In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.

    In this hilarious, high-spirited, sometimes harrowing memoir, Shapiro invites us into his battle with cancer, his romance with an oncology nurse, his journey through graduate school, and his most important life lessons. He tells his story with wit and grace and indomitable spirit, showing us that only when the rhythm of life is stirred violently are able to discover its full beauty.

    It promised to shed light on the deep mysteries of consciousness, as well as offer relief to addicts and the mentally ill. But in the 1960s, with the vicious backlash against the counter-culture, all further research was banned. In recent years, however, work has quietly begun again on the amazing potential of LSD, psilocybin and DMT. Could these drugs in fact improve the lives of many people? Diving deep into this extraordinary world and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of human consciousness.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    Through her teachings and his own mind-bending experiences, he gives us a glimpse into an alternate reality.

    A who's who of pathology experts delivers the most dependable, current, and complete coverage of today's essential pathology knowledge. At the same time, masterful editing and a practical organization make mastering every concept remarkably easy. Online access via Student Consult includes self-assessment and review questions, interactive case studies, downloadable images, videos, and a virtual microscope that lets you view slides at different magnifications. The result remains the ideal source for an optimal understanding of pathology. Offers the most authoritative and comprehensive, yet readable coverage available in any pathology textbook, making it ideal for USMLE or specialty board preparation as well as for course work. Includes access to the complete contents online via Student Consult, along with self-assessment and review questions, over 100 interactive clinical case studies, videos, and a virtual microscope that lets users view slides at different magnifications.Delivers a state-of-the-art understanding of the pathologic basis of disease through completely updated coverage, including the latest cellular and molecular biology.Demonstrates every concept visually with over 1,600 full-color photomicrographs and conceptual diagrams - many revised for even better quality.Facilitates learning with an outstanding full-color, highly user-friendly design.

    We both looked after Sophie and her baby. We had to. It’s not like Sophie was going to look after that baby herself. All she was interested in was weeping and wailing for her dead husband. She was so busy weeping and wailing for her dead husband that she rejected his baby who was right in front of her.When Olga’s friend Lara becomes a grandmother, Olga helps out whenever she can. After all, it’s a big imposition on Lara, looking after her bereaved daughter and the baby. And the new mother is not exactly considerate.But smoldering beneath Olga’s sensible support and loving generosity is a deep jealous need to be the centre of Lara’s attention and affection—a need that soon becomes a consuming, dangerous and ultimately tragic obsession.Gigi Fenster’s A Good Winter is an enthralling psychological thriller, a dark and complex portrait of a troubled mind.

    

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    a towering tale of dreams unfettered, of mustangs running free, and of young men riding hell-bent-for-leather into Indian country for no other reason than they were young, brave and wild.By 1900 the Old West was vanishing, but the man many called its fastest gun was still alive.  By then Car Brules had shut himself and his secrets away in a cabin on Colorado's Lone Cone Peak.  Only one person knew his real story, a boy of eleven who became his friend and heard his extraordinary tales in 1909.  The Scout is that unforgettable story, just as young Steven Cartwright heard it, just as Brules told it: hard and gritty, wry with a cowboy's humor, and true to the spirits of all those who loved the west--and died for it--from Custer to Crazy Horse.Many hard, hurting things had driven Cat Brules to become the man he was.  The death of his beloved Shoshone bride, Wild Rose, was one of them.  Months after Brules lost her--brutally and far too soon--Wild Rose still came to him in his dreams.  With a void in his heart and a reckless spirit, Brules signed on as a Scout for General George Crook, whose cavalry was headed into the Badlands. Then, the U.S. Army still didn't know that there were fifteen thousand Sioux and Cheyenne in those Wyoming foothills, and under chiefs Sitting Bull and Crazy Horse, every one of them was willing to fight to the death to live free.Brules's account of the violence that ensued, told with eyewitness immediacy and chilling authenticity, is one of courage and shame as he rides the trail toward the Little Big Horn and the battles that followed.  Seeing for himself the dying of a way of life, Brules tells a searing truth about America's history: the betrayal of Custer to the Sioux, the hunting of Geronimo, and the U.S. Army's cruel pursuit of Chief Joseph and his Nez Perce.  And here too are the women who loved Brules: White Antelope, the gentle Indian maiden who wanted what Brules felt he could never give again--and Melisande, the saucy Mormon girl who might be too much for even Cat Brules to handle.Debunking the myths of the Old West and the romanticism of movies, renowned Western writer Harry Combs creates a vision at once more complex, magnificent and genuine--from the make of the rifle to the caliber of the bullet that cut Custer down.  A novel unmatched in excitement and adventure, The Scout lets you smell the cordite, feel a man's hard need for a woman, and discover that the real flesh and blood inhabitants of those legendary days were tougher, bolder and more fascinating than we ever dared to imagine.

    It is the people living in it that are ugly."For centuries it has been tradition for the child of a noble to receive a Noye, a slave, as their coming of age present for their 21st birthday. Although it is only Hana Acacia's 18th birthday, her father has deemed it appropriate to grant her with the one thing she dreads the most, a Noye. Hana has lived her life categorizing everything she has ever encountered into either being beautiful or hideous - but with an exceptional twist; she doesn't judge on appearance, but instead by what each individual holds within. That is why, despite his rough hair, harsh eyes, and faded scars, Sean Ambrosia is the most beautiful thing Hana has ever laid her eyes on.

    Lawrence Hill’s new book doesn’t lessen the awfulness of the times, but adds a unique human dimension. Hill has created an uplifting and highly educational story about a shameful part of history. The Book of Negroes is sold in the United States under the title, Someone Knows My Name. Aminata Diallo was born free in Africa in the eighteenth century. She had a rich and lovely childhood until the day she was captured by slave traders and marched off to the coast in chains. Along with thousands of others, Aminata was destined for North America as a slave to white owners. She was eleven years old. Hill tracks Aminata’s story through the circle of her life. Every Bookclub-in-a-Box discussion guide includes complete coverage of the themes and symbols, writing style, and interesting background information on the novel and the author.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.