Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    In Denialism, New Yorker staff writer Michael Specter reveals that Americans have come to mistrust institutions and especially the institution of science more today than ever before. For centuries, the general view had been that science is neither good nor bad—that it merely supplies information and that new information is always beneficial. Now, science is viewed as a political constituency that isn’t always in our best interest. We live in a world where the leaders of African nations prefer to let their citizens starve to death rather than import genetically modified grains. Childhood vaccines have proven to be the most effective public health measure in history, yet people march on Washington to protest their use. In the United States a growing series of studies show that dietary supplements and “natural” cures have almost no value, and often cause harm. We still spend billions of dollars on them. In hundreds of the best universities in the world, laboratories are anonymous, unmarked, and surrounded by platoons of security guards—such is the opposition to any research that includes experiments with animals. And pharmaceutical companies that just forty years ago were perhaps the most visible symbol of our remarkable advance against disease have increasingly been seen as callous corporations propelled solely by avarice and greed. As Michael Specter sees it, this amounts to a war against progress. The issues may be complex but the choices are not: Are we going to continue to embrace new technologies, along with acknowledging their limitations and threats, or are we ready to slink back into an era of magical thinking? In Denialism, Specter makes an argument for a new Enlightenment, the revival of an approach to the physical world that was stunningly effective for hundreds of years: What can be understood and reliably repeated by experiment is what nature regarded as true. Now, at the time of mankind’s greatest scientific advances—and our greatest need for them—that deal must be renewed.

    We currently see no evidence of any kind indicating that extraterrestrials exist outside of our solar system. But at this moment, millions of engineers, scientists, corporations, universities and entrepreneurs are racing to create the second intelligent species right here on planet earth. And we can see the second intelligent species coming from all directions in the form of self-driving cars, automated call centers, chess-playing and Jeopardy-playing computers that beat all human players, airport kiosks, restaurant tablet systems, etc. The frightening thing is that these robots will soon be eliminating human jobs in startling numbers. The first wave of unemployed workers is likely to be a million truck drivers who are replaced by self-driving trucks. Pilots will be eliminated soon as well. Then, as new computer vision systems come online, we will see tens of millions of workers in retail stores, fast food restaurants and construction sites replaced by robots. Unless we take steps now to change the economy, we will soon have tens of millions of workers who are unemployed and seeking welfare because they will have no other choice. Marshall Brain's new book "The Second Intelligent Species: How Humans Will Become as Irrelevant as Cockroaches" explores how the future will unfold as the second intelligent species emerges. The book answers questions like: - How will new computer vision systems affect the job market? - How many people will become unemployed by the second intelligent species? - What will happen to millions of newly unemployed workers? - How can modern society and modern economies cope with run-away unemployment caused by robots? - What will happen when the first sentient, conscious computer appears? - What moral and ethical principles will guide the second intelligent species? - Why do we see no extraterrestrials in our universe? "The Second Intelligent Species" offers a unique and fascinating look at the future of the human race, and the choices we will need to make to avoid massive unemployment and poverty worldwide as intelligent machines start eliminating millions of jobs.

    

    It will make you angry. It will amaze you with the courage of some of the people described in the book...The Autoimmune Epidemic is every bit as compelling as Upton Sinclair's The Jungle...It is also every bit as necessary as An Inconvenient Truth.... You will leave this book with no reservations about the veracity of the conclusions: put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise. The research is sound. The conclusions unassailable.... Reading The Autoimmune Epidemic is a necessary first step. Reading The Autoimmune Epidemic is a life-altering event. It needs to be."

    Syfret re-examines the meaning of worth, value, time, happiness, success, and connection, and guides us towards the alternative path of pointless pleasure.When you let go of the idea that everything must have purpose, you will find relief from stress, exhaustion, and anxiety. Most importantly, you can embrace the opportunity to enjoy the moment, the present, the chaos and luck of being alive at all. The Sunny Nihilist is an inspiring call to action and survival adaptation for modern life.

    This is our culture’s image of the perfect self. We see this person everywhere: in advertising, in the press, all over social media. We’re told that to be this person you just have to follow your dreams, that our potential is limitless, that we are the source of our own success. But this model of the perfect self can be extremely dangerous. People are suffering under the torture of this impossible fantasy. Unprecedented social pressure is leading to increases in depression and suicide. Where does this ideal come from? Why is it so powerful? Is there any way to break its spell? To answer these questions, Selfie by Will Storr takes us from the shores of Ancient Greece, through the Christian Middle Ages, to the self-esteem evangelists of 1980s California, the rise of narcissism and the selfie generation, and right up to the era of hyper-individualistic neoliberalism in which we live now. It tells the extraordinary story of the person we all know so intimately – our self.

    After all, a substantial number of decisions that we make in our everyday lives are quietly rooted in this one question: If something happened before, will it happen again? Is there such a thing as being in the zone? Can someone have a “hot hand”? Or is it simply a case of seeing patterns in randomness? Or, if streaks are possible, where can they be found?In The Hot Hand, Wall Street Journal reporter Ben Cohen offers an unfailingly entertaining and provocative investigation into these questions. He begins with how a $35,000 fine and a wild night in New York revived a debate about the existence of streaks that was several generations in the making. We learn how the ability to recognize and then bet against streaks turned a business school dropout named David Booth into a billionaire, and how the subconscious nature of streak-related bias can make the difference between life and death for asylum seekers. We see how previously unrecognized streaks hidden amidst archival data helped solve one of the most haunting mysteries of the twentieth century, the disappearance of Raoul Wallenberg. Cohen also exposes how streak-related incentives can be manipulated, from the five-syllable word that helped break arcade profit records to an arc of black paint that allowed Stephen Curry to transform from future junior high coach into the greatest three-point shooter in NBA history. Crucially, Cohen also explores why false recognition of nonexistent streaks can have cataclysmic results, particularly if you are a sugar beet farmer or the sort of gambler who likes to switch to black on the ninth spin of the roulette wheel.A brilliant investigation into when streaks exist and how they can be taken advantage of, The Hot Hand is essential reading for anyone who thinks they’ve got a shot.

    High-tech hideouts. The gratitude of the masses. Who at some point in their life hasn't dreamed of being a superhero? Impossible, right? Or is it?Possessing no supernatural powers, Batman is the most realistic of all the superheroes. His feats are achieved through rigorous training and mental discipline, and with the aid of fantastic gadgets. Drawing on his training as a neuroscientist, kinesiologist, and martial artist, E. Paul Zehr explores the question: Could a mortal ever become Batman?Zehr discusses the physical training necessary to maintain bad-guy-fighting readiness while relating the science underlying this process, from strength conditioning to the cognitive changes a person would endure in undertaking such a regimen. In probing what a real-life Batman could achieve, Zehr considers the level of punishment a consummately fit and trained person could handle, how hard and fast such a person could punch and kick, and the number of adversaries that individual could dispatch. He also tells us what it would be like to fight while wearing a batsuit and the amount of food we'd need to consume each day to maintain vigilance as Gotham City's guardian.A fun foray of escapism grounded in sound science, Becoming Batman provides the background for attaining the realizable--though extreme--level of human performance that would allow you to be a superhero.

    In a world where immediate satisfaction is the norm, it's easy to do. Whether it's decisions about our health (our chronic overuse of antibiotics has triggered a shocking rise in immunity to them), our finances (20% of us have nothing saved for retirement), or our jobs (we slash R and D to improve short-term balance sheets and then can't keep pace with competitors), we avoid mastering the skills to make smart choices about the future. Yet today more than ever, we need to understand how to make such choices--for ourselves, our families, and the world.Bina Venkataraman understands this. As a former senior advisor in the Obama administration, she led efforts to build partnerships between government and business to combat climate change, and she learned firsthand that we have forgotten how to talk about thinking ahead. Drawing from her own experience and new research in biology, psychology, economics, and beyond, she identifies the most effective ways we can learn to think clearly about long-term decisions. She explains the crucial roles that biology, the environment, and culture play in our decision-making, and she highlights the surprisingly human and achievable changes we can implement in our lives to make smarter, more thoughtful choices.The result is The Optimist's Telescope, a book brimming with useful ideas and insights into understanding how we can think about the future more clearly and make better decisions about it.

    . . a lively, engaging masterpiece."--Erik Brynjolfsson, bestselling co-author of The Second Machine AgeMIT professor Sinan Aral isn't only one of the world's leading experts on social media--he's also an entrepreneur and investor, giving him an unparalleled 360-degree view of the technology's great promise as well as its outsize capacity to damage our politics, our economy, and even our personal health.Drawing on two decades of his own research and business experience, Aral goes under the hood of the biggest, most powerful social networks to tackle the critical question of just how much social media actually shapes our choices, for better or worse. Aral shows how the tech behind social media offers the same set of behavior-influencing levers to both Russian hackers and brand marketers--to everyone who hopes to change the way we think and act--which is why its consequences affect everything from elections to business, dating to health. Along the way, he covers a wide array of topics, including how network effects fuel Twitter's and Facebook's massive growth to the neuroscience of how social media affects our brains, the real consequences of fake news, the power of social ratings, and the impact of social media on our kids.In mapping out strategies for being more thoughtful consumers of social media, The Hype Machine offers the definitive guide to understanding and harnessing for good the technology that has redefined our world overnight.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    Etcoff, a faculty member at Harvard Medical School and a practicing psychologist at Massachusetts General Hospital, skewers the enduring myth that the pursuit of beauty is a learned behavior.Etcoff puts forth that beauty is neither a cultural construction, an invention of the fashion industry, nor a backlash against feminism, but instead is in our biology. It's an essential and ineradicable part of human nature that is revered and ferociously pursued in nearly every civilizatoin--and for good reason. Those features to which we are most attracted are often signals of fertility and fecundity. When seen in the context of a Darwinian struggle for survival, our sometimes extreme attempts to attain beauty--both to become beautiful ourselves and to acquire an attractive partner--become understandable. Moreover, if we come to understand how the desire for beauty is innate, then we can begin to work in our interests, and not soley for the interests of our genetic tendencies.

    Although they incessantly hum the same nonsensical phrase ad nauseam, he can't help but think there must be some reason he alone can hear it. Now in his thirties, Krang's body is beginning to literally collapse in places, just as he discovers there may be other hearers of the constant hum. Convinced this is no coincidence, he sets out for answers, and manages to dismantle all he ever thought he knew about everything.

    Characterized by a range of new technologies that are fusing the physical, digital and biological worlds, the developments are affecting all disciplines, economies, industries and governments, and even challenging ideas about what it means to be human.Artificial intelligence is already all around us, from supercomputers, drones and virtual assistants to 3D printing, DNA sequencing, smart thermostats, wear­able sensors and microchips smaller than a grain of sand. But this is just the beginning: nanomaterials 200 times stronger than steel and a million times thinner than a strand of hair and the first transplant of a 3D printed liver are already in development. Imagine “smart factories” in which global systems of manu­facturing are coordinated virtually, or implantable mobile phones made of biosynthetic materials.The fourth industrial revolution, says Schwab, is more significant, and its ramifications more profound, than in any prior period of human history. He outlines the key technologies driving this revolution and discusses the major impacts expected on government, business, civil society and individu­als. Schwab also offers bold ideas on how to harness these changes and shape a better future—one in which technology empowers people rather than replaces them; progress serves society rather than disrupts it; and in which innovators respect moral and ethical boundaries rather than cross them. We all have the opportunity to contribute to developing new frame­works that advance progress.