As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    To find a meal, the female bolas spider releases pheromones that mimic a female moth, luring male moths into her sticky lasso web. The Glyptapanteles wasp injects a caterpillar with her young, which feed on the victim, erupt out of it, then mind-control the poor (and somehow still living) schmuck into protecting them from predators.These are among the curious critters of The Wasp That Brainwashed the Caterpillar, a jaunt through evolution’s most unbelievable, most ingenious solutions to the problems of everyday life, from trying to get laid to finding food. Join Wired science writer Matt Simon as he introduces you to the creatures that have it figured out, the ones that joust with their mustaches or choke sharks to death with snot, all in a wild struggle to survive and, of course, find true love.

    But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty. The very latest discoveries in paleontology--many of them made by the author and his students--are integrated with emerging insights from molecular biology and earth system science to forge a broad understanding of how the biological diversity that surrounds us came to be. Moving from Siberia to Namibia to the Bahamas, Knoll shows how life and environment have evolved together through Earth's history. Innovations in biology have helped shape our air and oceans, and, just as surely, environmental change has influenced the course of evolution, repeatedly closing off opportunities for some species while opening avenues for others. Readers go into the field to confront fossils, enter the lab to discern the inner workings of cells, and alight on Mars to ask how our terrestrial experience can guide exploration for life beyond our planet. Along the way, Knoll brings us up-to-date on some of science's hottest questions, from the oldest fossils and claims of life beyond the Earth to the hypothesis of global glaciation and Knoll's own unifying concept of ''permissive ecology.'' In laying bare Earth's deepest biological roots, Life on a Young Planet helps us understand our own place in the universe--and our responsibility as stewards of a world four billion years in the making.In a new preface, Knoll describes how the field has broadened and deepened in the decade since the book's original publication.

    On that day, astronomer Arthur Eddington and his team observed a solar eclipse and found something extraordinary: gravity bends light, just as Einstein predicted. The finding confirmed the theory of general relativity, fundamentally changing our understanding of space and time.A century later, another group of astronomers is performing a similar experiment on a much larger scale. The Event Horizon Telescope, a globe-spanning array of radio dishes, is examining space surrounding Sagittarius A*, the supermassive black hole at the center of the Milky Way. As Ron Cowen recounts, the foremost goal of the experiment is to determine whether Einstein was right on the details. Gravity lies at the heart of what we don't know about quantum mechanics, but tantalizing possibilities for deeper insight are offered by black holes. By observing starlight wrapping around Sagittarius A*, the telescope will not only provide the first direct view of an event horizon--a black hole's point of no return--but will also enable scientists to test Einstein's theory under the most extreme conditions.Gravity's Century shows how we got from the pivotal observations of the 1919 eclipse to the Event Horizon Telescope, and what is at stake today. Breaking down the physics in clear and approachable language, Cowen makes vivid how the quest to understand gravity is really the quest to comprehend the universe.

    Ultimately, the history of these challenges tells the story of humanity itself. Through an unforgettable cast of characters, Pulitzer Prize-winning author Richard Rhodes explains how wood gave way to coal and coal made room for oil, as we now turn to natural gas, nuclear power, and renewable energy. Rhodes looks back on five centuries of progress, through such influential figures as Queen Elizabeth I, King James I, Benjamin Franklin, Herman Melville, John D. Rockefeller, and Henry Ford. In Energy, Rhodes highlights the successes and failures that led to each breakthrough in energy production; from animal and waterpower to the steam engine, from internal-combustion to the electric motor. He addresses how we learned from such challenges, mastered their transitions, and capitalized on their opportunities. Rhodes also looks at the current energy landscape, with a focus on how wind energy is competing for dominance with cast supplies of coal and natural gas. He also addresses the specter of global warming, and a population hurtling towards ten billion by 2100. Human beings have confronted the problem of how to draw life from raw material since the beginning of time. Each invention, each discovery, each adaptation brought further challenges, and through such transformations, we arrived at where we are today. In Rhodes’s singular style, Energy details how this knowledge of our history can inform our way tomorrow.

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

    1 comes a fascinating chronicle of life’s history told not through the fossil record but through the stories of organisms that have survived, almost unchanged, throughout time. Evolution, it seems, has not completely obliterated its tracks as more advanced organisms have evolved; the history of life on earth is far older—and odder—than many of us realize.   Scattered across the globe, these remarkable plants and animals continue to mark seminal events in geological time. From a moonlit beach in Delaware, where the hardy horseshoe crab shuffles its way to a frenzy of mass mating just as it did 450 million years ago, to the dense rainforests of New Zealand, where the elusive, unprepossessing velvet worm has burrowed deep into rotting timber since before the breakup of the ancient supercontinent, to a stretch of Australian coastline with stromatolite formations that bear witness to the Precambrian dawn, the existence of these survivors offers us a tantalizing glimpse of pivotal points in evolutionary history. These are not “living fossils” but rather a handful of tenacious creatures of days long gone.   Written in buoyant, sparkling prose, Horseshoe Crabs and Velvet Worms is a marvelously captivating exploration of the world’s old-timers combining the very best of science writing with an explorer’s sense of adventure and wonder.

    Few people, however, know that research into tree rings has also made amazing contributions to our understanding of Earth's climate history and its influences on human civilization over the past 2,000 years. In her captivating new book, Tree Story, Valerie Trouet reveals how the seemingly simple and relatively familiar concept of counting tree rings has inspired far-reaching scientific breakthroughs that illuminate the complex interactions between nature and people.Trouet, a leading tree-ring scientist, takes us out into the field, from remote African villages to radioactive Russian forests, offering readers an insider's look at tree-ring research, a discipline formally known as dendrochronology. Tracing her own professional journey while exploring dendrochronology's history and applications, Trouet describes the basics of how tell-tale tree cores are collected and dated with ring-by-ring precision, explaining the unexpected and momentous insights we've gained from the resulting samples.Blending popular science, travelogue, and cultural history, Tree Story highlights exciting findings of tree-ring research, including the fate of lost pirate treasure, successful strategies for surviving California wildfire, the secret to Genghis Khan's victories, the connection between Egyptian pharaohs and volcanoes, and even the role of olives in the fall of Rome. These fascinating tales are deftly woven together to show us how dendrochronology sheds light on global climate dynamics and uncovers the clear links between humans and our leafy neighbors. Trouet delights us with her dedication to the tangible appeal of studying trees, a discipline that has taken her to austere and beautiful landscapes around the globe and has enabled scientists to solve long-pondered mysteries of Earth and its human inhabitants.

    In fact the currently accepted history of life on Earth is flawed and out of date. Now two pioneering scientists, one already an award-winning popular author, deliver an eye-opening narrative that synthesizes a generation's worth of insights from new research.Writing with zest, humor, and clarity, Ward and Kirschvink show that many of our long-held beliefs about the history of life are wrong. Three central themes emerge from the narrative. First, the development of life was not a stately, gradual process: Catastrophe, argue Ward and Kirschvink, shaped life's history more than all other forces combined-from notorious events like the sudden extinction of dinosaurs to recently discovered ones like "Snowball Earth" and the "Great Oxygenation Event." One startling possibility: that life arrived on Earth from Mars. Second, life consists of carbon, but three other molecules have determined how it evolved: oxygen, carbon dioxide, and hydrogen sulfide are carbon's silent partners. Third, ever since Darwin we have thought of evolution in terms of species. Yet it is the evolution of ecosystems-from deep-ocean vents to rainforests-that has formed the living world as we know it.Drawing on their years of experience in paleontology, biology, chemistry, and astrobiology, Ward and Kirschvink tell a story of life on Earth that is at once too fabulous to imagine and too familiar to dismiss. And in a provocative coda, they assemble discoveries from the latest cutting-edge research to imagine how the history of life might unfold deep into the future.

    The trilobites, which dominated the ocean floors for 300 million years, are gone. The last of the dinosaurs was wiped out by a Mount Everest-sized meteorite that slammed into the earth 65 million years ago. The great flying reptiles are gone, and so are the marine reptiles, some of them larger than a humpback whale. Before humans crossed the Bering land bridge some 15,000 years ago, North America was populated by mastodons, mammoths, saber-toothed tigers, and cave bears. They too are MIA. Passenger pigeons once flew over North America in flocks that numbered in the billions; the last one died in 1914.In this book you will meet creatures that were driven to extinction even more recently, as well as some that were brought back from the brink. You will even encounter animals not known to exist until recently -- an antidote to extinction.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    Here, he leads readers on an unforgettable journey into the bizarre yet oddly beautiful world of parasites. In a narrative that is by turns frightening, disgusting, and laugh-out-loud funny, Kaplan describes how drinking contaminated water can cause a three-foot-long worm to burst from your arm; how he gave birth to a parasite the size and thickness of a pencil while working in Israel; why you should never wave a dead snake in front of your privates; and why fleas are attracted to his wife. Kaplan tells stories about leeches feasting on soldiers in Vietnam; sea cucumbers with teeth in their anuses that seem to encourage the entry of symbiotic fish; the habits of parasites that cause dysentery, river blindness, and other horrifying diseases--and much, much more. Along the way, he explains the underlying science, including parasite evolution and host-parasite physiology.

    This was life—but whose?  In his most mind-bending book yet, Ball makes that disconcerting question the focus of a tour through what scientists can now do in cell biology and tissue culture. He shows how these technologies could lead to tailor-made replacement organs for when ours fail, to new medical advances for repairing damage and assisting conception, and to new ways of “growing a human.” For example, it might prove possible to turn skin cells not into neurons but into eggs and sperm, or even to turn oneself into the constituent cells of embryos. Such methods would also create new options for gene editing, with all the attendant moral dilemmas. Ball argues that such advances can therefore never be about “just the science,” because they come already surrounded by a host of social narratives, preconceptions, and prejudices. But beyond even that, these developments raise questions about identity and self, birth and death, and force us to ask how mutable the human body really is—and what forms it might take in years to come.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    C. Walton Lillehei, who, along with colleagues at University Hospital in Minneapolis and a small band of pioneers elsewhere, accomplished what many experts considered to be an impossible feat: He opened the heart, repaired fatal defects, and made the miraculous routine.Acclaimed author G. Wayne Miller draws on archival research and exclusive interviews with Lillehei and legendary pioneers such as Michael DeBakey and Christiaan Barnard, taking readers into the lives of these doctors and their patients as they progress toward their landmark achievement. In the tradition of works by Richard Rhodes and Tracy Kidder, King of Hearts tells the story of an important and gripping piece of forgotten science history.From the Hardcover edition.