We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    There's no need to look through dozens of photos of birds that don't live in Michigan. This book features 112 species of Michigan birds, organized by color for ease of use. Do you see a yellow bird and don't know what it is? Go to the yellow section to find out. Fact-filled information, a compare feature, range maps and detailed photographs help to ensure that you positively identify the birds that you see.

    Now in The Undiscovered Mind he focuses on the single most important scientific enterprise of all -- the effort to understand the human mind. Horgan takes us inside laboratories, hospitals, and universities to meet neuro-scientists, Freudian analysts, electroshock therapists, behavioral geneticists, evolutionary psychologists, artificial intelligence engineers, and philosophers of consciousness. He looks into the persistent explanatory gap between mind and body that Socrates pondered and shows that it has not been bridged. He investigates what he calls the "Humpty Dumpty dilemma," the fact that neuroscientists can break the brain and mind into pieces but cannot put the pieces back together again. He presents evidence that the placebo effect is the primary ingredient of psychotherapy, Prozac, and other treatments for mental disorders. As Horgan shows, the mystery of human consciousness, of why and how we think, remains so impregnable that to expect the attempts of scientific method and technology to penetrate it anytime soon is absurd.

    With a logical, body-systems organization and engaging terminology exercises throughout, it's your key to communicating confidently and effectively with other health care professionals.Systematic approach to terminology prepares you to recognize and define new words as you encounter them and build the medical vocabulary you'll need in the health care setting.Pronunciation key provides quick access to frequently referenced material.Complimentary and Alternative Medicine terms boxes highlight words and phrases associated with this increasingly popular discipline.Case studies encourage critical thinking and demonstrate how to apply the information you've learned.Terminology flash cards, included with every book, give you valuable review and self-assessment tools you can take anywhere for study on the go.Evolve resources enhance your learning and reinforcement opportunities with additional exercises, a Spanish/English glossary, and the Body Spectrum Electronic Anatomy Coloring Book.Medical Terminology Online, available at an additional charge, gives you access to a complete online course for the most advanced learning and understanding.New terms and abbreviations familiarize you with the latest terminology in use in health care.New images and illustrations visually acquaint you with pathologic information and procedures you'll encounter in the clinical setting.Enhanced chapter features highlight important concepts and provide guidance for more effective learning and study.CD references within the text direct you to expanded learning opportunities on the companion CD.More than 20 new medical records let you practice medical terminology using the forms you'll encounter in the clinical setting.New icons make it easy to distinguish a variety of helpful boxes and reference the material you need quickly.Answers to review exercises help you gauge your strengths and weaknesses and configure the most effective study plan for you.Website boxes refer you to valuable content you can access online for further learning.Revised pharmacy appendix helps you easily reference key pharmaceutical terms.The vastly updated companion CD provides fun alternatives for reinforcing what you've learned with new learning games, including Medical Millionaire and Termbusters.Enhanced audio companion, available on CD or as iTerms downloads for portable media players, helps you perfect your pronunciation skills and confidently use the terms you've learned in practice.

    Mark Plaster takes readers beyond the ambulance bay doors into the stranger-than-fiction world of the Emergency Department. By turns heart-warming and gut-wrenching, "Night Shift" chronicles the ebb and flow of human life, in all of its unvarnished glory, as it passes through the doors of the ED.

    The metric gives unparalleled insight into which teams and players are performing at the highest level.Professional gamblers have used Expected Goals to make millions through football betting. Club scouts have used Expected Goals to identify hidden gems in the transfer market. And the media have recently started using Expected Goals to offer more profound insight in their broadcasts.Despite this, most ordinary fans still don’t understand what the Expected Goals method is – or appreciate the significant impact that it is set to have on the sport in coming years.Expected Goals (otherwise known as xG) was originally conjured up by a small corner of the online football analytics community. It didn’t take long for professional gamblers to begin using xG to predict match outcomes. These bettors utilised the Expected Goals method to turn over hundreds of millions of pounds from the bookmakers.Before long, football clubs had caught on to the ground-breaking insight given by xG. Brentford FC were leaders in this field, managing to assemble a Play-Off-reaching squad on a shoe-string budget. In the last five years, the small West London side have turned over more than £100m in transfer profit from their use of the Expected Goals method in player recruitment.More recently, the Expected Goals method has been adopted by the media as a form of insight. Fans are finally catching on to the pioneering means of football analysis. Soon enough, anyone who doesn’t understand the Expected Goals philosophy will be left behind.“This book will make you watch football differently” – Tobias Pedersen“Possibly the most ground-breaking football book ever written” – Football Impact“A brilliant account of the history and future of Expected Goals” – StatShot

    The Chronic Cough Enigma is written for people who have been coughing for months or years and cannot get useful answers from their doctors.More than 20 million Americans suffer from what is known as enigmatic chronic cough. This book provides insights from Dr. Jamie Koufman’s almost forty years of successfully managing thousands of long-suffering cough patients. Indeed, the typical chronic cough patient who comes to her office has been coughing for more than a decade. This book provides the many who suffer from chronic cough new and potentially life-changing information and the potential to be cured.

    As a moral philosopher, Joyce is interested in whether any implications follow from this hypothesis. Might the fact that the human brain has been biologically prepared by natural selection to engage in moral judgment serve in some sense to vindicate this way of thinking -- staving off the threat of moral skepticism, or even undergirding some version of moral realism? Or if morality has an adaptive explanation in genetic terms -- if it is, as Joyce writes, "just something that helped our ancestors make more babies" -- might such an explanation actually undermine morality's central role in our lives? He carefully examines both the evolutionary "vindication of morality" and the evolutionary "debunking of morality," considering the skeptical view more seriously than have others who have treated the subject.Interdisciplinary and combining the latest results from the empirical sciences with philosophical discussion, The Evolution of Morality is one of the few books in this area written from the perspective of moral philosophy. Concise and without technical jargon, the arguments are rigorous but accessible to readers from different academic backgrounds. Joyce discusses complex issues in plain language while advocating subtle and sometimes radical views. The Evolution of Morality lays the philosophical foundations for further research into the biological understanding of human morality.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    But when Paco was struck down by a disease that left him unable to walk, Hickam was faced with a terrible decision, let his beloved cat live in misery or put him to sleep. Before that decision could be made, the space mission Hickam was working on needed to be rescued and there was only one sure way to save it: Paco's magic meow! This is a true story of the space age that is also a delightful tale of the love between an engineer and his cat.

    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

    This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory.The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.

    In The Botany of Desire, Michael Pollan ingeniously demonstrates how people and domesticated plants have formed a similarly reciprocal relationship. He masterfully links four fundamental human desires—sweetness, beauty, intoxication, and control—with the plants that satisfy them: the apple, the tulip, marijuana, and the potato. In telling the stories of four familiar species, Pollan illustrates how the plants have evolved to satisfy humankind’s most basic yearnings. And just as we’ve benefited from these plants, we have also done well by them. So who is really domesticating whom?

    Maybe it's made of silicon! Maybe it has wheels! Or maybe it doesn't. In The Equations of Life, biologist Charles S. Cockell makes the forceful argument that the laws of physics narrowly constrain how life can evolve, making evolution's outcomes predictable. If we were to find on a distant planet something very much like a lady bug eating something like an aphid, we shouldn't be surprised. The forms of life are guided by a limited set of rules, and as a result, there is a narrow set of solutions to the challenges of existence.A remarkable scientific contribution breathing new life into Darwin's theory of evolution, The Equations of Life makes a radical argument about what life can -- and can't -- be.