Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate osteonecrosis, the oral complications associated with methamphetamine abuse, solitary fibrous tumors, gene mutation, and plasminogen deficiency.Over 1,300 clinical photos and radiographs, most in full color, facilitate identification and classification of lesions.Current concepts of pathogenesis and disease management help you understand the diseases that affect the oral and maxillofacial structures, formulate an accurate diagnosis, and institute proper treatment.Each chapter is logically organized by body system or disease group, enabling you to easily identify a specific condition.A comprehensive appendix of differential diagnosis among oral and maxillofacial disease processes helps you rule out invalid diagnoses.The bibliography divided by topic presented at the end of each chapter enables you to pursue supplemental literature.Highly accomplished authors and contributors with a broad range of clinical and classroom teaching experience provide well-balanced coverage of the entire subject.Chapter outlines at the beginning of each chapter allow immediate access to specific topics.Over 200 new illustrations have been added to this popular, visual reference.A new section on bisphosphonate-associated osteonecrosis thoroughly explores and illustrates this recently identified complication resulting from medications used to prevent bone loss in patients with multiple myeloma, metastatic tumors, and osteoporosis.A new section about the oral complications of methamphetamine abuse details characteristic oral manifestations such as meth mouth caries" and factitial injuries.Expanded coverage of oral piercings, intraoral tattoos, and other body modifications includes unusual entities such as tongue splitting and charm needles.A new section on transient lingual papillitis sheds light on this common cause of transitory tongue irritation.A new section on solitary fibrous tumors familiarizes you with this popular designation for certain benign fibrous neoplasms.A new section on hypoplasminogenemia (ligneous conjunctivitis), or plasminogen deficiency, includes images from a patient case that illustrate the characteristic gingival lesions associated with this rare but fascinating systemic condition.A new section on hereditary mucoepithelial dysplasia describes the characteristic oral manifestations that can lead you to accurately diagnose this condition, potentially preventing a woman with this disorder from having cytologically unusual cells misdiagnosed as carcinoma on her cervical PAP smears.A new section discusses the clinical and microscopic features of chronic ulcerative stomatitis, an immune-mediated condition of the oral mucosa that presents with erosive lesions and is often mistaken for lichen planus.The chapter on Forensic Dentistry has been thoroughly revised and updated by leading forensic odontology author, Dr. Edward Herschaft, to include the latest information on this fascinating topic.Several chapters have been updated to include the most current knowledge of specific gene mutations associated with hereditary oral disorders.

    Now comes a gripping account of the doctors and scientists fighting to protect us, an urgent wake-up call about the future of emerging viruses—from the #1 bestselling author of The Hot Zone, soon to be a National Geographic original miniseries.This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents.In this taut and suspenseful medical drama, Richard Preston deeply chronicles the outbreak, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time.Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before.The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.

    The Topics And Chapters Are Organized In A Sequence That Is Easy To Follow, Beginning With The Most Familiar -- Structure -- And Proceeding To The Less Familiar -- Metabolism -- Then Finishing With Those Topics That Are Probably The Least Familiar To Most Beginning Students -- Genetics, Evolution, The Diversity Of Organisms, And Ecology.

    Her story and others like it show that humans are not the only species with the capacity for love, hate, fear, shame, guilt, joy, disgust, and empathy, and open our hearts and minds to the many ways in which humans and other animals are connected. “Through colorful stories and riveting prose, de Waal firmly puts to rest the stubborn notion that humans alone in the animal kingdom experience a broad array of emotions.” — Barbara J. King, NPR“De Waal’s eye- opening observations argue for better treatment and greater appreciation of animals, even as he ensures that you’ll never look at them—or yourself—the same way again.” — People

    This third edition, entitled Medical Parasitology in the Philippines, contains an updated version of the global, regional, and national status of parasitic diseases, with particular focus on the Philippines, as well as Southeast Asia and the Western Pacific Regions. In this latest edition, the life cycles developed by the United States Centers for Disease Control and Prevention are utilized, and as in the other earlier editions, Bench Aids developed by the World Health Organization are included for reference purposes. For the first time, relevant policies and guidelines from the Department of Health are listed for further guidance of the readers. This edition also includes new sections that address recent developments in the field and nationally relevant global interests such as neglected tropical diseases, preventive chemotherapy, emporiatrics, and laboratory biosafety.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    In The Anatomy of Violence, Raine dissects the criminal mind with a fascinating, readable, and far-reaching scientific journey into the body of evidence that reveals the brain to be a key culprit in crime causation.  Raine documents from genetic research that the seeds of sin are sown early in life, giving rise to abnormal physiological functioning that cultivates crime. Drawing on classical case studies of well-known killers in history—including Richard Speck, Ted Kaczynski, and Henry Lee Lucas—Raine illustrates how impairments to brain areas controlling our ability to experience fear, make good decisions, and feel guilt predispose us to violence. He contends that killers can actually be coldhearted: something as simple as a low resting heart rate can give rise to violence. But arguing that biology is not destiny, he also sketches out provocative new biosocial treatment approaches that can change the brain and prevent violence.  Finally, Raine tackles the thorny legal and ethical dilemmas posed by his research, visualizing a futuristic brave new world where our increasing ability to identify violent offenders early in life might shape crime-prevention policies, for good and bad. Will we sacrifice our notions of privacy and civil rights to identify children as potential killers in the hopes of helping both offenders and victims? How should we punish individuals with little to no control over their violent behavior? And should parenting require a license? The Anatomy of Violence offers a revolutionary appraisal of our understanding of criminal offending, while also raising provocative questions that challenge our core human values of free will, responsibility, and punishment.From the Hardcover edition.

    

    It made him laugh." Cindy McCain "This book is funny, moving and inspirational. I read some of it and had to get him on my radio show." Christian O'Connell, Absolute Radio Breakfast Show DJ "So honest, uninhibited, down-to-earth and readable despite the difficult subject. The best non-fiction book I have read in a very long time.....and I strongly recommend it." Peter J "Hilarious and moving in equal measures. What a brave man!" David Reuben "Adam Blain manages to be funny, poignant and inspiring describing with heart breaking honesty his journey so far, beginning with a diagnosis no one ever wants to face." RG A must-read memoir about coping with cancer Description Adam is a middle aged father of three. Completely out of the blue, and for no reason other than sheer dumb chance, he was diagnosed with a rare and aggressive brain tumour. Adam has endured radiotherapy and chemotherapy which were preceded by major brain surgery to remove the tumour - helpfully described by his surgeon as being the size and shape of a pear. Using the blackest of humour, this book charts Adam's journey from normality to having a disease regularly described as a “death sentence”. How will he cope with the treatment? How will his relationship with family and friends be affected? Most important of all, how will his hair come through this? Quite simply, it is the funniest book so far this year about brain cancer. Warning - this book is intended for mature audiences due to the subject matter and use of strong language.

    Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.

    William Maples can deduce the age, gender, and ethnicity of a murder victim, the manner in which the person was dispatched, and, ultimately, the identity of the killer.  In Dead Men Do Tell Tales, Dr. Maples revisits his strangest, most interesting, and most horrific investigations, from the baffling cases of conquistador Francisco Pizarro and Vietnam MIAs to the mysterious deaths of President Zachary Taylor and the family of Czar Nicholas II.

    Yet for all our advanced scientific knowledge, only one human disease – smallpox – has ever been eradicated globally.In recent years, outbreaks of Ebola and Zika have provided vivid examples of how difficult it is to contain an infection once it strikes, and the panic that a rapidly spreading epidemic can ignite. But while we chase the diseases we are already aware of, new ones are constantly emerging, initiating a new race to identify them. At the same time, antimicrobial resistance is harnessing infections that we once knew how to control, enabling them to thrive once more. Meera Senthilingam presents a timely look at humanity’s ongoing battle against infection, examining the successes and failures of the past, along with how we are confronting the challenges of today, and our chances of eradicating disease in the future.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    And now it has been given the history it deserves’ Sunday TimesFor thousands of years the human heart remained the deepest of mysteries; both home to the soul and an organ too complex to touch, let alone operate on.Then, in the late nineteenth century, medics began going where no one had dared go before. The following decades saw the mysteries of the heart exposed, thanks to pioneering surgeons, brave patients and even sacrificial dogs.In eleven landmark operations, Thomas Morris tells us stories of triumph, reckless bravery, swaggering arrogance, jealousy and rivalry, and incredible ingenuity: the trail-blazing ‘blue baby’ procedure that transformed wheezing infants into pink, healthy children; the first human heart transplant, which made headline news around the globe. And yet the heart still feels sacred: just before the operation to fit one of the first artificial hearts, the patient’s wife asked the surgeon if he would still be able to love her.The Matter of the Heart gives us a view over the surgeon’s shoulder, showing us the heart’s inner workings and failings. It describes both a human story and a history of risk-taking that has ultimately saved millions of lives.

    People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number are experiencing something different: intact minds adrift deep within damaged brains and bodies. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life?