Would you know one if you held it in your hand?In Dark Archives, Megan Rosenbloom seeks out the historic and scientific truths behind anthropodermic bibliopegy--the practice of binding books in this most intimate covering. Dozens of such books live on in the world's most famous libraries and museums. Dark Archives exhumes their origins and brings to life the doctors, murderers, innocents, and indigents whose lives are sewn together in this disquieting collection. Along the way, Rosenbloom tells the story of how her team of scientists, curators, and librarians test rumored anthropodermic books, untangling the myths around their creation and reckoning with the ethics of their custodianship.A librarian and journalist, Rosenbloom is a member of The Order of the Good Death and a cofounder of their Death Salon, a community that encourages conversations, scholarship, and art about mortality and mourning. In Dark Archives--captivating and macabre in all the right ways--she has crafted a narrative that is equal parts detective work, academic intrigue, history, and medical curiosity: a book as rare and thrilling as its subject.

    When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water, turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.' Dr Ben Goldacre is the author of the Bad Science column in the Guardian. His book is about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads.

    It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections - all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world.Relive the heartwarming true story of the discovery of insulin as it's never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others.

    There is evidence from the archaeological record that Mycobacterium tuberculosis and its human hosts have been together for a very long time. The very mention of tuberculosis brings to mind romantic images of great literary figures pouring out their souls in creative works as their bodies were being decimated by consumption. It is a disease that at various times has had a certain glamour associated with it.From the medieval period to the modern day, Helen Bynum explores the history and development of tuberculosis throughout the world, touching on the various discoveries that have emerged about the disease over time, and focusing on the experimental approaches of Rene Laennec (1781-1826) and Robert Koch (1842-1910). Bynum also examines the place tuberculosis holds in the popular imagination and its role in various forms of the dramatic arts.The story of tuberculosis since the 1950s is complex, and Bynum describes the picture emerging from the World Health Organization of the difficulties that attended the management of the disease in the developing world. In the meantime, tuberculosis has emerged again in the West, both among the urban underclass and in association with a new infection - HIV. The disease has returned with a vengeance - in drug-resistant form. The story of tuberculosis is far from over.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    Fearful that plutonium  might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in  hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them.Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance.From the Hardcover edition.

    She reveals them to be curious, clever connoisseurs of their world, technologically inventive and ecologically adaptable. Above all, they were successful survivors for more than 300,000 years, during times of massive climatic upheaval.At a time when our species has never faced greater threats, we’re obsessed with what makes us special. But, much of what defines us was also in Neanderthals, and their DNA is still inside us. Planning, co-operation, altruism, craftsmanship, aesthetic sense, imagination... perhaps even a desire for transcendence beyond mortality.It is only by understanding them, that we can truly understand ourselves.

    A city of gas lamps, cobblestone streets, and horse-drawn carriages—and home to the controversial surgeon Dr. Spencer Black. The son of a grave robber, young Dr. Black studies at Philadelphia’s esteemed Academy of Medicine, where he develops an unconventional hypothesis: What if the world’s most celebrated mythological beasts—mermaids, minotaurs, and satyrs—were in fact the evolutionary ancestors of humankind?  The Resurrectionist offers two extraordinary books in one. The first is a fictional biography of Dr. Spencer Black, from a childhood spent exhuming corpses through his medical training, his travels with carnivals, and the mysterious disappearance at the end of his life. The second book is Black’s magnum opus: The Codex Extinct Animalia, a Gray’s Anatomy for mythological beasts—dragons, centaurs, Pegasus, Cerberus—all rendered in meticulously detailed anatomical illustrations. You need only look at these images to realize they are the work of a madman. The Resurrectionist tells his story.

    He regales us with stories of spontaneous human combustion; vicious tribes of tailed men; the Two-Headed Boy of Bengal; Mary Toft, who allegedly gave birth to seventeen rabbits; and Julia Pastrana, exhibited around the world as the Ape Woman. Bondeson combines an historian's skill in showing us our timeless fascination with the grotesque with a physician's diagnostic abilities, as he examines the evidence and provides likely explanations for these peculiar events.

    Intriguingly fascinating and entertaining reading for anyone who is interested in how society copes with catastrophe and pain. Relevant today in face of the worldwide medical calamity of AIDS. Continuously in print since its first publication in 1934, with over 75 printings.

    A killer with little respect for class or wealth, cholera ravaged the squalid streets of Soho and rocked the great centers of Victorian power. In this gripping book, Sandra Hempel tells the story of John Snow, a reclusive doctor without money or social position, who—alone and unrecognized—had the genius to look beyond the conventional wisdom of his day and uncover the truth behind the pandemic. She describes how Snow discovered that cholera was spread through drinking water and how this subsequently laid the foundations for the modern, scientific investigation of today's fatal plagues. A dramatic account with a colorful cast of characters, The Strange Case of the Broad Street Pump features diversions into fascinating facets of medical and social history, such as Snow's tending of Queen Victoria in childbirth, Dutch microbiologist Leeuwenhoek's deliberate breeding of lice in his socks, Dickensian children's farms, and riotous nineteenth-century anesthesia parties. An afterword discusses the new threat of infectious diseases—including malaria, yellow fever, and cholera—with today's global warming. Copub: Granta

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    Based on selective breeding of human beings, eugenics began in laboratories on Long Island but ended in the concentration camps of Nazi Germany. Cruel and racist laws were enacted in 27 U.S. states, while the supporters of eugenics included progressive thinkers like Woodrow Wilson, Margaret Sanger and Oliver Wendell Holmes. Ultimately, over 60,000 "unfit" Americans were coercively sterilized, a third of them after Nuremberg had declared such practices crimes against humanity. This is a timely and shocking chronicle of bad science at its worst—with many important lessons for the genetic age in which an interest in eugenics has been dangerously revived.