After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    She draws from her own experiences of illness and bodily injury to engage in an exploration that extends far beyond her life, spanning wide-ranging territory—from poverty tourism to phantom diseases, street violence to reality television, illness to incarceration—in its search for a kind of sight shaped by humility and grace.

    As he would later write in the first of a series of award-winning columns for "Vanity Fair," he suddenly found himself being deported "from the country of the well across the stark frontier that marks off the land of malady." Over the next eighteen months, until his death in Houston on December 15, 2011, he wrote constantly and brilliantly on politics and culture, astonishing readers with his capacity for superior work even in extremis.Throughout the course of his ordeal battling esophageal cancer, Hitchens adamantly and bravely refused the solace of religion, preferring to confront death with both eyes open. In this account of his affliction, he describes the torments of illness, discusses its taboos, and explores how disease transforms experience and changes our relationship to the world around us. By turns personal and philosophical, Hitchens embraces the full panoply of human emotions as cancer invades his body and compels him to grapple with the enigma of mortality.

    What began as the chronicle of an imminent and early death became something much more--a powerful exhortation to the living.That Julie Yip-Williams survived infancy was a miracle. Born blind in Vietnam, she narrowly escaped euthanasia at the hands of her grandmother, only to flee with her family the political upheaval of her country in the late 1970s. Loaded into a rickety boat with three hundred other refugees, Julie made it to Hong Kong and, ultimately, America, where a surgeon at UCLA gave her partial sight. She would go on to become a Harvard-educated lawyer, with a husband, a family, and a life she had once assumed would be impossible. Then, at age thirty-seven, with two little girls at home, Julie was diagnosed with terminal metastatic colon cancer, and a different journey began.The Unwinding of the Miracle is the story of a vigorous life refracted through the prism of imminent death. When she was first diagnosed, Julie Yip-Williams sought clarity and guidance through the experience and, finding none, began to write her way through it--a chronicle that grew beyond her imagining. Motherhood, marriage, the immigrant experience, ambition, love, wanderlust, tennis, fortune-tellers, grief, reincarnation, jealousy, comfort, pain, the marvel of the body in full rebellion--this book is as sprawling and majestic as the life it records. It is inspiring and instructive, delightful and shattering. It is a book of indelible moments, seared deep--an incomparable guide to living vividly by facing hard truths consciously.With humor, bracing honesty, and the cleansing power of well-deployed anger, Julie Yip-Williams set the stage for her lasting legacy and one final miracle: the story of her life.

    It includes tales of living on her own at 14 (and how laundry may have saved her life), getting stuck in a gas station overhang on a cross country road trip, saying goodbye to her father in a way only he could have understood, and many more adventures and lessons that have led her to the successful, happy, and healthy place she is today.

    The next morning, things take a sharp turn as she’s led from work to the emergency room. By the end of the week, a neurologist delivers a devastating prognosis: Sarah suffered a traumatic brain injury that has caused her IQ to plummet, with no hope of recovery. Her brain has irrevocably changed.Afraid of judgment and deemed no longer fit for work, Sarah isolates herself from the outside world. She spends months at home, with her dogs as her only source of companionship, battling a personality she no longer recognizes and her shock and rage over losing simple functions she’d taken for granted. Her life is consumed by fear and shame until a chance encounter gives Sarah hope that her brain can heal. That conversation lights a small flame of determination, and Sarah begins to push back, painstakingly reteaching herself to read and write, and eventually reentering the workforce and a new, if unpredictable, life.In this highly intimate account of devastation and renewal, Sarah pulls back the curtain on life with traumatic brain injury, an affliction where the wounds are invisible and the lasting effects are often misunderstood. Over years of frustrating setbacks and uncertain triumphs, Sarah comes to terms with her disability and finds love with a woman who helps her embrace a new, accepting sense of self.

     From the author of the sensational bestseller I Was Told There'd Be Cake comes a new book of personal essays brimming with all the charm and wit that have earned Sloane Crosley widespread acclaim, award nominations, and an ever-growing cadre of loyal fans. In Cake readers were introduced to the foibles of Crosley's life in New York City-always teetering between the glamour of Manhattan parties, the indignity of entry-level work, and the special joy of suburban nostalgia-and to a literary voice that mixed Dorothy Parker with David Sedaris and became something all its own.Crosley still lives and works in New York City, but she's no longer the newcomer for whom a trip beyond the Upper West Side is a big adventure. She can pack up her sensibility and take us with her to Paris, to Portugal (having picked it by spinning a globe and putting down her finger, and finally falling in with a group of Portuguese clowns), and even to Alaska, where the "bear bells" on her fellow bridesmaids' ponytails seemed silly until a grizzly cub dramatically intrudes. Meanwhile, back in New York, where new apartments beckon and taxi rides go awry, her sense of the city has become more layered, her relationships with friends and family more complicated.As always, Crosley's voice is fueled by the perfect witticism, buoyant optimism, flair for drama, and easy charm in the face of minor suffering or potential drudgery. But in How Did You Get This Number it has also become increasingly sophisticated, quicker and sharper to the point, more complex and lasting in the emotions it explores. And yet, Crosley remains the unfailingly hilarious young Every woman, healthily equipped with intelligence and poise to fend off any potential mundanity in maturity.Show me the doll --Lost in space --Take a stab at it --It's always home you'll miss --Light pollution --If you sprinkle --An abbreviated catalog of tongues --Le Paris! --Off the back of a truck

    She'll take you searching for bodies of loved ones - through woodlands, along hedgerows, field-edges, and through plantations - solving time since death, and disposal of remains, from ditches to living rooms. She will give you glimpses of her own history: her loves, her losses, and the narrow little valley in Wales where she first woke up to the wonders of the natural world. Pat will show you how her work with a microscope reveals tell-tale traces of the world around us, and how these have taken suspects of the darkest criminal activities to court.From flowers, fungi, tree trunks to car pedals, walking boots, carpets, and corpses' hair, Traces is a unique book on life, death, and one's indelible link with nature.

    Now she’s distilled what she’s learned about how to live a more exhilarating and meaningful life into three words: find the good. It’s that simple--and that hard. Quirky and profound, individual and universal, Find the Good offers up short chapters that help us unlearn the habit--and it is a habit--of seeing only the negatives. Lende reminds us that we can choose to see any event--starting a new job or being laid off from an old one, getting married or getting divorced--as an opportunity to find the good. As she says, “We are all writing our own obituary every day by how we live. The best news is that there’s still time for additions and revisions before it goes to press.” Ever since Algonquin published her first book, the New York Times bestseller If You Lived Here, I’d Know Your Name, Heather Lende has been praised for her storytelling talent and her plainspoken wisdom. The Los Angeles Times called her “part Annie Dillard, part Anne Lamott,” and that comparison has never been more apt as she gives us a fresh, positive perspective from which to view our relationships, our obligations, our priorities, our community, and our world. An antidote to the cynicism and self-centeredness that we are bombarded with every day in the news, in our politics, and even at times in ourselves, Find the Good helps us rediscover what’s right with the world. “Heather Lende’s small town is populated with big hearts--she finds them  on the beach, walking her granddaughters, in the stories of ordinary peoples’ lives, and knits them into unforgettable tales. Find the Good is a treasure.” —Jo-Ann Mapson, author of Owen’s Daughter “Find the Good is excellent company in unsteady times . . . Heather Lende is the kind of person you want to sit across the kitchen table from on a rainy afternoon with a bottomless cup of tea. When things go wrong, when things go right, her quiet, commonsense wisdom, self-examining frankness, and good-natured humor offer a chance to reset, renew, rebalance.”  —Pam Houston, author of Contents May Have Shifted “With gentle humor and empathy [Lende] introduces a number of people who provide examples of how to live well . . . [Find the Good] is simple yet profound.”  —Booklist “In this cynical world, Find the Good is a tonic, a literary wellspring, which will continue to run, and nurture, even in times of drought. What a brave and beautiful thing Heather Lende has made with this book.” —John Straley, Shamus Award winner and former writer laureate of Alaska “Heather Lende is a terrific writer and terrific company: intimate, authentic, and as quirky as any of her subjects.” —Marilyn Johnson, author of The Dead Beat

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    At fifteen, he took a job washing dishes in a local comedy club—just so he could watch endless stand-up for free. At sixteen, he was hosting a show for his local high school radio station in Syosset, Long Island—a show that consisted of Q&As with his comedy heroes, from Garry Shandling to Jerry Seinfeld. They talked about their careers, the science of a good joke, and their dreams of future glory (turns out, Shandling was interested in having his own TV show one day and Steve Allen had already invented everything).Thirty years later, Apatow is still that same comedy nerd—and he’s still interviewing funny people about why they do what they do.Sick in the Head gathers Apatow’s most memorable and revealing conversations into one hilarious, wide-ranging, and incredibly candid collection that spans not only his career but his entire adult life. Here are the comedy legends who inspired and shaped him, from Mel Brooks to Steve Martin. Here are the contemporaries he grew up with in Hollywood, from Spike Jonze to Sarah Silverman. And here, finally, are the brightest stars in comedy today, many of whom Apatow has been fortunate to work with, from Seth Rogen to Amy Schumer. And along the way, something kind of magical happens: What started as a lifetime’s worth of conversations about comedy becomes something else entirely. It becomes an exploration of creativity, ambition, neediness, generosity, spirituality, and the joy that comes from making people laugh.Loaded with the kind of back-of-the-club stories that comics tell one another when no one else is watching, this fascinating, personal (and borderline-obsessive) book is Judd Apatow’s gift to comedy nerds everywhere.Praise for Sick in the Head“I can’t stop reading it. . . . I don’t want this book to end.”—Jimmy Fallon “An essential for any comedy geek.”—Entertainment Weekly “Fascinating . . . a collection of interviews with many of the great figures of comedy in the latter half of the twentieth century.” —The Washington Post “Open this book anywhere, and you’re bound to find some interesting nugget from someone who has had you in stitches many, many times.”—Janet Maslin, The New York Times “An amazing read, full of insights and connections both creative and interpersonal.”—The New Yorker “Fascinating and revelatory.” —Chicago Tribune “For fans of stand-up, Sick in the Head is a Bible of sorts.”—Newsweek“These are wonderful, expansive interviews—at times brutal, at times breathtaking—with artists whose wit, intelligence, gaze, and insights are all sharp enough to draw blood.”—Michael Chabon “Anyone even remotely interested in comedy or humanity should own this book. It is hilarious and informative and it contains insightful interviews with the greatest comics, comedians, and comediennes of our time. My representatives assure me I will appear in a future edition.”—Will FerrellFrom the Hardcover edition.

    In this remarkable symphony of essays adapted and expanded from his ground-breaking, critically acclaimed podcast, John Green reviews different facets of the human-centered planet - from the QWERTY keyboard and Halley's Comet to Penguins of Madagascar - on a five-star scale.Complex and rich with detail, the Anthropocene's reviews have been praised as 'observations that double as exercises in memoiristic empathy', with over 10 million lifetime downloads. John Green's gift for storytelling shines throughout this artfully curated collection about the shared human experience; it includes beloved essays along with six all-new pieces exclusive to the book.

    Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn't know it then, but dementia was starting to take hold. In 2014, at age fifty-eight, she was diagnosed with young-onset Alzheimer's.Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off. What lay ahead of her after the diagnosis was scary and unknowable, but Mitchell was determined and resourceful, and she vowed to outwit the disease for as long as she could.As Mitchell learned to embrace her new life, she began to see her condition as a gift, a chance to experience the world with fresh eyes and to find her own way to make a difference. Even now, her sunny outlook persists: She devotes her time to educating doctors, caregivers, and other people living with dementia, helping to reduce the stigma surrounding this insidious disease.Still living independently, Mitchell now uses Post-it notes and technology to remind her of her routines and has created a "memory room" where she displays photos--with labels--of her daughters, friends, and special places. It is a room where she feels calm and happy, especially on days when the mist descends.

    The book opens with his father's fond, vivid portrait of his son - a young man of extraordinary intellectual promise, who excelled at physics, math, and chess, but was also an active, good-hearted, and fun-loving kid. But the heart of the book is a description of the agonized months during which Gunther and his former wife Frances try everything in their power to halt the spread of Johnny's cancer and to make him as happy and comfortable as possible. In the last months of his life, Johnny strove hard to complete his high school studies. The scene of his graduation ceremony from Deerfield Academy is one of the most powerful - and heartbreaking - in the entire book. Johnny maintained his courage, wit and quiet friendliness up to the end of his life. He died on June 30, 1947, less than a month after graduating from Deerfield.