But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    

    But what if our actions are driven not by our conscious values and beliefs but by hidden motivations we’re not even aware of?The “hidden brain” is Shankar Vedantam’s shorthand for a host of brain functions, emotional responses, and cognitive processes that happen outside our conscious awareness but have a decisive effect on how we behave. The hidden brain has its finger on the scale when we make all our most complex and important decisions: It decides whom we fall in love with, whether we should convict someone of murder, and which way to run when someone yells “Fire!” It explains why we can become riveted by the story of a single puppy adrift on the ocean but are quickly bored by a story of genocide. The hidden brain can also be deliberately manipulated to convince people to vote against their own interests, or even become suicide terrorists. But the most disturbing thing is that it does all this without our knowing.Shankar Vedantam, author of The Washington Post’s popular “Department of Human Behavior” column, takes us on a tour of this phenomenon and explores its consequences. Using original reporting that combines the latest scientific research with compulsively readable narratives that take readers from the American campaign trail to terrorist indoctrination camps, from the World Trade Center on 9/11 to, yes, a puppy adrift on the Pacific Ocean, Vedantam illuminates the dark recesses of our minds while making an original argument about how we can compensate for our blind spots and what happens when we don’t.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    This amazing organ has unique powers to make predictions about the future, form relationships with other people, adapt to rapidly changing circumstances, and so much more. We all have a basic conception of how our brains function, but when did you last dive into the fascinating world of neuroscience to truly understand the inner workings of your mind? For decades, the field of neuroscience has been in a near-constant state of disruptive transformation, as we continually learn more about our incredible brains. Thanks to rapid advances in technology and in our understanding of the brain, today’s neuroscience research goes far beyond trying to understand how the brain works, and into the search for proven ways to optimize brain performance. In Your Best Brain, Professor John J. Medina - an award-winning scientist, New York Times best-selling author, and leading advocate for brain research - delivers 24 exciting lectures that probe the origins of consciousness, memory, emotion, attention, intelligence, and beyond. He focuses on five key areas of study in neuroscience: the brain’s physical structure and function, and how it enabled us to become the planet’s apex predator; the ways in which the brain processes information, and how that relates to intelligence; the intricacies of emotions and socialization, and how empathy is a vital survival mechanism; how our brains develop and change throughout our lifetimes; and how we can best use and expand our cerebral processing performance. After gaining a thorough understanding of the science behind your best brain, you’ll learn scientifically proven methods for improving your memory, boosting your creativity, and keeping your mind sharp for years to come.

    But the Black Death was arguably the most significant event in Western history, profoundly affecting every aspect of human life, from the economic and social to the political, religious, and cultural. In its wake the plague left a world that was utterly changed, forever altering the traditional structure of European societies and forcing a rethinking of every single system of Western civilization: food production and trade, the church, political institutions, law, art, and more. In large measure, by the profundity of the changes it brought, the Black Death produced the modern world we live in today.While the story of the Black Death is one of destruction and loss, its breathtaking scope and effects make it one of the most compelling and deeply intriguing episodes in human history. Understanding the remarkable unfolding of the plague and its aftermath provides a highly revealing window not only on the medieval world but also on the forces that brought about the Renaissance, the Protestant Reformation, and modernity itself.Speaking to the full magnitude of this world-changing historical moment, The Black Death: The World's Most Devastating Plague, taught by celebrated medievalist Dorsey Armstrong of Purdue University, takes you on an unforgettable excursion into the time period of the plague, its full human repercussions, and its transformative effects on European civilization. In 24 richly absorbing lectures, you'll follow the path of the epidemic in its complete trajectory across medieval Europe. Majestic in scope and remarkable in detail, this course goes to the heart of one of Western history's most catalytic and galvanizing moments, the effects of which gave us the modern world.

    And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

    While studying brain scans of several family members, he discovered that one perfectly matched a pattern he d found in the brains of serial killers. This meant one of two things: Either his family s scans had been mixed up with those of felons or someone in his family was a psychopath.Even more disturbing: The scan in question was his own.This is Fallon s account of coming to grips with this discovery and its implications. How could he, a happy family man who had never been prone to violence, be a psychopath? How much did his biology influence his behavior?Fallon shares his journey to answer these questions and the discoveries that ultimately led to his conclusion: Despite everything science can teach, humans are even more complex than we can imagine."

    Too bad. Because medicine isn't an industry, it's practically witchcraft. Despite the growth of big pharma, HMOs, and hospital chains, medicine remains the isolated work of individual doctors—and the system is going broke fast.So why is Andy Kessler—the man who told you outrageous stories of Wall Street analysts gone bad in Wall Street Meat and tales from inside a hedge fund in Running Money—poking around medicine for the next big wave of technology?It's because he smells change coming. Heart attacks, strokes, and cancer are a huge chunk of medical spending, yet there's surprisingly little effort to detect disease before it's life threatening. How lame is that—especially since the technology exists today to create computer-generated maps of your heart and colon?Because it's too expensive—for now. But Silicon Valley has turned computing, telecom, finance, music, and media upside down by taking expensive new technologies and making them ridiculously cheap. So why not the $1.8 trillion health care business, where the easiest way to save money is to stop folks from getting sick in the first place?Join Kessler's bizarre search for the next big breakthrough as he tries to keep from passing out while following cardiologists around, cracks jokes while reading mammograms, and watches twitching mice get injected with radioactive probes. Looking for a breakthrough, Kessler even selflessly pokes, scans, and prods himself.CT scans of your heart will identify problems before you have a heart attack or stroke; a nanochip will search your blood for cancer cells--five years before they grow uncontrollably and kill you; and baby boomers can breathe a little easier because it's all starting to happen now.Your doctor can't be certain what's going on inside your body, but technology will. Embedding the knowledge of doctors in silicon will bring a breakout technology to health care, and we will soon see an end of medicine as we know it.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    The alimentary canal is classic Mary Roach terrain: the questions explored in Gulp are as taboo, in their way, as the cadavers in Stiff and every bit as surreal as the universe of zero gravity explored in Packing for Mars. Why is crunchy food so appealing? Why is it so hard to find words for flavors and smells? Why doesn’t the stomach digest itself? How much can you eat before your stomach bursts? Can constipation kill you? Did it kill Elvis? In Gulp we meet scientists who tackle the questions no one else thinks of—or has the courage to ask. We go on location to a pet-food taste-test lab, a fecal transplant, and into a live stomach to observe the fate of a meal. With Roach at our side, we travel the world, meeting murderers and mad scientists, Eskimos and exorcists (who have occasionally administered holy water rectally), rabbis and terrorists—who, it turns out, for practical reasons do not conceal bombs in their digestive tracts.Like all of Roach’s books, Gulp is as much about human beings as it is about human bodies.

    Jason Fung returns with an eye-opening biography of cancer in which he offers a radical new paradigm for understanding cancer—and issues a call to action for reducing risk moving forward. Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline . . . but the “War on Cancer” has hardly been won.In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease—what it is, how it manifests, and why it is so challenging to treat. In this rousing narrative, Dr. Fung identifies the medical community’s many missteps in cancer research—in particular, its focus on genetics, or what he terms the “seed” of cancer, at the expense of examining the “soil,” or the conditions under which cancer flourishes. Dr. Fung—whose groundbreaking work in the treatment of obesity and diabetes has won him international acclaim—suggests that the primary disease pathway of cancer is caused by the dysregulation of insulin. In fact, obesity and type 2 diabetes significantly increase an individual’s risk of cancer.In this accessible read, Dr. Fung provides a new paradigm for dealing with cancer, with recommendations for what we can do to create a hostile soil for this dangerous seed. One such strategy is intermittent fasting, which reduces blood glucose, lowering insulin levels. Another, eliminating intake of insulin-stimulating foods, such as sugar and refined carbohydrates.For hundreds of years, cancer has been portrayed as a foreign invader we’ve been powerless to stop. By reshaping our view of cancer as an internal uprising of our own healthy cells, we can begin to take back control. The seed of cancer may exist in all of us, but the power to change the soil is in our hands.

    In fact, a plethora of parasites affect our behavior in ways we have barely begun to understand.  In this mind-bending book, McAuliffe reveals the eons-old war between parasites and other creatures that is playing out in our very own bodies. And more surprising still, she uncovers the decisive role that parasites may have played in the rise and demise of entire civilizations. Our obsession with cleanliness and our experience of disgust are both evolutionary tools for avoiding infection, but they evolved differently for different populations. Political, social, and religious differences among societies may be caused, in part, by the different parasites that prey on us. In the tradition of Jared Diamond’s Guns, Germs, and Steel and Neil Shubin’s Your Inner Fish, This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human.

    Diligently researching how to restore his quality of life, she discovered Vet-Stem, a service that provides cutting-edge regeneration therapy for pets, using stem cells harvested from animals' own tissue. Just hours after receiving IV and intra-joint injections, Sam began aging backward--which left Julia wondering why this simple, effective treatment was not available for humans.            Julia suffered from chronic inflammatory bowel disease, and after witnessing Sam's astonishing recovery, she set out on a curious quest: to be treated like a dog by a doctor as competent as her vet! After a four-year wait, Julia became the first American to be successfully cured of a perirectal fistula with stem cells derived from her own fat. With this amazing true story of how a pack of shelter dogs she rescued from death row came to save her life, Julia hopes to inspire and inform readers about exciting healthcare options available to them and their cherished animal companions.

    It lasted 3,000 years, longer than any other on the planet. Its Great Pyramid of Cheops was the tallest building in the world until well into the 19th century and remains the only Ancient Wonder still standing. And it was the most technologically advanced of the ancient civilizations, with the medical knowledge that made Egyptian physicians the most famous in the world.Yet even after deciphering its hieroglyphs, and marveling at its scarabs, mummies, obelisks, and sphinxes, Egyptian civilization remains one of history's most mysterious, as "other" as it is extraordinary. This chronological survey presents the complete history of ancient Egypt's three great Kingdoms: the Old Kingdom, when the pyramids were built and Egypt became a nation under the supreme rule of the pharaoh and the rules of Egyptian art were established; the Middle Kingdom, when Egypt was a nation fighting to restore its greatness; and the New Kingdom, when all the names we know today-Hatshepsut, Tutankhamen, Ramses the Great, Cleopatra, and others-first appeared.Listening Length: 24 hours and 25 minutes