David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    It wiped out one-third of Europe's population, taking some 20 million lives. And yet, most of what we know about it is wrong. The details of the Plague etched in the minds of terrified schoolchildren—the hideous black welts, the high fever, and the awful end by respiratory failure—are more or less accurate. But what the Plague really was and how it made history remain shrouded in a haze of myths.Now, Norman Cantor, the premier historian of the Middle Ages, draws together the most recent scientific discoveries and groundbreaking historical research to pierce the mist and tell the story of the Black Death as a gripping, intimate narrative.

    Carried along the mighty Mississippi River, it ravaged towns from New Orleans to St. Louis. New York City lost 2,000 lives in one year alone. It even forced the nation's capital to relocate from Philadelphia to Washington, DC. "The American Plague" reveals the true story of yellow fever, recounting Memphis, Tennessee's near-destruction and resurrection from the epidemic-and the four men who changed medical history with their battle against an invisible foe that remains a threat to this very day.

    Soon young Rodney followed in Dad's stumbling steps, beginning a lifetime of alcohol abuse.King had been drinking the night of March 3, 1991, when he engaged in a high-speed chase with the LAPD, who finally pulled him over. What happened next shocked the nation. A group of officers brutally beat King with their metal batons, Tasered and kicked him into submission--all caught on videotape by a nearby resident. The infamous Rodney King Incident was born when this first instance of citizen surveillance revealed a shocking moment of police brutality, a horrific scene that stunned and riveted the nation via the evening news. Racial tensions long smoldering in L.A. ignited into a firestorm thirteen months later when four white officers were acquitted by a mostly white jury. Los Angeles was engulfed in flames as people rioted in the streets. More than fifty people were dead, hundreds were hospitalized, and countless homes and businesses were destroyed.King's plaintive question, "Can we all just get along?" became a sincere but haunting plea for reconciliation that reflected the heartbreak and despair caused by America's racial discord in the early 1990s.While Rodney King is now an icon, he is by no means an angel. King has had run-ins with the law and continues a lifelong struggle with alcohol addiction. But King refuses to be bitter about the crippling emotional and physical damage that was inflicted upon him that night in 1991. While this nation has made strides during those twenty years to heal, so has Rodney King, and his inspiring story can teach us all lessons about forgiveness, redemption, and renewal, both as individuals and as a nation.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    The selections in this anthology show how Orwell developed as writer and as thinker; inevitably, too, they reflect and illuminate the history of the time of troubles in which he lived and worked. “A magnificent tribute to the probity, consistency and insight of Orwell’s topical writings” (Alfred Kazin). Introduction by Richard H. Rovere.

    Among all aspects of Jefferson's renowned life, it was perhaps the most hotly contested topic. The publication of Thomas Jefferson and Sally Hemings intensified this debate by identifying glaring inconsistencies in many noted scholars' evaluations of the existing evidence. In this study, Gordon-Reed assembles a fascinating and convincing argument: not that the alleged thirty-eight-year liaison necessarily took place but rather that the evidence for its taking place has been denied a fair hearing.Friends of Jefferson sought to debunk the Hemings story as early as 1800, and most subsequent historians and biographers followed suit, finding the affair unthinkable based upon their view of Jefferson's life, character, and beliefs. Gordon-Reed responds to these critics by pointing out numerous errors and prejudices in their writings, ranging from inaccurate citations, to impossible time lines, to virtual exclusions of evidence--especially evidence concerning the Hemings family. She demonstrates how these scholars may have been misguided by their own biases and may even have tailored evidence to serve and preserve their opinions of Jefferson. This updated edition of the book also includes an afterword in which the author comments on the DNA study that provided further evidence of a Jefferson and Hemings liaison.Possessing both a layperson's unfettered curiosity and a lawyer's logical mind, Annette Gordon-Reed writes with a style and compassion that are irresistible. Each chapter revolves around a key figure in the Hemings drama, and the resulting portraits are engrossing and very personal. Gordon-Reed also brings a keen intuitive sense of the psychological complexities of human relationships--relationships that, in the real world, often develop regardless of status or race. The most compelling element of all, however, is her extensive and careful research, which often allows the evidence to speak for itself. Thomas Jefferson and Sally Hemings: An American Controversy is the definitive look at a centuries-old question that should fascinate general readers and historians alike.

    He drops out of architecture school and decides to travel to Vals in the Swiss Alps, home to a thermal springs complex located deep inside a mountain. The complex, designed by architect Peter Zumthor, had been the subject of Pierre's thesis. The mountain holds many mysteries; it was said to have a mouth that periodically swallowed people up. Pierre, sketchbook in hand, is drawn to the enigmatic powers of the mountain and its springs, and attempts to uncover the truth behind them in the secret rooms he discovers deep within the complex. But he finds his match in a man named Valeret who is similarly obsessed, and who'd like nothing more than to eliminate his competitor.Gorgeously illustrated, Swimming in Darkness is an intriguing, noirish graphic novel about uncovering the powerful secrets of the natural world.

    The uniquely multicultural nature of life on a seventeenth-century Barbadan sugar plantation--defined by a mixture of English, American Indian, and African ways and folklore--indelibly shaped the young Tituba's world and the mental images she brought with her to Massachusetts.Breslaw divides Tituba's story into two parts. The first focuses on Tituba's roots in Barbados, the second on her life in the New World. The author emphasizes the inextricably linked worlds of the Caribbean and the North American colonies, illustrating how the Puritan worldview was influenced by its perception of possessed Indians. Breslaw argues that Tituba's confession to practicing witchcraft clearly reveals her savvy and determined efforts to protect herself by actively manipulating Puritan fears. This confession, perceived as evidence of a diabolical conspiracy, was the central agent in the cataclysmic series of events that saw 19 people executed and over 150 imprisoned, including a young girl of 5.A landmark contribution to women's history and early American history, Tituba, Reluctant Witch of Salem sheds new light on one of the most painful episodes in American history, through the eyes of its most crucial participant.

    Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.

    When we weren't sheltering in place, we were advised to wear masks, wash our hands, and practice social distancing. We watched in horror as medical personnel worked around the clock to care for the sick and dying. Businesses were shuttered, travel stopped, workers were furloughed, and markets dropped. And people continued to die.Amid all this uncertainty, writers and artists from around the world continued to create comics, commenting directly on how individuals, societies, governments, and markets reacted to the worldwide crisis. COVID Chronicles: A Comics Anthology collects more than sixty such short comics from a diverse set of creators, including indie powerhouses, mainstream artists, Ignatz and Eisner Award winners, and media cartoonists. In narrative styles ranging from realistic to fantastic, they tell stories about adjusting to working from home, homeschooling their kids, missing birthdays and weddings, and being afraid just to leave the house. They probe the failures of government leaders and the social safety net. They dig into the racial bias and systemic inequities that this pandemic helped bring to light. We see what it's like to get the virus and live to tell about it, or to stand by helplessly as a loved one passes.At times heartbreaking and at others hopeful and humorous, these comics express the anger, anxiety, fear, and bewilderment we feel in the era of COVID-19. Above all, they highlight the power of art and community to help us make sense of a world in crisis, reminding us that we are truly all in this together.The comics in this collection have been generously donated by their creators. A portion of the the proceeds from the sale of this volume are being donated by the publisher to the Book Industry Charitable Foundation (Binc) in support of comics shops, bookstores, and their employees who have been adversely affected by the pandemic.

     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    Forty-five million called him emperor, and he commanded a nation that was the richest, most cultured, and advanced on earth. No army could stand against his impeccably trained, brilliantly led forces, and his continued sweep across Europe seemed inevitable. Early that year, bolstered by his successes, Napoleon turned his attentions toward Moscow, helming the largest invasion in human history. Surely, Tsar Alexander’s outnumbered troops would crumble against this mighty force. But another powerful and ancient enemy awaited Napoleon’s men in the Russian steppes. Virulent and swift, this microscopic foe would bring the emperor to his knees. Even as the Russians retreated before him in disarray, Napoleon found his army disappearing, his frantic doctors powerless to explain what had struck down a hundred thousand soldiers. The emperor’s vaunted military brilliance suddenly seemed useless, and when the Russians put their own occupied capital to the torch, the campaign became a desperate race through the frozen landscape as troops continued to die by the thousands. Through it all, with tragic heroism, Napoleon’s disease-ravaged, freezing, starving men somehow rallied, again and again, to cries of “Vive l’Empereur!”Yet Talty’s sweeping tale takes us far beyond the doomed heroics and bloody clashes of the battlefield. The Illustrious Dead delves deep into the origins of the pathogen that finally ended the mighty emperor’s dreams of world conquest and exposes this “war plague’s” hidden role throughout history. A tale of two unstoppable forces meeting on the road to Moscow in an epic clash of killer microbe and peerless army, The Illustrious Dead is a historical whodunit in which a million lives hang in the balance.