But we should--even those of us who take care of our business in pristine, sanitary conditions. For it's not only in developing countries that human waste is a major public health threat: population growth is taxing even the most advanced sewage systems, and the disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, 1.95 million people have no access to an indoor toilet. Yet the subject remains unmentionable."The Big Necessity "takes aim at the taboo, revealing everything that matters about how people do--and don't--deal with their own waste. Moving from the deep underground sewers of Paris, London, and New York--an infrastructure disaster waiting to happen--to an Indian slum where ten toilets are shared by 60,000 people, Rose George stops along the way to explore the potential saviors: China's five million biogas digesters, which produce energy from waste; the heroes of third world sanitation movements; the inventor of the humble Car Loo; and the U.S. Army's personal lasers used by soldiers to zap their feces in the field.With razor-sharp wit and crusading urgency, mixing levity with gravity, Rose George has turned the subject we like to avoid into a cause with the most serious of consequences.

    Mysteries don't lose their poetry because they are solved: the solution often is more beautiful than the puzzle, uncovering deeper mysteries. With the wit, insight, and spellbinding prose that have made him a best-selling author, Dawkins takes up the most important and compelling topics in modern science, from astronomy and genetics to language and virtual reality, combining them in a landmark statement of the human appetite for wonder. This is the book Richard Dawkins was meant to write: a brilliant assessment of what science is (and isn't), a tribute to science not because it is useful but because it is uplifting.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    If such a plague returned today, taking a comparable percentage of the U.S. population with it, 1.5 million Americans would die.The fascinating, true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for "The New York Times," unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

    In The Ends of the World, Peter Brannen dives into deep time, exploring Earth’s past dead ends, and in the process, offers us a glimpse of our possible future.Many scientists now believe that the climate shifts of the twenty-first century have analogs in these five extinctions. Using the visible clues these devastations have left behind in the fossil record, The Ends of the World takes us inside “scenes of the crime,” from South Africa to the New York Palisades, to tell the story of each extinction. Brannen examines the fossil record—which is rife with creatures like dragonflies the size of sea gulls and guillotine-mouthed fish—and introduces us to the researchers on the front lines who, using the forensic tools of modern science, are piecing together what really happened at the crime scenes of the Earth’s biggest whodunits.Part road trip, part history, and part cautionary tale, The Ends of the World takes us on a tour of the ways that our planet has clawed itself back from the grave, and casts our future in a completely new light.

    From the bestselling author of The Man Who Mistook His Wife for a Hat and An Anthropologist on Mars comes "a delightful inner and outer journey, destined to surprise and please the devoted Sacks reader" (Washington Post) - a work rich in curiosity and compassion and intellectual adventure.

     "The genius of Hanson's fascinating, inspiring, and entertaining book stems from the fact that it is not about how all kinds of things grow from seeds; it is about the seeds themselves." -- Mark Kurlansky, New York Times Book Review We live in a world of seeds. From our morning toast to the cotton in our clothes, they are quite literally the stuff and staff of life: supporting diets, economies, and civilizations around the globe. Just as the search for nutmeg and pepper drove the Age of Discovery, coffee beans fueled the Enlightenment and cottonseed sparked the Industrial Revolution. Seeds are fundamental objects of beauty, evolutionary wonders, and simple fascinations. Yet, despite their importance, seeds are often seen as commonplace, their extraordinary natural and human histories overlooked. Thanks to this stunning new book, they can be overlooked no more. This is a book of knowledge, adventure, and wonder, spun by an award-winning writer with both the charm of a fireside story-teller and the hard-won expertise of a field biologist. A fascinating scientific adventure, it is essential reading for anyone who loves to see a plant grow.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.

    News of both the Ice Man's discovery and his age, which was put at over five thousand years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative of a man who died thousands of years ago?In The Seven Daughters of Eve, he gives us a firsthand account of his research into a remarkable gene, which passes undiluted from generation to generation through the maternal line. After plotting thousands of DNA sequences from all over the world, Sykes found that they clustered around a handful of distinct groups. Among Europeans and North American Caucasians, there are, in fact, only seven. This conclusion was staggering: almost everyone of native European descent, wherever they may live throughout the world, can trace their ancestry back to one of seven women, the Seven Daughters of Eve.Naming them Ursula, Xenia, Helena, Velda, Tara, Katrine, and Jasmine, Sykes has created portraits of their disparate worlds by mapping the migratory patterns followed by millions of their ancestors. In reading the stories of these seven women, we learn exactly how our origins can be traced, how and where our ancient genetic ancestors lived, and how we are each living proof of the almost indestructible strands of DNA, which have survived over so many thousands of years. Indeed, The Seven Daughters of Eve is filled with dramatic stories: from Sykes's identification, using DNA samples from two living relatives, of the remains of Tsar Nicholas and Tsaress Alexandra, to the Caribbean woman whose family had been sold into slavery centuries before and whose ancestry Sykes was able to trace back to the Eastern coast of central Africa. Ultimately, Sykes's investigation reveals that, as a race, what humans have in common is more deeply embedded than what separates us.

    Here is a delightfully entertaining and enlightening look at the unique sex lives of humans.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    Full of extraordinary facts and astonishing stories, The Body: A Guide for Occupants is a brilliant, often very funny attempt to understand the miracle of our physical and neurological make up.A wonderful successor to A Short History of Nearly Everything, this book will have you marvelling at the form you occupy, and celebrating the genius of your existence, time and time again.

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    You’ve had a martini or three, and you mingle through the crowd, wondering how long you need to stay before going out for pizza. Suddenly you’re introduced to someone new, Dr. Nice Tomeetya. You forget the pizza. Now is the perfect time to bring up all those strange questions you’d like to ask during an office visit with your own doctor but haven’t had the guts (or more likely the time) to do so. You’re filled with liquid courage . . . now is your chance! If you’ve ever wanted to ask a doctor . . .•How do people in wheelchairs have sex?•Why do I get a killer headache when I suck down my milkshake too fast?•Can I lose my contact lens inside my head forever?•Why does asparagus make my pee smell?•Why do old people grow hair on their ears?•Is the old adage “beer before liquor, never sicker, liquor before beer . . .” really true? . . . then Why Do Men Have Nipples? is the book for you.Compiled by Billy Goldberg, an emergency medicine physician, and Mark Leyner, bestselling author and well-known satirist, Why Do Men Have Nipples? offers real factual and really funny answers to some of the big questions about the oddities of our bodies.