Ours is a time of revolutionary change that has no precedent in history. With the same passion he brought to the challenge of climate change, and with his decades of experience on the front lines of global policy, Al Gore surveys our planet’s beclouded horizon and offers a sober, learned, and ultimately hopeful forecast in the visionary tradition of Alvin Toffler’s Future Shock and John Naisbitt’s Megatrends. In The Future, Gore identifies the emerging forces that are reshaping our world:   • Ever-increasing economic globalization has led to the emergence of what he labels “Earth Inc.”—an integrated holistic entity with a new and different relationship to capital, labor, consumer markets, and national governments than in the past. • The worldwide digital communications, Internet, and computer revolutions have led to the emergence of “the Global Mind,” which links the thoughts and feelings of billions of people and connects intelligent machines, robots, ubiquitous sensors, and databases. • The balance of global political, economic, and military power is shifting more profoundly than at any time in the last five hundred years—from a U.S.-centered system to one with multiple emerging centers of power, from nation-states to private actors, and from political systems to markets. • A deeply flawed economic compass is leading us to unsustainable growth in consumption, pollution flows, and depletion of the planet’s strategic resources of topsoil, freshwater, and living species. • Genomic, biotechnology, neuroscience, and life sciences revolutions are radically transforming the fields of medicine, agriculture, and molecular science—and are putting control of evolution in human hands. • There has been a radical disruption of the relationship between human beings and the earth’s ecosystems, along with the beginning of a revolutionary transformation of energy systems, agriculture, transportation, and construction worldwide.   From his earliest days in public life, Al Gore has been warning us of the promise and peril of emergent truths—no matter how “inconvenient” they may seem to be. As absorbing as it is visionary, The Future is a map of the world to come, from a man who has looked ahead before and been proven all too right.Praise for The Future “Magisterial . . . The passion is unmistakable. So is the knowledge. Practically every page offers an illumination.”—Bloomberg   “In The Future . . . Gore takes on a subject whose scale matches that of his achievements and ambition.”—The New York Times Book Review  “Historically grounded . . . Gore’s strengths lie in his passion for the subject and in his ability to take the long view by putting current events and trends in historical context.”—Publishers Weekly   “Provocative, smart, densely argued . . . a tour de force of Big Picture thinking.”—Kirkus Reviews (starred review)   “A luminously intelligent analysis that is packed with arresting ideas and facts.”—The Guardian

    Close worked desperately to contain the outbreak. Haunted by this wrenching crisis, Dr. Close felt compelled to honor the memory of the courageous people he knew and lost. This is their story: a terrifying, completely authentic novel that begins with an invisible killer.  It strikes without warning—a lethal disease with no name . . . and no cure.   At a Catholic mission in Yambuku, a remote village sixty miles south of the Ebola River, local teacher Mabalo Lokela visits the clinic with a raging fever. Sister Lucie, a Flemish nun and nurse, gives him a shot of an antimalarial drug, wipes off the syringe, and awaits her next patient. Within days, Mabalo is dead. Soon, others are falling ill. Less than three weeks later, the virus claims Sister Lucie’s life as well. Panic erupts, but as the villagers attempt to flee, all roads leading out of Yambuku are closed off, the dying forced back. And as the single radio connecting the mission to the outside world brings only bad news, the valiant nuns and medical personnel left behind have no choice but to pray, and wonder: Will they survive long enough for help to arrive?

    Turn to any page, and you'll find essential point-of-care guidance on all the major conditions seen in clinical medicine. Completely updated to reflect all the major advances and new clinical developments, the new edition of the Manual is the most indispensable yet. It continues to focus on diagnosis and therapy with an emphasis on patient care and offers authoritative, high-yield coverage of: Etiology and epidemiology Clinically relevant pathophysiology Signs & Symptoms o Differential Diagnosis Physical and Laboratory Findings Therapeutics o Practice GuidelinesNEW FEATURESFull-color presentation for the first time!Full-color images of clinical conditions encountered in dermatology, cardiology, and eye diseases New chapters on end-of-life care, congenital heart disease in the adult patient, non-invasive cardiac examination, and metabolic syndromeLook for these other great Harrison's titles:Harrison's Principles of Internal Medicine, 17eHarrison's Online available through Accessmedicine.com

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?

    Now, in Head Strong, Asprey shows readers how to biohack their way to a sharper, smarter, faster, more resilient brain.Imagine feeling like your mind is operating at its clearest and sharpest, and being able—possibly for the first time in your life—to do more in less time? What it suddenly became easier to do the very hardest things you do? Or if you could feel 100% confident about your intellect, and never again fear being the person in the room who just isn’t smart enough, or can’t remember something important? How would you treat people if the mood swings, short temper, and food cravings that disrupt your day could simply disappear?In Head Strong, Asprey shows us that all of this is possible—and more. Using his simple lifestyle modifications (or "hacks") to take advantage of how the structure of your brain works, readers will learn how to take their mental performance to the next level. Combining the latest findings in neuroscience and neurobiology with a hacker-inspired "get it done now" perspective, Asprey offers a program structured around key areas of brain performance that will help you:Power the brain with exactly what it needs to perform at its best all day longEliminate the sources of "kryptonite," both nutritional and environmental, that make the brain slower.Supercharge the cellular powerhouses of our brains, the mitochondria, to eliminate cravings and turn up mental focus.Reverse inflammation to perform better right now, then stay sharp and energized well into your golden years.Promote neuron growth to enhance processing speed and reinforce new learning—hotwiring your brain for success.Asprey’s easy to follow, two-week program offers a detailed plan to supercharge brain performance, including: which foods to eat and which ones to avoid, how to incorporate the right kinds of physical activity into your day, a detox protocol for your home and body; meditation and breathing for performance, recommended brain-boosting supplements; and how to adjust the lighting in your home and work space to give your brain the quality light it thrives on.A better brain—and a happier, easier, more productive life—is within reach. You just need to get Head Strong.

    . . when it comes to the legacy of this country's war on drugs, we should all share his outrage." --The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy lifeDr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a colleague, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism.Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars.Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

    Understand how to use groundbreaking science to improve your health, mood, and more.In just the last few years, scientists have shown how the microscopic ecosystem within our bodies—particularly within our intestines—has an astonishing impact on our lives. Pioneering scientist Rob Knight and award-winning science journalist Brendan Buhler explain—with humor and witty metaphors—why these new findings matters to everyone.You are mostly not you. The human gut is host to trillions of microbes, and evidence shows that small changes in these microbes present (altered by antibiotics, diet, geographic region, and so on) may affect weight, likelihood of disease, and even psychological factors like risk-taking behavior. The evidence for their influence is astonishing. Rob Knight is one of the key figures driving forward this new science. His work demonstrates the startling connection between the presence of certain harmless bacteria and the health benefits we all seek for ourselves and our children.In Follow Your Gut, Knight pairs with Brendan Buhler, an award-winning science writer, to explore the previously unseen world inside our bodies. With a practical eye toward deeper knowledge and better decisions, they lead a detailed tour of our microbiome as well as an exploration of the known effects of antibiotics, probiotics, diet choices, birth method, and access to livestock on our children's lifelong health. Ultimately, this pioneering book explains how to learn about your own micro biome and take steps toward understanding and improving your health, using the latest research as a guide.

    The good news is that social connection is innate and a cure for loneliness. In Together, the former Surgeon General will address the importance of community and connection and offer viable and actionable solutions to this overlooked epidemic.

    Garrett also exposes the ungoverned world of biological terrorism.

     With rivalries, reversals, and a race against time, the struggle to eradicate polio is one of the great tales of modern history. It begins with the birth of Jonas Salk, shortly before one of the worst polio epidemics in United States history. At the time, the disease was a terrifying enigma: striking from out of nowhere, it afflicted tens of thousands of children in this country each year and left them-literally overnight-paralyzed, and sometimes at death's door. Salk was in medical school just as a president crippled by the disease, Franklin D. Roosevelt, was taking office-and providing the impetus to the drive for studies on polio. By the early 1950s, Salk had already helped create an influenza vaccine, and was hot on the trail of the polio virus. He was nearly thwarted, though, by the politics of medicine and by a rival researcher eager to discredit his proposed solution. Meanwhile, in 1952, polio was spreading in record numbers, with 57,000 cases in the United States that summer alone. In early 1954, Salk was weighing the possibility of trials of a not-yet-perfected vaccine against-as the summer approached-the prospect of thousands more children being struck down by the disease. The results of the history-making trials were announced at a press conference on April 12, 1955: "The vaccine works." The room-and an entire nation-erupted in cheers for this singular medical achievement. Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program-and as humanity is tantalizingly close to eradicating polio worldwide-comes this unforgettable chronicle. Salk's work was an unparalleled achievement-and it makes for a magnificent read.

    Women crave intimacy and emotional connection. Women don't want sex with strangers. Right? Wrong. Could 'the fairer sex' in fact be more sexually aggressive and anarchic than men? In What Do Women Want? Adventures in the Science of Female Desire, critically acclaimed journalist Daniel Bergner looks at the evidence. Recent research, he finds, dismantles the myths to reveal an unprecedented portrait of female lust- the triggers, the fantasies, the mind-body connection (and disconnection), the reasons behind the loss of libido and, most revelatory, that this loss is not inevitable.

    But as risk expert Gerd Gigerenzer shows, the surprising truth is that in the real world, we often get better results by using simple rules and considering less information. In Risk Savvy, Gigerenzer reveals that most of us, including doctors, lawyers, financial advisers, and elected officials, misunderstand statistics much more often than we think, leaving us not only misinformed, but vulnerable to exploitation. Yet there is hope. Anyone can learn to make better decisions for their health, finances, family, and business without needing to consult an expert or a super computer, and Gigerenzer shows us how.Risk Savvy is an insightful and easy-to-understand remedy to our collective information overload and an essential guide to making smart, confident decisions in the face of uncertainty.

    We like to think that we are in control of the future of "artificial" intelligence. The reality, though, is that we -- the everyday people whose data powers AI -- aren't actually in control of anything. When, for example, we speak with Alexa, we contribute that data to a system we can't see and have no input into -- one largely free from regulation or oversight. The big nine corporations -- Amazon, Google, Facebook, Tencent, Baidu, Alibaba, Microsoft, IBM and Apple--are the new gods of AI and are short-changing our futures to reap immediate financial gain. In this book, Amy Webb reveals the pervasive, invisible ways in which the foundations of AI -- the people working on the system, their motivations, the technology itself -- is broken. Within our lifetimes, AI will, by design, begin to behave unpredictably, thinking and acting in ways which defy human logic. The big nine corporations may be inadvertently building and enabling vast arrays of intelligent systems that don't share our motivations, desires, or hopes for the future of humanity. Much more than a passionate, human-centered call-to-arms, this book delivers a strategy for changing course, and provides a path for liberating us from algorithmic decision-makers and powerful corporations.

    Social networks surrender their original missions to more immediately profitable data mining, while brokerage houses abandon value investing for algorithms that drain markets and our 401ks alike--all tactics driven by the need to stoke growth by any means necessary. Instead of taking this opportunity to reprogram our economy for sustainability, we have doubled down on growth as its core command. We have reached the limits of this approach. We must escape the growth trap, once and for all. Media scholar and technology author Douglas Rushkoff--one of today's most original and influential thinkers--argues for a new economic program that utilizes the unique distributive power of the internet while breaking free of the winner-take-all system the growth trap leaves in its wake. Drawing on sources both contemporary and historical, Rushkoff pioneers a new understanding of the old economic paradigm, from central currency to debt to corporations and labor.Most importantly, he offers a series of practical steps for businesses, consumers, investors, and policymakers to remake the economic operating system from the inside out--and prosper along the way. Instead of boycotting Wal-Mart or overtaxing the wealthy, we simply implement strategies that foster the creation of value by stakeholders other than just ourselves. From our currency to our labor to the corporation, every aspect of the economy can be reprogrammed with minimal disruption to create a more equitably distributed prosperity for all.Inspiring and challenging, Throwing Rocks at the Google Bus provides a pragmatic, optimistic, and human-centered model for economic progress in the digital age.