The trilobites, which dominated the ocean floors for 300 million years, are gone. The last of the dinosaurs was wiped out by a Mount Everest-sized meteorite that slammed into the earth 65 million years ago. The great flying reptiles are gone, and so are the marine reptiles, some of them larger than a humpback whale. Before humans crossed the Bering land bridge some 15,000 years ago, North America was populated by mastodons, mammoths, saber-toothed tigers, and cave bears. They too are MIA. Passenger pigeons once flew over North America in flocks that numbered in the billions; the last one died in 1914.In this book you will meet creatures that were driven to extinction even more recently, as well as some that were brought back from the brink. You will even encounter animals not known to exist until recently -- an antidote to extinction.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    It will never fail you." When Frank Lloyd Wright said this, he probably wasn't envisioning self-cleaning surfaces, the photonic crystal, or Velcro. But nature has indeed yielded such inventions for those scientists and engineers who heeded the architect's words.The cutting-edge science of bio-inspiration gives way to architectural and product designs that mimic intricate mechanisms found in nature. In Peter Forbes's engaging book we discover that the spiny fruits of the cocklebur inspired the hook-and-loop fastener known as Velcro; unfolding leaves, insect wings, and space solar panels share similar origami folding patterns; the self-cleaning leaves of the sacred lotus plant have spawned a new industry of self-cleaning surfaces; and cantilever bridges have much in common with bison spines.As we continue to study nature, bio-inspiration will transform our lives and force us to look at the world in a new way.

    B&W photos throughout. Full-color insert.

    These bacteria are everywhere: in and on our bodies, in homes, schools, hospitals, crowded airplanes, day-care centers. And, as The Killers Within makes frighteningly clear, so far the bacteria are winning.

    With the Big Bang, it went from a state of unimaginable density to an all-encompassing cosmic fireball to a simmering fluid of matter and energy, laying down the seeds for everything from dark matter to black holes to one rocky planet orbiting a star near the edge of a spiral galaxy that happened to develop life. But what happens at the end of the story? In billions of years, humanity could still exist in some unrecognizable form, venturing out to distant space, finding new homes and building new civilizations. But the death of the universe is final. What might such a cataclysm look like? And what does it mean for us? Dr. Katie Mack has been contemplating these questions since she was eighteen, when her astronomy professor first informed her the universe could end at any moment, setting her on the path toward theoretical astrophysics. Now, with lively wit and humor, she unpacks them in The End of Everything, taking us on a mind-bending tour through each of the cosmos’ possible finales: the Big Crunch; the Heat Death; Vacuum Decay; the Big Rip; and the Bounce. In the tradition of Neil DeGrasse’s bestseller Astrophysics for People in a Hurry, Mack guides us through major concepts in quantum mechanics, cosmology, string theory, and much more, in a wildly fun, surprisingly upbeat ride to the farthest reaches of everything we know.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    In this beautiful new one-volume edition, modern readers are introduced to one of the best nature writers of the last century. More than one hundred of the original illustrations by Paul Landacre highlight the eloquent and entertaining accounts of American trees. As we read Peattie's descriptions, we catch glimpses of our country's history and past daily life that no textbook could ever illuminate so vividly.Here you'll learn about everything from how a species was discovered to the part it played in our country’s history. Pioneers often stabled an animal in the hollow heart of an old sycamore, and the whole family might live there until they could build a log cabin. The tuliptree, the tallest native hardwood, is easier to work than most softwood trees; Daniel Boone carved a sixty-foot canoe from one tree to carry his family from Kentucky into Spanish territory. In the days before the Revolution, the British and the colonists waged an undeclared war over New England's white pines, which made the best tall masts for fighting ships. It's fascinating to learn about the commercial uses of various woods -- for paper, fine furniture, fence posts, matchsticks, house framing, airplane wings, and dozens of other preplastic uses. But we cannot read this book without the occasional lump in our throats. The American elm was still alive when Peattie wrote, but as we read his account today we can see what caused its demise. Audubon's portrait of a pair of loving passenger pigeons in an American beech is considered by many to be his greatest painting. It certainly touched the poet in Donald Culross Peattie as he depicted the extinction of the passenger pigeon when the beech forest was destroyed. A Natural History of North American Trees gives us a picture of life in America from its earliest days to the middle of the last century. The information is always interesting, though often heartbreaking. While Peattie looks for the better side of man's nature, he reports sorrowfully on the greed and waste that have doomed so much of America's virgin forest.

    So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.

    In Elephants on Acid, Boese details the results of this scientific trial, as well as answers to the questions: Why can't people tickle themselves? Would the average dog summon help in an emergency? Will babies instinctually pick a well-balanced diet? Is it possible to restore life to the dead? Read on to find out...

    In The Ends of the World, Peter Brannen dives into deep time, exploring Earth’s past dead ends, and in the process, offers us a glimpse of our possible future.Many scientists now believe that the climate shifts of the twenty-first century have analogs in these five extinctions. Using the visible clues these devastations have left behind in the fossil record, The Ends of the World takes us inside “scenes of the crime,” from South Africa to the New York Palisades, to tell the story of each extinction. Brannen examines the fossil record—which is rife with creatures like dragonflies the size of sea gulls and guillotine-mouthed fish—and introduces us to the researchers on the front lines who, using the forensic tools of modern science, are piecing together what really happened at the crime scenes of the Earth’s biggest whodunits.Part road trip, part history, and part cautionary tale, The Ends of the World takes us on a tour of the ways that our planet has clawed itself back from the grave, and casts our future in a completely new light.

    From the minds of the world's leading physicists there flowed a river of ideas that would transport mankind to the pinnacle of wonderment and to the very depths of human despair. This was a century that began with the certainties of absolute knowledge and ended with the knowledge of absolute uncertainty. It was a century in which physicists developed weapons with the capacity to destroy our reality, whilst at the same time denying us the possibility that we can ever properly comprehend it.Almost everything we think we know about the nature of our world comes from one theory of physics. This theory was discovered and refined in the first thirty years of the twentieth century and went on to become quite simply the most successful theory of physics ever devised. Its concepts underpin much of the twenty-first century technology that we have learned to take for granted. But its success has come at a price, for it has at the same time completely undermined our ability to make sense of the world at the level of its most fundamental constituents.Rejecting the fundamental elements of uncertainty and chance implied by quantum theory, Albert Einstein once famously declared that 'God does not play dice'. Niels Bohr claimed that anybody who is not shocked by the theory has not understood it. The charismatic American physicist Richard Feynman went further: he claimed that nobody understands it.This is quantum theory, and this book tells its story.Jim Baggott presents a celebration of this wonderful yet wholly disconcerting theory, with a history told in forty episodes -- significant moments of truth or turning points in the theory's development. From its birth in the porcelain furnaces used to study black body radiation in 1900, to the promise of stimulating new quantum phenomena to be revealed by CERN's Large Hadron Collider over a hundred years later, this is the extraordinary story of the quantum world.Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

    This updated edition includes a new Introduction and a new final chapter exposing frightening developments in recent years, including the black market that emerged in chemical and biological weapons following the breakup of the Soviet Union, the acquisition of these weapons by various Third World states, the attempts of countries such as Iraq to build up arsenals, and--particularly and most recently--the use of these weapons in terrorist attacks.