is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    Citing her original NASA research on how weightlessness weakens astronauts' muscles, bones, and overall health, the author presents a simple and effective plan for maintaining good health throughout life by developing new lifestyle habits of frequent gravity-challenging movement. Written for everyone who spends most of their lives sitting in chairs, at desks, and in cars, this practical, easy-to-follow action plan outlines simple gravity-challenging activities such as standing up frequently, stretching, walking, and dancing that are more healthful and effective than conventional diet and exercise regimens.

    In this engrossing title, a nurse practitioner uses her unique combination of skills to write about the world of women's health in a new way.

    For the first time ever, these 48 invaluable answers have all been compiled into one handy reference – no stone is left unturned. Amongst other things, you’ll finally know how to: Market, sell, and keep clients (pg 33) Get your career started right (pg 13) Deal with all possible objections (pg 65) Deal with difficult client types (pg 79) Become more organized and efficient every day (pg 91) Turn your job into a career by making more money both in-training, and beyond (pg 139). With the Personal Trainer Pocketbook by your side, you’ll never be alone again.

    In his first two books, Dr. Dale Bredesen outlined the revolutionary treatments that are changing what had previously seemed like the inevitable outcome of cognitive decline and dementia. And in these moving narratives, you can hear directly from the first survivors of Alzheimer's themselves--their own amazing stories of hope told in their own words. These first person accounts honestly detail the fear, struggle, and ultimate victory of each patient's journey. They vividly describe what it is like to have Alzheimer's. They also drill down on how each of these patients made the program work for them--the challenges, the workarounds, the encouraging results that are so motivating. Dr. Bredesen includes commentary following each story to help point readers to the tips and tricks that might help them as well.Dr. Bredesen's patients have not just survived; they have thrived to rediscover fulfilling lives, rewarding relationships, and meaningful work. This book will give unprecedented hope to patients and their families.

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.

    But in the scalp of a balding man, they do not get everything they need and as a result, the hair-producing cells gradually die off. Here we have an example of a mild ‘disease’ which is caused by cellular malnutrition.” —Dr. Roger J. Williams “A living cell requires energy not only for all of its functions, but also for maintenance of its structure.” —Nobel Laureate Albert Szent-Györgyi "What could be more important to understand than biological energy? Thought, growth, movement, every philosophical and practical issue involves the nature of biological energy.” —Raymond Peat, PhD ======== The Current View of Pattern Hair Loss is Unproductive (and Dangerous) While it is often stated with great confidence that pattern pattern hair loss is the result of defective genes and "male" androgenic hormones (e.g., dihydrotestosterone or DHT), the theory is physiologically unsound. After 60 years of research the "genetic-androgen" hypoheses has produced a single FDA-approved "therapy" that works less than 50% the time and can result in permanent chemical castration (Minoxidil is a nonstarter for many men and women). In contrast, castrates and pseudohermaphrodites--who serve as the foundation for all baldness research--are protected from pattern hair loss 100% of the time. Steps Towards a 'Bioenergetic' View of Pattern Hair Loss Standing on the shoulders of giants (e.g., Otto Warburg, Albert Szent-Györgyi, Gilbert Ling, Ray Peat and others), HAIR LIKE A FOX sets up an alternative 'bioenergetic model' of pattern hair loss with a focus on the smallest unit of life, the cell. This same context elucidates simple yet effective therapies for halting and perhaps reversing pattern hair loss in a way that harmonizes with our unique physiology.

    Saag, MD, an internationally known expert on the virus that causes AIDS, but the book is more than a memoir: through his story, Dr. Saag also shines a light on the dysfunctional US healthcare system, proposing optimistic yet realistic remedies drawn from his distinguished medical career.Mike Saag began his medical residency in 1981, within days of the Centers for Disease Control’s first report of a mysterious “gay cancer” killing young men. Soon, the young doctor’s career was yoked to the epidemic. His life’s work became turning the most deadly virus in human history into a chronic, manageable disease.In the lab at the University of Alabama at Birmingham, Dr. Saag and colleagues made seminal early discoveries about the elusive virus. And at the AIDS clinic he founded, Dr. Saag met people whose fight against a virtual death sentence touched his heart and inspired him to work even harder. As his career stretched across three decades, Dr. Saag found himself battling another foe, this one almost as pernicious as AIDS itself: a broken healthcare system shaped more by politicians, insurers, and lobbyists than by patients’ needs.Positive is Dr. Saag’s tribute to the unforgettable patients he has known and an urgent call to create a comprehensive, compassionate, accessible healthcare system in the name of those we can save today.

    The truth is, this isn’t a government problem. It’s our own fault. In this thought-provoking book, board certified medical doctor Nicole Saphier calls on all Americans to take responsibility for their individual health. Americans are notoriously unhealthy—we eat too much, drink too much, and sit too much. When roughly 80% of cardiovascular disease and 40% of all cancer cases could be prevented by simple lifestyle changes, it is time to take a deeper look at the problem and ask who truly is responsible. Saphier contends that by getting healthier, we can reduce the astronomical cost of treatment and improve overall care. We don’t need socialized medicine—we need to take better care of ourselves.In Make America Healthy Again, Saphier combines historical events, economic trends, essential lifestyle advice, and her own perspective to offer concrete solutions to address this massive problem. As she examines a wide range of topics, including the leading causes of death, mental health stigma, social media, physician burnout, and the opioid crisis, Saphier offers a much-needed alternative perspective on the healthcare debate.The only way to lower health care costs for everyone is to stop incentivizing bad health decisions. Plans like “Medicare for all” would allow Americans to continue to eat poorly and lead sedentary lives. We can’t keep expecting doctors to fix behaviors that we have in our power to prevent, she argues. It’s only going to get worse unless we take action. It’s up to the American people to make America healthy again.

    And now Dr. Jesse Payne, Director of Education at the Amen Clinics, is bringing the groundbreaking science of the Change Your Brain program to a whole new generation of readers. The brain is particularly malleable until the age of 25, which means that even more than your parents or your teachers, you have the power to change your brain. And the things you do today—from what you eat, to how you sleep, to what you do for fun—can change your brain in drastic ways. This book provides a powerful, prescriptive program for you to avoid the common dangers and pitfalls that can jeopardize your future and train your brain for a lifetime of success. Discover how to *Improve academic performance *�Nurture creativity *�Treat diagnoses like ADD, ADHD and depression *�Enhance relationship skills *�Increase organization *�Improve memory *�Boost mood *�And more! Featuring stories from real teens and young adults along with actual brain scans that show how effectively this program works, Change Your Brain, Change Your Life (Before 25) is perfect for teens and young adults, their parents and the professionals who work with them. Turn the page for a bright future and a successful tomorrow.

    James Hirsch’s myth-shattering blend of history, reportage, advocacy, and memoir will speak for, and to, the 20 million Americans who live with this disease. Cheating Destiny offers revealing views of the diabetic subculture, the urge toward secrecy that many diabetics feel, the glycemic rollercoaster they ride constantly, and the remarkable perseverance—even heroism—required for survival.Hirsch is uniquely qualified to write this book. An award-winning journalist and best-selling author, he has lived with type 1 diabetes for twenty-five years. His brother Irl, also a diabetic, is one of the country’s leading diabetologists. Most poignantly, he knows firsthand the toll diabetes can take on parents: his three-year-old son was diagnosed with the disease while Hirsch was writing this book.Hirsch draws on all this expertise to craft an incisive, surprising portrayal of the fascinating science behind the disease and the skyrocketing impact of diabetes on our economy and society. Most striking is his candid, authoritative writing about the psychological and emotional hurdles that diabetics confront every day. Anyone who lives with diabetes—or loves a diabetic—will find here an empowering voice of empathy.

    With Step By Step, you set the pace-building and practicing the skills you need, just when you need them! Topics include building a project plan and fine-tuning the details; scheduling tasks, assigning resources, and managing dependencies; monitoring progress and costs; keeping projects on track; communicating project data through Gantt charts and other views.

    Otto’s subjects include the pioneering dentist who made Shirley Temple and Judy Garland’s teeth sparkle on the silver screen and helped create the all-American image of “pearly whites”; Deamonte Driver, the young Maryland boy whose tragic death from an abscessed tooth sparked congressional hearings; and a marketing guru who offers advice to dentists on how to push new and expensive treatments and how to keep Medicaid patients at bay.In one of its most disturbing findings, Teeth reveals that toothaches are not an occasional inconvenience, but rather a chronic reality for millions of people, including disproportionate numbers of the elderly and people of color. Many people, Otto reveals, resort to prayer to counteract the uniquely devastating effects of dental pain.Otto also goes back in time to understand the roots of our predicament in the history of dentistry, showing how it became separated from mainstream medicine, despite a century of growing evidence that oral health and general bodily health are closely related.Muckraking and paradigm-shifting, Teeth exposes for the first time the extent and meaning of our oral health crisis. It joins the small shelf of books that change the way we view society and ourselves—and will spark an urgent conversation about why our teeth matter.This is an alternate cover edition of ISBN 9781620971444.

    From a fortress-like former bank building, American Pain's doctors distributed massive quantities of oxycodone to hundreds of customers a day, mostly traffickers and addicts who came by the vanload. Inked muscle-heads ran the clinic's security. Former strippers operated the pharmacy, counting out pills and stashing cash in garbage bags. Under their lab coats, the doctors carried guns and it was all legal sort of. American Pain was the brainchild of Chris George, a 27-year-old convicted drug felon. The son of a South Florida home builder, Chris George grew up in ultra-rich Wellington, where Bill Gates, Springsteen, and Madonna kept houses. Thick-necked from weightlifting, he and his twin brother hung out with mobsters, invested in strip clubs, brawled with cops, and grinned for their mug shots. After the housing market stalled, a local doctor clued in the brothers to the burgeoning underground market for lightly regulated prescription painkillers. In Florida, pain clinics could dispense the meds, and no one tracked the patients. Seizing the opportunity, Chris George teamed up with the doctor, and word got out. Just two years later Chris had raked in $40 million, and 90 percent of the pills his doctors prescribed flowed north to feed the rest of the country's insatiable narcotics addiction. Meanwhile, hundreds more pain clinics in the mold of American Pain had popped up in the Sunshine State, creating a gigantic new drug industry. American Pain chronicles the rise and fall of this game-changing pill mill, and how it helped tip the nation into its current opioid crisis, the deadliest drug epidemic in American history. The narrative swings back and forth between Florida and Kentucky, and is populated by a gaudy and diverse cast of characters. This includes the incongruous band of wealthy bad boys, thugs and esteemed physicians who built American Pain, as well as penniless Kentucky clans who transformed themselves into painkiller trafficking rings. It includes addicts whose lives were devastated by American Pain's drugs, and the federal agents and grieving mothers who labored for years to bring the clinic's crew to justice."

     Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.