It was inside, inside my head, where all had become so wretchedly different. I had the night before been incontrovertibly a man of stable mood, of calm, of good cheer and unforced bonhomie. Now I had become changed, with dreadful suddenness, into another being altogether.”Simon Winchester has never shied away from big, even enormous, topics—as evidenced by his bestselling biography of the Atlantic Ocean, his account of the Krakatoa volcanic eruption, and his wildly popular “The Professor and the Madman,” about the making of the Oxford English Dictionary. In his Byliner Original “The Man with the Electrified Brain,” he takes on arguably his most daunting subject yet: his own flirtation with madness, and one of nature’s greatest and most enduring mysteries, the human brain. As a geology student in his second year at Oxford, Winchester was known as a young man of even temper and keen intellect, until one June morning when he woke to find himself “changed with dreadful suddenness into another being altogether,” his normal life “slumped into chasm” and “folded in the dirt.” For a period of nine days, he lived in immobilizing fear. Everyday items—familiar paintings, a pile of books, his own robe hanging from a hook—became objects of horror; the world lost color, purpose, all sense and safety. When the episode finally passed, he returned to normal, presuming that what had happened to him was a fluke. It wasn’t. The episode repeated itself at unpredictable and dangerous intervals for four years—always lasting for nine days—and very nearly caused the author’s death while he was on an expedition in the Arctic. What was wrong with him? Where could he find help? Would he spend the rest of his life anticipating the return of these mental blackouts? With the urgency of a whodunit, Winchester describes the coming and going of these terrifying dissociative states and the chance encounter that led to the controversial treatment of electroconvulsive therapy, which may or may not have cured him once and for all. Written by a consummate storyteller, “The Man with the Electrified Brain” locates that finest of lines between sanity and insanity and is Winchester’s most riveting and deeply personal work yet.

    A 135-mile relay race, or "ekiden" is the country's biggest annual sporting event. Thousands of professional runners compete for corporate teams in some of the most competitive races in the world. The legendary "marathon monks" run a thousand marathons in a thousand days to reach spiritual enlightenment.Yet so much of Japan's running culture remains a mystery to the outside world, on par with many of the unique aspects of contemporary Japan. Adharanand Finn, the award-winning author of Running with the Kenyans, spent six months immersed in this one of a kind running culture to discover what it might teach us about the sport and about Japan.As an amateur runner about to turn 40, he also hoped to find out whether a Japanese approach to training might help him run faster. What he learns—about competition, team work, form, chasing personal bests, and about himself—will fascinate and surprise anyone keen to explore why we run and how we might do it better.

    Worse, as they failed to cure her, they hinted that her devastating symptoms were psychological.The Lady's Handbook for Her Mysterious Illness is a memoir with a mission, to help the millions of (mostly) women who suffer from unnamed or misunderstood conditions.Ramey's pursuit of a diagnosis and cure for her own mysterious illness is a medical mystery that she says reveals a new understanding of today's chronic illnesses as ecological in nature, driven by modern changes to the basic foundations of health, from the quality of our sleep, diet, and social connection to the state of our microbiomes.

    Rana Awdish never imagined that an emergency trip to the hospital would result in hemorrhaging nearly all of her blood volume and losing her unborn first child. But after her first visit, Dr. Awdish spent months fighting for her life, enduring consecutive major surgeries and experiencing multiple overlapping organ failures. At each step of the recovery process, Awdish was faced with something even more unexpected: repeated cavalier behavior from her fellow physicians—indifference following human loss, disregard for anguish and suffering, and an exacting emotional distance.Hauntingly perceptive and beautifully written, In Shock allows the reader to transform alongside Awidsh and watch what she discovers in our carefully-cultivated, yet often misguided, standard of care. Awdish comes to understand the fatal flaws in her profession and in her own past actions as a physician while achieving, through unflinching presence, a crystalline vision of a new and better possibility for us all.As Dr. Awdish finds herself up against the same self-protective partitions she was trained to construct as a medical student and physician, she artfully illuminates the dysfunction of disconnection. Shatteringly personal, and yet wholly universal, she offers a brave road map for anyone navigating illness while presenting physicians with a new paradigm and rationale for embracing the emotional bond between doctor and patient.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    It is 4 a.m. I have run arrest calls, treated life-threatening bleeding, held the hand of a young woman dying of cancer, scuttled down miles of dim corridors wanting to sob with sheer exhaustion, forgotten to eat, forgotten to drink, drawn on every fibre of strength that I possess to keep my patients safe from harm.'How does it feel to be spat out of medical school into a world of pain, loss and trauma that you feel wholly ill-equipped to handle? To be a medical novice who makes decisions which - if you get them wrong - might forever alter, or end, a person's life?In 'Your Life in My Hands', television journalist turned junior doctor Rachel Clarke captures the extraordinary realities of life on the NHS frontline. During last year's historic junior doctor strikes, Rachel was at the forefront of the campaign against the government's imposed contract upon young doctors. Her heartfelt, deeply personal account of life as a junior doctor in today's NHS is both a powerful polemic on the degradation of Britain's most vital public institution and a love letter of optimism and hope to that same health service.

    O'Connell addresses the pervasive imposter syndrome that comes with unplanned pregnancy, the second adolescence of a changing postpartum body, the problem of sex post-baby, the weird push to make "mom friends," and the fascinating strangeness of stepping into a new, not-yet-comfortable identity. O'Connell brings us into the delivery room rendering childbirth in all its feverish gore and glory, and shattering the fantasies of a "magical" or "natural" experience that warp our expectations and erode maternal self-esteem.And Now We Have Everything is an unflinchingly frank, funny, and intimate motherhood story for our times, about needing to have a baby in order to stop being one yourself.

    On social networks and dating sites, his image and identity—a forty-year-old straight white male—had been used to hook countless women into believing in lies of love and romance. Was it all an ironic cosmic joke? Almost a decade prior, William himself had been living a lie that had lasted for more than twenty years. His secret? He was a gay man, a fact he hid from his wife and two daughters for almost as long as he had hidden it from himself.In this emotional and unflinchingly honest memoir of coming out of the closet late in life, owning up to the past, and facing the future, William Dameron confronts steroid addiction, the shame and homophobia of his childhood, the sledgehammer of secrets that slowly tore his marriage apart, and his love for a gay father of three that would once again challenge the boundaries of trust. At the true heart of The Lie is a universal story about turning self-doubt into self-acceptance and about pain, anger, and the long journey of both seeking and giving forgiveness.

    It was no wonder he gravitated to machines, which could, at least, be counted on.After fleeing his parents and dropping out of high school, his savant-like ability to visualize electronic circuits landed him a gig with KISS, for whom he created their legendary fire-breathing guitars. Later, he drifted into a “real” job, as an engineer for a major toy company. But the higher Robison rose in the company, the more he had to pretend to be “normal” and do what he simply couldn’t: communicate. It wasn’t worth the paycheck.It was not until he was forty that an insightful therapist told him he had the form of autism called Asperger’s syndrome. That understanding transformed the way Robison saw himself—and the world.Look Me in the Eye is the moving, darkly funny story of growing up with Asperger’s at a time when the diagnosis simply didn’t exist. A born storyteller, Robison takes you inside the head of a boy whom teachers and other adults regarded as “defective,” who could not avail himself of KISS’s endless supply of groupies, and who still has a peculiar aversion to using people’s given names (he calls his wife “Unit Two”). He also provides a fascinating reverse angle on the younger brother he left at the mercy of their nutty parents—the boy who would later change his name to Augusten Burroughs and write the bestselling memoir Running with Scissors.Ultimately, this is the story of Robison’s journey from his world into ours, and his new life as a husband, father, and successful small business owner—repairing his beloved high-end automobiles. It’s a strange, sly, indelible account—sometimes alien, yet always deeply human.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    Using his own research and experiences throughout the world, Lieberman recounts without jargon how and why humans evolved to walk, run, dig, and do other necessary and rewarding physical activities while avoiding needless exertion.Exercised is entertaining and enlightening but also constructive. As our increasingly sedentary lifestyles have contributed to skyrocketing rates of obesity and diseases such as diabetes, Lieberman audaciously argues that to become more active we need to do more than medicalize and commodify exercise.Drawing on insights from evolutionary biology and anthropology, Lieberman suggests how we can make exercise more enjoyable, rather than shaming and blaming people for avoiding it. He also tackles the question of whether you can exercise too much, even as he explains why exercise can reduce our vulnerability to the diseases mostly likely to make us sick and kill us.

    Paris in Love: A Memoir chronicles her joyful year in one of the most beautiful cities in the world.   With no classes to teach, no committee meetings to attend, no lawn to mow or cars to park, Eloisa revels in the ordinary pleasures of life—discovering corner museums that tourists overlook, chronicling Frenchwomen’s sartorial triumphs, walking from one end of Paris to another. She copes with her Italian husband’s notions of quality time; her two hilarious children, ages eleven and fifteen, as they navigate schools—not to mention puberty—in a foreign language; and her mother-in-law Marina’s raised eyebrow in the kitchen (even as Marina overfeeds Milo, the family dog).  Paris in Love invites the reader into the life of a most enchanting family, framed by la ville de l’amour.

    Now I’m letting my guard down.” —Hillary Rodham Clinton, from the introduction of What HappenedFor the first time, Hillary Rodham Clinton reveals what she was thinking and feeling during one of the most controversial and unpredictable presidential elections in history. Now free from the constraints of running, Hillary takes you inside the intense personal experience of becoming the first woman nominated for president by a major party in an election marked by rage, sexism, exhilarating highs and infuriating lows, stranger-than-fiction twists, Russian interference, and an opponent who broke all the rules. This is her most personal memoir yet. In these pages, she describes what it was like to run against Donald Trump, the mistakes she made, how she has coped with a shocking and devastating loss, and how she found the strength to pick herself back up afterward. With humor and candor, she tells readers what it took to get back on her feet—the rituals, relationships, and reading that got her through, and what the experience has taught her about life. She speaks about the challenges of being a strong woman in the public eye, the criticism over her voice, age, and appearance, and the double standard confronting women in politics. She lays out how the 2016 election was marked by an unprecedented assault on our democracy by a foreign adversary. By analyzing the evidence and connecting the dots, Hillary shows just how dangerous the forces are that shaped the outcome, and why Americans need to understand them to protect our values and our democracy in the future. The election of 2016 was unprecedented and historic. What Happened is the story of that campaign and its aftermath—both a deeply intimate account and a cautionary tale for the nation.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.