Whether it's something as minor as a brush with the common cold or as serious as Ebola, we all have grappled with infections and will continue to encounter them as we age.On a worldwide scale, infectious diseases account for 26 percent of all deaths, second only to cardiovascular diseases. And unlike chronic diseases, infectious diseases are unique in their potential for explosive global impacts.Now, in the 24 engaging lectures of Introduction to Infectious Diseases, you can get a comprehensive overview of diseases from the mundane to the fatal from renowned physician and award-winning professor Dr. Barry Fox.Begin with an overview of the microscopic particles responsible for disease: bacteria, fungi, hybrid germs, and viruses. You will see how they invade the body; look through the microscope at pathogens to identify their inner components; follow germs through to different body systems and see what effects they have; and learn why we may be losing the battle against some germs.

    David Christian, professor of history at San Diego State University, surveys the past at all possible scales, from conventional history, to the much larger scales of biology and geology, to the universal scales of cosmology.

    This is a world tour of prehistory with profound links to who we are and how we live today.2.5 Million Years of HistoryThis 36-lecture narrative covers human prehistory from our beginnings more than 2.5 million years ago up to and beyond the advent of the world's first preindustrial civilizations.Due to the large spans of time and geography covered in this series, these lectures are divided into six sections:Section I: BeginningsThis section surveys the archaic world of the first humans, you travel into the remote past, learning why the late Harvard biologist Stephen Jay Gould was probably right to observe that we all come from the same African twig on the bushy tree of human evolution.You examine prehistory from Australopithecus africanus through Homo habilis (the first tool-making hominid), and Homo erectus (whose remains were first found on Java but whose origins lie in Africa) through the hardy Neanderthals who lived and hunted successfully in Europe despite the bitter grip of the last Ice Age 100,000 and more years ago. You focus on the first human settlement of Africa as early as 800,000 years ago.Section II: Modern HumansThis section tells the story of the great diaspora of anatomically modern humans in the late Ice Age. Whether and how these modern humans spread from the African tropics into southwestern Asia and beyond remains one of the great controversies among scholars of prehistory.You follow Homo sapiens sapiens north into Europe some 45,000 years ago. You meet the Cro-Magnons, among the first known artists as well as hunter-gatherers, who exhibited degrees of spiritual awareness, social interaction, and fluid intelligence.You venture into the frigid open plains of the Ukraine and Eurasia, where big-game hunters flourished in spite of nine-month winters. Moving to the Americas, debate over the origins of the first human settlement continues.Section III: Farmers and HerdersThis section describes perhaps the most important development in all human prehistory: the beginnings of agriculture and animal domestication.This defining chapter began about 12,000 years ago, when hunter-gatherers in the Near East broke from the long human tradition of intensely mobile foraging and turned to more settled ways of life built around cultivating cereal grains or tending animals.Section IV: Eastern Mediterranean CivilizationsProfessor Fagan describes early civilizations in an increasingly complex eastern Mediterranean world, discussing many theories accounting for the appearance of urban civilization and overall attributes of preindustrial civilizations.You examine Sumerian civilization in Mesopotamia and the intricate patchwork of city-states between the Tigris and Euphrates Rivers. You explore ancient Egypt, the Minoan civilization of Crete, the Mycenaeans, and the Hittites.You learn about the Uluburun shipwreck of southern Turkey, a sealed capsule of international trade from 3,000 years ago.Section V: Africans and AsiansYou analyze the beginnings of South Asian civilization and the mysterious Harappan civilization of the Indus, which traded with Mesopotamia. Professor Fagan resumes the story of South Asian civilization after the collapse of the Harappan and shows how Mauryan rulers on the Ganges encouraged trading much farther afield.You see the impact of monsoons which revolutionized maritime trading among Africa, India, and Southeast Asia, and explore Meroe, Aksum, and the coastal civilization of East Africa.Several lectures cover the beginnings of civilization in China and Southeast Asia.Section VI: Ancient AmericansProfessor Fagan takes you into sophisticated chiefdoms and civilizations that developed in the Americas over the past 3,500 years, including Pueblo cultures of the North American Southwest and the Mississippian culture of the South and Southeast. You learn about Mesoamerican civilization, primordial Olmec culture of the lowlands, and the spectacular ancient Maya civilization.Moving to the highlands, you visit the city-states of Monte Albán in the Valley of Oaxaca and Teotihuacán near the Valley of Mexico. Professor Fagan also describes the rise of Aztec civilization, followed by a journey to the Andes. Finally, you explore the southern highlands, with the rise of Tiwanaku near Lake Titicaca, the Chimu civilization of the coast, and the huge Inka empire.The series closes by analyzing the closing centuries of prehistoric times during the European age of discovery and summarizing the main issues and themes of the course: * What was involved in the archaic world * The appearance and spread of modern humans * Food production * The development of states.

    And it has an undeniable power to move us in ways that enrich our lives - provided it is understood.If you have ever longed to appreciate great concert music, to learn its glorious language and share in its sublime pleasures, the way is now open to you, through this series of 48 wonderful lectures designed to make music accessible to everyone who yearns to know it, regardless of prior training or knowledge. It's a lecture series that will enable you to first grasp music's forms, techniques, and terms - the grammatical elements that make you fluent in its language - and then use that newfound fluency to finally hear and understand what the greatest composers in history are actually saying to us.And as you learn the gifts given us by nearly every major composer, you'll come to know there is one we share with each of them - a common humanity that lets us finally understand that these were simply people speaking to us, sharing their passion and wanting desperately to be heard. Using digitally recorded musical passages to illustrate his points, Professor Greenberg will take you inside magnificent compositions by Bach, Handel, Haydn, Mozart, Beethoven, Chopin, Verdi, Wagner, Brahms, Tchaikovsky, Stravinsky, and more. Even if you have listened to many of these illustrative pieces throughout your life - as so many of us have - you will never hear them the same way again after experiencing these lectures.

    But to those who collect them, the map trade can be a cutthroat business, inhabited by quirky and sometimes disreputable characters in search of a finite number of extremely rare objects. Once considered a respectable antiquarian map dealer, E. Forbes Smiley spent years doubling as a map thief —until he was finally arrested slipping maps out of books in the Yale University library. The Map Thief delves into the untold history of this fascinating high-stakes criminal and the inside story of the industry that consumed him. Acclaimed reporter Michael Blanding has interviewed all the key players in this stranger-than-fiction story, and shares the fascinating histories of maps that charted the New World, and how they went from being practical instruments to quirky heirlooms to highly coveted objects. Though pieces of the map theft story have been written before, Blanding is the first reporter to explore the story in full—and had the rare privilege of having access to Smiley himself after he’d gone silent in the wake of his crimes. Moreover, although Smiley swears he has admitted to all of the maps he stole, libraries claim he stole hundreds more—and offer intriguing clues to prove it. Now, through a series of exclusive interviews with Smiley and other key individuals, Blanding teases out an astonishing tale of destruction and redemption. The Map Thief interweaves Smiley’s escapades with the stories of the explorers and mapmakers he knew better than anyone. Tracking a series of thefts as brazen as the art heists in Provenance and a subculture as obsessive as the oenophiles in The Billionaire’s Vinegar, Blanding has pieced together an unforgettable story of high-stakes crime.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    From body lotion to tonic water, the popular new element shines bright in the otherwise dark years of the First World War.Meanwhile, hundreds of girls toil amidst the glowing dust of the radium-dial factories. The glittering chemical covers their bodies from head to toe; they light up the night like industrious fireflies. With such a coveted job, these "shining girls" are the luckiest alive—until they begin to fall mysteriously ill.But the factories that once offered golden opportunities are now ignoring all claims of the gruesome side effects, and the women's cries of corruption. And as the fatal poison of the radium takes hold, the brave shining girls find themselves embroiled in one of the biggest scandals of America's early 20th century, and in a groundbreaking battle for workers' rights that will echo for centuries to come.Written with a sparkling voice and breakneck pace, The Radium Girls fully illuminates the inspiring young women exposed to the "wonder" substance of radium, and their awe-inspiring strength in the face of almost impossible circumstances. Their courage and tenacity led to life-changing regulations, research into nuclear bombing, and ultimately saved hundreds of thousands of lives.

    Two years later, Clea Koff, a twenty-three-year-old forensic anthropologist, left the safe confines of a lab in Berkeley, California, to serve as one of sixteen scientists chosen by the United Nations to unearth the physical evidence of the Rwandan genocide. Over the next four years, Koff’s grueling investigations took her across geography synonymous with some of the worst crimes of the twentieth century. The Bone Woman is Koff’s unflinching, riveting account of her seven UN missions to Bosnia, Croatia, Kosovo, and Rwanda, as she shares what she saw, how it affected her, who was prosecuted based on evidence she found, and what she learned about the world. Yet even as she recounts the hellish nature of her work and the heartbreak of the survivors, she imbues her story with purpose, humanity, and a sense of justice. A tale of science in service of human rights, The Bone Woman is, even more profoundly, a story of hope and enduring moral principles.

    And a very strange, very English obsession. But where did this fixation develop? And what does it tell us about ourselves?In The Art of the English Murder, Lucy Worsley explores this phenomenon in forensic detail, revisiting notorious crimes like the Ratcliff Highway Murders, which caused a nationwide panic in the early nineteenth century, and the case of Frederick and Maria Manning, the suburban couple who were hanged after killing Maria's lover and burying him under their kitchen floor. Our fascination with crimes like these became a form of national entertainment, inspiring novels and plays, prose and paintings, poetry and true-crime journalism. At a point during the birth of modern England, murder entered our national psyche, and it's been a part of us ever since.The Art of the English Murder is a unique exploration of the art of crime and a riveting investigation into the English criminal soul by one of our finest historians.

    In this course brought to you in partnership with HISTORY, you will be visiting some of history’s deepest rabbit-holes, across centuries and continents, in search of secret societies in all their varieties. You will journey to some very dark places, and frankly some odd and sometimes silly ones as well. During 24 eye-opening lectures, Dr. Richard B. “Rick” Spence, Professor of History at the University of Idaho, guides you through the fascinating, often mystifying - sometimes disturbing - world of brotherhoods, sisterhoods, orders, cults, and cabals that have influenced human culture from ancient times to the present.You’ll understand how and why secret societies have attracted some of history’s most brilliant, and some of its most evil, minds. Often demonized by their enemies, many secret societies have become the stuff of myths and conspiracy theories. Why do they exist? And when they are invented or imagined, why would someone pretend they exist? What do secret societies believe? Who do they recruit? Most important, what influence do they have? Buckle up and get ready to find out.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Now the man who coined the phrase "serial killer" and advised Thomas Harris on The Silence of the Lambs shows how is able to track down some of today's most brutal murderers.Just as it happened in The Silence of the Lambs, Ressler used the evidence at a crime scene to put together a psychological profile of the killers. From the victims they choose, to the way they kill, to the often grotesque souvenirs they take with them--Ressler unlocks the identities of these vicious killers of the police to capture.And with his discovery that serial killers share certain violent behaviors, Ressler's gone behind prison walls to hear the bizarre first-hand stories countless convicted murderers. Getting inside the mind of a killer to understand how and why he kills, is one of the FBI's most effective ways of helping police bring in killers who are still at large.Join Ressler as he takes you on the hunt for toady's most dangerous psychopaths. It is a terrifying journey you will not forget.

    The story has been the subject of websites, short stories, novels, a graphic novel, and most recently the FX television series American Horror Story. But the full story of gruesome murders, sympathetic victims, accused innocents, public panic, the New Orleans Mafia, and a mysterious killer has never been written. Until now.  The Axeman repeatedly broke into the homes of Italian grocers in the dead of night, leaving his victims in a pool of blood. Iorlando Jordano, an innocent Italian grocer, and his teenaged son Frank were wrongly accused of one of those murders; corrupt officials convicted them with coerced testimony. Miriam C. Davis here expertly tells the story of the search for the Axeman and of the eventual exoneration of the innocent Jordanos. She proves that the person mostly widely suspected of being the Axeman was not the killer. She also shows what few have suspected—that the Axeman continued killing after leaving New Orleans in 1919. Only thirty years after Jack the Ripper stalked the streets of Whitechapel, the Axeman of New Orleans held an American city hostage. This book tells that story.

    The Great Ideas of Classical Physics 2. Describing MotionA Break from Aristotle 3. Describing Ever More Complex Motion 4. Astronomy as a Bridge to Modern Physics 5. Isaac NewtonThe Dawn of Classical Physics 6. Newton QuantifiedForce and Acceleration 7. Newton and the Connections to Astronomy 8. Universal Gravitation 9. Newton's Third Law 10. Conservation of Momentum 11. Beyond NewtonWork and Energy 12. Power and the Newtonian Synthesis 13. Further DevelopmentsStatic Electricity 14. Electricity, Magnetism, and Force Fields 15. Electrical Currents and Voltage 16. The Origin of Electric and Magnetic Fields 17. Unification IMaxwell's Equations 18. Unification IIElectromagnetism and Light 19. Vibrations and Waves 20. Sound Waves and Light Waves 21. The Atomic Hypothesis 22. Energy in SystemsHeat and Thermodynamics 23. Heat and the Second Law of Thermodynamics 24. The Grand Picture of Classical Physics

    But one perspective has been missing up to this point—a 360-degree account of the day told through firsthand.Now, in The Only Plane in the Sky, Garrett Graff tells the story of the day as it was lived—in the words of those who lived it. Drawing on never-before-published transcripts, declassified documents, original interviews, and oral histories from nearly five hundred government officials, first responders, witnesses, survivors, friends, and family members, he paints the most vivid and human portrait of the September 11 attacks yet.Beginning in the predawn hours of airports in the Northeast, we meet the ticket agents who unknowingly usher terrorists onto their flights, and the flight attendants inside the hijacked planes. In New York, first responders confront a scene of unimaginable horror at the Twin Towers. From a secret bunker under the White House, officials watch for incoming planes on radar. Aboard unarmed fighter jets in the air, pilots make a pact to fly into a hijacked airliner if necessary to bring it down. In the skies above Pennsylvania, civilians aboard United 93 make the ultimate sacrifice in their place. Then, as the day moves forward and flights are grounded nationwide, Air Force One circles the country alone, its passengers isolated and afraid.More than simply a collection of eyewitness testimonies, The Only Plane in the Sky is the historic narrative of how ordinary people grappled with extraordinary events in real time: the father and son caught on different ends of the impact zone; the firefighter searching for his wife who works at the World Trade Center; the operator of in-flight telephone calls who promises to share a passenger’s last words with his family; the beloved FDNY chaplain who bravely performs last rites for the dying, losing his own life when the Towers collapse; and the generals at the Pentagon who break down and weep when they are barred from trying to rescue their colleagues.At once a powerful tribute to the courage of everyday Americans and an essential addition to the literature of 9/11, The Only Plane in the Sky weaves together the unforgettable personal experiences of the men and women who found themselves caught at the center of an unprecedented human drama. The result is a unique, profound, and searing exploration of humanity on a day that changed the course of history, and all of our lives.