With rivalries, reversals, and a race against time, the struggle to eradicate polio is one of the great tales of modern history. It begins with the birth of Jonas Salk, shortly before one of the worst polio epidemics in United States history. At the time, the disease was a terrifying enigma: striking from out of nowhere, it afflicted tens of thousands of children in this country each year and left them-literally overnight-paralyzed, and sometimes at death's door. Salk was in medical school just as a president crippled by the disease, Franklin D. Roosevelt, was taking office-and providing the impetus to the drive for studies on polio. By the early 1950s, Salk had already helped create an influenza vaccine, and was hot on the trail of the polio virus. He was nearly thwarted, though, by the politics of medicine and by a rival researcher eager to discredit his proposed solution. Meanwhile, in 1952, polio was spreading in record numbers, with 57,000 cases in the United States that summer alone. In early 1954, Salk was weighing the possibility of trials of a not-yet-perfected vaccine against-as the summer approached-the prospect of thousands more children being struck down by the disease. The results of the history-making trials were announced at a press conference on April 12, 1955: "The vaccine works." The room-and an entire nation-erupted in cheers for this singular medical achievement. Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program-and as humanity is tantalizingly close to eradicating polio worldwide-comes this unforgettable chronicle. Salk's work was an unparalleled achievement-and it makes for a magnificent read.

    As always, Chomsky presents his ideas vividly and accessibly, with uncompromising principle and clarifying insight.The latest volume from a long-established, trusted partnership, Power Systems shows once again that no interlocutor engages with Chomsky more effectively than David Barsamian. These interviews will inspire a new generation of readers, as well as longtime Chomsky fans eager for his latest thinking on the many crises we now confront, both at home and abroad. They confirm that Chomsky is an unparalleled resource for anyone seeking to understand our world today.

    They spread rapidly, even in such seemingly harmless places as high school locker rooms, where they infect young athletes. Throughout the world, many more people are dying from these infections. Astoundingly, as antibiotic resistant infections are skyrocketing in incidence—creating a critical need for new antibiotics—research and development of new antibiotics has ground to a screeching halt!In Rising Plague, Dr. Brad Spellberg—an infectious diseases specialist and member of a national task force charged with attacking antibiotic resistant infections—tells the story of this potentially grave public health crisis. The author shares true and very moving patient stories to emphasize the terrible frustration he and his colleagues have experienced while attempting to treat untreatable infections, not to mention the heart-break and tragedy that many of these patients’ families had to endure. Dr. Spellberg corrects the nearly universal misperception that physician misuse of antibiotics and "dirty hospitals" are responsible for causing antibiotic-resistant infections. He explains the true causes of antibiotic resistance and of the virtual collapse of antibiotic research and development. Most important, he advocates ways to reverse this dire trend and instead bolster the production of desperately needed new and effective antibiotics. He also warns against complacency induced by the decades-old assumption that some miracle drug will always be available to ensure the continuation of our "antibiotic era." If we do nothing, we run the risk of inviting a bleak future when infectious diseases will once again reign supreme. Then many of the medical breakthroughs that we now take for granted—from routine surgery and organ transplants to intensive care and battlefield medicine—might all be threatened.This crucial and timely book is lucidly written in terms that everyone can understand. It issues a call to action, explaining how, through a strong and concerted effort, we can all help prevent this nightmare scenario from happening. By following this courageous doctor’s recommendations, we can assure that magic bullets will be there for our families and us in the future.

    But the town he's sent to is an isolated outpost of mud huts, surrounded by landmines; the hospital, for which he's to be the only doctor, is filled with malnourished children and conditions he's never seen; and the health workers—Angolan war veterans twice his age who speak no English—walk out on him following an altercation on his first shift. In the months that follow, Damien confronts these challenges all the while dealing with the social absurdities of living with only three other volunteers for company. The medical calamities pile up—including a leopard attack, a landmine explosion, and having to perform surgery using tools cleaned on the fire—but it's through Damien's evolving friendships with the local people that his passion for the work grows. This heartbreaking and honest account of life on the medical front line in Angola, Mozambique, and South Sudan is a moving testimony of the work done by medical humanitarian groups and the extraordinary and sometimes eccentric people who work for them.

    And be warned—none of it is pretty.On October 5th, 2017, President Trump made a cryptic extemporaneous remark in the State Dining Room. He called this gathering of top-ranking military officials, "the calm before the storm," and refused to elaborate as journalist and politicos inquired further. But on the infamous message boards of 4chan, elaboration began all on its own.In the days that followed, an anonymous poster spun a yarn inspired by Trump's remarks that rivalled Tom Clancy and satisfied the deepest desires of MAGA-America. Did any of it come to pass? No. Did that stop people from clinging to every word they were reading, expanding its mythology and promoting the theory for years? No.How did this happen, who are these followers, and how do adherents reconcile their worldview with the America they see around them? Mike Rothschild, a journalist specializing in conspiracy theories, explains all--taking readers from the earliest posts on 4Chan to its embrace by right-wing media, and the game that Donald Trump has played with its followers.As rabid adherents to the theory show no sign of calming—with Baby Boomers especially susceptible to its messaging—families are being torn apart and politicians are starting to openly espouse the ideology in their campaigns. It's time to figure out what QAnon is, because QAnon explains everything you need to know about American politics and global fear after Trump.

    During the years when Brazil, India, China and the other “emerging markets” have transformed their economies, Africa's resource states remained tethered to the bottom of the industrial supply chain. While Africa accounts for about 30 per cent of the world's reserves of hydrocarbons and minerals and 14 per cent of the world's population, its share of global manufacturing stood in 2011 exactly where it stood in 2000: at 1 percent.In his first book, The Looting Machine, Tom Burgis exposes the truth about the African development miracle: for the resource states, it's a mirage. The oil, copper, diamonds, gold and coltan deposits attract a global network of traders, bankers, corporate extractors and investors who combine with venal political cabals to loot the states' value. And the vagaries of resource-dependent economies could pitch Africa's new middle class back into destitution just as quickly as they climbed out of it. The ground beneath their feet is as precarious as a Congolese mine shaft; their prosperity could spill away like crude from a busted pipeline.This catastrophic social disintegration is not merely a continuation of Africa's past as a colonial victim. The looting now is accelerating as never before. As global demand for Africa's resources rises, a handful of Africans are becoming legitimately rich but the vast majority, like the continent as a whole, is being fleeced. Outsiders tend to think of Africa as a great drain of philanthropy. But look more closely at the resource industry and the relationship between Africa and the rest of the world looks rather different. In 2010, fuel and mineral exports from Africa were worth 333 billion, more than seven times the value of the aid that went in the opposite direction. But who received the money? For every Frenchwoman who dies in childbirth, 100 die in Niger alone, the former French colony whose uranium fuels France's nuclear reactors. In petro-states like Angola three-quarters of government revenue comes from oil. The government is not funded by the people, and as result it is not beholden to them. A score of African countries whose economies depend on resources are rentier states; their people are largely serfs. The resource curse is not merely some unfortunate economic phenomenon, the product of an intangible force. What is happening in Africa's resource states is systematic looting. Like its victims, its beneficiaries have names.

    Siegel shows how our drinking water got contaminated, what it may be doing to us, and what we must do to make it safe. If you thought America's drinking water problems started and ended in Flint, Michigan, think again. From big cities and suburbs to the rural heartland, chemicals linked to cancer, heart disease, obesity, birth defects, and lowered IQ routinely spill from our taps.Many are to blame: the EPA, Congress, a bipartisan coalition of powerful governors and mayors, chemical companies, and drinking water utilities--even NASA and the Pentagon. Meanwhile, the bottled water industry has been fanning our fears about tap water, but bottled water is often no safer.The tragedy is that existing technologies could launch a new age of clean, healthy, and safe tap water for only a few dollars a week per person.Scrupulously researched, Troubled Water is full of shocking stories about contaminated water found throughout the country and about the everyday heroes who have successfully forced changes in the quality and safety of our drinking water. And it concludes with what America must do to reverse decades of neglect and play-it-safe inaction by government at all levels in order to keep our most precious resource safe.

    After decades of sci-fi fantasies and hype, artificial intelligence has leapt out of research labs and Silicon Valley engineering departments and into the center of our lives. Algorithms shape everything around us, from the news we see to the products we buy and the relationships we form. And while the debate over whether or not automation will destroy jobs rages on, a much more important question is being ignored:What does it mean to be a human in a world that is increasingly built by and for machines?In Futureproof: 9 Rules for Humans in the Age of Automation, New York Times technology columnist Kevin Roose lays out a hopeful, pragmatic vision of how people can succeed in the machine age by making themselves irreplaceably human. He shares the secrets of people and organizations that have survived technological change, and explains how we can protect our own futures, with lessons like- Do work that is surprising, social, and scarce (the types of work machines can't do). - Demote your phone. - Work near other people. - Treat A.I. like an army of chimpanzees. - Add more friction to your life.Roose rejects the conventional wisdom that in order to compete with machines, we have to become more like them--hyper-efficient, data-driven, code-writing workhorses. Instead, he says, we should let machines be machines, and focus on doing the kinds of creative, inspiring, and meaningful things only humans can do.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    Before the invention of photography, artists played an essential role in medical science, recording human anatomy in startlingly direct and often moving images. Over 400 years, beginning with Vesalius, they charted the main systems of the body, made precise studies of living organs, documented embryonic development, and described pathologies. Human Anatomy includes portfolios of the work of 19 great anatomical artists, with concise biographies, and culminates with the Visible Human Project, which uses digital tools to visualize the human body.Praise for Human Anatomy:"From Leonardo da Vinci's exquisite pen-and-ink drawings of the human skeleton to the digital Visible Human Project in its three-dimensional glory, this fascinating book . . . documents more than 500 years of anatomical illustration in living color." -Scientific American

    Yet the term itself did not exist before the emergence of the HIV/AIDS epidemic in the 1980s. How did this idea so swiftly come to exert such a strong grip on the scientific, media, and popular consciousness? In Patient Zero, Richard A. McKay interprets a wealth of archival sources and interviews to demonstrate how this seemingly new concept drew upon centuries-old ideas—and fears—about contagion and social disorder. McKay presents a carefully documented and sensitively written account of the life of Gaétan Dugas, a gay man whose skin cancer diagnosis in 1980 took on very different meanings as the HIV/AIDS epidemic developed—and who received widespread posthumous infamy when he was incorrectly identified as patient zero of the North American outbreak. McKay shows how investigators from the US Centers for Disease Control inadvertently created the term amid their early research into the emerging health crisis; how an ambitious journalist dramatically amplified the idea in his determination to reframe national debates about AIDS; and how many individuals grappled with the notion of patient zero—adopting, challenging and redirecting its powerful meanings—as they tried to make sense of and respond to the first fifteen years of an unfolding epidemic. With important insights for our interconnected age, Patient Zero untangles the complex process by which individuals and groups create meaning and allocate blame when faced with new disease threats. What McKay gives us here is myth-smashing revisionist history at its best.

    The book shines much-needed light on this group of small nations, largely unnoticed by the industrialized West, that are dropping further and further behind the majority of the world's people, often falling into an absolute decline in living standards. A struggle rages within each of these nations between reformers and corrupt leaders--and the corrupt are winning. Collier analyzes the causes of failure, pointing to a set of traps that ensnare these countries, including civil war, a dependence on the extraction and export of natural resources, and bad governance. Standard solutions do not work, he writes; aid is often ineffective, and globalization can actually make matters worse, driving development to more stable nations. What the bottom billion need, Collier argues, is a bold new plan supported by the Group of Eight industrialized nations. If failed states are ever to be helped, the G8 will have to adopt preferential trade policies, new laws against corruption, new international charters, and even conduct carefully calibrated military interventions. Collier has spent a lifetime working to end global poverty. In The Bottom Billion, he offers real hope for solving one of the great humanitarian crises facing the world today.

    Neither Jefferson nor the other Found­ers could ever have envisioned the modern national security state, with its tens of thousands of "privateers"; its bloated Department of Homeland Security; its rust­ing nuclear weapons, ill-maintained and difficult to dismantle; and its strange fascination with an unproven counterinsurgency doctrine. Written with bracing wit and intelligence, Rachel Maddow's Drift argues that we've drifted away from America's original ideals and become a nation weirdly at peace with perpetual war, with all the financial and human costs that entails. To understand how we've arrived at such a dangerous place, Maddow takes us from the Vietnam War to today's war in Afghanistan, along the way exploring the disturbing rise of executive authority, the gradual outsourcing of our war-making capabilities to private companies, the plummeting percentage of American families whose children fight our constant wars for us, and even the changing fortunes of G.I. Joe. She offers up a fresh, unsparing appraisal of Reagan's radical presidency. Ultimately, she shows us just how much we stand to lose by allowing the priorities of the national security state to overpower our political discourse. Sensible yet provocative, dead serious yet seri­ously funny, Drift will reinvigorate a "loud and jangly" political debate about how, when, and where to apply America's strength and power--and who gets to make those decisions.From the Hardcover edition.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    A large and growing chunk of the American population was so turned off--or radicalized--by electoral chicanery, a spineless news media, and the increasingly blatant lies from our leaders ("they hate us for our freedom") that they abandoned the political mainstream altogether. They joined what he calls The Great Derangement.Taibbi tells the story of this new American madness by inserting himself into four defining American subcultures: • The Military, where he finds himself mired in the grotesque black comedy of the American occupation of Iraq;• The System, where he follows the money-slicked path of legislation in Congress;• The Resistance, where he doubles as chief public antagonist and undercover member of the passionately bonkers 9/11 Truth Movement; and• The Church, where he infiltrates a politically influential apocalyptic mega-ministry in Texas and enters the lives of its desperate congregants. Together these four interwoven adventures paint a portrait of a nation dangerously out of touch with reality and desperately searching for answers in all the wrong places. Funny, smart, and a little bit heartbreaking, The Great Derangement is an audaciously reported, sobering, and illuminating portrait of America at the end of the Bush era."The funniest angry writer and the angriest funny writer since Hunter S. Thompson roared into town." -- James Wolcott"…[A] scabrous, hilarious vivisection of our disintegrating nation. …Taibbi shines a light on the corruption, absurdities, and idiot pieties of modern American politics. Beneath his cynical fury, though, are flashes of surprising compassion for the adrift credulous souls who are taken in by it all." -- Michelle Goldberg