As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    But when he arrived, Sherman was in such bad shape he could barely move, and his hair was coming out in clumps. Chris decided to undertake a radical rehabilitation program designed not only to heal Sherman's body but to heal his mind as well. It turns out the best way to soothe a donkey is to give it a job, and so Chris decided to teach Sherman how to run. He'd heard about burro racing--a unique type of race where humans and donkeys run together in a call-back to mining days--and decided he and Sherman would enter the World Championship in Colorado.Easier said than done. In the course of Sherman's training, Chris would have to recruit several other runners, both human and equine, and call upon the wisdom of burro racers, goat farmers, Amish running club members, and a group of irrepressible female long-haul truckers. Along the way, he shows us the life-changing power of animals, nature, and community.

    She had no relatives left, she'd lost her family farm to back taxes, and her doctor had just given her two years to live--but only if she lived restfully. He offered her a spot in the county's charity home. Instead, she decided she wanted to see the Pacific Ocean just once before she died. She bought a cast-off brown gelding named Tarzan, donned men's dungarees, loaded up her horse, and headed out from Maine in mid-November, hoping to beat the snow. She had no map, no GPS, no phone. But she had her ex-racehorse, her faithful mutt, and her own unfailing belief that Americans would treat a stranger with kindness.Between 1954 and 1956, Annie, Tarzan, and her dog, Depeche Toi, journeyed more than 4,000 miles, through America's big cities and small towns, meeting ordinary people and celebrities--from Andrew Wyeth (who sketched Tarzan) to Art Linkletter and Groucho Marx. She received many offers--a permanent home at a riding stable in New Jersey, a job at a gas station in rural Kentucky, even a marriage proposal from a Wyoming rancher who loved animals as much as she did. As Annie trudged through blizzards, forded rivers, climbed mountains, and clung to the narrow shoulder as cars whipped by her at terrifying speeds, she captured the imagination of an apprehensive Cold War America. At a time when small towns were being bypassed by Eisenhower's brand-new interstate highway system, and the reach and impact of television was just beginning to be understood, Annie and her four-footed companions inspired an outpouring of neighborliness in a rapidly changing world.

    facilities. For Hargrove, becoming an orca trainer fulfilled a childhood dream. However, as his experience with the whales deepened, Hargrove came to doubt that their needs could ever be met in captivity. When two fellow trainers were killed by orcas in marine parks, Hargrove decided that SeaWorld's wildly popular programs were both detrimental to the whales and ultimately unsafe for trainers.After leaving SeaWorld, Hargrove became one of the stars of the controversial documentary Blackfish. The outcry over the treatment of SeaWorld's orca has now expanded beyond the outlines sketched by the award-winning documentary, with Hargrove contributing his expertise to an advocacy movement that is convincing both federal and state governments to act.In Beneath the Surface, Hargrove paints a compelling portrait of these highly intelligent and social creatures, including his favorite whales Takara and her mother Kasatka, two of the most dominant orcas in SeaWorld. And he includes vibrant descriptions of the lives of orcas in the wild, contrasting their freedom in the ocean with their lives in SeaWorld.Hargrove's journey is one that humanity has just begun to take-toward the realization that the relationship between the human and animal worlds must be radically rethought.

    She moved in the most exclusive circles in Washington, D.C., rubbed elbows with big politicians, and worked on Capitol Hill. As far as she was concerned, she was changing the world. And then her mother had a heart attack. Carolyn came home to help her father with his rural medical practice in the Tennessee mountains. She'd fill in for a few days as the receptionist until her mother could return to work. Or so she thought. But days turned into weeks. Her job now included following hazmat regulations for cleaning up bodily fluids; maintaining composure when confronted with a splinter the size of a steak knife; distinguishing between a "pain," a "strain," and a "sprain" on indecipherable Medicare forms; and tending to the loquacious Miss Hiawatha, whose daily doctor visits were never billed.Eventually, Jourdan gave up her Mercedes and made do with a twenty-year-old postal jeep. She shed her suits for scrubs. And the funny thing was, she liked her new life. As she watched her father work tirelessly and uncomplainingly, she saw what making a difference really meant: being on call all hours of the day and night, tolerating the local drug addict's frequent phone calls, truly listening to Miss Hiawatha. It meant just showing up, every day, and taking care of every person in Strawberry Plains and beyond, whether he got paid to do it or not. And for his daughter, it meant learning that her real place to change the world was right here—in her hometown—by her father's side.

    It's the expose to end all exposes--the truth about the suburbs: where they planted trees and crabgrass came up, where they planted the schools and taxes came up, where they died of old age trying to merge onto the freeway and where they finally got sex out of the schools and back into the gutters.

    Solo is a cadaver dog. What started as a way to harness Solo’s unruly energy and enthusiasm soon became a calling that introduced Warren to the hidden and fascinating universe of working dogs, their handlers, and their trainers. Solo has a fine nose and knows how to use it, but he’s only one of many thousands of working dogs all over the United States and beyond. In What the Dog Knows, Warren uses her ongoing work with Solo as a way to explore a captivating field that includes cadaver dogs, drug- and bomb-detecting K9s, tracking and apprehension dogs—even dogs who can locate unmarked graves of Civil War soldiers and help find drowning victims more than two hundred feet below the surface of a lake. Working dogs’ abilities may seem magical or mysterious, but Warren shows the multifaceted science, the rigorous training, and the skilled handling that underlie the amazing abilities of dogs who work with their noses. Warren interviews cognitive psychologists, historians, medical examiners, epidemiologists, and forensic anthropologists, as well as the breeders, trainers, and handlers who work with and rely on these remarkable and adaptable animals daily. Along the way, she discovers story after story that proves the impressive capabilities—as well as the very real limits—of working dogs and their human partners. Clear-eyed and unsentimental, Warren explains why our partnership with dogs is woven into the fabric of society and why we keep finding new uses for their wonderful noses.

    Each volume of four 30-minute histories will dig into the petty name-calling and grumbling grudges that led to many of the world’s greatest advancements, all delivered with a cheeky sense of humor.Choose sides: Cope or Marsh, the jerks who discovered so many dinosaurs; Hamilton or Burr, whose rivalry fueled American politics; Queen Elizabeth or Mary Queen of Scots, who fought to rule England; Adidas or Puma, whose rivalry changed the world of sports and fashion.Kidnappings, rock fights, duels, and explosions, Rivals! shows world leaders at their absolute best and their worst, often at the same time.

    I wanted a perfect ending. Now I've learned the hard way that some poems don't rhyme, and some stories don't have a clear beginning, middle, and end."The world fondly remembers the many faces of Gilda Radner: the adamant but misinformed Emily Litella; the hyperkinetic Girl Scout Judy Miller; the irrepressibly nerdy Lisa Loopner; the gross-out queen of local network news, Rosanne Rosannadanna. A supremely funny performer, Gilda lost a long and painful struggle in May 1989 to "the most unfunny thing in the world"--cancer. But the face she showed the world during this dark time was one of great courage and hope. "It's Always Something is the story of her struggle told in Gilda's own remarkable words--a personal chronicle of strength and indomitable spirit and love undiminished by the cruel ravages of disease.This is Gilda, with whom we laughed on Saturday Night Live: warm, big-hearted, outrageous, and real. This is Gilda's last gift to us: the magnificent final performance of an incomparable entertainer whose life, though tragically brief, enriched our own lives beyond measure.

    Willie Parker grew up in the Deep South, lived in a Christian household, and converted to an even more fundamentalist form of Christianity as a young man. But upon reading an interpretation of the Good Samaritan in a sermon by Dr. Martin Luther King, Jr., he realized that in order to be a true Christian, he must show compassion for all women regardless of their needs. In 2009, he stopped practicing obstetrics to focus entirely on providing safe abortions for the women who need help the most—often women in poverty and women of color—and in the hot bed of the pro-choice debate: the South. He soon thereafter traded in his private practice and his penthouse apartment in Hawaii for the life of an itinerant abortion provider, focusing most recently on women in the Deep South. In Life’s Work, Dr. Willie Parker tells a deeply personal and thought-provoking narrative that illuminates the complex societal, political, religious, and personal realities of abortion in the United States from the unique perspective of someone who performs them and defends the right to do so every day. He also looks at how a new wave of anti-abortion activism, aimed at making incremental changes in laws and regulations state by state, are slowly chipping away at the rights of women to control their own lives. In revealing his daily battle against mandatory waiting periods and bogus rules governing the width of hallways, Dr. Parker uncovers the growing number of strings attached to the right to choose and makes a powerful Christian case for championing reproductive rights.

    Based on Crystal's one-man Broadway show of the same name, "700 Sundays"--referring sadly to the time shared by an adoring father and his devoted son--offers a heartfelt, hilarious memoir.

    . . but rarely acknowledging.Filled with insights and observations that instantly ring true—and could have come only from Nora Ephron—I Remember Nothing is pure joy.

    His journal - somewhere between Proust and Eeyore - contains apercus by Voltaire or Machiavelli cheek by jowl with hints on dealing with clumsy human feet under the dinner table, amorous interludes alongside run-ins with plumbers, and athletic diversions interspersed with joyous and trying adventures in the French countryside.Boy's reflections on life and the relationship between man and dog - and his occasional revelation about the human condition - come from a refreshingly new perspective, that is, approximately knee-height, making him an irresistible, if often irascible, companion.

    Sometimes at the risk of his own life, Leakey's love of Kenya, and his convictions about the direction his country--and all of sub-Sahara Africa--must take to survive, have been unshakeable. Wildlife Wars is the odyssey of an extraordinary man in an extraordinary land.

    Courtney Sullivan. Wry, hilarious, and profoundly genuine, this debut collection of literary essays from Sloane Crosley is a celebration of fallibility and haplessness in all their glory.From despoiling an exhibit at the Natural History Museum to provoking the ire of her first boss to siccing the cops on her mysterious neighbor, Crosley can do no right despite the best of intentions -- or perhaps because of them. Together, these essays create a startlingly funny and revealing portrait of a complex and utterly recognizable character who aims for the stars but hits the ceiling, and the inimitable city that has helped shape who she is. I Was Told There'd Be Cake introduces a strikingly original voice, chronicling the struggles and unexpected beauty of modern urban life.The pony problem --Christmas in July --The ursula cookie --Bring your machete to work day --The good people of this dimension --Bastard out of Westchester --The beauty of strangers --Fuck you, Columbus --One-night bounce --Sign language for infidels --You on a stick --Height of luxury --Smell this --Lay like broccoli --Fever faker