In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    Includes essays and excerpts from the works of prominent modern thinkers such as Umberto Eco, Jacques Derrida, and Isaiah Berlin among others.

    He shows how many intellectuals have denied the existence of human nature by embracing three linked dogmas: the Blank Slate (the mind has no innate traits), the Noble Savage (people are born good and corrupted by society), and the Ghost in the Machine (each of us has a soul that makes choices free from biology). Each dogma carries a moral burden, so their defenders have engaged in desperate tactics to discredit the scientists who are now challenging them.Pinker injects calm and rationality into these debates by showing that equality, progress, responsibility, and purpose have nothing to fear from discoveries about a rich human nature. He disarms even the most menacing threats with clear thinking, common sense, and pertinent facts from science and history.Despite its popularity among intellectuals during much of the twentieth century, he argues, the doctrine of the Blank Slate may have done more harm than good. It denies our common humanity and our individual preferences, replaces hardheaded analyses of social problems with feel-good slogans, and distorts our understanding of government, violence, parenting, and the arts.Pinker shows that an acknowledgement of human nature that is grounded in science and common sense, far from being dangerous, can complement insights about the human condition made by millennia of artists and philosophers. All this is done in the style that earned his previous books many prizes and worldwide acclaim: wit, lucidity, and insight into matters great and small.

    Dickson Despommier's visionary book provides a blueprint for securing the world's food supply and at the same time solving one of the gravest environmental crises facing us today."--StingImagine a world where every town has their own local food source, grown in the safest way possible, where no drop of water or particle of light is wasted, and where a simple elevator ride can transport you to nature's grocery store - imagine the world of the vertical farm.When Columbia professor Dickson Despommier set out to solve America's food, water, and energy crises, he didn't just think big - he thought up. Despommier's stroke of genius, the vertical farm, has excited scientists, architects, and politicians around the globe. Now, in this groundbreaking book, Despommier explains how the vertical farm will have an incredible impact on changing the face of this planet for future generations.Despommier takes readers on an incredible journey inside the vertical farm, buildings filled with fruits and vegetables that will provide local food sources for entire cities.Vertical farms will allow us to:- Grow food 24 hours a day, 365 days a year- Protect crops from unpredictable and harmful weather- Re-use water collected from the indoor environment- Provide jobs for residents- Eliminate use of pesticides, fertilizers, or herbicides- Drastically reduce dependence on fossil fuels- Prevent crop loss due to shipping or storage- Stop agricultural runoffVertical farms can be built in abandoned buildings and on deserted lots, transforming our cities into urban landscapes which will provide fresh food grown and harvested just around the corner. Possibly the most important aspect of vertical farms is that they can built by nations with little or no arable land, transforming nations which are currently unable to farm into top food producers. In the tradition of the bestselling The World Without Us, The Vertical Farm is a completely original landmark work destined to become an instant classic

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Featuring two of Chomsky's most popular and enduring books in one omnibus volume, On Language contains some of the noted linguist and political critic's most informal and accessible work to date, making it an ideal introduction to his thought.In Part I, Language and Responsibility (1979), Chomsky presents a fascinating self-portrait of his political, moral, and linguistic thinking through a series of interviews with Mitsou Ronat, the noted French linguist. In Part II, Reflections on Language (1975), Chomsky explores the more general implications of the study of language and offers incisive analyses of the controversies among psychologists, philosophers, and linguists over fundamental questions of language.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    Global sea levels, as the result of rapidly melting polar ice rose by more than 300 feet in a very short period of time, causing the planet to become unstable.In Egypt, Peru, Bolivia, Lebanon and other locations we see the existence of ancient damaged but very sophisticated megalithic stone structures which we would be hard pressed to re-create today. They hint that once upon a time one or "Atlantean" civilizations indeed did exist

    The consequences of this gathering may be enormous. In this new ebook, experts Patrick J. Michaels and Paul C. Knappenberger assess the issues sure to drive the debate before, during, and after the Paris meeting.

    In Living With Darwin, Philip Kitcher stokes the flames swirling around Darwin's theory, sifting through the scientific evidence for evolution, Creation Science, and Intelligent Design, and revealing why evolution has been the object of such vehement attack. Kitcher first provides valuable perspective on the present controversy, describing the many puzzles that blocked evolution's acceptance in the early years, and explaining how scientific research eventually found the answers to these conundrums. Interestingly, Kitcher shows that many of these early questions have been resurrected in recent years by proponents of Intelligent Design. In fact, Darwin himself considered the issue of intelligent design, and amassed a mountain of evidence that effectively refuted the idea. Kitcher argues that the problem with Intelligent Design isn't that it's not science, as many critics say, but that it's dead science, raising questions long resolved by scientists. But Kitcher points out that it is also important to recognize the cost of Darwin's success--the price of life with Darwin. Darwinism has a profound effect on our understanding of our place in the universe, on our religious beliefs and aspirations. It is in truth the focal point of a larger clash between religious faith and modern science. Unless we can resolve this larger issue, the war over evolution will go on.

    Since then, deformed frogs have been turning up in lakes around the world. Written by the only journalist granted access to secret hot spots where these deformed frogs are tested, and brainstorming sessions among the researchers, this compelling, fast-paced narrative is the first to offer a complete picture of what is quite possibly a global catastrophe in the making.

    Coated in red dust, the terrain is bewilderingly empty. And yet multiple spacecraft are circling Mars, sweeping over Terra Sabaea, Syrtis Major, the dunes of Elysium, and Mare Sirenum—on the brink, perhaps, of a staggering find, one that would inspire humankind as much as any discovery in the history of modern science.In this beautifully observed, deeply personal book, Georgetown scientist Sarah Stewart Johnson tells the story of how she and other researchers have scoured Mars for signs of life, transforming the planet from a distant point of light into a world of its own.Johnson’s fascination with Mars began as a child in Kentucky, turning over rocks with her father and looking at planets in the night sky. She now conducts fieldwork in some of Earth’s most hostile environments, such as the Dry Valleys of Antarctica and the salt flats of Western Australia, developing methods for detecting life on other worlds. Here, with poetic precision, she interlaces her own personal journey—as a female scientist and a mother—with tales of other seekers, from Percival Lowell, who was convinced that a utopian society existed on Mars, to Audouin Dollfus, who tried to carry out astronomical observations from a stratospheric balloon. In the process, she shows how the story of Mars is also a story about Earth: This other world has been our mirror, our foil, a telltale reflection of our own anxieties and yearnings.Empathetic and evocative, The Sirens of Mars offers an unlikely natural history of a place where no human has ever set foot, while providing a vivid portrait of our quest to defy our isolation in the cosmos.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    The calls to ban it were more or less instant.Re:cyclists is the tale of what happened next, of how we have spent two centuries wheeling our way about town and country on bikes--or on two-wheeled things that vaguely resembled what we now call bikes. Michael Hutchinson picks his way through those 200 years, discovering how cycling became a kinky vaudeville act for Parisians, how it became an American business empire, and how it went on to find a unique home in the British Isles. He considers the penny-farthing riders exploring the abandoned and lonely coaching roads during the railway era, and the Victorian high-society cyclists of the 1890s bicycle craze--a time when no aristocratic house party was without bicycles and when the Prince of Wales used to give himself an illicit thrill on a weekday afternoon by watching the women's riding-school in the Royal Albert Hall.Re:cyclists looks at how cycling became the sport, the pastime and the social life of millions of ordinary people, how it grew and how it suffered through the 1960s and '70s, and how at the dawn of the twenty-first century it rose again, much changed but still ultimately just someone careering along on two wheels.

    But it was not reels of wool or bales of cotton that awaited him, but plants and seeds…Over the next forty years, Bartram would send hundreds of American species to England, where Collinson was one of a handful of men who would foster a national obsession and change the gardens of Britain forever, introducing lustrous evergreens, fiery autumn foliage and colourful shrubs. They were men of wealth and taste but also of knowledge and experience like Philip Miller, author of the bestselling Gardeners Dictionary, and the Swede Carl Linnaeus, whose standardised botanical nomenclature popularised botany as a genteel pastime for the middle-classes; and the botanist-adventurer Joseph Banks and his colleague Daniel Solander who both explored the strange flora of Tahiti and Australia on the greatest voyage of discovery of modern times, Captain Cook’s Endeavour.This is the story of these men – friends, rivals, enemies, united by a passion for plants – whose correspondence, collaborations and squabbles make for a riveting human tale which is set against the backdrop of the emerging empire, the uncharted world beyond and London as the capital of science. From the scent of the exotic blooms in Tahiti and Botany Bay to the gardens at Chelsea and Kew, and from the sounds and colours of the streets of the City to the staggering vistas of the Appalachian mountains, The Brother Gardeners tells the story of how Britain became a nation of gardeners.