Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    Includes special bonus material!Sharing never-before-heard stories ranging from their struggles with depression, eating disorders, and addiction, Karen and Georgia irreverently recount their biggest mistakes and deepest fears, reflecting on the formative life events that shaped them into two of the most followed voices in the nation.In Stay Sexy & Don’t Get Murdered, Karen and Georgia focus on the importance of self-advocating and valuing personal safety over being ‘nice’ or ‘helpful.’ They delve into their own pasts, true crime stories, and beyond to discuss meaningful cultural and societal issues with fierce empathy and unapologetic frankness.

    In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    With soaring prose that celebrates a resurgent American Midwest, Shortest Way Home narrates the heroic transformation of a “dying city” (Newsweek) into nothing less than a shining model of urban reinvention.Interweaving two narratives—that of a young man coming of age and a town regaining its economic vitality—Buttigieg recounts growing up in a Rust Belt city, amid decayed factory buildings and the steady soundtrack of rumbling freight trains passing through on their long journey to Chicagoland. Inspired by John F. Kennedy’s legacy, Buttigieg first left northern Indiana for red-bricked Harvard and then studied at Oxford as a Rhodes Scholar, before joining McKinsey, where he trained as a consultant—becoming, of all things, an expert in grocery pricing. Then, Buttigieg defied the expectations that came with his pedigree, choosing to return home to Indiana and responding to the ultimate challenge of how to revive a once-great industrial city and help steer its future in the twenty-first century.Elected at twenty-nine as the nation’s youngest mayor, Pete Buttigieg immediately recognized that “great cities, and even great nations, are built through attention to the everyday.” As Shortest Way Home recalls, the challenges were daunting—whether confronting gun violence, renaming a street in honor of Martin Luther King Jr., or attracting tech companies to a city that had appealed more to junk bond scavengers than serious investors. None of this is underscored more than Buttigieg’s audacious campaign to reclaim 1,000 houses, many of them abandoned, in 1,000 days and then, even as a sitting mayor, deploying to serve in Afghanistan as a Navy officer. Yet the most personal challenge still awaited Buttigieg, who came out in a South Bend Tribune editorial, just before being reelected with 78 percent of the vote, and then finding Chasten Glezman, a middle-school teacher, who would become his partner for life.While Washington reels with scandal, Shortest Way Home, with its graceful, often humorous, language, challenges our perception of the typical American politician. In chronicling two once-unthinkable stories—that of an Afghanistan veteran who came out and found love and acceptance, all while in office, and that of a revitalized Rust Belt city no longer regarded as “flyover country”—Buttigieg provides a new vision for America’s shortest way home.

    She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone.It started with an itch—first on her feet, then up her legs, like a thousand invisible mosquito bites. Next came the exhaustion, and the six-hour naps that only deepened her fatigue. Then a trip to the doctor and, a few weeks shy of her twenty-third birthday, a diagnosis: leukemia, with a 35 percent chance of survival. Just like that, the life she had imagined for herself had gone up in flames. By the time Jaouad flew home to New York, she had lost her job, her apartment, and her independence. She would spend much of the next four years in a hospital bed, fighting for her life and chronicling the saga in a column for The New York Times.When Jaouad finally walked out of the cancer ward—after three and a half years of chemo, a clinical trial, and a bone marrow transplant—she was, according to the doctors, cured. But as she would soon learn, a cure is not where the work of healing ends; it’s where it begins. She had spent the past 1,500 days in desperate pursuit of one goal—to survive. And now that she’d done so, she realized that she had no idea how to live.How would she reenter the world and live again? How could she reclaim what had been lost? Jaouad embarked—with her new best friend, Oscar, a scruffy terrier mutt—on a 100-day, 15,000-mile road trip across the country. She set out to meet some of the strangers who had written to her during her years in the hospital: a teenage girl in Florida also recovering from cancer; a teacher in California grieving the death of her son; a death-row inmate in Texas who’d spent his own years confined to a room. What she learned on this trip is that the divide between sick and well is porous, that the vast majority of us will travel back and forth between these realms throughout our lives. Between Two Kingdoms is a profound chronicle of survivorship and a fierce, tender, and inspiring exploration of what it means to begin again.

    With a slow chill that intensifies with each heart-pounding page, Rule describes her dawning awareness that Ted Bundy, her sensitive coworker on a crisis hotline, was one of the most prolific serial killers in America. He would confess to killing at least thirty-six young women from coast to coast, and was eventually executed for three of those cases. Drawing from their correspondence that endured until shortly before Bundy's death, and striking a seamless balance between her deeply personal perspective and her role as a crime reporter on the hunt for a savage serial killer -- the brilliant and charismatic Bundy, the man she thought she knew -- Rule changed the course of true-crime literature with this unforgettable chronicle.

    Just as Nicks (and Lindsay Buckingham) gave Fleetwood Mac the shot of adrenaline they needed to become real rock stars--according to Christine McVie--Gold Dust Woman is vibrant with stories and with a life lived large and hard: ●How Nicks and Buckingham were asked to join Fleetwood Mac and how they turned the band into stars ●The affairs that informed Nicks' greatest songs ●Her relationships with the Eagles' Don Henley and Joe Walsh, and with Fleetwood himself ●Why Nicks married her best friend's widower ●Her dependency on cocaine, drinking and pot, but how it was a decade-long addiction to Klonopin that almost killed her ●Nicks' successful solo career that has her still performing in venues like Madison Square Garden ●The cult of Nicks and its extension to chart-toppers like Taylor Swift and the Dixie Chicks

    The colorful characters she meets while delivering babies all over London--from the plucky, warm-hearted nuns with whom she lives to the woman with twenty-four children who can't speak English to the prostitutes and dockers of the city's seedier side--illuminate a fascinating time in history. Beautifully written and utterly moving, The Midwife will touch the hearts of anyone who is, and everyone who has, a mother.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    When the bird refuses to leave Tom's side, the young teacher has no choice but to take it with him and look after it. This is their story.

    Her family dated back to the group's origins in the first half of the nineteenth century, and her father was a high-ranking minister. However, as an intelligent, inquiring child, Stott was always asking dangerous questions and so, it turns out, was her father, who was also full of doubt. When a sex scandal tore the Exclusive Brethren apart in 1970, her father pulled the family out of the cult. But its impact on their lives shaped everything before and all that was to come.The Iron Room (named for the windowless meeting houses made of corrugated iron where the Brethren would worship) is Stott's attempt to understand and even forgive her father: a brilliant, charismatic, difficult, and at times cruel man who nonetheless inspired his daughter with his love of literature, film, and art and with his passion for life.

    Now, with this collection of original essays, he reminds us of the principles upon which the United States was founded. Looking at the freedoms that define us, from the vote to the press; the values that have transformed us, from empathy to inclusion to service; the institutions that sustain us, such as public education; and the traits that helped form our young country, such as the audacity to take on daunting challenges in science and medicine, Rather brings to bear his decades of experience on the frontlines of the world’s biggest stories. As a living witness to historical change, he offers up an intimate view of history, tracing where we have been in order to help us chart a way forward and heal our bitter divisions. With a fundamental sense of hope, What Unites Us is the book to inspire conversation and listening, and to remind us all how we are, finally, one.