. . If what we want in this moment is insight from this brilliant doctor about pandemics, he wants us to see that they do not occur in isolation. --Carolyn Kellogg, The Boston GlobeIn 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand--Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa's chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not - and the region's health care woes worsened, with devastating consequences that Farmer traces up to the present.This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.

    Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as to incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled book, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature, from Nero to Thomas Wainewright, and from the death of Socrates to Hamlet and Peter Pan. He discusses the sources of various poisons-from cyanide to strychnine, from Botox to ricin and Sarin gas-as well as their detection. Then he analyzes the science of their action in the body and their uses in medicine, cosmetics, war, and terrorism. With wit and precision, he weighs such questions as: Was Lincoln's volatility caused by mercury poisoning? Was Jack the Ripper an arsenic eater? Can wallpaper kill? For anyone who has ever wondered and been afraid to ask, here is a rich miscellany for your secret questions about toxins.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    Linda Burfield Hazzard. It was supposed to be a holiday for the two sisters. But within a month of arriving at what the locals called Starvation Heights, the women were emaciated shadows of their former selves, waiting for death. They were not the first victims of Linda Hazzard, a quack doctor of extraordinary evil and greed who would stop at nothing short of murder to achieve her ambitions. As their jewelry disappeared and forged bank drafts began transferring their wealth to Hazzard’s accounts, Dora Williamson sent a last desperate plea to a friend in Australia, begging her to save them from the brutal treatments and lonely isolation of Starvation Heights.In this true story—a haunting saga of medical murder set in an era of steamships and gaslights—Gregg Olsen reveals one of the most unusual and disturbing criminal cases in American history.

    The latest headlines feature the human papillomavirus (HPV) alleged to cause cervical cancer and the avian flu virus, H5N1. The public is also continually terrorized by reports about SARS, BSE, hepatitis C, AIDS, Ebola, and polio. However, this virus mayhem ignores very basic scientific facts: the existence, the pathogenicity and the deadly effects of these agents have never been proven. The authors of Virus Mania, journalist Torsten Engelbrecht and doctor of internal medicine Claus K�hnlein, show that these alleged contagious agents are, in fact, particles produced by the cells themselves as a consequence of certain stress factors such as drugs, malnutrition, pesticides and heavy metals.The central aim of this book is to steer the discussion back to a real scientific debate and put medicine back on the path of an impartial analysis of the facts. It will put medical experiments, clinical trials, statistics and government policies under the microscope, revealing that the people charged with protecting our health and safety have deviated from this path. To substantiate these statements, the authors cite dozens of highly renowned scientists and present approximately 1,100 pertinent scientific references.The topic of this book is of pivotal significance. The pharmaceutical companies and top scientists rake in enormous sums of money by attacking germs and the media boosts its audience ratings and circulations with sensationalized reporting (the coverage of the New York Times and Der Spiegel are specifically analyzed). "The primary purpose of commercially-funded clinical research is to maximize financial return on investment, not health," says John Abramson of Harvard Medical School. Virus Mania will inform you on how such an environment took root-and how to empower yourself for a healthy life.

    Yet, David Wootton argues, from the fifth century BC until the 1930s, doctors actually did more harm than good. In this controversial new account of the history of medicine, he asks just how much good it has done us over the years, and how much harm it continues to do today.

    These dramatic first-person essays detail spectacular serendipities, impossible cures, breathtaking resuscitations, extraordinary awakenings, and recovery from unimaginable disasters. Still other essays give voice to cases in which the physical aspects were less dramatic than the emotional aspects, yet miraculous and transformational for everyone involved. Positive impacts left in the wake of even the gravest of tragedies, profound triumphs of heart and spirit. Preeminent physicians in many specialties, including deans and department heads on the faculties of the top university medical schools in the country describe, in everyday language and with moving testimony, their very personal reactions to these remarkable clinical experiences. Among the extraordinary cases poignantly recounted by the physicians witnessing them: A priest visiting a hospitalized patient went into cardiac arrest on the elevator, which opened up on the cardiac floor, right at the foot of the cardiac specialist, at just the right moment.A tiny premature baby dying from irreversible lung disease despite the most intensive care who recovered almost immediately after being taken from his hospital bed and placed on his mother's chest.President John F. Kennedy's son Patrick, who died shortly after birth, and whose disease eventually led to research that saved generations of babies.A nine-year-old boy who was decapitated in a horrific car accident but survived without neurological damage.A woman who conceived and delivered a healthy baby—despite having had both of her fallopian tubes surgically removed.A young man whose only hope for survival was a heart transplant, but just at the moment he developed a potentially fatal complication making a transplant impossible, his own heart began healing itself.A teenage girl near death after contracting full-blown rabies who became the first patient ever to recover from that disease after an unexpected visit by Timothy Dolan, the man who would go on to become the Archbishop of New York.A Manhattan window-washer who fell 47 stories—and not only became the only person ever to survive a fall from that height, but went on to make a full recovery. Miracles We Have Seen is a book of inspiration and optimism, and a compelling glimpse into the lives of physicians—their humanity and determined devotion to their patients and their patients' families. It reminds us that what we don't know or don't understand isn‘t necessarily cause for fear, and can even be reason for hope

    Throughout history, more people have died in disease epidemics than in wars or other disasters. The courageous, trail-blazing defenders against these diseases faced a terrifying personal gamble. Often they were ignored, laughed at, or even fired from their jobs. But they kept hunting for answers, putting the pieces of the epidemic puzzle together. As they looked for clues to the origin of a disease, scientists searched for the unknown “patient zero”—the first person to have contracted it. Patient Zero brilliantly brings to life the main characters and events to tell the gripping tale of how each of seven diseases spread. The result is spine-chilling as Peters follows the scientists who solved the intricate mystery of the killer epidemics. Patient Zero reminds us that millions of people owe their lives to the work of these pioneer epidemiologists, work that continues to this day.

    Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns.The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

    In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

     Many people remember the beaming face of Christiaan Barnard, the South African surgeon, after he performed the first human heart transplant, and captured the world's imagination. It was a stunning achievement, but he was not alone. In truth it was a four-way race, a fierce struggle fraught with passionate rivalry. The other three surgeons-Adrian Kantrowitz, Norman Shumway, and Richard Lower-were giants in the field, and by early December 1967 they and Barnard were each poised to snatch the victor's laurels. Each had spent years perfecting techniques that would lead to a successful heart transplant; each had monitored his chosen patient's condition, watching the clock, hoping a donor would be found in time. Some of these men were friends; others were enemies. Only one of them would be the first. From a dank, underequipped hospital in Cape Town to a cramped lab in San Francisco, the surgeons worked their own individual miracles to prolong their patients' lives, testing the limits of science, and nature itself. Like the classics of medical adventure-from James Watson's The Double Helix to John Barry's The Great Influenza-Every Second Counts is an unforgettable story of not only competition and fame, but of life and death.

     Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, we still don't know exactly how or why these drugs work--or don't work--on what ails our brains. Blue Dreams offers the explosive story of the discovery, invention, people, and science behind our licensed narcotics, as told by a riveting writer and psychologist who shares her own intimate experience with the highs and lows of psychiatry's drugs. Lauren Slater's account ranges from the earliest, Thorazine and lithium, up through Prozac and other antidepressants, as well as Ecstasy, "magic mushrooms," the most cutting-edge memory drugs, and even neural implants. Along the way, she narrates the history of psychiatry itself, illuminating the imprint its colorful little capsules have left on millions of brains worldwide, and demonstrating how these wonder drugs may heal us or hurt us.

    Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys’ club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried. From her doctoral thesis, which changed the treatment of HIV-AIDS, saving the lives of millions, including basketball great Magic Johnson, to her spectacular discovery of a new family of human retroviruses, and her latest research which points to a new golden age of health, Dr. Mikovits has always been on the leading edge of science. With the brilliant wit one might expect if Erin Brockovich had a doctorate in molecular biology, Dr. Mikovits has seen the best and worst of science. When she was part of the research community that turned HIV-AIDS from a fatal disease into a manageable one, she saw science at its best. But when her investigations questioned whether the use of animal tissue in medical research were unleashing devastating plagues of chronic diseases, such as autism and chronic fatigue syndrome, she saw science at its worst. If her suspicions are correct, we are looking at a complete realignment of scientific practices, including how we study and treat human disease. Recounting her nearly four decades in science, including her collaboration of more than thirty-five years with Dr. Frank Ruscetti, one of the founders of the field of human retrovirology, this is a behind the scenes look at the issues and egos which will determine the future health of humanity.

    The Barbary Plague transports us to the Gold Rush boomtown in 1900, at the end of the city’s Gilded Age. With a deep understanding of the effects on public health of politics, race, and geography, Chase shows how one city triumphed over perhaps the most frightening and deadly of all scourges.