Leeuwenhoek proceeded to examine the microscopic activity of his spittle, teeth plaque, and feces, and as the result of his findings the field of bacteriology was born. Some two hundred years later, Wilhelm Conrad Roentgen, a professor of theoretical physics at the University of Wurzburg, invited his wife to his laboratory, asked her to place her hand on an unexposed photographic plate, turned on an electric current, and showed this terrified woman a picture of the bones of her hand. And so came the discovery of the X-ray.This absorbing book is the first to describe these and eight other monumental medical discoveries throughout history, bringing to life the scientific pioneers responsible for them and the excitement, frustrations, and jealousies that surrounded the final achievements. Two distinguished physicians, Meyer Friedman and Gerald W. Friedland, have drawn on their many years of experience as well as on that of world-renowned antiquarian book dealers, physician collectors of old and new medical publications, and medical school professors to single out these medical breakthroughs from thousands of candidates, and, in several cases, to provide information never before available. Their engrossing stories of the ten most significant discoveries will be read with enjoyment by anyone fascinated by the mysteries of medicine.

    Moving up the Mississippi River in the late summer, in the span of just a few months the fever killed more than eighteen thousand people. The city of Memphis, Tennessee, was particularly hard hit: Of the approximately twenty thousand who didn’t flee the city, seventeen thousand contracted the fever, and more than five thousand died—the equivalent of a million New Yorkers dying in an epidemic today.Fever Season chronicles the drama in Memphis from the outbreak in August until the disease ran its course in late October. The story that Jeanette Keith uncovered is a profound–and never more relevant–account of how a catastrophe inspired reactions both heroic and cowardly. Some ministers, politicians, and police fled their constituents, while prostitutes and the poor risked their lives to nurse the sick. Using the vivid, anguished accounts and diaries of those who chose to stay and those who were left behind, Fever Season depicts the events of that summer and fall. In its pages we meet people of great courage and compassion, many of whom died for having those virtues. We also learn how a disaster can shape the future of a city.

    Starting in Paris, Jean-Baptiste-Joseph Delambre would make his way north to Dunkirk, while Pierre-François-André Méchain voyaged south to Barcelona. Their mission was to measure the world, and their findings would help define the meter as one ten-millionth of the distance between the pole and the equator-- a standard that would be used for all people, for all time. "The Measure of All Things" is the astonishing tale of one of history's greatest scientific adventures. Yet behind the public triumph of the metric system lies a secret error, one that is perpetuated in every subsequent definition of the meter. As acclaimed historian and novelist Ken Alder discovered through his research, there were only two people on the planet who knew the full extent of this error: Delambre and Méchain themselves. By turns a science history, detective tale, and human drama, "The Measure of All Things" describes a quest that succeeded as it failed, and continues to enlighten and inspire to this day.

    Part autobiography, part mystery, the story is told by a man who was one of the architects of a radical vaccination scheme that became a key strategy in ending the horrible disease when it was finally contained in India. In House on Fire, William H. Foege describes his own experiences in public health and details the remarkable program that involved people from countries around the world in pursuit of a single objective—eliminating smallpox forever. Rich with the details of everyday life, as well as a few adventures, House on Fire gives an intimate sense of what it is like to work on the ground in some of the world’s most impoverished countries—and tells what it is like to contribute to programs that really do change the world.

    Drawing vibrant connections between the colonization of whole nations, the health of the mountainsides and the abuse of individual women, children and men, Medicine Stories offers the paradigm of integrity as a political model to people who hunger for a world of justice, health and love.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    In this psychological portrait of a city in terror, J. H. Powell presents a penetrating study of human nature revealing itself. Bring Out Your Dead is an absorbing account, form the original sources, of an infamous tragedy that left its mark on all it touched.

    Diarmuid Jeffreys traces the story of aspirin from the drug's origins in ancient Egypt, through its industrial development at the end of the nineteenth century and its key role in the great flu pandemic of 1918, to its subsequent exploitation by the pharmaceutical conglomerates and the marvelous powers still being discovered today.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    Jack Geiger, M.D., New York Times Book Review

    In Elephants on Acid, Boese details the results of this scientific trial, as well as answers to the questions: Why can't people tickle themselves? Would the average dog summon help in an emergency? Will babies instinctually pick a well-balanced diet? Is it possible to restore life to the dead? Read on to find out...