From these basics, they sought to understand the essential ingredients of the world. Those who could see further, those who understood that the four were just the beginning, were the last sorcerers ? and the world's first chemists.What we now call chemistry began in the fiery cauldrons of mystics and sorcerers seeking not to make a better world through science, but rather to make themselves richer through magic formulas and con games. But among these early magicians, frauds, and con artists were a few far-seeing alchemists who, through rigorous experimentation, transformed mysticism into science.By the 18th century the building blocks of nature, the elements of which all matter is composed, were on the verge of being discovery. Initially, it was not easy to determine whether a substance really was an element. Was water just water, plain and simple? Or could it be the sum of other (unknown and maybe unknowable) parts? And if water was made up of other substances, how could it be broken down into discreet, fundamental, and measurable components?Scientific historians generally credit the great 18th century French chemist Antoine Lavoisier with addressing these fundamental questions and ultimately modernizing the field of chemistry. Through his meticulous and precise work this chaotic new field of scientific inquiry was given order. Exacting by nature, Lavoisier painstakingly set about performing experiments that would provide lasting and verifiable proofs of various chemical theories. Unfortunately, the outspoken Lavoisier eventually lost his head in the Terror, but others would follow his lead, carefully examining, measuring, and recording their findings.As the field slowly progressed, another pioneer was to emerged almost 100 years later. Dimitri Mendeleev, an eccentric genius who cut his flowing hair and beard but once a year, sought to answer the most pressing questions that remained to chemists: Why did some elements have properties that resembled those of others? Were there certain natural groups of elements? And, if so, how many, and what elements fit into them? It was Mendeleev who finally addressed all these issues when he constructed the first Periodic Table in the late 1800s.But between and after Lavoisier and Mendeleev were a host of other colorful, brilliant scientists who made their mark on the field of chemistry. Depicting the lively careers of these scientists and their contributions while carefully deconstructing the history and the science, author Richard Morris skillfully brings it all to life. Hailed by Kirkus Reviews as a clear and lively writer with a penchant for down-to-earth examples Morris's gift for explanation ? and pure entertainment ? is abundantly obvious. Taking a cue from the great chemists themselves, Morris has brewed up a potent combination of the alluringly obscure and the historically momentous, spiked with just the right dose of quirky and ribald detail to deliver a magical brew of history, science, and personalities.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Serotonin is the "contentment" neurotransmitter that tells our brains we don't need any more; yet its deficiency leads to depression. Ideally, both are in optimal supply. Yet dopamine evolved to overwhelm serotonin--because our ancestors were more likely to survive if they were constantly motivated--with the result that constant desire can chemically destroy our ability to feel happiness, while sending us down the slippery slope to addiction. In the last forty years, government legislation and subsidies have promoted ever-available temptation (sugar, drugs, social media, porn) combined with constant stress (work, home, money, Internet), with the end result of an unprecedented epidemic of addiction, anxiety, depression, and chronic disease. And with the advent of neuromarketing, corporate America has successfully imprisoned us in an endless loop of desire and consumption from which there is no obvious escape.With his customary wit and incisiveness, Lustig not only reveals the science that drives these states of mind, he points his finger directly at the corporations that helped create this mess, and the government actors who facilitated it, and he offers solutions we can all use in the pursuit of happiness, even in the face of overwhelming opposition. Always fearless and provocative, Lustig marshals a call to action, with seminal implications for our health, our well-being, and our culture.

    And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

    Geological Survey, a lively and revealing history of the world's most disruptive natural disasters, their impact on our culture, and new ways of thinking about the ones to comeNatural disasters emerge from the same forces that give our planet life. Earthquakes have provided us with natural springs. Volcanoes have given us fertile soil. A world without floods would be a world without rain. It is only when these forces exceed our ability to withstand them that they become disasters. Together, these colossal events have shaped our cities and their architecture; elevated leaders and toppled governments; influenced the way we reason, feel, fight, unite, and pray. The history of natural disasters is a history of ourselves.The Big Ones is a look at some of the most devastating disasters in human history, whose reverberations we continue to feel today. It considers Pompeii, and how a volcanic eruption in the first century AD challenged and reinforced prevailing views of religion for centuries to come. It explores the California floods of 1862, examining the failures of our collective memory. And it transports us to today, showing what Hurricane Katrina and the 2004 Indian Ocean tsunami can tell us about governance and globalization. With global temperatures rising, natural disasters are striking with greater frequency. More than just history, The Big Ones is a call to action. Natural disasters are inevitable; human catastrophes are not. With this energizing and richly researched book, Jones offers a look at our past, readying us to face down the Big Ones in our future.

    He looks at the difficult dialogue between science and religion; the conflict between our human desire for permanence and the impermanence of nature; the possibility that our universe is simply an accident; the manner in which modern technology has separated us from direct experience of the world; and our resistance to the view that our bodies and minds can be explained by scientific logic and laws. And behind all of these considerations is the suggestion—at once haunting and exhilarating—that what we see and understand of the world is only a tiny piece of the extraordinary, perhaps unfathomable whole.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    But for those of us who left math behind in high school, the numbers and figures hurled at us as we go about our days can sometimes leave us scratching our heads and feeling as if we’re fumbling through a mathematical minefield. In this eye-opening and extraordinarily accessible book, mathemati­cian Kit Yates illuminates hidden principles that can help us understand and navigate the chaotic and often opaque surfaces of our world. In The Math of Life and Death, Yates takes us on a fascinating tour of everyday situations and grand-scale applications of mathematical concepts, including exponential growth and decay, optimization, statistics and probability, and number systems. Along the way he reveals the mathematical undersides of controversies over DNA testing, medical screening results, and historical events such as the Chernobyl disaster and the Amanda Knox trial. Readers will finish this book with an enlightened perspective on the news, the law, medicine, and history, and will be better equipped to make personal decisions and solve problems with math in mind, whether it’s choosing the shortest checkout line at the grocery store or halting the spread of a deadly disease.

    It's an occasionally ribald, frequently witty and unerringly erudite guided tour of the secret labyrinth that lurks beneath the English language, taking in monks and monkeys, film buffs and buffaloes, and explaining precisely what the Rolling Stones have to do with gardening.

    The discovery of radium in the late 19th century prompted a flurry of experiments to scope the limits of its potential applications. Half Lives tells the fascinating, curious, sometimes macabre story of the element through its ascendance as a desirable item – a present for a queen, a prize in a treasure hunt, a glow-in-the-dark dance costume, a boon to the housewife, and an ingredient in a startling host of consumer products – to its role as a cure-all in everyday 20th-century life.Finally, it details the gradual downfall and discredit of the radium industry through the eyes of the people who bought, sold and eventually came to fear it.Half Lives is an enjoyable journey into the odd areas where science and consumerism meet, telling the tale of the entrepreneurs and consumers in radium’s history who have until now been considered quacks, or fools, or both.

    She draws from her own experiences of illness and bodily injury to engage in an exploration that extends far beyond her life, spanning wide-ranging territory—from poverty tourism to phantom diseases, street violence to reality television, illness to incarceration—in its search for a kind of sight shaped by humility and grace.

    It accommodates four of our five senses, encases the brain, and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and connects our inner selves to the outer world. Yet there is a dark side to the head’s preeminence, one that has, in the course of human history, manifested itself in everything from decapitation to headhunting. So explains anthropologist Frances Larson in this fascinating history of decapitated human heads. From the Western collectors whose demand for shrunken heads spurred massacres to Second World War soldiers who sent the remains of the Japanese home to their girlfriends, from Madame Tussaud modeling the guillotined head of Robespierre to Damien Hirst photographing decapitated heads in city morgues,from grave-robbing phrenologists to skull-obsessed scientists, Larson explores our macabre fixation with severed heads.

    When the seventh row of the periodic table of elements was completed in June 2016 with the addition of four final elements—nihonium, moscovium, tennessine, and oganesson—we at last could identify all the ingredients necessary to construct our world.In Elemental, chemist and science educator Tim James provides an informative, entertaining, and quirkily illustrated guide to the table that shows clearly how this abstract and seemingly jumbled graphic is relevant to our day-to-day lives.James tells the story of the periodic table from its ancient Greek roots, when you could count the number of elements humans were aware of on one hand, to the modern alchemists of the twentieth and twenty-first centuries who have used nuclear chemistry and physics to generate new elements and complete the periodic table. In addition to this, he answers questions such as: What is the chemical symbol for a human? What would happen if all of the elements were mixed together? Which liquid can teleport through walls? Why is the medieval dream of transmuting lead into gold now a reality?Whether you're studying the periodic table for the first time or are simply interested in the fundamental building blocks of the universe—from the core of the sun to the networks in your brain—Elemental is the perfect guide.

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    It can also mean the humbler tools of everyday cooking and eating: a wooden spoon and a skillet, chopsticks and forks.Since prehistory, humans have braved sharp knives, fire, and grindstones to transform raw ingredients into something delicious - or at least edible. Tools shape what we eat, but they have also transformed how we consume, and how we think about, our food. Technology in the kitchen does not just mean the Pacojets and sous-vide of the modernist kitchen. It can also mean the humbler tools of everyday cooking and eating: a wooden spoon and a skillet, chopsticks and forks. In Consider the Fork, award-winning food writer Bee Wilson provides a wonderful and witty tour of the evolution of cooking around the world, revealing the hidden history of everyday objects we often take for granted. Knives - perhaps our most important gastronomic tool - predate the discovery of fire, whereas the fork endured centuries of ridicule before gaining widespread acceptance; pots and pans have been around for millennia, while plates are a relatively recent invention. Many once-new technologies have become essential elements of any well-stocked kitchen - mortars and pestles, serrated knives, stainless steel pots, refrigerators. Others have proved only passing fancies, or were supplanted by better technologies; one would be hard pressed now to find a water-powered egg whisk, a magnet-operated spit roaster, a cider owl, or a turnspit dog. Although many tools have disappeared from the modern kitchen, they have left us with traditions, tastes, and even physical characteristics that we would never have possessed otherwise. Blending history, science, and anthropology, Wilson reveals how our culinary tools and tricks came to be, and how their influence has shaped modern food culture. The story of how we have tamed fire and ice and wielded whisks, spoons, and graters, all for the sake of putting food in our mouths, Consider the Fork is truly a book to savor.