Book picks similar to
DNA: The Story of the Genetic Revolution by James D. Watson
science
non-fiction
biology
genetics
Human Errors: A Panorama of Our Glitches, from Pointless Bones to Broken Genes
Nathan H. Lents - 2018
But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them. A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.
The Violinist's Thumb: And Other Lost Tales of Love, War, and Genius, as Written by Our Genetic Code
Sam Kean - 2012
In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.
Life's Greatest Secret: The Race to Crack the Genetic Code
Matthew Cobb - 2015
Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.
Life on the Edge: The Coming of Age of Quantum Biology
Johnjoe McFadden - 2014
Life remains the only way to make life. Are we still missing a vital ingredient in its creation? Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness
Peter Godfrey-Smith - 2016
In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.
Skeleton Keys: The Secret Life of Bone
Brian Switek - 2019
It gives your body its shape and the ability to move. It grows and changes with you, an undeniable document of who you are and how you lived. Arguably, no other part of the human anatomy has such rich scientific and cultural significance, both brimming with life and a potent symbol of death.In this delightful natural and cultural history of bone, Brian Switek explains where our skeletons came from, what they do inside us, and what others can learn about us when these artifacts of mineral and protein are all we've left behind.Bone is as embedded in our culture as it is in our bodies. Our species has made instruments and jewelry from bone, treated the dead like collectors' items, put our faith in skull bumps as guides to human behavior, and arranged skeletons into macabre tributes to the afterlife. Switek makes a compelling case for getting better acquainted with our skeletons, in all their surprising roles. Bridging the worlds of paleontology, anthropology, medicine, and forensics, Skeleton Keys illuminates the complex life of bones inside our bodies and out.
The Rules of Contagion: Why Things Spread - and Why They Stop
Adam Kucharski - 2020
But how does virality actually work? In The Rules of Contagion, epidemiologist Adam Kucharski explores topics including gun violence, online manipulation, and, of course, outbreaks of disease to show how much we get wrong about contagion, and how astonishing the real science is.Why did the president retweet a Mussolini quote as his own? Why do financial bubbles take off so quickly? And why are disinformation campaigns so effective? By uncovering the crucial factors driving outbreaks, we can see how things really spread -- and what we can do about it.Whether you are an author seeking an audience, a defender of truth, or simply someone interested in human social behavior, The Rules of Contagion is an essential guide to modern life.
The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution
Sean B. Carroll - 2006
Over the last two decades, it has emerged as a powerful tool for solving crimes and determining guilt and innocence. But, very recently, an important new aspect of DNA has been revealed—it contains a detailed record of evolution. That is, DNA is a living chronicle of how the marvelous creatures that inhabit our planet have adapted to its many environments, from the freezing waters of the Antarctic to the lush canopy of the rain forest.In the pages of this highly readable narrative, Sean Carroll guides the general reader on a tour of the massive DNA record of three billion years of evolution to see how the fittest are made. And what a eye-opening tour it is—one featuring immortal genes, fossil genes, and genes that bear the scars of past battles with horrible diseases. This book clinches the case for evolution, beyond any reasonable doubt.
The Pandemic Century: One Hundred Years of Panic, Hysteria, and Hubris
Mark Honigsbaum - 2019
Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.
Why Evolution Is True
Jerry A. Coyne - 2008
In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.
Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life
Eva Jablonka - 2005
New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.
Full House: The Spread of Excellence from Plato to Darwin
Stephen Jay Gould - 1996
Although valuable, the risk is that we ignore variations and end up with a skewed view of reality. In evolutionary terms, the result is a view in which humans are the inevitable pinnacle of evolutionary progress, instead of, as Stephen Jay Gould patiently argues, "a cosmic accident that would never arise again if the tree of life could be replanted." The implications of Gould's argument may threaten certain of our philosophical and religious foundations but will in the end provide us with a clearer view of, and a greater appreciation for, the complexities of our world.
To Explain the World: The Discovery of Modern Science
Steven Weinberg - 2015
He shows that the scientists of ancient and medieval times not only did not understand what we understand about the world—they did not understand what there is to understand, or how to understand it. Yet over the centuries, through the struggle to solve such mysteries as the curious backward movement of the planets and the rise and fall of the tides, the modern discipline of science eventually emerged. Along the way, Weinberg examines historic clashes and collaborations between science and the competing spheres of religion, technology, poetry, mathematics, and philosophy.An illuminating exploration of the way we consider and analyze the world around us, To Explain the World is a sweeping, ambitious account of how difficult it was to discover the goals and methods of modern science, and the impact of this discovery on human knowledge and development.
Rare Earth: Why Complex Life Is Uncommon in the Universe
Peter D. Ward - 2000
In doing so, the authors synthesize information from astronomy, biology, and paleontology, and apply it to what we know about the rise of life on Earth and to what could possibly happen elsewhere in the universe. Everyone who has been thrilled by the recent discoveries of extrasolar planets and the indications of life on Mars and the Jovian moon Europa will be fascinated by Rare Earth, and its implications for those who look to the heavens for companionship.
Freaks of Nature: What Anomalies Tell Us about Development and Evolution
Mark S. Blumberg - 2008
Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.