This is the story of a fateful year that prefigured the events of 1776.In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protegee; Samuel Adams.During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. Inoculation led to vaccination, one of the most profound medical discoveries in history. Public outrage forced Boylston into hiding, and Mather's house was firebombed.A political fever also raged. Elisha Cooke was challenging the Crown for control of the colony and finally forced Royal Governor Samuel Shute to flee Massachusetts. Samuel Adams and the Patriots would build on this to resist the British in the run-up to the American Revolution. And a bold young printer James Franklin (who was on the wrong side of the controversy on inoculation), launched America's first independent newspaper and landed in jail. His teenage brother and apprentice, Benjamin Franklin, however, learned his trade in James' shop and became a father of the Independence movement.One by one, the atmosphere in Boston in 1721 simmered and ultimately boiled over, leading to the full drama of the American Revolution.

    And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

    Dr. Manheimer describes the plights of twelve very different patients--from dignitaries at the nearby UN, to supermax prisoners at Riker's Island, to illegal immigrants, and Wall Street tycoons.Manheimer was not only the medical director of the country's oldest public hospital for over 13 years, but he was also a patient. As the book unfolds, the narrator is diagnosed with cancer, and he is forced to wrestle with the end of his own life even as he struggles to save the lives of others.

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    Here is the sweeping story of a substance that has been feared, revered, mythologized, and used in magic and medicine from earliest times--a substance that has become the center of a huge, secretive, and often dangerous worldwide commerce.Winner of the Los Angeles Times Book Prize, Blood was described by judges as "a gripping page-turner, a significant contribution to the history of medicine and technology and a cautionary tale. Meticulously reported and exhaustively documented."

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    He begins with Copernicus, during the Renaissance, when science replaced mysticism as a means of explaining the workings of the world, and he continues through the centuries, creating an unbroken genealogy of not only the greatest but also the more obscure names of Western science, a dot-to-dot line linking amateur to genius, and accidental discovery to brilliant deduction.By focusing on the scientists themselves, Gribbin has written an anecdotal narrative enlivened with stories of personal drama, success and failure. A bestselling science writer with an international reputation, Gribbin is among the few authors who could even attempt a work of this magnitude. Praised as “a sequence of witty, information-packed tales” and “a terrifi c read” by The Times upon its recent British publication, The Scientists breathes new life into such venerable icons as Galileo, Isaac Newton, Albert Einstein and Linus Pauling, as well as lesser lights whose stories have been undeservedly neglected. Filled with pioneers, visionaries, eccentrics and madmen, this is the history of science as it has never been told before.From the Hardcover edition.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself.Of all diseases, the 1918 flu was by far the worst that has ever afflicted humankind; not even the Black Death of the Middle Ages comes close in terms of the number of lives it took. No war, no natural disaster, no famine has claimed so many. In the space of eighteen months in 1918-1919, about 500 million people--one-third of the global population at the time--came down with influenza. The exact total of lives lost will never be known, but the best estimate is between 50 and 100 million. In this powerful book, filled with black and white photographs, nonfiction master Albert Marrin examines the history, science, and impact of this great scourge--and the possibility for another worldwide pandemic today.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    After the Ice is the story of this momentous period--one in which a seemingly minor alteration in temperature could presage anything from the spread of lush woodland to the coming of apocalyptic floods--and one in which we find the origins of civilization itself.Drawing on the latest research in archaeology, human genetics, and environmental science, After the Ice takes the reader on a sweeping tour of 15,000 years of human history. Steven Mithen brings this world to life through the eyes of an imaginary modern traveler--John Lubbock, namesake of the great Victorian polymath and author of Prehistoric Times. With Lubbock, readers visit and observe communities and landscapes, experiencing prehistoric life--from aboriginal hunting parties in Tasmania, to the corralling of wild sheep in the central Sahara, to the efforts of the Guila Naquitz people in Oaxaca to combat drought with agricultural innovations.Part history, part science, part time travel, After the Ice offers an evocative and uniquely compelling portrayal of diverse cultures, lives, and landscapes that laid the foundations of the modern world.

    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

    Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.