Man, and Henry James.Berendt tells a tale full of atmosphere and surprise as the stories build, one after the other, ultimately coming together to reveal a world as finely drawn as a still-life painting. The fire and its aftermath serve as a leitmotif that runs throughout, adding the elements of chaos, corruption, and crime and contributing to the ever-mounting suspense of this brilliant book.

    But it's time now to think on it anew. There's a journey we must go on, and no more delay..."The Buried Giant begins as a couple set off across a troubled land of mist and rain in the hope of finding a son they have not seen in years.Sometimes savage, often intensely moving, Kazuo Ishiguro's first novel in nearly a decade is about lost memories, love, revenge, and war.Included on TIME Magazine's "THE 100 BEST FANTASY BOOKS OF ALL TIME"

    Yet by the end of World War II, almost the only thing remaining of their vast empire was a collection of 264 wood and ivory carvings, none of them larger than a matchbox.The renowned ceramicist Edmund de Waal became the fifth generation to inherit this small and exquisite collection of netsuke. Entranced by their beauty and mystery, he determined to trace the story of his family through the story of the collection.The netsuke—drunken monks, almost-ripe plums, snarling tigers—were gathered by Charles Ephrussi at the height of the Parisian rage for all things Japanese. Charles had shunned the place set aside for him in the family business to make a study of art, and of beautiful living. An early supporter of the Impressionists, he appears, oddly formal in a top hat, in Renoir’s Luncheon of the Boating Party. Marcel Proust studied Charles closely enough to use him as a model for the aesthete and lover Swann in Remembrance of Things Past.Charles gave the carvings as a wedding gift to his cousin Viktor in Vienna; his children were allowed to play with one netsuke each while they watched their mother, the Baroness Emmy, dress for ball after ball. Her older daughter grew up to disdain fashionable society. Longing to write, she struck up a correspondence with Rilke, who encouraged her in her poetry.The Anschluss changed their world beyond recognition. Ephrussi and his cosmopolitan family were imprisoned or scattered, and Hitler’s theorist on the “Jewish question” appropriated their magnificent palace on the Ringstrasse. A library of priceless books and a collection of Old Master paintings were confiscated by the Nazis. But the netsuke were smuggled away by a loyal maid, Anna, and hidden in her straw mattress. Years after the war, she would find a way to return them to the family she’d served even in their exile.In The Hare with Amber Eyes, Edmund de Waal unfolds the story of a remarkable family and a tumultuous century. Sweeping yet intimate, it is a highly original meditation on art, history, and family, as elegant and precise as the netsuke themselves.

    But there is a dark and vacuous hole in her heart, and it isn’t just the loss of her parents, or the way her Wall Street boyfriend treats her, or her sadomasochistic relationship with her best friend, Reva. It’s the year 2000 in a city aglitter with wealth and possibility; what could be so terribly wrong?My Year of Rest and Relaxation is a powerful answer to that question. Through the story of a year spent under the influence of a truly mad combination of drugs designed to heal our heroine from her alienation from this world, Moshfegh shows us how reasonable, even necessary, alienation can be. Both tender and blackly funny, merciless and compassionate, it is a showcase for the gifts of one of our major writers working at the height of her powers.

    The Grimke’s daughter, Sarah, has known from an early age she is meant to do something large in the world, but she is hemmed in by the limits imposed on women.Kidd’s sweeping novel is set in motion on Sarah’s eleventh birthday, when she is given ownership of ten year old Handful, who is to be her handmaid. We follow their remarkable journeys over the next thirty five years, as both strive for a life of their own, dramatically shaping each other’s destinies and forming a complex relationship marked by guilt, defiance, estrangement and the uneasy ways of love.As the stories build to a riveting climax, Handful will endure loss and sorrow, finding courage and a sense of self in the process. Sarah will experience crushed hopes, betrayal, unrequited love, and ostracism before leaving Charleston to find her place alongside her fearless younger sister, Angelina, as one of the early pioneers in the abolition and women’s rights movements.Inspired by the historical figure of Sarah Grimke, Kidd goes beyond the record to flesh out the rich interior lives of all of her characters, both real and invented, including Handful’s cunning mother, Charlotte, who courts danger in her search for something better.This exquisitely written novel is a triumph of storytelling that looks with unswerving eyes at a devastating wound in American history, through women whose struggles for liberation, empowerment, and expression will leave no reader unmoved.

    The other has ideas: about rhythm and time, about black bodies and black music, about what constitutes a tribe, or makes a person truly free. It's a close but complicated childhood friendship that ends abruptly in their early twenties, never to be revisited, but never quite forgotten, either.Dazzlingly energetic and deeply human, Swing Time is a story about friendship and music and stubborn roots, about how we are shaped by these things and how we can survive them. Moving from northwest London to West Africa, it is an exuberant dance to the music of time.

    Born with red pupils, he was called “Devil Boy” or Sam “Hell” by his classmates; “God’s will” is what his mother called his ocular albinism. Her words were of little comfort, but Sam persevered, buoyed by his mother’s devout faith, his father’s practical wisdom, and his two other misfit friends.Sam believed it was God who sent Ernie Cantwell, the only African American kid in his class, to be the friend he so desperately needed. And that it was God’s idea for Mickie Kennedy to storm into Our Lady of Mercy like a tornado, uprooting every rule Sam had been taught about boys and girls.Forty years later, Sam, a small-town eye doctor, is no longer certain anything was by design—especially not the tragedy that caused him to turn his back on his friends, his hometown, and the life he’d always known. Running from the pain, eyes closed, served little purpose. Now, as he looks back on his life, Sam embarks on a journey that will take him halfway around the world. This time, his eyes are wide open—bringing into clear view what changed him, defined him, and made him so afraid, until he can finally see what truly matters.

    After a childhood moving from one academic outpost to another with her father (a man prone to aphorisms and meteoric affairs), Blue is clever, deadpan, and possessed of a vast lexicon of literary, political, philosophical, and scientific knowledge—and is quite the cineaste to boot. In her final year of high school at the elite (and unusual) St. Gallway School in Stockton, North Carolina, Blue falls in with a charismatic group of friends and their captivating teacher, Hannah Schneider. But when the drowning of one of Hannah's friends and the shocking death of Hannah herself lead to a confluence of mysteries, Blue is left to make sense of it all with only her gimlet-eyed instincts and cultural references to guide—or misguide—her.