In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

     This area was dangerous and many who had ventured there alone had never returned. But slowly over the course of this century settlers continued to push further west until regions such as West Virginia were populated with more and more adventurous young men and women. The settlement of these lands did not occur without difficulties and colonizers frequently came into conflict with the local Native American populations. Wills De Hass’s remarkable book History of the Early Settlement and Indian Wars of West Virginia is a fascinating history of how the lands of the west were first settled by white emigrants in the eighteenth century and how these settlers came into frequent strife with the Native American tribes who had previously lived there. Beginning with Columbus’ discovery of this great continent Wills De Hass charts the colonization of this expansive land. He records with brilliant detail the early encounters that Europeans had with the men and women that they found already living across the region and explains how various nations from across the Atlantic made their first tentative footholds on this newly discovered land. De Hass records how settlers were not only conflict with Native Americans but also with each other as this region descended into war, firstly during the French and Indian War and shortly afterwards during the American War of Independence. Particularly fascinating throughout the book are the biographical sketches of various well-known frontiersmen who were particularly influential in the Ohio Valley and northwestern Virginia. This book is perfect for anyone interested in the early settlement of western regions prior to 1795 and how this area was frequently in conflict as settlers attempted to assert their rights against the wishes of the Native American populations. Wills de Hass was a lecturer and writer on archaeological and historical subjects. His book History of the Early Settlement and Indian Wars of Western Virginia was first published in 1851 and De Hass passed away 1910.

    Bill Bass, one of the world's leading forensic anthropologists, gained international attention when he built a forensic lab like no other: The Body Farm. Now, this master scientist unlocks the gates of his lab to reveal his most intriguing cases-and to revisit the Lindbergh kidnapping and murder, fifty years after the fact.

    In her early twenties, Steingraber was afflicted with cancer, a disease that has afflicted other members of her adoptive family. Writing from the twin perspectives of a survivor and a concerned scientist, she traces the high incidence of cancer and the terrifying concentrations of environmental toxins in her native rural Illinois. She goes on to show similar correlation in other communities, such as Boston and Long Island, and throughout the United States, where cancer rates have risen alarmingly since mid-century. At once a deeply moving personal document and a groundbreaking work of scientific detection, Living Downstream will be a touchstone for generations, reminding us of the intimate connection between the health of our bodies and the integrity of our air, land, and water. "By skillfully weaving a strong personal drama with thorough scientific research, Steingraber tells a compelling story....Well worth reading."--Washington Post

    Extracted from opium, the sap of the poppy, this popular drug was welcomed into the homes of rich and poor alike, in the guise of medicinal uses in the form of laudanum and opium elixirs, and as pure, undisguised morphine.Laudanum contained opium, saffron, cinnamon and alcohol. In the spirit of 19th century progress, other opium concoctions were created and a whole industry in quackery erupted. In both Britain and North America, opium was mixed with everything imaginable: mercury, hashish, cayenne pepper, ether, chloroform, belladonna and whisky, sherry, wine and brandy.In the Arms of Morpheus examines how the drinking of laudanum for medical reasons developed and how it became an everyday safeguard against pain, poverty, and boredom. Opium eating was catapulted into fame by the confessions of Thomas De Quincy and insinuated itself into the lives and works of writers such as Louisa May Alcott, Lord Byron, Shelley, Elizabeth Barrett Browning, John Keats, the Brontes, Samuel Taylor Coleridge and many others.Thoroughly researched and copiously illustrated with photographs, engravings, advertisements, movie stills, pulp magazine and dime novel covers and paraphernalia, In the Arms of Morpheus continues the history of opium's emergence as an omnipresent and sometimes devastating influence.

    In this inspiring book, internationally renowned cardiologist Andrzej Szczeklik draws deeply on our humanistic heritage to describe the artistry and the mystery of being a doctor. Moving between examples ancient and contemporary, mythological and scientific, Catharsis explores how medicine and art share common roots and pose common challenge.As Szczeklik explores such subjects as the mysteries of the heart rhythm, the secret history of pain relief, the enigmatic logic of epidemics, near-death or out-of-body experiences, and many more, he skillfully weaves together classical literature, the history of medicine, and moving anecdotes from his own clinical experiences. The result is a life-affirming book that will enrich the healing work of patients and doctors alike and make an invaluable contribution to our still-expanding vision of the art of medicine.“Drawing on mathematical ideas, physics, music, mythology, clinical science and clinical practice, Szczeklik never forces the issues or compels. . . . He approaches the questions of pain, suffering and death that confront the doctor daily and that the world regards as ‘terrible, futile, and destructive.’ Here he stresses the immense value of the experienced doctor in helping patients in the loneliness of pain.”—Niall O'Higgins, Times Higher Education Supplement

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Nick."Dr. Nichopoulos spent a decade with Elvis on the road and at Graceland, trying to maintain the precarious health of one of the world’s greatest entertainers. But on August 16, 1977, he found himself in the ambulance with Elvis on that fateful last trip to the ER. He signed the death certificate.From that day forward, Dr. Nick became the focus of a media witch hunt that threatened his life and all but destroyed his professional reputation. Now, for the first time, Dr. Nick reveals the true story behind Elvis’s drug use and final days—not the version formed by years of tabloid journalism and gross speculation. Put aside what you’ve learned about Elvis’s final days and get ready to understand for the first time the inner workings of “the king of rock n’ roll.”

    But it took a team of Oxford scientists headed by Howard Florey and Ernst Chain four more years to develop it as the first antibiotic, and the most important family of drugs in the twentieth century. At once the world was transformed—major bacterial scourges such as blood poisoning and pneumonia, scarlet fever and diphtheria, gonorrhea and syphilis were defeated as penicillin helped to foster not only a medical revolution but a sexual one as well. In his wonderfully engaging book, acclaimed author Eric Lax tells the real story behind the discovery and why it took so long to develop the drug. He reveals the reasons why credit for penicillin was misplaced, and why this astonishing achievement garnered a Nobel Prize but no financial rewards for Alexander Fleming, Florey, and his team. The Mold in Dr. Florey’s Coat is the compelling story of the passage of medicine from one era to the next and of the eccentric individuals whose participation in this extraordinary accomplishment has, until now, remained largely unknown.

    To Hogshire, pills are the quintessence of Western culture, embodying our desires, fears, ambivalence about life and death, health and freedom -- as well as our faith in the quick fix.Hogshire muses on pill naming and marketing, presents up-to-the-minute pill news, and discusses celebrities and their pills of choice. Along the way, he provides histories of drug manufacturers and examines how pills are the product of decades of scientific exploration and the result of billions of dollars in research.

    These bacteria are everywhere: in and on our bodies, in homes, schools, hospitals, crowded airplanes, day-care centers. And, as The Killers Within makes frighteningly clear, so far the bacteria are winning.

    Michelle Harrison kept throughout her months of residency in OB/GYN--draws us into the serious and thrilling work of delivering new life into the world...and into Dr. Harrison's own struggle to reconcile the often startling difference between patient care and hospital convenience. She writes about her patients, for whom she never had quite enough time; about her colleagues, with whom she did not always agree; about the excitement of learning new procedures; about the pressures that never let up. She brings us as close as most of us are likely to come to the intense inner life of a big hospital."

    In 1985 Hans von Ohain, the scientist who pioneered Nazi Germany's efforts to build a jet plane, posed the question: 'Would World War II have occured if the Luftwaffe knew it faced operational British jets instead of Spitfires?' He immediately answered, 'I, for one, think not.'Frank Whittle, working-class outsider and self-taught enthusiast, had worked out the blueprint of a completely new type of engine in 1929, only for his ideas to be blocked by bureaucratic opposition until the outbreak of war in 1939. The importance of his work was recognized too late by the government for his revolutionary engine to play a major part in World War II. After the war Whittle's dream of civilian jet-powered aircraft became a reality and Britain enjoyed a golden age of 1950's jet-powered flight.Drawing on Whittle's extensive private papers, Campbell-Smith tells the story of a stoic and overlooked British hero, a tantalizing tale of 'what might have been'.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.