One can trace its roots to the Calculus of Variations and the work of Euler and Lagrange. This natural and reasonable approach to mathematical programming covers numerical methods for finite-dimensional optimization problems. It begins with very simple ideas progressing through more complicated concepts, concentrating on methods for both unconstrained and constrained optimization.

    From students with disabilities, culturally diverse students, and students with limited English proficiency to economically disadvantaged students this text provides teachers with the tools they need in their diverse classrooms. Revised to reflect the most current research, terminology and teaching practices, the strength of this text continues to be its numerous learning activities and sample lessons addressing both elementary and secondary classrooms. This edition continues its very popular multi- chapter unit on curriculum adaptations with specific strategies and activities for teaching reading, writing, and mathematics. With a new chapter on Response to Intervention and Progress Monitoring and full integration of the RTI framework, and the increase emphasis on middle and secondary students, this text continues its reign as an outstanding resource for all general education teachers. 0131381253 / 9780131381254 Teaching Students Who are Exceptional, Diverse, and at Risk in the General Education Classroom (with MyEducationLab) Package consists of 0135140870 / 9780135140871 MyEducationLab -- Access Card 0137151799 / 9780137151790 Teaching Students Who are Exceptional, Diverse, and at Risk in the General Education Classroom

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Building on the successful top-down approach of previous editions, this fourth edition continues with an early emphasis on application-layer paradigms and application programming interfaces, encouraging a hands-on experience with protocols and networking concepts.

    It illustrates both the cohesiveness of the relatively few fundamental ideas in this area and the great variety of problems these ideas solve. All of the problems address principles and procedures inherent in the design and anlysis of engineering structures and mechanical systems, with many of the problems referring explicitly to design considerations.

    This ninth edition covers both analytical and empirical approaches to the subject. The examples and templates provide students with resources for computer-numerical solutions.

    . . . Food transmutes directly into body, mind, and spirit . . . creates our day-to-day health and happiness.”—from The Macrobiotic Path to Total HealthEven in medical schools, alternative medicine is blossoming. Two thirds of them now offer courses in complementary healing practices, including nutrition. At the heart of this revolution is macrobiotics, a simple, elegant, and delicious way of eating whose health benefits are being confirmed at an impressive rate by researchers around the world.Macrobiotics is based on the laws of yin and yang—the complementary energies that flow throughout the universe and quicken every cell of our bodies and every morsel of the food we eat. Michio Kushi and Alex Jack, distinguished educators of the macrobiotic way, believe that almost every human ailment from the common cold to cancer can be helped, and often cured, by balancing the flow of energy (the ki) inside us. The most effective way to do this is to eat the right foods, according to our individual day-to-day needs. Now in this marvelous guide, they give us the basics of macrobiotic eating and living, and explain how to use this powerful source of healing to become healthier and happier, to prevent or relieve more than two hundred ailments, conditions, or disorders—both physical and psychological. This encyclopedic compendium of macrobiotic fundamentals, remedies, menus, and recipes takes into account the newest thinking and evolving practices within the macrobiotic community. The authors integrate all the information into a remarkable A to Z guide to macrobiotic healing—from AIDS, allergies, and arthritis, to cancer, diabetes, and heart disease. They also clearly explain what we need to know to start eating a true macrobiotic diet that will provide us with a complete balance of energy and nutrients. Living as we all do in environmental and climactic circumstances that are largely outside our personal control, it is vital that we follow a healthy lifestyle, including a flexible diet that we can adjust to meet our own individual needs. The Macrobiotic Path to Total Health gives us precisely the tools and the understanding we need to achieve this goal. Use it to build a strong, active body and a cheerful, resourceful mind.

    Its unique approach communicates the richness and diversity of CIS in a lucid and accessible format. This fully revised and updated second edition reinforces the view of CIS as a gateway to science and problem solving, sets out the scientific principles that govern its use, and describes the impact of people on its development, design, and success. The second edition of Geographic Information Systems and Science includes:A new five-part structure: Foundations; Principles; Techniques; Analysis; and Management and Policy.All-new personality boxes of current GIS practitioners.New real-world applications of GIS.New or expanded coverage of important current topics:Location-based servicesDistributed computingVirtual and augmented realitiesHomeland securityBusiness GIS and geodemographicsThe emergence of geoportalsGrand challenges of GIScienceA new suite of instructor and student resources http://www.wiley.com/go/longleyThe second edition of Geographic Information Systems and Science is essential reading for undergraduates taking courses in GIS within departments of Geography, Environmental Science, Business (and Public) Administration, Computer Science, Urban Studies, Planning, Information Science, Civil Engineering, and Archaeology. It is also provides a key resource for foundation GIS courses on taught MSc and other higher-degree programs. Professional users of GIS from governmental organizations and industries across the private sector will find this book an invaluable resource with a wealth of relevant applications.

    Most undergraduates have to undertake some form of literature review which may be daunting, this book explains it in an clear, easy to understand format. Explanations are given as to why undertaking a literature review is undertaken. Summery sections at the end of each chapter allow the reader to reflect on what they have just read, allowing the information to sink in. This book should be on every university's recommended reading list." Kerry Davis, Student Nurse, University Campus Suffolk, UK" ""This book is fantastic! It gives a clear, concise guide to carrying out a literature review, which is of course a widely used formative assessment technique in a nursing program ... (it includes) in depth explanations and reasons as to how and why it is important to do a literature review ... the summary section at the end of each chapter is excellent, and allows the reader to review their understanding of what they're just read. Overall an excellent book which is a must for any student nurse!" Gem Smith, Student Nurse, Northumbria University, UK"""This book is superb. It explains the entire process of writing a literature review very clearly ... extremely helpful as the prospect of reviewing literature can be quite daunting." Vicky Bain, Student Nurse, University of Nottingham, UK"A comprehensive, easy to read guide which will help students to understand how to undertake a literature review, and how to use the resultant information effectively." Anne-Marie Warnes, University of Central Lancashire, UK"As a student, currently writing a literature review, I found this an extremely helpful book, which is invaluable in demystifying some of the more challenging elements, while at the same time providing clear, simple, appealing and appropriate guidance. This is a must have for undergraduate nursing students, and indeed all healthcare students embarking on such projects." Audrey Grace, Trinity College Dublin, Dublin, Ireland"This bestselling book is a step-by-step guide to doing a literature review in health and social care. It is vital reading for all those undertaking their undergraduate or postgraduate dissertation or any research module which involves a literature review.The new edition has been fully updated and provides a practical guide to the different types of literature that you may come across when undertaking a literature review. It includes: Examples of commonly occurring real life scenarios encountered by students Emphasis on the importance of setting a question at the very start of the project Advice on how to follow a clearly defined search strategy Details of a wide range of critical appraisal tools "Doing a Literature Review in Health and Social Care 2/e" is essential reading for students at all levels within the health and social care field - and a useful text for anyone new to reviewing and appraising evidence.

    This new edition simplifies many of the steps involved in analysis by using the computer application Excel. Over 100 detailed example problems illustrate important fluid mechanics concepts: Approximately 1300 end-of-chapter problems are arranged by difficulty level and include many problems that are designed to be solved using Excel. The CD for the book includes: A Brief Review of Microsoft Excel and numerous Excel files for the example problems and for use in solving problems. The new edition includes an expanded discussion of pipe networks, and a new section on oblique shocks and expansion waves.

    The beginning chapters introduce basic chemical and biological concepts to provide students with the framework they need to comprehend physiological principles. The chapters that follow promote conceptual understanding rather than rote memorization of facts. Health applications are included throughout the book to heighten interest, deepen understanding of physiological concepts, and help students relate the material to their individual career goals. Every effort has been made to help students integrate related concepts and understand the relationships between anatomical structures and their functions.

    Emphasis is placed upon the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. The text also introduces students to elementary integrated circuitry, microprocessors and computers, and treatment of analytical data.

    

    But that does not even begin to convey what the Berger experience is: What makes these bestselling textbooks so distinctive is the unmistakable presence of KATHLEEN STASSEN BERGER on every page, in writing that continually draws on the author’s teaching and family life to demonstrate a remarkable understanding not just of the field, but of students’ questions, their concerns, and their lives.The distinctive, definitive BERGER touch is evident throughout her new textbook, Invitation to the Life Span. This brief, original, 15-chapter textbook was created from page 1 to address the challenges teachers and students face when covering the entire life span in a semester (or even a quarter!). The hallmark Berger qualities are all here—the relatable presentation of research, the inclusive approach to world cultures, the study help that builds critical thinking and observational skills, the outstanding media and supplements—and all held together with Berger’s skill in bringing students and the science together.

    Yet they endlessy fascinate and continue to capture the public's attention with their strange charisma and deadly deeds. From Jack the Ripper to Ted Bundy and the Moors Murderers Ian Brady and Myra Hindley, these killers transfix us with their ability to commit utterly savage acts of cruelty and depravity. Only with modern police detection methods and psychological profiling, have these figures that have existed throughout human history finally been identified in the deadliest category: serial killers. These methods, the killers' characters and their crimes are described here in fascinating and terrifyingly gripping detail. The whole history of serial killers is brought to life in 50 chapters, including: Herman Webster Mudget, Devil in the White City John Christie, 10 Rillington Place murders Zodiac Killer Ian Brady and Myra Hindley, The Moors Murderers Ted Bundy Fred and Rosemary West Jeffrey Dahmer Aileen Wuornos Harold Shipman, Dr Death