Together these twenty-one articles on a wide range of today's most leading topics in science, from Dennis Overbye, Jonathan Weiner, and Richard Preston, among others, represent the full spectrum of scientific inquiry, proving once again that "good science writing is evidently plentiful" (American Scientist).

    Within a few short decades the most hostile of the world’s environments had all been conquered. Likewise, in the twentieth century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremis, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer. Doctors, scientists, and explorers all share a defining trait: they push on in the face of grim odds. Because of their extreme exploration we not only understand our physiology better; we have also made enormous strides in the science of healing.Drawing on his own experience as an anesthesiologist, intensive care expert, and NASA adviser, Dr. Kevin Fong examines how cuttingedge medicine pushes the envelope of human survival by studying the human body’s response when tested by physical extremes. Extreme Medicine explores different limits of endurance and the lens each offers on one of the systems of the body. The challenges of Arctic exploration created opportunities for breakthroughs in open heart surgery; battlefield doctors pioneered techniques for skin grafts, heart surgery, and trauma care; underwater and outer space exploration have revolutionized our understanding of breathing, gravity, and much more. Avant-garde medicine is fundamentally changing our ideas about the nature of life and death.Through astonishing accounts of extraordinary events and pioneering medicine, Fong illustrates the sheer audacity of medical practice at extreme limits, where human life is balanced on a knife’s edge. Extreme Medicine is a gripping debut about the science of healing, but also about exploration in its broadest sense—and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.

    The discovery initiated Gessen into a club of sorts: the small (but exponentially expanding) group of people in possession of a new and different way of knowing themselves through what is inscribed in the strands of their DNA. As she wrestled with a wrenching personal decision—what to do with such knowledge—Gessen explored the landscape of this brave new world, speaking with others like her and with experts including medical researchers, historians, and religious thinkers. Blood Matters is a much-needed field guide to this unfamiliar and unsettling territory. It explores the way genetic information is shaping the decisions we make, not only about our physical and emotional health but about whom we marry, the children we bear, even the personality traits we long to have. And it helps us come to terms with the radical transformation that genetic information is engineering in our most basic sense of who we are and what we might become.

    She loved the ocean and wrote three books about its mysteries, including the international bestseller The Sea Around Us. But it was with her fourth book, Silent Spring, that this unassuming biologist transformed our relationship with the natural world.Rachel Carson began work on Silent Spring in the late 1950s, when a dizzying array of synthetic pesticides had come into use. Leading this chemical onslaught was the insecticide DDT, whose inventor had won a Nobel Prize for its discovery. Effective against crop pests as well as insects that transmitted human diseases such as typhus and malaria, DDT had at first appeared safe. But as its use expanded, alarming reports surfaced of collateral damage to fish, birds, and other wildlife. Silent Spring was a chilling indictment of DDT and its effects, which were lasting, widespread, and lethal.Published in 1962, Silent Spring shocked the public and forced the government to take action-despite a withering attack on Carson from the chemicals industry. The book awakened the world to the heedless contamination of the environment and eventually led to the establishment of the EPA and to the banning of DDT and a host of related pesticides. By drawing frightening parallels between dangerous chemicals and the then-pervasive fallout from nuclear testing, Carson opened a fault line between the gentle ideal of conservation and the more urgent new concept of environmentalism.Elegantly written and meticulously researched, On a Farther Shore reveals a shy yet passionate woman more at home in the natural world than in the literary one that embraced her. William Souder also writes sensitively of Carson's romantic friendship with Dorothy Freeman, and of her death from cancer in 1964. This extraordinary new biography captures the essence of one of the great reformers of the twentieth century.A New York Times Notable Book of 2012“A suspenseful tale of the literary life…utterly inspiring.” —San Francisco Chronicle“Captivating…Souder writes vividly and with great empathy for his subject and her cause.” —New York Times Book Review“A delightful, fascinating, engrossing read about some of the most important insights of modern science. You’ll find yourself thinking about Carson whenever you take a walk in the woods.” —Slate.com

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    Genes are important, but only as part of a process constrained by environment, physical laws, and the universal tendencies of complex adaptive systems. In a new preface for this edition, Goodwin reflects on the advances in both genetics and the sciences of complexity since the book's original publication.

    Juan Enriquez puts you face to face with unprecedented political, ethical, economic, and financial issues, dramatically demonstrating the cascading impact of the genetic, digital, and knowledge revolutions on all our lives. Genetics will be the dominant language of this century. Those who can “speak it” will acquire direct and deliberate control over all forms of life. But most countries and individuals remain illiterate in what is rapidly becoming the greatest single driver of the global economy. The choice is simple: Either learn to surf new and powerful waves of change—or get crushed trying to stop them. The future is catching us all. Let it catch you with your eyes wide open.

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    We find animals and plants where we do because, over time, the continents have moved, separating and uniting in a long, slow dance; because sea levels have risen, cutting off one bit of land from another; because new and barren volcanic islands have risen up from the sea; and because animals and plants vary greatly in their ability to travel, and separation causes the formation of new species. This is the story of how life has responded to, and has in turn altered, the ever-changing Earth. And it includes many fascinating tales--of pygmy mammoths and elephant birds and of radical ideas by bold young scientists.

    With personal anecdotes, a well-written narrative, and clear examples, Human Natures is a major work of synthesis and scholarship as well as a valuable primer on genetics and evolution that makes complex scientific concepts accessible to lay readers.

    Whereas his theory of natural selection dictates that species adapt the most efficient and logical traits (a streamlined fin, say, or a long wingspan), Generous Man makes the case that an animal's success, sexually, depends on developing the least efficient traits. Nørretranders uses as the central symbol of his theory the peacock's plumage. It's cumbersome, showy, and inefficient — and therefore terribly attractive to peahens. Put more simply, nothing shows a potential mate just how worthy you are as a partner than your ability to be wasteful and inefficient. It's like a man with money to burn. But money isn't everything: humans really measure their worth by doing something that's difficult. This is a central — though hitherto overlooked — factor in evolution. In order to win a partner to mate with, humans display their best sides. We strive for perfection, prove we are willing to help others, show consideration, and go out of our way. In other words, we are generous. This book shows how our nobler traits derive from our need for sex and are, in fact, the best way to get more of it.

    During World War I, the young women who were hired to work in America's radium watch dial factories were considered the lucky ones. They were paid well, they got to work with the luminous element dubbed "liquid sunshine" that was all the rage, and they were helping the war effort by providing instruments that shone in the dark. And their bodies literally glowed because of the amount of radium they were ingesting. In her new book, The Radium Girls: The Dark Story of America's Shining Women, author Kate Moore gives voice to two groups of workers who became horribly ill and fought back against the companies that poisoned them. Using diaries and letters from the women, their statements in court documents, medical records and archived x-rays, as well as using ancestry documents to track down their relatives for interviews, Moore showcases the forgotten young women whose legal fight led to life-changing workplace safety regulations amid one of the biggest scandals of America's twentieth century. Preorder and find out how their story ends on May 2.

    The adjective 'medieval' has become a synonym for brutality and uncivilized behavior. Yet without the work of medieval scholars there could have been no Galileo, no Newton and no Scientific Revolution. In God's Philosophers, James Hannam debunks many of the myths about the Middle Ages, showing that medieval people did not think the earth is flat, nor did Columbus 'prove' that it is a sphere; the Inquisition burnt nobody for their science nor was Copernicus afraid of persecution; no Pope tried to ban human dissection or the number zero. God's Philosophers is a celebration of the forgotten scientific achievements of the Middle Ages - advances which were often made thanks to, rather than in spite of, the influence of Christianity and Islam. Decisive progress was also made in technology: spectacles and the mechanical clock, for instance, were both invented in thirteenth-century Europe. Charting an epic journey through six centuries of history, God's Philosophers brings back to light the discoveries of neglected geniuses like John Buridan, Nicole Oresme and Thomas Bradwardine, as well as putting into context the contributions of more familiar figures like Roger Bacon, William of Ockham and Saint Thomas Aquinas.

    As a sympathetic brain detective, Klawans deduced a great deal from his patients, not only about the immediate causes of their ailments but also about the evolutionary underpinnings of their behaviour.