She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    Cancer does not have me.' Sophie Sabbage was diagnosed with late stage 'incurable' lung cancer in October 2014. She was 48 years old, happily married with a 4-year-old daughter. Since that day - when doctors told Sophie that her prognosis was poor - she has been on a remarkable journey of healing and transformation that has reshaped her vocation as well as changed her life for the better. The Cancer Whisperer chronicles Sophie's extraordinary relationship with cancer and the methods that she has used for dealing with fear, anger, denial and grief. The essence of 'cancer whispering' was born of Sophie's determination to take cancer off the battlefield and into the classroom. Instead of going to war with it, Sophie has chosen to listen to it, learn from it and choose her own response to it.Sophie offers a radically different way of relating to this disease both mentally and practically: she shares the research she has done, the treatments she has chosen, the diet she follows and the resources that she feels have made the biggest differences in the hope that they will help others cut through the mass of information out there.Sophie says: 'This book is for the cancer patient who wants to remain a dignified, empowered human being even when your doctors and diagnosis are scaring the hell out of you. It is also for the cancer patient who has a hunch that there is something for them to learn, gain or even be transformed by - if they just knew how to relate to this disease differently to the way most of society does. It is for the cancer patient, perhaps any patient.'

    Margaret Combs shows how her Southern Baptist family coped with the lived reality of autism in an era of ignorance and shame, the 1950s through the 1970s, and shares her own tragedy and anguish of being torn between helping her brother and yearning for her own life. Like many siblings of disabled children, young Margaret drives herself to excel in order to make up for her family’s sorrow and ultimately flees her family for what she hopes is a “normal” life.Hazard is also a story of indelible bonds between siblings: the one between Combs and her sister, and the deep and rueful one she has with her disabled brother; how he and she were buddies; and how fervently she wanted to make him whole. Initially fueled by a wish that her brother had never been born, the author eventually arrives in a deeper place of gratitude for this same brother, whom she loves and who loves her in return.

    Richly textured with bits of her own childhood and married life with her husband, John Gregory Dunne, and daughter, Quintana Roo, this book by Joan Didion examines her thoughts, fears, and doubts regarding having children, illness, and growing old.  Blue Nights opens on July 26, 2010, as Didion thinks back to Quintana’s wedding in New York seven years before. Today would be her wedding anniversary. This fact triggers vivid snapshots of Quintana’s childhood—in Malibu, in Brentwood, at school in Holmby Hills. Reflecting on her daughter but also on her role as a parent, Didion asks the candid questions any parent might about how she feels she failed either because cues were not taken or perhaps displaced. “How could I have missed what was clearly there to be seen?” Finally, perhaps we all remain unknown to each other. Seamlessly woven in are incidents Didion sees as underscoring her own age, something she finds hard to acknowledge, much less accept.  Blue Nights—the long, light evening hours that signal the summer solstice, “the opposite of the dying of the brightness, but also its warning”—like The Year of Magical Thinking before it, is an iconic book of incisive and electric honesty, haunting and profoundly moving.

    But as you will see in Playing God, earning an M.D. is just the first step to becoming a real physician.In this page-turning, thrilling, and moving memoir, Dr. Anthony Youn reveals that the true metamorphosis from student to doctor occurs not in medical school but in the formative years of residency training and early practice. It is only through actually saving and losing patients, taking on the medical establishment, wrestling with financial and emotional survival, and fighting for patients’ lives that a young doctor becomes a mature and competent physician.Dr. Youn takes you from the operating rooms of a university surgery residency program to the gleaming offices of top Beverly Hills plastic surgeons to opening the doors of his empty clinic as a new doctor with no money, no patients, and mountains of debt. Playing God leaves you with an unexpected answer to that profound question: “What does it mean to be a doctor?” In Playing God, you will take a journey through the world of surgery, hospitals, and the practice of medicine unlike any that you have traveled before.

    A lanky kid from Plano, Texas, is raised by a feisty, single parent who sacrifices for her son, who becomes one of our country's greatest athletes. Given that background, it is understandable why Armstrong was able to channel his boundless energy toward athletic endeavors. By his senior year in high school, he was already a professional triathlete and was training with the U.S. Olympic cycling developmental team. In 1993, Armstrong secured a position in the ranks of world-class cyclists by winning the World Championship and a Tour de France stage, but in 1996, he was diagnosed with testicular cancer. Armstrong entered an unknown battlefield and challenged it as if climbing through the Alps: aggressive yet tactical. He beat the cancer and proceeded to stun all the pundits by winning the 1999 Tour de France. In this memoir, Armstrong covers his early years swiftly with a blunt matter-of-factness, but the main focus is on his battle with cancer. Readers will respond to the inspirational recovery story, and they will appreciate the behind-the-scenes cycling information. After he won the Tour, his mother was quoted as saying that her son's whole life has been a fight against the odds; we see here that she was not exaggerating. Brenda Barrera

    offers his profound insights into the greatest challenge we face: confronting our own mortality. "Shortly after the cancer had been diagnosed I began writing letters to the members of my immediate family, to relatives and to lifelong friends. The following book will consist mostly of those letters. They will invite you into my most intimate dancing with the cancer, even as that partner and I have over the last two years swung each other around the tiled floors of ballrooms and bathrooms. Dizzy still, and day by day, I sat and wrote: This is what I'm feeling right now. This is what I think...." From afternoon to afternoon of radiation, Wangerin wrote about confronting his mortality, about living with the messiness of undone tasks and bodily weakness. He wrote about the medical procedures he endured, the wild mood swings that unbalanced his days, and the fragilities and strengths of the relationships that surrounded him. Letters from the Land of Cancer is made up of these writings. Cadenced within the letters are Wangerin's eloquent meditations derived from his pastoral experiences with the faithful passage of death to life. Seldom has the great adventure of life and death been as beautifully presented as it is in this testimony to faith, love, and the shocking reality of hope.

    As she faced life without the husband she called her “magic man,” Jai learned to make herself a priority to create a new life of hope and happiness—as she puts it, to “feel a spark of my own magic beginning to flicker.”     Dream New Dreams is a powerful story of grief, healing, and newfound independence. With advice artfully woven into an intimate, beautifully written narrative, Jai’s story will inspire not only the legions of readers who made The Last Lecture a bestseller, but also those who are embarking on a journey of loss and renewal themselves.

    Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself. By the time the results of his groundbreaking experiments were published, Dr. Baird had been institutionalized multiple times, his medical license revoked, and his wife and daughters estranged. He later received a lobotomy and died from a consequent seizure, his research incomplete, his achievements unrecognized.Mimi Baird grew up never fully knowing this story, as her family went silent about the father who had been absent for most of her childhood. Decades later, a string of extraordinary coincidences led to the recovery of a manuscript which Dr. Baird had worked on throughout his brutal institutionalization, confinement, and escape. This remarkable document, reflecting periods of both manic exhilaration and clear-headed health, presents a startling portrait of a man who was a uniquely astute observer of his own condition, struggling with a disease for which there was no cure, racing against time to unlock the key to treatment before his illness became impossible to manage.Fifty years after being told her father would forever be “ill” and “away,” Mimi Baird set off on a quest to piece together the memoir and the man. In time her fingers became stained with the lead of the pencil he had used to write his manuscript, as she devoted herself to understanding who he was, why he disappeared, and what legacy she had inherited. The result of his extraordinary record and her journey to bring his name to light is He Wanted the Moon, an unforgettable testament to the reaches of the mind and the redeeming power of a determined heart.Soon to be a major motion picture, from Brad Pitt and Tony Kushner

    And it’s a question that women everywhere are asking themselves as we seek to balance all of our roles, responsibilities, and opportunities.So, how do we do it? Working since the age of 5, Candace has been in a balancing act for nearly her entire life. She is the first to tell you that there is no miracle formula for perfect execution in every area of your life, but there definitely are some lessons to be learned, lessons that come to life in Candace's story. Come along and dig into Candace’s story from her start in commercials, the balance-necessitating years on Full House, to adding on the roles of wife and mom while also returning to Hollywood. Insightful, funny, and poignant, Candace’s story will help you balance it all.

    Paul Seward leads us in his memoir through suspenseful diagnoses and explorations of anatomy. By his side, we learn to distinguish nursemaid's elbow from a true broken arm. We learn how our breathing and swallowing mechanisms resemble a practical joke.But when a baby’s heart stops and a young doctor forgets what to do, the situation is far from funny. Within the conditions of great stress and rapid decision-making that are routine in the ER, Dr. Seward shows us that physicians must be more than technicians of the body; they must be restorers of the human. Whether it is comforting anxious family or subjecting a distressed patient to tough procedures—resulting, once, in a patient’s punching our doctor—on every shift, a physician learns the difficult work of caring for strangers.Yet this is a physician who rejects doctor-as-god narratives. He highlights the essential role of nurses and other colleagues, including a pharmacist whose story is hard to forget. Throughout Patient Care, Dr. Seward reflects on how a life in medicine tests what it means to put ethics into practice.

    "I was born in the month of July, and my horoscope sign is a disease (Cancer). The symbol for Cancer? A crab (the sexually transmitted critter). Not only that, my parents named me Shawn Timothy Decker, which makes my initials S.T.D. Shawn Decker isn't quite the all-American boy. Sure, he gets caught shoplifting copies of Penthouse, is crazy about pro wrestling, especially "The Nature Boy" Ric Flair, and never has a problem getting dates. But he's also a hemophiliac who discovers, at age eleven, that he has contracted HIV from tainted blood products. Instead of becoming self-pitying and dying (as first predicted), Shawn develops a twisted sense of humor, meets Depeche Mode through the Make-A-Wish Foundation, and writes on blogs and in Poz magazine about what it's like being hetero and HIV-positive in rural Virginia. He also turns to gay men for advice on dating women and, almost twenty years after getting HIV, marries Gwenn Barringer, who is HIV-negative and a former competitor for the title of Miss Virginia. Together Shawn and Gwenn travel the country, speaking to high school and college kids about how to live and love with HIV (and how to avoid getting it).

    In this dazzling collection of essays, skillfully constructed and brimming with emotion, she shares her thoughts on the joys and vagaries of modern-day womanhood and motherhood, introduces the not-quite-typical family that made her who she is, and persuasively argues that lowbrow pop culture is the perfect lens through which to understand human nature.Whether she’s extolling the virtues of eating in bed, processing the humiliation over her father’s late in life perm, or exploring her pathological need to be liked, Casey is witty, candid, and full of poignant and funny surprises. Humorous dives into her obsessions and areas of personal expertise—Scientology and self-help, nice guys, reality television shows—are matched by touching meditations on female friendship, grief, motherhood, and identity. Reading The Wreckage of My Presence is like spending time with a close friend—a deeply passionate, full-tilt, joyous, excessive, compulsive, shameless, hungry-for-it-all, loyal, cheerleading friend. A friend who is ready for any big feeling that comes her way and isn’t afraid to embrace it.Bed person --The wreckage of my presence --To all the boys I loved before --Cool girl --A saber story --Send in the clowns --Flyentology --Hide your phones --Expect a miracle --Hiked out --The BBQ --Tears of a clown --Happy endings --My husband's just not that into me; or Afrin: a love story --Grandpa's pretty girl --It doesn't do --What dis --Open-door policy --Mother's day --People don't know how to act --Gimme some sugar; or, the wreckage of my presence redux

    Saag, MD, an internationally known expert on the virus that causes AIDS, but the book is more than a memoir: through his story, Dr. Saag also shines a light on the dysfunctional US healthcare system, proposing optimistic yet realistic remedies drawn from his distinguished medical career.Mike Saag began his medical residency in 1981, within days of the Centers for Disease Control’s first report of a mysterious “gay cancer” killing young men. Soon, the young doctor’s career was yoked to the epidemic. His life’s work became turning the most deadly virus in human history into a chronic, manageable disease.In the lab at the University of Alabama at Birmingham, Dr. Saag and colleagues made seminal early discoveries about the elusive virus. And at the AIDS clinic he founded, Dr. Saag met people whose fight against a virtual death sentence touched his heart and inspired him to work even harder. As his career stretched across three decades, Dr. Saag found himself battling another foe, this one almost as pernicious as AIDS itself: a broken healthcare system shaped more by politicians, insurers, and lobbyists than by patients’ needs.Positive is Dr. Saag’s tribute to the unforgettable patients he has known and an urgent call to create a comprehensive, compassionate, accessible healthcare system in the name of those we can save today.