For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    This is Nick's story of his world record-breaking adventure and the extraordinary people who joined him along the way. On January 6th 2018, Nick Butter tied his laces and stepped out on to an icy pavement in Toronto, where he began to take the first steps of an epic journey that would see him run 196 marathons in every one of the world's 196 countries. Spending almost two years on the road and relying on the kindness of strangers to keep him moving, Nick's odyssey allowed him to travel slowly, on foot, immersing himself in the diverse cultures and customs of his host nations. Running through capital cities and deserts, around islands and through spectacular landscapes, Nick dodges bullets in Guinea-Bissau, crosses battlefields in Syria, survives a wild dog attack in Tunisia and runs around an erupting volcano in Guatemala. Along the way, he is often joined by local supporters and fellow runners, curious children and bemused passers-by. Telling their stories alongside his own, Nick captures the unique spirit of each place he visits and forges a new relationship with the world around him. Running the World captures Nick's journey as he sets three world records and covers over five thousand miles. As he recounts his adventures, he shares his unique perspective on our glorious planet, celebrates the diversity of human experience, and reflects on the overwhelming power of running.

    Provies basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

    Catch a glimpse of what she saw, touched, smelled, and even tasted during an average workday. Dare to join her as she takes you through a difficult journey of memories, uncovering layers of emotional trauma left behind. Discover the ways she healed from yesterday's pain to live an emotionally balanced life today.

    •Practice exercises are given at the end of chapter included conceptual questions & multiple choice questions with hints, answer & solutions. •Multiple choice questions with single correct and more the one correct answers, Comprehension based questions, Assertion-Reason, Matching Type questions, etc. •Objective answers are provided at the end of every chapter. •Solutions & Explanations are given at the end of every chapter for clear the concepts. •More than 3000 Subjective/Numerical practice exercise with incisive solutions.

    The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex concepts more easily. In addition to the book, you will also receive STUDENT CONSULT, enabling you to access the complete contents of the book online, anywhere you go

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    To top it he had speech difficulties and was vague and inattentive. Albert hated the kind of rote learning he was obliged to do in school, memorizing dates and texts. But as he grew older, it became clear that Albert was no ordinary person. 1905 is often termed his 'miracle year', the year he published not one but four entirely new papers, on four completely different topics.

    VIDEO TRAINING. 12+ HOURS of searchable video training (requires Internet access). If you learn better from videos, watch the videos and use the ebook only for quick reference. If you learn better from books, read the ebook and refer to the videos to see the author demonstrate real world editing techniques. This much video training usually costs over $100 or requires a monthly subscription. 2. 150+ PRESETS. Jump-start your creativity by using the included presets to give your pictures a unique look. Others charge over $200 for this many presets! 3. 50+ RAW PICTURE FILES. Work alongside many of the book's examples, or just learn by experimenting with professional photos. 4. TEACHER & PEER SUPPORT. After buying the book, you get access to the private group on Facebook where you can ask the questions and post pictures for feedback from Tony, Chelsea, and other readers. It’s like being able to raise your hand in class and ask a question! Instructions are in the introduction. With this video book, you ll learn how to instantly find any picture in your library, fix common photography problems, clean up your images, add pop to boring pictures, retouch portraits, make gorgeous prints, create photo books, and even edit your home videos. Tony goes beyond teaching you how to use Lightroom. Tony shows you why and when to use each feature to create stunning, natural photos. When Lightroom is not the best tool, Tony suggests better alternatives. Tony covers every aspect of Lightroom in-depth, but structures his teaching so that both beginner and advanced photographers can learn as efficiently as possible. If you just want a quick start, you can watch the first video or read the first chapter and you'll be organizing and editing your pictures in less than an hour. If you want to know more about a specific feature, switch to that video or jump to that chapter in the ebook. If you want to know everything about Lightroom, watch the videos and read the book from start to finish.

    Whether you are a patient struggling with miscarriages or a medical provider caring for patients with recurrent pregnancy loss, you will learn something from this resource. Dr. Shahine explains not only a typical Western medicine approach to evaluation and treatment for miscarriage but also includes Eastern approaches to care, lifestyle factors that will decrease your risk of miscarriage, and the emotional impact of recurrent pregnancy loss. You will finish this book feeling more empowered to be an advocate for your care and more hopeful than ever to continue towards your family goals. “I have one word to describe this fabulous book: FINALLY. Women with recurrent pregnancy loss have been needing this book for years.” – Dr. Alice Domar, associate professor of obstetrics, gynecology, and reproductive biology at Harvard Medical School and author of Conquering Infertility and Finding Calm for the Expectant Mom

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    News of both the Ice Man's discovery and his age, which was put at over five thousand years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative of a man who died thousands of years ago?In The Seven Daughters of Eve, he gives us a firsthand account of his research into a remarkable gene, which passes undiluted from generation to generation through the maternal line. After plotting thousands of DNA sequences from all over the world, Sykes found that they clustered around a handful of distinct groups. Among Europeans and North American Caucasians, there are, in fact, only seven. This conclusion was staggering: almost everyone of native European descent, wherever they may live throughout the world, can trace their ancestry back to one of seven women, the Seven Daughters of Eve.Naming them Ursula, Xenia, Helena, Velda, Tara, Katrine, and Jasmine, Sykes has created portraits of their disparate worlds by mapping the migratory patterns followed by millions of their ancestors. In reading the stories of these seven women, we learn exactly how our origins can be traced, how and where our ancient genetic ancestors lived, and how we are each living proof of the almost indestructible strands of DNA, which have survived over so many thousands of years. Indeed, The Seven Daughters of Eve is filled with dramatic stories: from Sykes's identification, using DNA samples from two living relatives, of the remains of Tsar Nicholas and Tsaress Alexandra, to the Caribbean woman whose family had been sold into slavery centuries before and whose ancestry Sykes was able to trace back to the Eastern coast of central Africa. Ultimately, Sykes's investigation reveals that, as a race, what humans have in common is more deeply embedded than what separates us.

    

    But Max Leonard, himself an accomplished amateur cyclist, does not forget the pain, the glory, the sweat, and the tears that go into these grueling climbs.  After all, cycling up a mountain is hard.  So hard that, to many, it can seem absurd. But for others, climbing a mountain gracefully (and beating your competitors up the slope) represents the pinnacle of cycling achievement. It is where legends are forged.Many books tell you where the mountains are, or how long and how high. None of them ask why. Why are mountain ranges professional cycling’s Coliseum? Why do amateurs also make pilgrimages to these high, remote roads? Why are the roads even there in the first place to lure us on to these obsession inducing climbs?   Just why are mountains so enthralling? “This is real cycling, where the glory is and where dreams come true,” according to Bradley Wiggins. Mountains are where cycling's greatest heroes have made their names. Every amateur rider wishes they could climb better, too.  Are all these people addicted to the pain? To the achievement? Or to the allure of the peaks? Some spend their weekends and holidays cycling up mountains from start to finish. But how does a rider push themselves beyond their limits to get up a 10% gradient on pedal power alone? What is happening when they do?A Higher Calling explores the central place of mountains in the folklore of road cycling. Blending adventure and travel writing with the rich narrative of racing, Max Leonard takes the reader from the battles that created the Alpine roads to the shepherds tending their flocks on the peaks, and to a Grand Tour climax on the “highest road in Europe.” And he tells stories of courage and sacrifice, war and love, obsession and even elephants, along the way.