Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Against all predictions, one of the most-disliked presidential candidates in history had swept the electoral college, elevating a man with open contempt for democratic norms and institutions to the height of power.Timothy Snyder is one of the most celebrated historians of the Holocaust. In his books Bloodlands and Black Earth, he has carefully dissected the events and values that enabled the rise of Hitler and Stalin and the execution of their catastrophic policies. With Twenty Lessons, Snyder draws from the darkest hours of the twentieth century to provide hope for the twenty-first. As he writes, “Americans are no wiser than the Europeans who saw democracy yield to fascism, Nazism and communism. Our one advantage is that we might learn from their experience.”Twenty Lessons is a call to arms and a guide to resistance, with invaluable ideas for how we can preserve our freedoms in the uncertain years to come.

    They never saw her again. Her abduction was one of the most notorious episodes of the vicious conflict known as The Troubles. Everyone in the neighborhood knew the I.R.A. was responsible. But in a climate of fear and paranoia, no one would speak of it. In 2003, five years after an accord brought an uneasy peace to Northern Ireland, a set of human bones was discovered on a beach. McConville's children knew it was their mother when they were told a blue safety pin was attached to the dress--with so many kids, she had always kept it handy for diapers or ripped clothes.Patrick Radden Keefe's mesmerizing book on the bitter conflict in Northern Ireland and its aftermath uses the McConville case as a starting point for the tale of a society wracked by a violent guerrilla war, a war whose consequences have never been reckoned with. The brutal violence seared not only people like the McConville children, but also I.R.A. members embittered by a peace that fell far short of the goal of a united Ireland, and left them wondering whether the killings they committed were not justified acts of war, but simple murders.Patrick Radden Keefe writes an intricate narrative about a notorious killing in Northern Ireland and its devastating repercussions.

    Most of the time this math works quietly behind the scenes . . . until it doesn't. All sorts of seemingly innocuous mathematical mistakes can have significant consequences.Math is easy to ignore until a misplaced decimal point upends the stock market, a unit conversion error causes a plane to crash, or someone divides by zero and stalls a battleship in the middle of the ocean.Exploring and explaining a litany of glitches, near misses, and mathematical mishaps involving the internet, big data, elections, street signs, lotteries, the Roman Empire, and an Olympic team, Matt Parker uncovers the bizarre ways math trips us up, and what this reveals about its essential place in our world. Getting it wrong has never been more fun.

    In prose that is, at once, both clear-eyed and full of acerbic wit, Sanghera shows how our past is everywhere: from how we live to how we think, from the foundation of the NHS to the nature of our racism, from our distrust of intellectuals in public life to the exceptionalism that imbued the campaign for Brexit and the government's early response to the Covid crisis. And yet empire is a subject, weirdly hidden from view.The British Empire ran for centuries and covered vast swathes of the world. It is, as Sanghera reveals, fundamental to understanding Britain. However, even among those who celebrate the empire there seems to be a desire not to look at it too closely - not to include the subject in our school history books, not to emphasize it too much in our favourite museums.At a time of great division, when we are arguing about what it means to be British, Sanghera's book urges us to address this bewildering contradiction. For, it is only by stepping back and seeing where we really come from, that we can begin to understand who we are, and what unites us.

    By posing the question, "What does the loss of any one life mean to the rest of the nation?" Lowery examines the cumulative effect of decades of racially biased policing in segregated neighborhoods with failing schools, crumbling infrastructure and too few jobs.Studded with moments of joy, and tragedy, They Can't Kill Us All offers a historically informed look at the standoff between the police and those they are sworn to protect, showing that civil unrest is just one tool of resistance in the broader struggle for justice. As Lowery brings vividly to life, the protests against police killings are also about the black community's long history on the receiving end of perceived and actual acts of injustice and discrimination. They Can't Kill Us All grapples with a persistent if also largely unexamined aspect of the otherwise transformative presidency of Barack Obama: the failure to deliver tangible security and opportunity to those Americans most in need of both. They Can't Kill Us All is a galvanizing book that offers more than just behind-the-scenes coverage of the story of citizen resistance to police brutality. It will also explain where the movement came from, where it is headed and where it still has to go.

    Refashioning the story of human evolution in a work that is certain to generate headlines, Wilson draws on his remarkable knowledge of biology and social behavior to show that group selection, not kin selection, is the primary driving force of human evolution. He proves that history makes no sense without prehistory, and prehistory makes no sense without biology. Demonstrating that the sources of morality, religion, and the creative arts are fundamentally biological in nature, Wilson presents us with the clearest explanation ever produced as to the origin of the human condition and why it resulted in our domination of the Earth’s biosphere.

    Delving into brand-new research, she uncovers the powers of the natural world to improve health, promote reflection and innovation, and strengthen our relationships. As our modern lives shift dramatically indoors, these ideas—and the answers they yield—are more urgent than ever.

    The poverty she grew up in was all-encompassing, grinding and often dehumanising. Always on the move with her single mother, Kerry attended nine primary schools and five secondaries, living in B&Bs and council flats. She scores eight out of ten on the Adverse Childhood Experiences measure of childhood trauma. Twenty years later, Kerry’s life is unrecognisable. She’s a prizewinning novelist who has travelled the world. She has a secure home, a loving partner and access to art, music, film and books. But she often finds herself looking over her shoulder, caught somehow between two worlds.Lowborn is Kerry’s exploration of where she came from, revisiting the towns she grew up in to try to discover what being poor really means in Britain today and whether anything has changed. She also journeys into the hardest regions of her own childhood, because sometimes in order to move forwards we first have to look back.

    Through the stories of victims, perpetrators, law enforcement, and reform movements from across the country, Snyder explores not only the dark corners of private violence, but also its far-reaching consequences for society, and what it will take to truly address it.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Kendi's concept of antiracism reenergizes and reshapes the conversation about racial justice in America--but even more fundamentally, points us toward liberating new ways of thinking about ourselves and each other. In How to be an Antiracist, Kendi asks us to think about what an antiracist society might look like, and how we can play an active role in building it. In this book, Kendi weaves together an electrifying combination of ethics, history, law, and science, bringing it all together with an engaging personal narrative of his own awakening to antiracism. How to Be an Antiracist is an essential work for anyone who wants to go beyond an awareness of racism to the next step: contributing to the formation of a truly just and equitable society.

    Drawing on new genetic and genealogical research, original records, expert testimony and contemporary interviews, Black and British reaches back to Roman Britain, the medieval imagination and Shakespeare's Othello.It reveals that behind the South Sea Bubble was Britain's global slave-trading empire and that much of the great industrial boom of the nineteenth century was built on American slavery. It shows that Black Britons fought at Trafalgar and in the trenches of the First World War. Black British history can be read in stately homes, street names, statues and memorials across Britain and is woven into the cultural and economic histories of the nation.