The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    This is the story of a fateful year that prefigured the events of 1776.In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protegee; Samuel Adams.During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. Inoculation led to vaccination, one of the most profound medical discoveries in history. Public outrage forced Boylston into hiding, and Mather's house was firebombed.A political fever also raged. Elisha Cooke was challenging the Crown for control of the colony and finally forced Royal Governor Samuel Shute to flee Massachusetts. Samuel Adams and the Patriots would build on this to resist the British in the run-up to the American Revolution. And a bold young printer James Franklin (who was on the wrong side of the controversy on inoculation), launched America's first independent newspaper and landed in jail. His teenage brother and apprentice, Benjamin Franklin, however, learned his trade in James' shop and became a father of the Independence movement.One by one, the atmosphere in Boston in 1721 simmered and ultimately boiled over, leading to the full drama of the American Revolution.

    What ended in one atrocity began with another: the savage military takeover of China's capital city, which quickly became known as the Rape of Nanking. The Japanese Army's conduct from December 1937 to February 1938 constitutes one of the most barbarous events not just of the war but of the century. The violence was documented at the time and then redocumented during the war crimes trial in Tokyo after the war. This book brings together materials from both moments to provide the first comprehensive dossier of primary sources on the Rape.Part 1, "The Records," includes two sources written as the Rape was underway. The first is a long set of documents produced by the International Committee for the Nanking Safety Zone, a group of foreigners who strove to protect the Chinese residents. The second is a series of letters that American surgeon Dr. Robert Wilson wrote for his family during the same period. These letters are published here for the first time.The evidence compiled by the International Committee and its members would be decisive for the indictments against Japanese leaders at the International Military Tribunal for the Far East in Tokyo. Part 2, "The Judgments," reprints portions of the tribunal's 1948 judgment dealing with the Rape of Nanking, its judicial consequences, and sections of the dissenting judgment of Justice Radhabinod Pal.These contemporary records and judgments create an intimate firsthand account of the Rape of Nanking. Together they are intended to stimulate deeper reflection than previously possible on how and why we assess and assign the burden of war guilt.Timothy Brook is Professor of Chinese History and Associate Director of the Joint Centre for Asia Pacific Studies, University of Toronto, and is coeditor of Nation Work: Asian Elites and National Identities and Cultureand Economy: The Shaping of Capitalism in Eastern Asia, both published by the University of Michigan Press.

    But we should--even those of us who take care of our business in pristine, sanitary conditions. For it's not only in developing countries that human waste is a major public health threat: population growth is taxing even the most advanced sewage systems, and the disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, 1.95 million people have no access to an indoor toilet. Yet the subject remains unmentionable."The Big Necessity "takes aim at the taboo, revealing everything that matters about how people do--and don't--deal with their own waste. Moving from the deep underground sewers of Paris, London, and New York--an infrastructure disaster waiting to happen--to an Indian slum where ten toilets are shared by 60,000 people, Rose George stops along the way to explore the potential saviors: China's five million biogas digesters, which produce energy from waste; the heroes of third world sanitation movements; the inventor of the humble Car Loo; and the U.S. Army's personal lasers used by soldiers to zap their feces in the field.With razor-sharp wit and crusading urgency, mixing levity with gravity, Rose George has turned the subject we like to avoid into a cause with the most serious of consequences.

    We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

     Elinor Cleghorn became an unwell woman ten years ago. She was diagnosed with an autoimmune disease after a long period of being told her symptoms were anything from psychosomatic to a possible pregnancy. As Elinor learned to live with her unpredictable disease she turned to history for answers, and found an enraging legacy of suffering, mystification, and misdiagnosis.In Unwell Women, Elinor Cleghorn traces the almost unbelievable history of how medicine has failed women by treating their bodies as alien and other, often to perilous effect. The result is an authoritative and groundbreaking exploration of the relationship between women and medical practice, from the wandering womb of Ancient Greece to the rise of witch trials across Europe, and from the dawn of hysteria as a catchall for difficult-to-diagnose disorders to the first forays into autoimmunity and the shifting understanding of hormones, menstruation, menopause, and conditions like endometriosis.Packed with character studies and case histories of women who have suffered, challenged, and rewritten medical orthodoxy--and the men who controlled their fate--this is a revolutionary examination of the relationship between women, illness, and medicine. With these case histories, Elinor pays homage to the women who suffered so strides could be made, and shows how being unwell has become normalized in society and culture, where women have long been distrusted as reliable narrators of their own bodies and pain. But the time for real change is long overdue: answers reside in the body, in the testimonies of unwell women--and their lives depend on medicine learning to listen.

    The Nazis hated Sigmund Freud with a particular vehemence: they detested his "soul-destroying glorification of the instinctual life." Here Mark Edmundson traces Hitler and Freud's oddly converging lives, then zeroes in on Freud's last two years, during which, with the help of Marie Bonaparte, he was at last rescued from Vienna and brought safely to London. There he was honored as he never had been during his long, controversial life. At the same time he endured the last of more than thirty operations for cancer of the jaw. Confronting certain death, Freud, in typical fashion, did not let fame make him complacent, but instead wrote his most provocative book, Moses and Monotheism, in which he questioned the legacy of the greatest Jewish leader. Focusing on Freud's last two years, Edmundson is able to probe Freud's ideas about death, and also about the human proclivity to embrace fascism in politics and fundamentalism in religion. Edmundson suggests new and important ways to view Freud's legacy, at a time when these forces are once again shaping world events.

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

    Mocked and scorned by his contemporaries, Lay was unflinching in his opposition to slavery, often performing colorful guerrilla theater to shame slave masters, insisting that human bondage violated the fundamental principles of Christianity. He drew on his ideals to create a revolutionary way of life, one that embodied the proclamation "no justice, no peace."Lay was born in 1682 in Essex, England. His philosophies, employments, and places of residence--spanning England, Barbados, Philadelphia, and the open seas--were markedly diverse over the course of his life. He worked as a shepherd, glove maker, sailor, and bookseller. His worldview was an astonishing combination of Quakerism, vegetarianism, animal rights, opposition to the death penalty, and abolitionism.While in Abington, Philadelphia, Lay lived in a cave-like dwelling surrounded by a library of two hundred books, and it was in this unconventional abode where he penned a fiery and controversial book against bondage, which Benjamin Franklin published in 1738. Always in motion and ever confrontational, Lay maintained throughout his life a steadfast opposition to slavery and a fierce determination to make his fellow Quakers denounce it, which they finally began to do toward the end of his life.With passion and historical rigor, Rediker situates Lay as a man who fervently embodied the ideals of democracy and equality as he practiced a unique concoction of radicalism nearly three hundred years ago. Rediker resurrects this forceful and prescient visionary, who speaks to us across the ages and whose innovative approach to activism is a gift, transforming how we consider the past and how we might imagine the future.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    Although he covers the broad sweep of the American experience of epidemics from yellow fever to COVID-19, he is especially timely in his exploration of the legal background to the current disaster of the American response to the coronavirus. A thought-provoking, readable, and important work.”—Frank Snowden, author of Epidemics and Society From yellow fever to smallpox to polio to AIDS to COVID-19, epidemics have prompted Americans to make choices and answer questions about their basic values and their laws. In five concise chapters, historian John Fabian Witt traces the legal history of epidemics, showing how infectious disease has both shaped, and been shaped by, the law. Arguing that throughout American history legal approaches to public health have been liberal for some communities and authoritarian for others, Witt shows us how history’s answers to the major questions brought up by previous epidemics help shape our answers today: What is the relationship between individual liberty and the common good? What is the role of the federal government, and what is the role of the states? Will long-standing traditions of government and law give way to the social imperatives of an epidemic? Will we let the inequities of our mixed tradition continue?

    We own radiation-emitting phones, regularly get diagnostic x-rays, such as mammograms, and submit to full-body security scans at airports. We worry and debate about the proliferation of nuclear weapons and the safety of nuclear power plants. But how much do we really know about radiation? And what are its actual dangers? An accessible blend of narrative history and science, Strange Glow describes mankind's extraordinary, thorny relationship with radiation, including the hard-won lessons of how radiation helps and harms our health. Timothy Jorgensen explores how our knowledge of and experiences with radiation in the last century can lead us to smarter personal decisions about radiation exposures today.Jorgensen introduces key figures in the story of radiation--from Wilhelm Roentgen, the discoverer of x-rays, and pioneering radioactivity researchers Marie and Pierre Curie, to Thomas Edison and the victims of the recent Fukushima Daiichi nuclear power plant accident. Tracing the most important events in the evolution of radiation, Jorgensen explains exactly what radiation is, how it produces certain health consequences, and how we can protect ourselves from harm. He also considers a range of practical scenarios such as the risks of radon in our basements, radiation levels in the fish we eat, questions about cell-phone use, and radiation's link to cancer. Jorgensen empowers us to make informed choices while offering a clearer understanding of broader societal issues.Investigating radiation's benefits and risks, Strange Glow takes a remarkable look at how, for better or worse, radiation has transformed our society.

    But New Yorkers don't give it much attention. They leave their trash on the curb or drop it in a litter basket, and promptly forget about it. And why not? On a schedule so regular you could almost set your watch by it, someone always comes to take it away.But who, exactly, is that someone? And why is he—or she—so unknown?In Picking Up, the anthropologist Robin Nagle introduces us to the men and women of New York City's Department of Sanitation and makes clear why this small army of uniformed workers is the most important labor force on the streets. Seeking to understand every aspect of the Department's mission, Nagle accompanied crews on their routes, questioned supervisors and commissioners, and listened to story after story about blizzards, hazardous wastes, and the insults of everyday New Yorkers. But the more time she spent with the DSNY, the more Nagle realized that observing wasn't quite enough—so she joined the force herself. Driving the hulking trucks, she obtained an insider's perspective on the complex kinships, arcane rules, and obscure lingo unique to the realm of sanitation workers.Nagle chronicles New York City's four-hundred-year struggle with trash, and traces the city's waste-management efforts from a time when filth overwhelmed the streets to the far more rigorous practices of today, when the Big Apple is as clean as it's ever been.Throughout, Nagle reveals the many unexpected ways in which sanitation workers stand between our seemingly well-ordered lives and the sea of refuse that would otherwise overwhelm us. In the process, she changes the way we understand cities—and ourselves within them.

    More than any other major national leader, he personifies his country in the eyes of the outside world, and dominates Western media coverage of it to an extraordinary extent. In Russia itself, he is likewise the centre of attention for detractors and supporters alike. But as Tony Wood argues, this overwhelming focus on the president and his personality means that we understand Russia less than we ever did before. Too much attention is paid to the man, and not enough to the country outside the Kremlin's walls. In this timely and provocative analysis, Wood looks beyond Putin to explore the profound changes Russia has undergone since 1991. In the process, he challenges many of the common assumptions made about contemporary Russia. Though commonly viewed as an ominous return to Soviet authoritarianism, Putin's rule should instead be seen as a direct continuation of Yeltsin's in the 1990s. And though many of Russia's problems today are blamed on legacies of the Soviet past, Wood argues that the core features of Putinism--a predatory, authoritarian elite presiding over a vastly unequal society--are integral to the system set in place after the fall of Communism.What kind of country has emerged from Russia's post-Soviet transformations, and where might it go in future? Russia Without Putin culminates in an arresting analysis of the country's foreign policy--identifying the real power dynamics behind its escalating clashes with the West--and with reflections on the paths Russia might take in the 21st century.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.