This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You'll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what's going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!

    Jon has done a wonderful job of updating the material. I am very impressed at how fresh the new examples seem." - Steve McConnell, author, Code CompleteWhen programmers list their favorite books, Jon Bentley's collection of programming pearls is commonly included among the classics. Just as natural pearls grow from grains of sand that irritate oysters, programming pearls have grown from real problems that have irritated real programmers. With origins beyond solid engineering, in the realm of insight and creativity, Bentley's pearls offer unique and clever solutions to those nagging problems. Illustrated by programs designed as much for fun as for instruction, the book is filled with lucid and witty descriptions of practical programming techniques and fundamental design principles. It is not at all surprising that Programming Pearls has been so highly valued by programmers at every level of experience. In this revision, the first in 14 years, Bentley has substantially updated his essays to reflect current programming methods and environments. In addition, there are three new essays on (1) testing, debugging, and timing; (2) set representations; and (3) string problems. All the original programs have been rewritten, and an equal amount of new code has been generated. Implementations of all the programs, in C or C++, are now available on the Web.What remains the same in this new edition is Bentley's focus on the hard core of programming problems and his delivery of workable solutions to those problems. Whether you are new to Bentley's classic or are revisiting his work for some fresh insight, this book is sure to make your own list of favorites.

    This long-awaited revision contains changes throughout the text. There are new implementations of most of the major programming systems in the book, including the interpreters and compilers, and the authors have incorporated many small changes that reflect their experience teaching the course at MIT since the first edition was published. A new theme has been introduced that emphasizes the central role played by different approaches to dealing with time in computational models: objects with state, concurrent programming, functional programming and lazy evaluation, and nondeterministic programming. There are new example sections on higher-order procedures in graphics and on applications of stream processing in numerical programming, and many new exercises. In addition, all the programs have been reworked to run in any Scheme implementation that adheres to the IEEE standard.

    Each chapter is relatively self-contained and can be used as a unit of study. The algorithms are described in English and in a pseudocode designed to be readable by anyone who has done a little programming. The explanations have been kept elementary without sacrificing depth of coverage or mathematical rigor.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    You will be able to look over the shoulder of major coding and design experts to see problems through their eyes.This is not simply another design patterns book, or another software engineering treatise on the right and wrong way to do things. The authors think aloud as they work through their project's architecture, the tradeoffs made in its construction, and when it was important to break rules. Beautiful Code is an opportunity for master coders to tell their story. All author royalties will be donated to Amnesty International.

    Now that machine learning is thriving, even programmers who know close to nothing about this technology can use simple, efficient tools to implement programs capable of learning from data. This practical book shows you how.By using concrete examples, minimal theory, and two production-ready Python frameworks—Scikit-Learn and TensorFlow—author Aurélien Géron helps you gain an intuitive understanding of the concepts and tools for building intelligent systems. You’ll learn how to use a range of techniques, starting with simple Linear Regression and progressing to Deep Neural Networks. If you have some programming experience and you’re ready to code a machine learning project, this guide is for you.This hands-on book shows you how to use:Scikit-Learn, an accessible framework that implements many algorithms efficiently and serves as a great machine learning entry pointTensorFlow, a more complex library for distributed numerical computation, ideal for training and running very large neural networksPractical code examples that you can apply without learning excessive machine learning theory or algorithm details

    But what if you could have your computer do them for you?In "Automate the Boring Stuff with Python," you'll learn how to use Python to write programs that do in minutes what would take you hours to do by hand no prior programming experience required. Once you've mastered the basics of programming, you'll create Python programs that effortlessly perform useful and impressive feats of automation to: Search for text in a file or across multiple filesCreate, update, move, and rename files and foldersSearch the Web and download online contentUpdate and format data in Excel spreadsheets of any sizeSplit, merge, watermark, and encrypt PDFsSend reminder emails and text notificationsFill out online formsStep-by-step instructions walk you through each program, and practice projects at the end of each chapter challenge you to improve those programs and use your newfound skills to automate similar tasks.Don't spend your time doing work a well-trained monkey could do. Even if you've never written a line of code, you can make your computer do the grunt work. Learn how in "Automate the Boring Stuff with Python.""

    "More concretely," the authors explain, "it is the controlled manipulation of mathematical formulas, using a collection of techniques for solving problems."

    In this book, you’ll learn how many of the most fundamental data science tools and algorithms work by implementing them from scratch. If you have an aptitude for mathematics and some programming skills, author Joel Grus will help you get comfortable with the math and statistics at the core of data science, and with hacking skills you need to get started as a data scientist. Today’s messy glut of data holds answers to questions no one’s even thought to ask. This book provides you with the know-how to dig those answers out. Get a crash course in Python Learn the basics of linear algebra, statistics, and probability—and understand how and when they're used in data science Collect, explore, clean, munge, and manipulate data Dive into the fundamentals of machine learning Implement models such as k-nearest Neighbors, Naive Bayes, linear and logistic regression, decision trees, neural networks, and clustering Explore recommender systems, natural language processing, network analysis, MapReduce, and databases

    With this hands-on guide, you'll learn how to write effective, idiomatic Python code by leveraging its best and possibly most neglected features. Author Luciano Ramalho takes you through Python's core language features and libraries, and shows you how to make your code shorter, faster, and more readable at the same time.Many experienced programmers try to bend Python to fit patterns they learned from other languages, and never discover Python features outside of their experience. With this book, those Python programmers will thoroughly learn how to become proficient in Python 3.This book covers:Python data model: understand how special methods are the key to the consistent behavior of objectsData structures: take full advantage of built-in types, and understand the text vs bytes duality in the Unicode ageFunctions as objects: view Python functions as first-class objects, and understand how this affects popular design patternsObject-oriented idioms: build classes by learning about references, mutability, interfaces, operator overloading, and multiple inheritanceControl flow: leverage context managers, generators, coroutines, and concurrency with the concurrent.futures and asyncio packagesMetaprogramming: understand how properties, attribute descriptors, class decorators, and metaclasses work"

    Cryptography is vital to keeping information safe, in an era when the formula to do so becomes more and more challenging. Written by a team of world-renowned cryptography experts, this essential guide is the definitive introduction to all major areas of cryptography: message security, key negotiation, and key management. You'll learn how to think like a cryptographer. You'll discover techniques for building cryptography into products from the start and you'll examine the many technical changes in the field.After a basic overview of cryptography and what it means today, this indispensable resource covers such topics as block ciphers, block modes, hash functions, encryption modes, message authentication codes, implementation issues, negotiation protocols, and more. Helpful examples and hands-on exercises enhance your understanding of the multi-faceted field of cryptography.An author team of internationally recognized cryptography experts updates you on vital topics in the field of cryptography Shows you how to build cryptography into products from the start Examines updates and changes to cryptography Includes coverage on key servers, message security, authentication codes, new standards, block ciphers, message authentication codes, and more Cryptography Engineering gets you up to speed in the ever-evolving field of cryptography.

    Drawing heavily on the author's own real-world experiences, the book stresses design and analysis. Coverage is divided into two parts, the first being a general guide to techniques for the design and analysis of computer algorithms. The second is a reference section, which includes a catalog of the 75 most important algorithmic problems. By browsing this catalog, readers can quickly identify what the problem they have encountered is called, what is known about it, and how they should proceed if they need to solve it. This book is ideal for the working professional who uses algorithms on a daily basis and has need for a handy reference. This work can also readily be used in an upper-division course or as a student reference guide. THE ALGORITHM DESIGN MANUAL comes with a CD-ROM that contains: * a complete hypertext version of the full printed book. * the source code and URLs for all cited implementations. * over 30 hours of audio lectures on the design and analysis of algorithms are provided, all keyed to on-line lecture notes.

    It covers the basics of computer programming, including variables and values, functions, conditionals and control flow, program development and debugging. Later chapters cover basic algorithms and data structures.

    And through CODE, we see how this ingenuity and our very human compulsion to communicate have driven the technological innovations of the past two centuries. Using everyday objects and familiar language systems such as Braille and Morse code, author Charles Petzold weaves an illuminating narrative for anyone who’s ever wondered about the secret inner life of computers and other smart machines. It’s a cleverly illustrated and eminently comprehensible story—and along the way, you’ll discover you’ve gained a real context for understanding today’s world of PCs, digital media, and the Internet. No matter what your level of technical savvy, CODE will charm you—and perhaps even awaken the technophile within.