Charting the most cutting-edge scientific breakthroughs, and marshalling his decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood and energy levels, regulate hormones, prevent cancer, Alzheimer's and diabetes, slow the effects of aging, and increase longevity. He also provides actionable steps towards getting a better night's sleep every night.

    In fact, your body is actually endowed with many self-defense measures to hold on to fat. For example, fat can use stem cells to regenerate; increase our appetite if it feels threatened; and use bacteria, genetics, and viruses to expand itself. The secret to losing twenty pounds? You have to work with your fat, not against it. Tara explains how your fat influences your appetite and willpower, how it defends itself when attacked, and why it grows back so quickly. The Secret Life of Fat brings cutting-edge research together with historical perspectives to reveal fat’s true identity: an endocrine organ that, in the right amount, is critical to our health. Fat triggers puberty, enables our reproductive and immune systems, and even affects brain size.Although we spend $60 billion annually fighting fat, our efforts are often misinformed and misdirected. Tara expertly illustrates the complex role that genetics, hormones, diet, exercise, and history play in our weight, and The Secret Life of Fat sets you on the path to beat the bulge once and for all.

    A great vocabulary can enhance your speaking, writing, and even thinking skills. This course will boost your vocabulary, whether you want to enhance your personal lexicon, write or speak more articulately in professional settings, or advance your knowledge of the English language. For anyone who has ever grasped for the perfect word at a particular moment, this course provides a research-based and enjoyable method for improving your vocabulary. Building a Better Vocabulary offers an intriguing look at the nuts and bolts of English, teaches you the etymology and morphology - or the history and structure - of words, and delves into the cognitive science behind committing new words to long-term memory. By the end of the 36 enjoyable lectures, you will have a practical framework for continuing to build your vocabulary by discovering new words and fully mastering the nuances of familiar ones. If you are an avid reader, you may have previously encountered some of the words in this course. But even the most voracious reader will be surprised and delighted by these eye-opening lectures, which delve into the building blocks of the English language and reveal intriguing new nuances to words you thought you knew well. These lectures will kindle a passion for the process by which words are created and for the beauty of the words you read, speak, and hear every day.

    For instance, it's not hard to envision a day when websites such as Facebook or Google Maps introduce a feature that allows real-time tracking of anyone you want, based on face-recognition software and ubiquitous live video feeds.Does this scenario sound like an unconstitutional invasion of privacy? These 24 eye-opening lectures immerse you in the Constitution, the courts, and the post-9/11 Internet era that the designers of our legal system could scarcely have imagined. Professor Rosen explains the most pressing legal issues of the modern day and asks how the framers of the U.S. Constitution and the Bill of Rights would have reacted to aspects of the modern life such as full-body scans, cell phone surveillance, and privacy in cloud servers.Called "the nation's most widely read and influential legal commentator" by the Los Angeles Times, Professor Rosen is renowned for his ability to bring legal issues alive - to put real faces and human drama behind the technical issues that cloud many legal discussions. Here he asks how you would decide particular cases about liberty and privacy. You'll come away with a more informed opinion about whether modern life gives even the most innocent among us reason to worry.

    The answer to this age-old riddle is universally relevant to our lives. The implications of our views on it can affect everything from small choices we make every day to our perspective on criminal justice and capital punishment. From the Stoics to Boethius, from Kant to Hume, from Sartre to contemporary philosophers, great minds have puzzled over this debate for centuries.Now you can learn the intriguing details of this fundamental philosophical question with Great Philosophical Debates: Free Will and Determinism, 24 fascinating lectures by Shaun Nichols, award-winning Professor of Philosophy and Cognitive Science at the University of Arizona."The Great Courses.com

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    Relativity and quantum physics touch the very basis of physical reality, altering our commonsense notions of space and time, cause and effect. Both have reputations for complexity. But the basic ideas behind relativity and quantum physics are, in fact, simple and comprehensible by anyone. As Professor Wolfson points out, the essence of relativity can be summed up in a single sentence: The laws of physics are the same for all observers in uniform motion. The same goes for quantum theory, which is based on the principle that the "stuff " of the universe-matter and energy-is not infinitely divisible but comes in discrete chunks called "quanta." Profound ... Beautiful ... Relevant Why should you care about these landmark theories? Because relativity and quantum physics are not only profound and beautiful ideas in their own right, they are also the gateway to understanding many of the latest science stories in the media. These are the stories about time travel, string theory, black holes, space telescopes, particle accelerators, and other cutting-edge developments. Consider these ideas: Although Einstein's theory of general relativity dates from 1914, it has not been possible to test certain predictions until recently. The Hubble Space Telescope is providing some of the most striking confirmations of the theory, including certain evidence for the existence of black holes, objects that warp space and time so that not even light can escape. Also, the expansion of the universe predicted by the theory of general relativity is now a known rate. General relativity also predicts an even weirder phenomenon called "wormholes" that offer shortcuts to remote reaches of time and space. According to Einstein's theory of special relativity, two twins would age at different rates if one left on a high-speed journey to a distant star and then returned. This experiment has actually been done, not with twins, but with an atomic clock flown around the world. Another fascinating experiment confirming that time slows as speed increases comes from measuring muons at the top and bottom of mountains. A seemingly absurd consequence of quantum mechanics, called "quantum tunneling," makes it possible for objects to materialize through impenetrable barriers. Quantum tunneling happens all the time on the subatomic scale and plays an important role in electronic devices and the nuclear processes that keep the sun shining. Some predictions about the expansion of the universe were so odd that Einstein himself tried to rewrite the mathematics in order to eliminate them. When Hubble discovered the expansion of the universe, Einstein called the revisions the biggest mistake he had ever made. An intriguing thought experiment called "Schrödinger's cat" suggests that a cat in an enclosed box is simultaneously alive and dead under experimental conditions involving quantum phenomena. From Aristotle to the Theory of Everything Professor Wolfson begins with a brief overview of theories of physical reality starting with Aristotle and culminating in Newtonian or "classical" physics. Then he outlines the logic that led to Einstein's theory of special relativity, and the simple yet far-reaching insight on which it rests. With that insight in mind, you move on to consider Einstein's theory of general relativity and its interpretation of gravitation in terms of the curvature of space and time. Professor Wolfson then shows how inquiry into matter at the atomic and subatomic scales led to quandaries that are resolved-or at least clarified-by quantum mechanics, a vision of physical reality so at odds with our experience that it nearly defies language. Bringing relativity and quantum mechanics into the same picture leads to hypotheses about the origin, development, and possible futures of the entire universe, and the possibility that physics can produce a "theory of everything" to account for all aspects of the physical world. Fascinating Incidents and Ideas Along the way, you'll explore these fascinating incidents and ideas: In the 1880s, Albert Michelson and Edward Morley conducted an experiment to determine the motion of the Earth relative to the ether, which was a supposedly imponderable substance pervading all of space. You'll learn about their experiment, its shocking result, and the resulting theoretical crisis. In 1905, a young Swiss patent clerk named Albert Einstein resolved the crisis by discarding the ether concept and asserting the principle of relativity-that the laws of physics are the same for all observers in uniform motion. Relativity implies that the time order of events can be different in different reference frames. Does this wreak havoc with cause and effect? And why does Einstein assert that nothing can go faster than light? Shortly after publishing his 1905 paper on special relativity, Einstein realized that his theory required a fundamental equivalence between mass and energy, which he expressed in the equation E=mc2. Among other things, this famous formula means that the energy contained in a single raisin could power a large city for a whole day. Historically, the path to general relativity followed Einstein's attempt to incorporate gravity into relativity theory, which led to his understanding of gravity not as a force, but as a local manifestation of geometry in curved spacetime. Quantum theory places severe limits on our ability to observe nature at the atomic scale because it implies that the act of observation necessarily disturbs the thing that is being observed. The result is Werner Heisenberg's famous "uncertainty principle." Are quarks, the particles that make up protons and neutrons, the truly elementary particles? What are the three fundamental forces that physicists identify as holding particles together? Could they be manifestations of a single, universal force? A Teaching Legend On his own Middlebury College campus, Professor Wolfson is a teaching legend with an infectious enthusiasm for his subject and a knack for conveying difficult concepts in a way that fosters true understanding. He is the author of an introductory text on physics, a contributor to the esteemed publication Scientific American, and a specialist in interpreting science for the nonspecialist. In this course, Professor Wolfson uses extensive illustrations and diagrams to help bring to life the theories and concepts that he discusses. Thus we highly recommend our DVD version, although Professor Wolfson is mindful of our audio students and carefully describes visual materials throughout his lectures. Professor Richard Wolfson on the Second Edition of Einstein's Relativity: "The first version of this course was produced in 1995. In this new version, I have chosen to spend more time on the philosophical interpretation of quantum physics, and on recent experiments relevant to that interpretation. I have also added a final lecture on the theory of everything and its possible implementation through string theory. The graphic presentations for the DVD version have also been extensively revised and enhanced. But the goal remains the same: to present the key ideas of modern physics in a way that makes them clear to the interested layperson."

    In The Joy of Sweat, Sarah Everts delves into its role in the body—and in human history.Why is sweat salty? Why do we sweat when stressed? Why do some people produce colorful sweat? And should we worry about Big Brother tracking the hundreds of molecules that leak out in our sweat—not just the stinky ones or alleged pheromones—but the ones that reveal secrets about our health and vices?Everts’s entertaining investigation takes readers around the world—from Moscow, where she participates in a dating event in which people sniff sweat in search of love, to New Jersey, where companies hire trained armpit sniffers to assess the efficacy of their anti-sweat products. In Finland, Everts explores the delights of the legendary smoke sauna and the purported health benefits of good sweat, while in the Netherlands she slips into the sauna theater scene, replete with costumes, special effects, and towel dancing.Along the way, Everts traces humanity’s long quest to control sweat, culminating in the multi-billion-dollar industry for deodorants and antiperspirants. And she shows that while sweating can be annoying, our sophisticated temperature control strategy is one of humanity’s most powerful biological traits. Deeply researched and written with great zest, The Joy of Sweat is a fresh take on a gross but engrossing fact of human life.

    But now, with revolutionary medical advances, death has become just another serious complication. As a young medical student, Dr. David Casarett was inspired by the story of a two-year-old girl named Michelle Funk. Michelle fell into a creek and was underwater for over an hour. When she was found she wasn’t breathing, and her pupils were fixed and dilated. That drowning should have been fatal. But after three hours of persistent work, a team of doctors and nurses was able to bring her back. It was a miracle. If Michelle could come back after three hours of being dead, what about twelve hours? Or twenty-four? What would it take to revive someone who had been frozen for one thousand years? And what does blurring the line between “life” and “death” mean for society? In Shocked, Casarett chronicles his exploration of the cutting edge of resuscitation and reveals just how far science has come. He begins in the eighteenth century, when early attempts at resuscitation involved public displays of barrel rolling, horseback riding (sort of), and blowing smoke up the patient’s various orifices. He then takes us inside a sophisticated cryonics facility in the Arizona desert, a darkroom full of hibernating lemurs in North Carolina, and a laboratory that puts mice into a state of suspended animation. The result is a spectacular tour of the bizarre world of doctors, engineers, animal biologists, and cryogenics enthusiasts trying to bring the recently dead back to life. Fascinating, thought-provoking, and (believe it or not) funny, Shocked is perfect for those looking for a prequel—and a sequel—to Mary Roach’s Stiff, or for anyone who likes to ponder the ultimate questions of life and death.

      From bizarre dreams and hallucinations to schizophrenia and multiple personalities, the human brain is responsible for a diverse spectrum of strange thoughts and behaviors. When observed from the outside, these phenomena are often written off as being just “crazy,” but what if they were actually planned and logical?  NeuroLogic explores the brain’s internal system of reasoning, from its unconscious depths to conscious decision making, and illuminates how it explains our most outlandish as well as our most stereotyped behaviors. From sleepwalking murderers, contagious yawning, and the brains of sports fans to false memories, subliminal messages, and the secret of ticklishness, Dr. Eliezer Sternberg shows that there are patterns to the way the brain interprets the world—–patterns that fit the brain’s unique logic. Unraveling these patterns and the various ways they can be disturbed will not only alter our view of mental illness and supernatural experience, but will also shed light on the hidden parts of ourselves.  (With black-and-white illustrations throughout.)

    

    In 'Bad Science', Ben Goldacre hilariously exposed the tricks that quacks and journalists use to distort science. In 'Bad Pharma', he put the $600 billion global pharmaceutical industry under the microscope. Now the pick of the journalism by one of our wittiest, most indignant and most fearless commentators on the worlds of medicine and science is collected in one volume.

    By turns humorous and moving, Tales from Both Sides of the Brain interweaves Gazzaniga’s scientific achievements with his reflections on the challenges and thrills of working as a scientist.

    Late Middle Ages-Rebirth, Waning, Calamity? 2. Philip the Fair versus Boniface VIII 3. Fall of the Templars and the Avignon Papacy 4. The Great Papal Schism 5. The Hundred Years War, Part 1 6. The Hundred Years War, Part 2 7. The Black Death, Part 1 8. The Black Death, Part 2 9. Revolt in Town and Country 10. William Ockham 11. John Wycliffe and the Lollards 12. Jan Hus and the Hussite Rebellion 13. Witchcraft 14. Christine de Pizan and Catherine of Siena 15. Gunpowder 16. The Printing Press 17. Renaissance Humanism, Part 1 18. Renaissance Humanism, Part 2 19. The Fall of the Byzantine Empire 20. Ferdinand and Isabella 21. The Spanish Inquisition 22. The Age of Exploration 23. Columbus and the Columbian Exchange 24. When Did the Middle Ages End? Late Middle Ages (24 lectures, 30 minutes/lecture)Course No. 8296 Taught by Philip DaileaderThe College of William and MaryPh.D., Harvard University

    A prize-winning, successful novelist in her 30s, McCracken was happy to be an itinerant writer and self-proclaimed spinster. But suddenly she fell in love, got married, and two years ago was living in a remote part of France, working on her novel, and waiting for the birth of her first child.This book is about what happened next. In her ninth month of pregnancy, she learned that her baby boy had died. How do you deal with and recover from this kind of loss? Of course you don't--but you go on. And if you have ever experienced loss or love someone who has, the company of this remarkable book will help you go on.