She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    He offers a vivid, historical tour of our willingness to suspend reason in favor of religious beliefs—even when these beliefs inspire the worst human atrocities. While warning against the encroachment of organized religion into world politics, Harris draws on insights from neuroscience, philosophy, and Eastern mysticism to deliver a call for a truly modern foundation for ethics and spirituality that is both secular and humanistic.Winner of the 2005 PEN/Martha Albrand Award for Nonfiction.

    What followed was a rigorous, pathbreaking, and enthralling exchange, which has been viewed millions of times since it was first posted on YouTube. This is intellectual inquiry at its best: exhilarating, funny, and unpredictable, sincere and probing, reminding us just how varied and colorful the threads of modern atheism are. Here is the transcript of that conversation, in print for the first time, augmented by material from the living participants: Dawkins, Harris, and Dennett. These new essays, introduced by Stephen Fry, mark the evolution of their thinking and highlight particularly resonant aspects of this epic exchange. Each man contends with the most fundamental questions of human existence while challenging the others to articulate their own stance on God and religion, cultural criticism, spirituality, debate with people of faith, and the components of a truly ethical life.

    In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast?Breaking down this monolithic business into the individual industries--the hospitals, doctors, insurance companies, and drug manufacturers--that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw.The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Communities where heroin had never been seen before—from Charlotte, NC and Huntington, WVA, to Salt Lake City and Portland, OR—were overrun with it. Local police and residents were stunned. How could heroin, long considered a drug found only in the dense, urban environments along the East Coast, and trafficked into the United States by enormous Colombian drug cartels, be so incredibly ubiquitous in the American heartland? Who was bringing it here, and perhaps more importantly, why were so many townspeople suddenly eager for the comparatively cheap high it offered?With the same dramatic drive of El Narco and Methland, Sam Quinones weaves together two classic tales of American capitalism: The stories of young men in Mexico, independent of the drug cartels, in search of their own American Dream via the fast and enormous profits of trafficking cheap black-tar heroin to America’s rural and suburban addicts; and that of Purdue Pharma in Stamford, Connecticut, determined to corner the market on pain with its new and expensive miracle drug, Oxycontin; extremely addictive in its own right. Quinones illuminates just how these two stories fit together as cause and effect: hooked on costly Oxycontin, American addicts were lured to much cheaper black tar heroin and its powerful and dangerous long-lasting high. Embroiled alongside the suppliers and buyers are DEA agents, local, small-town sheriffs, and the US attorney from eastern Virginia whose case against Purdue Pharma and Oxycontin made him an enemy of the Bush-era Justice Department, ultimately stalling and destroying his career in public service.Dreamland is a scathing and incendiary account of drug culture and addiction spreading to every part of the American landscape.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    It is an integral part of their marriage, child rearing, and community. In this daring new book, distinguished philosopher Daniel C. Dennett takes a hard look at this phenomenon and asks why. Where does our devotion to God come from and what purpose does it serve? Is religion a blind evolutionary compulsion or a rational choice? In "Breaking the Spell," Dennett argues that the time has come to shed the light of science on the fundamental questions of faith. In a spirited narrative that ranges widely through history, philosophy, and psychology, Dennett explores how organized religion evolved from folk beliefs and why it is such a potent force today. Deftly and lucidly, he contends that the "belief in belief" has fogged any attempt to rationally consider the existence of God and the relationship between divinity and human need."Breaking the Spell" is not an antireligious screed but rather an eyeopening exploration of the role that belief plays in our lives, our interactions, and our country. With the gulf between rationalists and adherents of "intelligent design" widening daily, Dennett has written a timely and provocative book that will be read and passionately debated by believers and nonbelievers alike.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    He eviscerates the major arguments for religion, and demonstrates the supreme improbability of a supreme being. He shows how religion fuels war, foments bigotry, and abuses children, buttressing his points with historical and contemporary evidence.The God Delusion makes a compelling case that belief in God is not just wrong, but potentially deadly. It also offers exhilarating insight into the advantages of atheism to the individual and society, not the least of which is a clearer, truer appreciation of the universe's wonders than any faith could ever muster.

    With bracing candor, the brilliant, charismatic, and uncompromising author of the bestselling Infidel and Nomad argues that it is foolish to insist, as our leaders habitually do, that the violent acts of Islamic extremists can be divorced from the religious doctrine that inspires them. Instead we must confront the fact that they are driven by a political ideology embedded in Islam itself.Today, Hirsi Ali argues, the world's 1.6 billion Muslims can be divided into a minority of extremists, a majority of observant but peaceable Muslims, and a few dissidents who risk their lives by questioning their own religion. But there is only one Islam, and as Hirsi Ali shows, there is no denying that some of its key teachings—not least the duty to wage holy war—inspire violence not just in the Muslim world but in the West as well.For centuries it has seemed that Islam is immune to historical change. But Hirsi Ali is surprisingly optimistic. She has come to believe that a Muslim "Reformation"—a revision of Islamic doctrine aimed at reconciling the religion with modernity—is at hand, and may even already have begun.Partly in response to the barbaric atrocities of Islamic State and Boko Haram, Muslims around the world have at last begun to speak out for religious reform. Meanwhile, events in the West, such as the shocking Charlie Hebdo massacre, have forced Western liberals to recognize that political Islam poses a mortal threat to free speech. Yet neither Muslim reformers nor Western liberals have so far been able to articulate a coherent program for a Muslim Reformation.This is where Heretic comes in. Boldly challenging centuries of theological orthodoxy, Ayaan Hirsi Ali proposes five key amendments to Islamic doctrine that Muslims must make if they are to bring their religion out of the seventh century and into the twenty-first. She also calls upon the Western world to end its appeasement of radical Islamists—and to drop the bogus argument that those who stand up to them are guilty of "Islamophobia." It is the Muslim reformers who need our backing, she argues, not the opponents of free speech.Interweaving her own experiences, historical analogies, and powerful examples from contemporary Muslim societies and cultures, Heretic is not so much a call to arms as a passionate plea for peaceful change and a new era of global tolerance. As jihadists kill thousands, from Nigeria to Syria to Pakistan, this book offers an answer to what is fast becoming the world's number one problem.

    But more than a temperament, being positive, we are told, is the key to success and prosperity. In this utterly original take on the American frame of mind, Barbara Ehrenreich traces the strange career of our sunny outlook from its origins as a marginal nineteenth-century healing technique to its enshrinement as a dominant, almost mandatory, cultural attitude. Evangelical mega-churches preach the good news that you only have to want something to get it, because God wants to "prosper" you. The medical profession prescribes positive thinking for its presumed health benefits. Academia has made room for new departments of "positive psychology" and the "science of happiness." Nowhere, though, has bright-siding taken firmer root than within the business community, where, as Ehrenreich shows, the refusal even to consider negative outcomes—like mortgage defaults—contributed directly to the current economic crisis.With the myth-busting powers for which she is acclaimed, Ehrenreich exposes the downside of America’s penchant for positive thinking: On a personal level, it leads to self-blame and a morbid preoccupation with stamping out “negative” thoughts. On a national level, it’s brought us an era of irrational optimism resulting in disaster. This is Ehrenreich at her provocative best—poking holes in conventional wisdom and faux science, and ending with a call for existential clarity and courage.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Christopher Hitchens continues to make the case for a splendidly godless universe in this first-ever gathering of the influential voices--past and present--that have shaped his side of the current (and raging) God/no-god debate. With Hitchens as your erudite and witty guide, you'll be led through a wealth of philosophy, literature, and scientific inquiry, including generous portions of the words of Lucretius, Benedict de Spinoza, Charles Darwin, Karl Marx, Mark Twain, George Eliot, Bertrand Russell, Emma Goldman, H. L. Mencken, Albert Einstein, Daniel Dennett, Sam Harris, Richard Dawkins, and many others well-known and lesser known. And they're all set in context and commented upon as only Christopher Hitchens political and literary journalist extraordinaire can.” (Los Angeles Times) Atheist? Believer? Uncertain? No matter: The Portable Atheist will speak to you and engage you every step of the way.