Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    What are America's best-loved novels? PBS will launch The Great American Read series with a 2-hour special in May 2018 revealing America's 100 best-loved novels, determined by a rigorous national survey. Subsequent episodes will air in September and October. Celebrities and everyday Americans will champion their favorite novel and in the finale in late October, America's #1 best-loved novel will be revealed. The Great American Read: The Book of Books will present all 100 novels with fascinating information about each book, author profiles, a snapshot of the novel's social relevance, film or television adaptations, other books and writings by the author, and little-known facts. Also included are themed articles about banned books, the most influential book illustrators, reading recommendations, the best first-lines in literature, and more. Beautifully designed with rare images of the original manuscripts, first-edition covers, rejection letters, and other ephemera, The Great American Read: The Book of Books is a must-have book for all booklovers.

    It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare. And it is the first complete, inside account of how President Obama persevered to push through the law, but then failed to deal with the staff incompetence and turf wars that crippled its implementation.   But by chance America’s Bitter Pill ends up being much more—because as Brill was completing this book, he had to undergo urgent open-heart surgery. Thus, this also becomes the story of how one patient who thinks he knows everything about healthcare “policy” rethinks it from a hospital gurney—and combines that insight with his brilliant reporting. The result: a surprising new vision of how we can fix American healthcare so that it stops draining the bank accounts of our families and our businesses, and the federal treasury. Praise for America’s Bitter Pill   “A tour de force . . . a comprehensive and suitably furious guide to the political landscape of American healthcare . . . persuasive, shocking.”—The New York Times   “An energetic, picaresque, narrative explanation of much of what has happened in the last seven years of health policy . . . [Brill] has pulled off something extraordinary.” —The New York Times Book Review   “A thunderous indictment of what Brill refers to as the ‘toxicity of our profiteer-dominated healthcare system.’ ”—Los Angeles Times  “A sweeping and spirited new book [that] chronicles the surprisingly juicy tale of reform.”—The Daily Beast  “One of the most important books of our time.”—Walter Isaacson   “Superb . . . Brill has achieved the seemingly impossible—written an exciting book about the American health system.”—The New York Review of Books

    In the intervening years, Herman’s volume has changed the way we think about and treat traumatic events and trauma victims. In a new afterword, Herman chronicles the incredible response the book has elicited and explains how the issues surrounding the topic have shifted within the clinical community and the culture at large. Trauma and Recovery brings a new level of understanding to a set of problems usually considered individually. Herman draws on her own cutting-edge research in domestic violence as well as on the vast literature of combat veterans and victims of political terror, to show the parallels between private terrors such as rape and public traumas such as terrorism. The book puts individual experience in a broader political frame, arguing that psychological trauma can be understood only in a social context. Meticulously documented and frequently using the victims’ own words as well as those from classic literary works and prison diaries, Trauma and Recovery is a powerful work that will continue to profoundly impact our thinking.

    We can’t stop constantly checking it on our computer screens, but what is this doing to our minds? We are never really taught how to make sense of the torrent of news we face every day, writes Alain de Botton (author of the best-selling The Architecture of Happiness), but this has a huge impact on our sense of what matters and of how we should lead our lives. In his dazzling new book, de Botton takes twenty-five archetypal news stories—including an airplane crash, a murder, a celebrity interview and a political scandal—and submits them to unusually intense analysis with a view to helping us navigate our news-soaked age. He raises such questions as Why are disaster stories often so uplifting? What makes the love lives of celebrities so interesting? Why do we enjoy watching politicians being brought down? Why are upheavals in far-off lands often so boring? In The News: A User’s Manual, de Botton has written the ultimate guide for our frenzied era, certain to bring calm, understanding and a measure of sanity to our daily (perhaps even hourly) interactions with the news machine.(With black-and-white illustrations throughout.)

    This Special Collector's Edition celebrates 100,000 copies or the book in print, and the book's on-going importance and popularity.

    This seemingly small phenomenon symbolizes a significant social change that Robert Putnam has identified in this brilliant volume, which The Economist hailed as "a prodigious achievement."Drawing on vast new data that reveal Americans' changing behavior, Putnam shows how we have become increasingly disconnected from one another and how social structures--whether they be PTA, church, or political parties--have disintegrated. Until the publication of this groundbreaking work, no one had so deftly diagnosed the harm that these broken bonds have wreaked on our physical and civic health, nor had anyone exalted their fundamental power in creating a society that is happy, healthy, and safe.Like defining works from the past, such as The Lonely Crowd and The Affluent Society, and like the works of C. Wright Mills and Betty Friedan, Putnam's Bowling Alone has identified a central crisis at the heart of our society and suggests what we can do.

    senator, in January 2005, and served as the chief official White House photographer for the President's full two terms. Souza was with President Obama more often, and at more crucial moments, than any friend or staff member, or even the First Lady--and he photographed it all. Souza captured nearly 2 million photographs of Obama, in moments ranging from classified to disarmingly candid.This large-format (12"x10"), exquisitely produced book presents more than 300 of Souza's favorite and most iconic images from these historic years; many have never been seen before. This seminal work on the Obama presidency documents moments of national importance--including the historic image of the President and his advisors watching tensely in the Situation Room as the Bin Laden mission unfolded--alongside unguarded moments with the President's family, his many encounters with children, and his time spent interacting with world leaders, members of Congress, White House staff, artists, musicians and more.The photographs are paired with captions and stories providing behind-the-scenes context for each, and offer insight into the special relationship Souza and the President forged during their time together. The result is a stunning record of a landmark era in American history.Souza's work enabled us to feel that we knew the President. This book puts us in the White House with him.

    Recently, however, serious scientists from a range of fields have been uncovering evidence that our thoughts, emotions and beliefs can ease pain, heal wounds, fend off infection and heart disease and even slow the progression of AIDS and some cancers.In Cure, award-winning science writer Jo Marchant travels the world to meet the physicians, patients and researchers on the cutting edge of this new world of medicine. We learn how meditation protects against depression and dementia, how social connections increase life expectancy and how patients who feel cared for recover from surgery faster. We meet Iraq war veterans who are using a virtual arctic world to treat their burns and children whose ADHD is kept under control with half the normal dose of medication. We watch as a transplant patient uses the smell of lavender to calm his hostile immune system and an Olympic runner shaves vital seconds off his time through mind-power alone.Drawing on the very latest research, Marchant explores the vast potential of the mind's ability to heal, lays out its limitations and explains how we can make use of the findings in our own lives. With clarity and compassion, Cure points the way towards a system of medicine that treats us not simply as bodies but as human beings.

    . . Patterns of Culture is a signpost on the road to a freer and more tolerant life." -- New York TimesA remarkable introduction to cultural studies, Patterns of Culture is an eloquent declaration of the role of culture in shaping human life. In this fascinating work, the renowned anthropologist Ruth Benedict compares three societies -- the Zuni of the southwestern United States, the Kwakiutl of western Canada, and the Dobuans of Melanesia -- and demonstrates the diversity of behaviors in them. Benedict's groundbreaking study shows that a unique configuration of traits defines each human culture and she examines the relationship between culture and the individual. Featuring prefatory remarks by Franz Boas, Margaret Mead, and Louise Lamphere, this provocative work ultimately explores what it means to be human."That today the modern world is on such easy terms with the concept of culture . . . is in very great part due to this book." -- Margaret Mead"Benedict's Patterns of Culture is a foundational text in teaching us the value of diversity. Her hope for the future still has resonance in the twenty-first century: that recognition of cultural relativity will create an appreciation for 'the coexisting and equally valid patterns of life which mankind has created for itself from the raw materials of existence.'" -- from the new foreword by Louise Lamphere, past president of the American Anthrolopological AssociationRuth Benedict (1887-1948) was one of the most eminent anthropologists of the twentieth century. Her profoundly influential books Patterns of Culture and The Chrysanthemum and the Sword: Patterns of Japanese Culture were bestsellers when they were first published, and they have remained indispensable works for the study of culture in the many decades since.

    The Clash of Civilizations and the Remaking of World Order is one of the most important books to have emerged since the end of the Cold War." --HENRY A. KISSINGERBased on the author's seminal article in Foreign Affairs, Samuel P. Huntington's The Clash of Civilizations and the Remaking of World Order is a provocative and prescient analysis of the state of world politics after the fall of communism. In this incisive work, the renowned political scientist explains how "civilizations" have replaced nations and ideologies as the driving force in global politics today and offers a brilliant analysis of the current climate and future possibilities of our world's volatile political culture."An intellectual tour de force: bold, imaginative, and provocative. A seminal work that will revolutionize our understanding of international affairs." --ZBIGNIEW BRZEZINSKI"The book is studded with insights, flashes of rare brilliance, great learning, and in particular, an ability to see the familiar in a new and provocative way." --MICHAEL ELLIOTT, THE WASHINGTON POST BOOK WORLD"A benchmark for informed speculation on those always fascinating questions: Just where are we in history? What hidden hand is controlling our destiny?...A searching reflection on our global state." --RICHARD BERNSTEIN, THE NEW YORK TIMES"This is what is so stunning about The Clash of Civilizations: It is not just about the future, but may actually help to shape it." --WANG GUNGWU, THE NATIONAL INTEREST

    The remarkable best-seller -- a long-lost, 300-year-old book of wisdom on how to live successfully yet responsibly in a society governed by self-interest -- as acute as Machiavelli yet as humanistic and scrupulously moral as Marcus Aurelius.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.