In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

     Launched in 1936 by Princess Marina, the Duchess of Kent, HMS Sheffield was the third of the Royal Navy’s ten Town-class cruisers. She marked a number of firsts: the first ship to be named for Sheffield, the first to have stainless steel fixtures instead of brass, and the first to carry operational RDF (Radio Direction Finding) equipment. Old Shiny, as she became affectionately known, was manufactured to the high standards of peacetime. Even hitting a mine was unable to render her inactive for long. Her crew simply manufactured a wooden patch, and saw her safely home. Achieving twelve honours over thirty years’ service, Old Shiny notably exchanged salvoes with the Bismarck, engaged Admiral Hipper and Lützow, and helped sink Scharnhorst. A more unusual deployment came in 1956, as HMS Sheffield was one of the ships loaned by the Admiralty for the Technicolor epic The Battle of the River Plate! Drawn from the experiences of the men who lived, fought and served on board, in HMS Sheffield Ronald Bassett paints an evocative and highly personal portrait of Old Shiny, and shows how she was more than just a warship. Praise for Ronald Bassett ‘One of the most impressive things I found about the book was that you got a real feel for the time and place. Scenes set in India or England felt different and I think that's a great achievement.’ – Library Thing ‘vividly described … the voyage as seen through the sleep-robbed eyes of matelots and officers alike’ – Daily Telegraph ‘A catalogue of horror’ – Eastern Daily Press ‘There is a degree of authenticity that makes the blood run cold’ – Cambridge News ‘Fast, vigorous action’ – Sheffield Morning Telegraph ‘Graphic tale of slave and convict ships… not for tender stomachs’ – Books and Bookmen Ronald Bassett (1924-1996) was born in Chelsea. During the Munich crisis, at age fourteen, he falsified enlistment papers to become a Rifleman of the King’s Royal Rifle Corps (60th Rifles). Following active service, he was exposed and discharged. In his records, his colonel noted, ‘A good soldier. I am sorry to lose him.’ Undismayed, he immediately entered the Royal Navy, in which he remained for fourteen years, serving in the Arctic, North Atlantic, Mediterranean, the Far East and, later, Korea. He died in Surrey.

    He paints vivid portraits of psychiatry's leading historical figures and pulls no punches in assessing their roles in advancing or sidetracking our understanding of the origins of mental illness.Shorter also identifies the scientific and cultural factors that shaped the development of psychiatry. He reveals the forces behind the unparralleled sophisitication of psychiatry in Germany during the eighteenth and nineteenth centuries as well as the emergence of the United States as the world capital of psychoanalysis. This engagingly written, thoroughly researched, and fiercely partisan account is compelling reading for anyone with a personal, intellectual, or professional interest in psychiatry.Description from Goodreads User:The history of madness and its treatment is a fascinating one. At one time, the mentally ill were diagnosed as demonically possessed; later, when mental illness became the province of psychoanalysts, those conditions that are actually physical in nature, such as schizophrenia or manic depression, went insufficiently treated, their sufferers consigned to asylums. In his book, A History of Psychiatry, Edward Shorter, a medical historian at the University of Toronto, presents a concise chronology of mental illness and its treatment. Shorter favors a biological understanding of these disorders, concentrating on medical approaches to helping the seriously mentally ill.

    All of the mentioned are just puppets on an invisible string doing the biddings of a few unseen puppeteers. Yes, that’s right. A few elite and undisclosed organizations send our children off to war, restrict the growth of the middle class, and limit educational opportunities for American citizens. The sad truth is this is nothing new. Thomas Jefferson and Benjamin Franklin warned of the dangers and destructive power of these elites if left unchecked. These few unchosen were able, and continue, to use the Federal Reserve Banking System, universities, and war to create economic recessions and depressions that provide unnoticed benefits to a select group of social manipulators. In this stunning new book, Mark Mullen takes us on an intellectual journey through the world of secret partnerships created by unfamiliar ideologues designed to acquire most of the nation’s wealth and power. In Who Controls America, Mullen shines a light on those few elites who place greed, power, and profits above the interests of the American citizen and the pursuit of the American Dream.

    With swashbuckling wit and fierce honesty, she dishes on herself and her colleagues as they try to prod reluctant governments to fund HIV prevention for the people who need it most—drug injectors, gay men, sex workers, and johns.Pisani chats with flamboyant Indonesian transsexuals about their boob jobs and watches Chinese streetwalkers turn away clients because their SUVs aren't nice enough. With verve and clarity, she shows the general reader how her profession really works; how easy it is to draw wrong conclusions from "objective" data; and, shockingly, how much money is spent so very badly. "Exhibit A": the 45 billion taxpayer dollars the Bush administration is committing to international AIDS programs.

    But the war produced the largest biological crisis of the nineteenth century, and as historian Jim Downs reveals in this groundbreaking volume, it had deadly consequences for hundreds of thousands of freed people.In Sick from Freedom, Downs recovers the untold story of one of the bitterest ironies in American history--that the emancipation of the slaves, seen as one of the great turning points in U.S. history, had devastating consequences for innumerable freed people. Drawing on massive new research into the records of the Medical Division of the Freedmen's Bureau-a nascent national health system that cared for more than one million freed slaves-he shows how the collapse of the plantation economy released a plague of lethal diseases. With emancipation, African Americans seized the chance to move, migrating as never before. But in their journey to freedom, they also encountered yellow fever, smallpox, cholera, dysentery, malnutrition, and exposure. To address this crisis, the Medical Division hired more than 120 physicians, establishing some forty underfinanced and understaffed hospitals scattered throughout the South, largely in response to medical emergencies. Downs shows that the goal of the Medical Division was to promote a healthy workforce, an aim which often excluded a wide range of freedpeople, including women, the elderly, the physically disabled, and children. Downs concludes by tracing how the Reconstruction policy was then implemented in the American West, where it was disastrously applied to Native Americans.The widespread medical calamity sparked by emancipation is an overlooked episode of the Civil War and its aftermath, poignantly revealed in Sick from Freedom.

    Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.

     Were it not for the heroic efforts of the Q-ships, the naval war could have proven disastrous for the allies. Between 1914 and 1918, nearly 200 commercial vessels were transformed into armed decoy ships that lured U-boats into attacking them at close range before responding with their own deadly fire at the very last moment. From tramp steamers to sailing ships, from fishing boats to tugs, every type of ship was used in this great act of deception. The demands on the crews of these ships were immense – requiring supreme bravery, exceptional patience, a high degree of cunning and excellent seamanship. In this book, E. Keble Chatterton takes us through the story of these ships in an entertaining narrative, highlighting one of the lesser known aspects of World War One. Writing with narrative flair and a passion for the subject, Chatterton places the reader in the middle of the tense war for the Atlantic. Edward Keble Chatterton (1878-1944) was a sailor and prolific writer from Sheffield. His voyages across the English Channel, to the Netherlands, around the Mediterranean and through the French canals led to many articles and books. Joining the R.N.V.R. at the outbreak of WWI he commanded a motor launch flotilla, leaving the service in 1919 as a Lieutenant Commander. Between the wars his output included works about model ships, juvenile novels, and narrative histories of naval events; from 1939, his writing focused upon WWII.

    Examining the cultural politics of public health and Chinese immigration in San Francisco, this book looks at the history of racial formation in the U.S. by focusing on the development of public health bureaucracies. Nayan Shah notes how the production of Chinese difference and white, heterosexual norms in public health policy affected social lives, politics, and cultural expression. Public health authorities depicted Chinese immigrants as filthy and diseased, as the carriers of such incurable afflictions as smallpox, syphilis, and bubonic plague. This resulted in the vociferous enforcement of sanitary regulations on the Chinese community. But the authorities did more than demon-ize the Chinese; they also marshaled civic resources that promoted sewer construction, vaccination programs, and public health management. Shah shows how Chinese Americans responded to health regulations and allegations with persuasive political speeches, lawsuits, boycotts, violent protests, and poems. Chinese American activists drew upon public health strategies in their advocacy for health services and public housing. Adroitly employing discourses of race and health, these activists argued that Chinese Americans were worthy and deserving of sharing in the resources of American society.

    Facing such horrors, many patients ran with open arms to burgeoning practices that promised new ways to cure their ills. Hydropaths offered cures using “healing waters” and tight wet-sheet wraps. Phineas Parkhurst Quimby experimented with magnets and tried to replace “bad,” diseased thoughts with “good,” healthy thoughts, while Daniel David Palmer reportedly restored a man’s hearing by knocking on his vertebrae. Lorenzo and Lydia Fowler used their fingers to “read” their clients’ heads, claiming that the topography of one’s skull could reveal the intricacies of one’s character. Lydia Pinkham packaged her Vegetable Compound and made a famous family business from the homemade cure-all. And Samuel Thomson, rejecting traditional medicine, introduced a range of herbal remedies for a vast array of woes, supplemented by the curative powers of poetry.   Bizarre as these methods may seem, many are the precursors of today’s notions of healthy living. We have the nineteenth-century practice of “medical gymnastics” to thank for today’s emphasis on regular exercise, and hydropathy’s various water cures for the notion of regular bathing and the mantra to drink “eight glasses of water a day.” And much of the philosophy of health introduced by these alternative methods is reflected in today’s patient-centered care and holistic medicine, which takes account of the body and spirit. Moreover, these entrepreneurial alternative healers paved the way for women in medicine. Shunned by the traditionalists and eager for converts, many of the masters of these new fields embraced the training of women in their methods. Some women, like Pinkham, were able to break through the barriers to women working to become medical entrepreneurs themselves. In fact, next to teaching, medicine attracted more women than any other profession in the nineteenth century, the majority of them in “irregular” health systems.   These eccentric ideas didn’t make it into modern medicine without a fight, of course. As these new healing methods grew in popularity, traditional doctors often viciously attacked them with cries of “quackery” and pressed legal authorities to arrest, fine, and jail irregulars for endangering public safety. Nonetheless, these alternative movements attracted widespread support—from everyday Americans and the famous alike, including Mark Twain, Louisa May Alcott, and General Ulysses S. Grant—with their messages of hope, self-help, and personal empowerment.   Though many of these medical fads faded, and most of their claims of magical cures were discredited by advances in medical science, a surprising number of the theories and ideas behind the quackery are staples in today’s health industry. Janik tells the colorful stories of these “quacks,” whose oftentimes genuine wish to heal helped shape and influence modern medicine.

    Includes timelines, boxed features on significant medical breakthroughs, fascinating case histories, anecdotes and medical curiosities. Contains 150 color photographs.

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.