The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

    The effects of homeopathy don’t go away under rigorous scientific conditions. The laws of nature aren’t what they used to be. Thirty years on, no one has an explanation for a seemingly intelligent signal received from outer space. The US Department of Energy is re-examining cold fusion because the experimental evidence seems too solid to ignore. The placebo effect is put to work in medicine while doctors can’t agree whether it even exists.In an age when science is supposed to be king, scientists are beset by experimental results they simply can’t explain. But, if the past is anything to go by, these anomalies contain the seeds of future revolutions. While taking readers on an entertaining tour d’horizon of the strangest of scientific findings – involving everything from our lack of free will to Martian methane that offers new evidence of life on the planet – Michael Brooks argues that the things we don’t understand are the key to what we are about to discover.This mind-boggling but entirely accessible survey of the outer limits of human knowledge is based on a short article by Michael Brooks for New Scientist magazine. It became the sixth most circulated story on the internet in 2005, and provoked widespread comment and compliments (Google “13 things that do not make sense” to see).Michael Brooks has now dug deeply into those mysteries, with extraordinary results.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?

    We are now all too aware of how it is applied, but we know far less about how the idea came to be--and where it may yet go.Until Proven Safe tracks the idea of quarantine around the globe, through time and space, chasing the story from the lazarettos and quarantine islands of Venice--built before communicable diseases were really understood--to the hallways of the CDC, NASA, and the cutting-edge labs and conference rooms where the future technology of quarantine is being developed. The result is a tour of an idea that could not be more urgent or relevant, a book full of stories, people, and insights that is as compelling as it is definitive.

    The adjective 'medieval' has become a synonym for brutality and uncivilized behavior. Yet without the work of medieval scholars there could have been no Galileo, no Newton and no Scientific Revolution. In God's Philosophers, James Hannam debunks many of the myths about the Middle Ages, showing that medieval people did not think the earth is flat, nor did Columbus 'prove' that it is a sphere; the Inquisition burnt nobody for their science nor was Copernicus afraid of persecution; no Pope tried to ban human dissection or the number zero. God's Philosophers is a celebration of the forgotten scientific achievements of the Middle Ages - advances which were often made thanks to, rather than in spite of, the influence of Christianity and Islam. Decisive progress was also made in technology: spectacles and the mechanical clock, for instance, were both invented in thirteenth-century Europe. Charting an epic journey through six centuries of history, God's Philosophers brings back to light the discoveries of neglected geniuses like John Buridan, Nicole Oresme and Thomas Bradwardine, as well as putting into context the contributions of more familiar figures like Roger Bacon, William of Ockham and Saint Thomas Aquinas.

    Written by the man who started the adventure, Behind Deep Blue reveals the inside story of what happened behind the scenes at the two historic Deep Blue vs. Kasparov matches. This is also the story behind the quest to create the mother of all chess machines. The book unveils how a modest student project eventually produced a multimillion dollar supercomputer, from the development of the scientific ideas through technical setbacks, rivalry in the race to develop the ultimate chess machine, and wild controversies to the final triumph over the world's greatest human player.In nontechnical, conversational prose, Feng-hsiung Hsu, the system architect of Deep Blue, tells us how he and a small team of fellow researchers forged ahead at IBM with a project they'd begun as students at Carnegie Mellon in the mid-1980s: the search for one of the oldest holy grails in artificial intelligence--a machine that could beat any human chess player in a bona fide match. Back in 1949 science had conceived the foundations of modern chess computers but not until almost fifty years later--until Deep Blue--would the quest be realized.Hsu refutes Kasparov's controversial claim that only human intervention could have allowed Deep Blue to make its decisive, "uncomputerlike" moves. In riveting detail he describes the heightening tension in this war of brains and nerves, the "smoldering fire" in Kasparov's eyes. Behind Deep Blue is not just another tale of man versus machine. This fascinating book tells us how man as genius was given an ultimate, unforgettable run for his mind, no, not by the genius of a computer, but of man as toolmaker.

    Through the worst years of the Great Depression as many as five thousand laborers toiled twenty-four hours a day, seven days a week, to erect the huge structure that would harness the Colorado River and transform the American West.Construction of the giant dam was a triumph of human ingenuity, yet the full story of this monumental endeavor has never been told. Now, in an engrossing, fast-paced narrative, Joseph E. Stevens recounts the gripping saga of Hoover Dam. Drawing on a wealth of material, including manuscript collections, government documents, contemporary newspaper and magazine accounts, and personal interviews and correspondence with men and women who were involved with the construction, he brings the Hoover Dam adventure to life.Described here in dramatic detail are the deadly hazards the work crews faced as they hacked and blasted the dam’s foundation out of solid rock; the bitter political battles and violent labor unrest that threatened to shut the job down; the deprivation and grinding hardship endured by the workers’ families; the dam builders’ gambling, drinking, and whoring sprees in nearby Las Vegas; and the stirring triumphs and searing moments of terror as the massive concrete wedge rose inexorably from the canyon floor.Here, too, is an unforgettable cast of characters: Henry Kaiser, Warren Bechtel, and Harry Morrison, the ambitious, headstrong construction executives who gambled fortune and fame on the Hoover Dam contract; Frank Crowe, the brilliant, obsessed field engineer who relentlessly drove the work force to finish the dam two and a half years ahead of schedule; Sims Ely, the irascible, teetotaling eccentric who ruled Boulder City, the straightlaced company town created for the dam workers by the federal government; and many more men and women whose courage and sacrifice, greed and frailty, made the dam’s construction a great human, as well as technological, adventure.Hoover Dam is a compelling, irresistible account of an extraordinary American epic.

    A caring and thoughtful doctor, he also writes beautifully.” —Siddhartha Mukherjee, New York Times bestselling author on Modern Death In Heart of the Matter, Dr. Haider Warraich takes readers inside the ER, inside patients' rooms, and inside the history and technology of heart disease.More people die of heart disease than any other disease in the world, including even cancer. In fact, deaths from heart disease are on the rise around the world and in the United States. When any heart disease becomes advanced enough, it results in the development of heart failure. In the United States, heart failure is the most common reason for admission to the hospital. Heart failure strikes both the abject and the affluent. And yet, even the most basic facts about heart failure remain known by few who don’t work in medicine for a living. Many patients develop heart failure without having any problems with their coronary arteries. Heart failure can affect anyone at any time: a child recovering from a viral infection, a woman who has just given birth, a cancer patient who received chemotherapy or anyone with any number of common conditions such as high blood pressure, diabetes, or sleep apnea.Warraich's signature blend of lucid writing and compelling narrative explores the complex discussion about heart failure with accessibility and compassion.

    Among them would be history makers, including the first American woman and the first African American in space. This assembly of astronauts would carry NASA through the most tumultuous years of the space shuttle program. Four would die on Challenger. USAF Colonel Mike Mullane was a member of this astronaut class, and Riding Rockets is his story -- told with a candor never before seen in an astronaut's memoir. Mullane strips the heroic veneer from the astronaut corps and paints them as they are -- human. His tales of arrested development among military flyboys working with feminist pioneers and post-doc scientists are sometimes bawdy, often hilarious, and always entertaining. Mullane vividly portrays every aspect of the astronaut experience -- from telling a female technician which urine-collection condom size is a fit; to walking along a Florida beach in a last, tearful goodbye with a spouse; to a wild, intoxicating, terrifying ride into space; to hearing "Taps" played over a friend's grave. Mullane is brutally honest in his criticism of a NASA leadership whose bungling would precipitate the Challenger disaster. Riding Rockets is a story of life in all its fateful uncertainty, of the impact of a family tragedy on a nine-year-old boy, of the revelatory effect of a machine called Sputnik, and of the life-steering powers of lust, love, and marriage. It is a story of the human experience that will resonate long after the call of "Wheel stop."

    Would you know one if you held it in your hand?In Dark Archives, Megan Rosenbloom seeks out the historic and scientific truths behind anthropodermic bibliopegy--the practice of binding books in this most intimate covering. Dozens of such books live on in the world's most famous libraries and museums. Dark Archives exhumes their origins and brings to life the doctors, murderers, innocents, and indigents whose lives are sewn together in this disquieting collection. Along the way, Rosenbloom tells the story of how her team of scientists, curators, and librarians test rumored anthropodermic books, untangling the myths around their creation and reckoning with the ethics of their custodianship.A librarian and journalist, Rosenbloom is a member of The Order of the Good Death and a cofounder of their Death Salon, a community that encourages conversations, scholarship, and art about mortality and mourning. In Dark Archives--captivating and macabre in all the right ways--she has crafted a narrative that is equal parts detective work, academic intrigue, history, and medical curiosity: a book as rare and thrilling as its subject.

    The author assures us it is not!Three years before they came together, four young American men left their fraternities and college campuses for an adventure exceeding their imaginations. Wanting something more than the draft and unknown to each other, they chose Naval Aviation as the next step in their lives. Generally, they were better than their navy peers, all qualifying for high performance aircraft to be flown from steel decks over foreign seas. They would become the pointy end of the stick in aerial battles over North Vietnam, the most heavily defended patch of real estate in the history of aerial warfare. They were to do this in 1967, the year in which Naval Aviation experienced its greatest losses.These four young men, now Lieutenants Junior Grade, United States Navy, were ordered to Attack Squadron 34 to fly A4 Skyhawks into combat. They were assigned Junior Officer's stateroom 0111 aboard USS Intrepid, a venerable aircraft carrier with a distinguished history. This "bunkroom" better known to them as Triple Sticks was the repository for a log (in navy terms) or journal written by these four young aviators. Forty years later this log was the genesis of this memoir.In the lethal environment over the northern reaches of North Vietnam or ashore in the Officer's clubs and bars of Asia, the writing brings to life wonderful humor, bizarre behavior, vivid aerial battles, uncommon loyalty, anger, frustration and respect. One survived or did not according to his skill and luck.

    Hailed for her lifesaving efforts by President Ulysses S. Grant, Admiral Dewey, Susan B. Anthony, and other luminaries of the day, Lewis was the first person awarded a Congressional medal for her years of bravery and extraordinary heroism. Weaving thrilling nautical adventures with tales of other female lighthouse keepers, this compelling biography opens a fascinating and previously unexplored chapter in the history of American women.

    We are still waiting to find out who won. The Indy 500 was created to showcase the controversial new sport of automobile racing, which was sweeping the country. Daring young men were driving automobiles at the astonishing speed of 75 miles per hour, testing themselves and their vehicles. It was indeed a young man’s game: with no seat belts, hard helmets or roll bars, the dangers were enormous. When the Indianapolis Motor Speedway opened in 1909, seven people were killed, some of them spectators. Oil-slicked surfaces, clouds of smoke, exploding tires, and flying grit all made driving extremely hazardous, especially with the open-cockpit, windshield-less vehicles. Most drivers rode with a mechanic, who pumped oil manually while watching for cars attempting to pass. Drivers sometimes threw wrenches or bolts at each other during the race in order to gain an advantage. The night before an event, the racers would take up a collection for the next day’s new widows. Bookmakers offered bets not only on who might win but who might survive. Not all the participants in that first Indy 500 lived to see the checkered flag. Although the 1911 Indy 500 judges declared Ray Harroun, driving a Marmon Wasp, the official winner, there is reason to doubt that result. The timekeeping equipment failed, and the judges had to run for their lives when a driver lost control and his car spun wildly toward their stand. It took officials two days to determine the results, and Speedway authorities ordered the records to be destroyed. But Blood and Smoke is about more than a race, even a race as fabled as the Indianapolis 500. It is the story of America at the dawn of the automobile age, 29.99 a country in love with speed, danger, and spectacle. It is a story, too, about the young men who would risk their lives for money and glory, the sportsmen whose antics would thrill and outrage Americans in those long-ago days when the automobile was still brand new.

    and a PhD.  While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world’s first transplantation of the human liver in 1963.Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy.  His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation.  In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients.There are many heroes in the story of transplantation, and many “puzzle people,” the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts.  They are old and young, obscure and world famous.  Some have been taken into the hearts of America, like Stormie Jones, the brave and beautiful child from Texas.  Every patient who receives someone else’s organ - and Starzl remembers each one - is a puzzle.  “It was not just the acquisition of a new part,” he writes.  “The rest of the body had to change in many ways before the gift could be accepted.  It was necessary for the mind to see the world in a different way.”  The surgeons and physicians who pioneered transplantation were also changed: they too became puzzle people.  “Some were corroded or destroyed by the experience, some were sublimated, and none remained the same.”