Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    Shubin describes how over the last half-century, scientists have been able to explore how genetic recipes build bodies during embryological development--how these inventions and adaptations occur in a nonprogressive manner in different contexts, at different speeds. Paleontology has been transformed over the last 50 years by tools and techniques of molecular biology--and it is that revolution in our understanding of the evolution of life that Shubin traces here. Each of us is a mosaic of precursors that came about at different times and places, with deep rooted connections across species that Darwin, for all he understood, could never even have imagined.

    These areas of knowledge have converged into a modern theory of epidemiology that has been slow to penetrate into textbooks, particularly at the introductory level. Epidemiology: An Introduction closes the gap. It begins with a brief, lucid discussion of causal thinking and causal inference and then takes the reader through the elements of epidemiology, focusing on the measures of disease occurrence and causal effects. With these building blocks in place, the reader learns how to design, analyze and interpret problems that epidemiologists face, including confounding, the role of chance, and the exploration of interactions. All these topics are layered on the foundation of basic principles presented in simple language, with numerous examples and questions for further thought.

    Adam Brochert, MD-who scored in the 99th percentile on the Step 2 USMLE-and Theodore X. O'Connell, MD-author of several review and clinical reference books-present essential questions and answers covering the important concepts you need to know to score well on the USMLE Step 2 exam: key conditions you will be expected to recognize, all specialty and subspecialty topics, and necessary clinical concepts.Learn the most important questions and answers with the proven format of the highly acclaimed Secrets Series.Master all specialty and subspecialty topics covered on Step 2.Identify key facts and secrets using the Top 100 Secrets chapter.Review material quickly and easily thanks to bulleted lists, algorithms, and illustrations.Apply the pearls, tips, memory aids, and secrets from well-known and highly popular authors, Adam Brochert, MD and Theodore X. O'Connell, MD. Find information quickly with a second color highlighting chapter and section titles, legends, bullets and icons, and key terms.Consult the book wherever you go thanks to the portable size that fits in your lab coat pocket.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Along the tidal rivers of Malaysia, thousands of fireflies congregate and flash in unison; the moon spins in perfect resonance with its orbit around the earth; our hearts depend on the synchronous firing of ten thousand pacemaker cells. While the forces that synchronize the flashing of fireflies may seem to have nothing to do with our heart cells, there is in fact a deep connection. Synchrony is a science in its infancy, and Strogatz is a pioneer in this new frontier in which mathematicians and physicists attempt to pinpoint just how spontaneous order emerges from chaos. From underground caves in Texas where a French scientist spent six months alone tracking his sleep-wake cycle, to the home of a Dutch physicist who in 1665 discovered two of his pendulum clocks swinging in perfect time, this fascinating book spans disciplines, continents, and centuries. Engagingly written for readers of books such as Chaos and The Elegant Universe, Sync is a tour-de-force of nonfiction writing.

    The authors capture students' interest with up-to-date coverage of cutting edge topics and research. This text will help students connect the science of genetics to the issues of today through interesting and thought-provoking applications. The sixth edition boasts the next generation of media integration including Gen CD-X (student CD-ROM and Companion Website).

     A powerful true story revealing a remarkable relationship between a dying son - and a mother that refuses to let him go. At the age of 10, Deryn was diagnosed with Leukaemia. Then 18 months later he developed another rare form of cancer called Langerhan’s cell sarcoma. Only five other people in the world have it. He is the youngest of them all and the only person in the world known to be fighting it alongside another cancer, making him one in seven billion. Told there was no hope of survival, after four years of intensive treatment, exhausted by his fight and with just days left to live, Deryn planned his own funeral. But, Deryn’s desperate mother, Callie would not let him give in. Battling medical errors, impossible odds and years of hardship as the cancer consumed his body and their world, they looked for more answers. After making some startling discoveries and taking massive chances - something began to change… Would their lives as a family ever be the same again?

    Touching on such diverse subspecialties as genetics, pharmacology, neurology, sexology, and immunology, Pickover intersperses “obvious” historical milestones--the Hippocratic Oath, general anesthesia, the Human Genome Project--with unexpected and intriguing topics like “truth serum,” the use of cocaine in eye surgery, and face transplants.

    Shapiro's Evolution: A View from the 21st Century proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents a compelling alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and mobile genetic elements, and points toward an emerging synthesis of physical, information, and biological sciences.

    But they're in store for a special lesson. Using Dr. Moro's virtual reality machine to travel inside the human body, they'll get a close-up look at the fascinating world of molecular biology.Join them in The Manga Guide to Molecular Biology, and learn all about DNA, RNA, proteins, amino acids, and more. Along the way, you'll see chemical reactions first-hand and meet entertaining characters like Enzyme Man and Drinkzilla, who show how the liver metabolizes alcohol.Together with Ami and Rin, you'll learn all about: -The organelles and proteins inside cells, and how they support cellular functions-The processes of transcription and translation, and your genes' role in synthesizing proteins-The pieces that make up our genetic code, like nucleotides, codons, introns, and exons-The processes of DNA replication, mitosis and cytokinesis-Genetic technology like transduction and cloning, and the role of molecular biology in medicineWhether you need a molecular biology refresher or you're just fascinated by the science of life, The Manga Guide to Molecular Biology will give you a uniquely fun and informative introduction.

    Everything about our existence—movement and memory, imagination and reproduction, birth and, ultimately, death—is governed by our cells. They are the basis of all life in the universe, from the tiniest bacteria to the most complex animals. In the tradition of the classic Lives of a Cell, but with the benefit of the latest research, internationally acclaimed embryologist Lewis Wolpert demonstrates how human life derives from a single cell and then grows into a body, an incredibly complex society made up of billions of them. When we age, our cells cannot repair the damage they have undergone; when we get ill, it is because cells are so damaged they stop working and die. Wolpert examines the science behind topics that are much discussed but rarely understood—stem cell research, cloning, DNA, mutating cancer cells—and explains how all life evolved from just one cell. Lively and passionate, this is an accessible guide to understanding the human body and life itself. .

    A new foreword by Kip Thorne, the current Richard Feynman Professor of Theoretical Physics at Caltech, discusses the relevance of the new edition to today's readers. This boxed set also includes Feynman's new Tips on Physics—the four previously unpublished lectures that Feynman gave to students preparing for exams at the end of his course. Thus, this 4-volume set is the complete and definitive edition of The Feynman Lectures on Physics. Packaged in a specially designed slipcase, this 4-volume set provides the ultimate legacy of Feynman's extraordinary contribution to students, teachers, researches, and lay readers around the world.

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.