The first is the astonishing achievement of the Human Genome Project, which, it was anticipated, would identify the genetic basis of those characteristics that distinguish humans from their primate cousins. The second is the phenomenal advance in brain imaging that now permits neuroscientists to observe the brain 'in action' and thus account for the remarkable properties of the human mind.But that is not how it has turned out. It is simply not possible to get from the monotonous sequence of genes along the Double Helix to the near infinite diversity of the living world, nor to translate the electrical firing of the brain into the creativity of the human mind. This is not a matter of not knowing all the facts. Rather, science has inadvertently discovered that its theories are insufficient to conjure the wonder of the human experience from the bare bones of our genes and brains.We stand on the brink of a tectonic shift in our understanding of ourselves that will witness the rediscovery of the central premise of Western philosophy that there is 'more than we can know'. Lucid, compelling and utterly engaging, ‘Why Us?’ offers a convincing and provocative vision of the new science of being human.

    

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Darwin’s theory has withstood 150 years of scientific scrutiny, and today it not only explains the origin and design of living things, but highlights the importance of a scientific understanding in our culture and in our lives.Recently the movement known as “Intelligent Design” has attracted the attention of journalists, educators, and legislators. The scientific community is puzzled and saddened by this trend–not only because it distorts modern biology, but also because it diverts people from the truly fascinating ideas emerging from the real science of evolution. Here, join fifteen of our preeminent thinkers whose clear, accessible, and passionate essays reveal the fact and power of Darwin’s theory, and the beauty of the scientific quest to understand our world.

    The planet most like ours, it has still been thought impossible to reach, let alone explore and inhabit.Now with the advent of a revolutionary new plan, all this has changed. leading space exploration authority Robert Zubrin has crafted a daring new blueprint, Mars Direct, presented here with illustrations, photographs, and engaging anecdotes.The Case for Mars is not a vision for the far future or one that will cost us impossible billions. It explains step-by-step how we can use present-day technology to send humans to Mars within ten years; actually produce fuel and oxygen on the planet's surface with Martian natural resources; how we can build bases and settlements; and how we can one day "terraform" Mars--a process that can alter the atmosphere of planets and pave the way for sustainable life.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    Yet it is so ravaged by human activity that half its species could be gone by the end of the present century. These two contrasting truths—unexpected magnificence and underestimated peril—have become compellingly clear during the past two decades of research on biological diversity.In this dazzlingly intelligent and ultimately hopeful book, Wilson describes what treasures of the natural world we are about to lose forever—in many cases animals, insects, and plants we have only just discovered, and whose potential to nourish us, protect us, and cure our illnesses is immeasurable—and what we can do to save them. In the process, he explores the ethical and religious bases of the conservation movement and deflates the myth that environmental policy is antithetical to economic growth by illustrating how new methods of conservation can ensure long-term economic well-being.The Future of Life is a magisterial accomplishment: both a moving description of our biosphere and a guidebook for the protection of all its species, including humankind.

    The End of Animal Farming pushes this conversation forward by outlining a strategic roadmap to a humane, ethical, and efficient food system in which slaughterhouses are obsolete—where the tastes of even the most die-hard meat eater are satisfied by innovative food technologies like cultured meats and plant-based protein. Social scientist Jacy Reese Anthis analyzes the social forces leading us toward the downfall of animal agriculture, the technology making this change possible for the meat-hungry public, and the activism driving consumer demand for plant-based and cultured foods.Reese contextualizes the issue of factory farming—the inhumane system of industrial farming that 95 percent of farmed animals endure—as part of humanity's expanding moral circle. Humanity increasingly treats nonhuman animals, from household pets to orca whales, with respect and kindness, and Reese argues that farmed animals are the next step. Reese applies an analytical lens of "effective altruism," the burgeoning philosophy of using evidence-based research to maximize one's positive impact in the world, in order to better understand which strategies can help expand the moral circle now and in the future.The End of Animal Farming is not a scolding treatise or a prescription for an ascetic diet. Reese invites readers—vegan and non-vegan—to consider one of the most important and transformational social movements of the coming decades.

    After ten years of attending events like the giant Creation Mega-Conference in Lynchburg, Virginia, and visiting sites like the Creation Museum in Petersburg, Kentucky, and after hundreds of surprisingly friendly conversations with creationists of varying stripes, he has emerged with a story to tell, a story that goes well beyond the usual stereotypes of Bible-thumping fanatics railing against coldly rational scientists. Through anecdotes, personalreflections, and scientific and philosophical discussion, Rosenhouse presents a more down-to-earth picture of modern creationism and the people who espouse it. He is neither polemical nor insulting, but he does not pull punches when he spots an error in the logical or scientific reasoning ofcreationists, especially when they wander into his own field, mathematics. Along the way, he also tells the story of his own nonbeliever's attempt to understand a major aspect of American religion. Forced to wrestle with his views about God and evolution, Rosenhouse found himself drawn into a newworld of ideas previously unknown to him, arriving at a sharper understanding of the reality of science-versus-religion disputes, and how these debates look to those beyond the ivory tower.A personal memoir of one scientist's attempt to come to grips with this controversy-by immersing himself in the culture of the anti-evolutionists-Among the Creationists is a fair, fresh, and insightful account of the modern American debate over Darwinism.

    We now understand more about aging—and how to prevent and reverse it—than ever before.In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility.Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.On first examination, aging appears inevitable and straight-forward. Everything, after all, from mountains and galaxies, to plants and animals, ages, doesn’t it? Not exactly. With deeper consideration, aging turns out to be complex, and surprising questions emerge:Is aging something that happens within our cells or in the organism as a whole?Why do some cells age every time they reproduce, while others can reproduce indefinitely, without signs of aging?How close are we to being able to dramatically extend life-spans and cure age-related diseases such as Alzheimer’s, dementia, and strokes?Instead of the common idea that “we accumulate damage, therefore we age,” the reality is the opposite: our cells age and so we begin to accumulate damage. The latest research shows so-called “ageless” cells contain “telomerase”—an enzyme that maintains telomeres and adds back segments lost during replication. Essentially, it is the telomere that controls how well our cells repair themselves over time.The Telomerase Revolution explains simply how we came to understand the ways aging and age-related diseases work, what we can do about them now, what we will be able to do to cure and prevent these diseases—and why we are now on the brink of a revolution in human medicine.

    

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    Recent research in the neurosciences and neurocardiology identifies the four neural centers of our brain and indicates that a fifth such center is located in the heart. This research reveals that the evolutionary structure of our brain and its dynamic interactions with our heart are designed by nature to reach beyond our current evolutionary capacities. We are quite literally, made to transcend. Pearce explores how this biological imperative drives our life into ever-greater realms of being--even as the cultural imperative of social conformity and behavior counters this genetic heritage, blocks our transcendent capacities, and breeds violence in all its forms. The conflict between religion and spirit is an important part of this struggle. But each of us may overthrow these cultural imperatives to reach unconflicted behavior, wherein heart and mind-brain resonate in synchronicity, opening us to levels of possibility beyond the ordinary.

    In Evolution Impossible, Dr. John Ashton uses discoveries in genetics, biochemistry, geology, radiometric dating, and other scientific disciplines to explain why the theory of evolution is a myth. Regardless of your level of scientific education, you will finish this book able to cite 12 reasons why evolution cannot explain the origin of life.