Pluto is entrenched in our cultural and emotional view of the cosmos, and Neil deGrasse Tyson, award-winning author and director of the Rose Center, is on a quest to discover why. He stood at the heart of the controversy over Pluto's demotion, and consequently Plutophiles have freely shared their opinions with him, including endless hate mail from third-graders. With his inimitable wit, Tyson delivers a minihistory of planets, describes the oversized characters of the people who study them, and recounts how America's favorite planet was ousted from the cosmic hub.

    But over the past decade, a wave of dramatic findings in the cutting-edge science of endurance has completely overturned our understanding of human limitation. Endure widely disseminates these findings for the first time: It’s the brain that dictates how far we can go—which means we can always push ourselves further.Hutchinson presents an overview of science’s search for understanding human fatigue, from crude experiments with electricity and frogs’ legs to sophisticated brain imaging technology. Going beyond the traditional mechanical view of human limits (like a car with a brick on its gas pedal, we go until the tank runs out of gas), he instead argues that a key element in endurance is how the brain responds to distress signals—whether heat, or cold, or muscles screaming with lactic acid—and reveals that we can train to improve brain response.An elite distance runner himself, Hutchinson takes us to the forefront of the new sports psychology—brain electrode jolts, computer-based training, subliminal messaging—and presents startling new discoveries enhancing the performance of athletes today and shows how anyone can utilize these tactics to bolster their own performance—and get the most out of their bodies.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

      We swim in freezing Arctic waters and piranha-infested rivers to test our limits. We swim for pleasure, for exercise, for healing. But humans, unlike other animals that are drawn to water, are not natural-born swimmers. We must be taught. Our evolutionary ancestors learned for survival; now, in the twenty-first century, swimming is one of the most popular activities in the world.Why We Swim is propelled by stories of Olympic champions, a Baghdad swim club that meets in Saddam Hussein’s palace pool, modern-day Japanese samurai swimmers, and even an Icelandic fisherman who improbably survives a wintry six-hour swim after a shipwreck. New York Times contributor Bonnie Tsui, a swimmer herself, dives into the deep, from the San Francisco Bay to the South China Sea, investigating what about water—despite its dangers—seduces us and why we come back to it again and again.

    Reisman weaves together stories about our insides with a unique perspective on life, culture, and the natural world.Jonathan Reisman, M.D.―a physician, adventure traveler and naturalist―brings readers on an odyssey navigating our insides like an explorer discovering a new world with  The Unseen Body . With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.Through his offbeat adventures in healthcare and travel, Reisman discovers new perspectives on the body: a trip to the Alaskan Arctic reveals that fat is not the enemy, but the hero; a stint in the Himalayas uncovers the boundary where the brain ends and the mind begins; and eating a sheep’s head in Iceland offers a lesson in empathy. By relating rich experiences in far-flung lands and among unique cultures back to the body’s inner workings, he shows how our organs live inextricably intertwined lives―an internal ecosystem reflecting the natural world around us.Reisman offers a new and deeply moving perspective, and helps us make sense of our bodies and how they work in a way readers have never before imagined.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    Eight years later, a schoolteacher who lived four miles away gave birth to a boy whose cherubic smile belied the fast growing tumors that soon riddled his face and chest. The doctors predicted he would not reach his first birthday. They were wrong, but that was only one of many surprises that would eventually come to light in Toms River, culminating in 2001 with a record legal settlement believed to top $35 million and an unprecedented government study confirming the existence of a long-suspected cluster of childhood cancer linked to polluted water and air. A detective story rooted in a scientific quest thousands of years old, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who would not keep silent.

    It would not stop there. Before long, the business had turned into a sprawling multinational conglomerate engaged in almost every conceivable aspect of criminal mayhem. Yachts carrying $100 million in cocaine. Safe houses in Hong Kong filled with gold bars. Shipments of methamphetamine from North Korea. Weapons deals with Iran. Mercenary armies in Somalia. Teams of hitmen in the Philippines. Encryption programs so advanced that the government could not break them.The man behind it all, pulling the strings from a laptop in Manila, was Paul Calder Le Roux—a reclusive programmer turned criminal genius who could only exist in the networked world of the twenty-first century, and the kind of self-made crime boss that American law enforcement had never imagined.For half a decade, DEA agents played a global game of cat-and-mouse with Le Roux as he left terror and chaos in his wake. Each time they came close, he would slip away. It would take relentless investigative work, and a shocking betrayal from within his organization, to catch him. And when he was finally caught, the story turned again, as Le Roux struck a deal to bring down his own organization and the people he had once employed.Award-winning investigative journalist Evan Ratliff spent four years piecing together this intricate puzzle, chasing LeRoux's empire and his shadowy henchmen around the world, conducting hundreds of interviews and uncovering thousands of documents. The result is a riveting, unprecedented account of a crime boss built by and for the digital age.Advance praise for The Mastermind“As directors, we spend countless hours imagining heightened plots and memorable characters that will leave a lasting impression on audiences. The true tale of obsession, genius, intrigue, and vengeance detailed in The Mastermind is as gripping and cinematic as anything we could endeavor to conjure up.”—Joe and Anthony Russo, directors of Captain America: The Winter Soldier, Captain America: Civil War, and Avengers: Infinity War“With his relentless and fearless reporting, Evan Ratliff has pried open a hidden world filled with high-tech gangsters and drug kingpins and double-crossers and stone-cold hitmen. The story is as fascinating as it is terrifying, and it is one that will hold you in its grip.”—David Grann, author of Killers of the Flower Moon“If truth is stranger than fiction, then The Mastermind is the truest book you’ll read this year. The only thing predictable about it is how quickly you’ll turn the pages.”—Noah Hawley, author of Before the Fall and creator of the TV series Fargo “This is a mesmerizing, absolutely bonkers story about a man as brilliant as he is villainous. You’ll find yourself sucked in, freaked out, and ultimately blown away by Ratliff's storytelling and tireless reporting. The Mastermind is a masterpiece.”—Nick Thompson, editor-in-chief, Wired

    But in recent decades, these claims have eroded, or even been disproven outright, by a revolution in the study of animal cognition. Take the way octopuses use coconut shells as tools; elephants that classify humans by age, gender, and language; or Ayumu, the young male chimpanzee at Kyoto University whose flash memory puts that of humans to shame. Based on research involving crows, dolphins, parrots, sheep, wasps, bats, whales, and of course chimpanzees and bonobos, Frans de Waal explores both the scope and the depth of animal intelligence. He offers a firsthand account of how science has stood traditional behaviorism on its head by revealing how smart animals really are, and how we’ve underestimated their abilities for too long.People often assume a cognitive ladder, from lower to higher forms, with our own intelligence at the top. But what if it is more like a bush, with cognition taking different forms that are often incomparable to ours? Would you presume yourself dumber than a squirrel because you’re less adept at recalling the locations of hundreds of buried acorns? Or would you judge your perception of your surroundings as more sophisticated than that of a echolocating bat? De Waal reviews the rise and fall of the mechanistic view of animals and opens our minds to the idea that animal minds are far more intricate and complex than we have assumed. De Waal’s landmark work will convince you to rethink everything you thought you knew about animal—and human—intelligence.

    It is a place where life and death meet. A place where some families celebrate the most improbable of victories while others face the most devastating of losses. A place where what matters the most in this life is revealed. Trauma Room Two is just such a place. In this collection of short stories, Dr. Green takes the reader inside the hidden emotional landscape of emergency medicine. Based on fifteen years of experience as an ER physician, he reveals the profound moments that often occur in emergency rooms for patients, their families, and the staff that work there.

    Learn how to identify the strategies and the dosages for using food to transform your resilience and health in EAT TO BEAT DISEASE.We have radically underestimated our body's power to transform and restore our health. Pioneering physician scientist, Dr. William Li, empowers readers by showing them the evidence behind over 200 health-boosting foods that can starve cancer, reduce your risk of dementia, and beat dozens of avoidable diseases. EAT TO BEAT DISEASE isn't about what foods to avoid, but rather is a life-changing guide to the hundreds of healing foods to add to your meals that support the body's defense systems, including:PlumsCinnamonJasmine teaRed wine and beerBlack BeansSan Marzano tomatoesOlive oilPacific oystersCheeses like Jarlsberg, Camembert and cheddarSourdough breadThe book's plan shows you how to integrate the foods you already love into any diet or health plan to activate your body's health defense systems-Angiogenesis, Regeneration, Microbiome, DNA Protection, and Immunity-to fight cancer, diabetes, cardiovascular, neurodegenerative, and autoimmune diseases, and other debilitating conditions.Both informative and practical, EAT TO BEAT DISEASE explains the science of healing and prevention, the strategies for using food to actively transform health, and points the science of well-being and disease prevention in an exhilarating new direction.

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.