The Epigenetics Revolution


Nessa Carey - 2011
    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

The World As I See It


Albert Einstein - 1934
    Their attitude towards Einstein is like that of Mark Twain towards the writer of a work on mathematics: here was a man who had written an entire book of which Mark could not understand a single sentence. Einstein, therefore, is great in the public eye partly because he has made revolutionary discoveries which cannot be translated into the common tongue. We stand in proper awe of a man whose thoughts move on heights far beyond our range, whose achievements can be measured only by the few who are able to follow his reasoning and challenge his conclusions. There is, however, another side to his personality. It is revealed in the addresses, letters, and occasional writings brought together in this book. These fragments form a mosaic portrait of Einstein the man. Each one is, in a sense, complete in itself; it presents his views on some aspect of progress, education, peace, war, liberty, or other problems of universal...

Cosmos


Carl Sagan - 1980
    In the book, Sagan explores 15 billion years of cosmic evolution and the development of science and civilization. Cosmos traces the origins of knowledge and the scientific method, mixing science and philosophy, and speculates to the future of science. The book also discusses the underlying premises of science by providing biographical anecdotes about many prominent scientists throughout history, placing their contributions into the broader context of the development of modern science.The book covers a broad range of topics, comprising Sagan's reflections on anthropological, cosmological, biological, historical, and astronomical matters from antiquity to contemporary times. Sagan reiterates his position on extraterrestrial life—that the magnitude of the universe permits the existence of thousands of alien civilizations, but no credible evidence exists to demonstrate that such life has ever visited earth.

The Goldilocks Enigma: Why is the Universe Just Right for Life?


Paul C.W. Davies - 2006
    Here he tackles all the "big questions," including the biggest of them all: Why does the universe seem so well adapted for life? In his characteristically clear and elegant style, Davies shows how recent scientific discoveries point to a perplexing fact: many different aspects of the cosmos, from the properties of the humble carbon atom to the speed of light, seem tailor-made to produce life. A radical new theory says it's because our universe is just one of an infinite number of universes, each one slightly different. Our universe is bio-friendly by accident -- we just happened to win the cosmic jackpot. While this "multiverse" theory is compelling, it has bizarre implications, such as the existence of infinite copies of each of us and Matrix-like simulated universes. And it still leaves a lot unexplained. Davies believes there's a more satisfying solution to the problem of existence: the observations we make today could help shape the nature of reality in the remote past. If this is true, then life -- and, ultimately, consciousness -- aren't just incidental byproducts of nature, but central players in the evolution of the universe. Whether he's elucidating dark matter or dark energy, M-theory or the multiverse, Davies brings the leading edge of science into sharp focus, provoking us to think about the cosmos and our place within it in new and thrilling ways.

Emergence: The Connected Lives of Ants, Brains, Cities, and Software


Steven Johnson - 2001
    Explaining why the whole is sometimes smarter than the sum of its parts, Johnson presents surprising examples of feedback, self-organization, and adaptive learning. How does a lively neighborhood evolve out of a disconnected group of shopkeepers, bartenders, and real estate developers? How does a media event take on a life of its own? How will new software programs create an intelligent World Wide Web? In the coming years, the power of self-organization -- coupled with the connective technology of the Internet -- will usher in a revolution every bit as significant as the introduction of electricity. Provocative and engaging, Emergence puts you on the front lines of this exciting upheaval in science and thought.

Blueprint: The Evolutionary Origins of a Good Society


Nicholas A. Christakis - 2019
    But natural selection has given us a suite of beneficial social features, including our capacity for love, friendship, cooperation, and learning. Beneath all of our inventions -- our tools, farms, machines, cities, nations -- we carry with us innate proclivities to make a good society.In Blueprint, Nicholas A. Christakis introduces the compelling idea that our genes affect not only our bodies and behaviors, but also the ways in which we make societies, ones that are surprisingly similar worldwide.With many vivid examples -- including diverse historical and contemporary cultures, communities formed in the wake of shipwrecks, commune dwellers seeking utopia, online groups thrown together by design or involving artificially intelligent bots, and even the tender and complex social arrangements of elephants and dolphins that so resemble our own -- Christakis shows that, despite a human history replete with violence, we cannot escape our social blueprint for goodness.In a world of increasing political and economic polarization, it's tempting to ignore the positive role of our evolutionary past. But by exploring the ancient roots of goodness in civilization, Blueprint shows that our genes have shaped societies for our welfare and that, in a feedback loop stretching back many thousands of years, societies are still shaping our genes today.

Blueprint: How DNA makes us who we are


Robert Plomin - 2018
    Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences.In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility.A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

The Trouble with Physics: The Rise of String Theory, the Fall of a Science and What Comes Next


Lee Smolin - 2006
    For more than two centuries, our understanding of the laws of nature expanded rapidly. But today, despite our best efforts, we know nothing more about these laws than we knew in the 1970s. Why is physics suddenly in trouble? And what can we do about it?One of the major problems, according to Smolin, is string theory: an ambitious attempt to formulate a “theory of everything” that explains all the particles and forces of nature and how the universe came to be. With its exotic new particles and parallel universes, string theory has captured the public’s imagination and seduced many physicists.But as Smolin reveals, there’s a deep flaw in the theory: no part of it has been tested, and no one knows how to test it. In fact, the theory appears to come in an infinite number of versions, meaning that no experiment will ever be able to prove it false. As a scientific theory, it fails. And because it has soaked up the lion’s share of funding, attracted some of the best minds, and effectively penalized young physicists for pursuing other avenues, it is dragging the rest of physics down with it.With clarity, passion, and authority, Smolin charts the rise and fall of string theory and takes a fascinating look at what will replace it. A group of young theorists has begun to develop exciting ideas that, unlike string theory, are testable. Smolin not only tells us who and what to watch for in the coming years, he offers novel solutions for seeking out and nurturing the best new talent—giving us a chance, at long last, of finding the next Einstein.

What Is Life?: How Chemistry Becomes Biology


Addy Pross - 2012
    So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.

A World Beyond Physics: The Emergence and Evolution of Life


Stuart A. Kauffman - 2019
    Among the estimated one hundred billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of becoming in each case. Since Newton, we have turned to physics to assess reality. Butphysics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.Building on concepts from his work as a complex systems researcher at the Santa Fe Institute, Kauffman focuses in particular on the idea of cells constructing themselves and introduces concepts such as constraint closure. Living systems are defined by the concept of organization which has notbeen focused on in enough in previous works. Cells are autopoetic systems that build themselves: they literally construct their own constraints on the release of energy into a few degrees of freedom that constitutes the very thermodynamic work by which they build their own self creating constraints.Living cells are machines that construct and assemble their own working parts. The emergence of such systems-the origin of life problem-was probably a spontaneous phase transition to self-reproduction in complex enough prebiotic systems. The resulting protocells were capable of Darwin's heritablevariation, hence open-ended evolution by natural selection. Evolution propagates this burgeoning organization. Evolving living creatures, by existing, create new niches into which yet further new creatures can emerge. If life is abundant in the universe, this self-constructing, propagating, exploding diversity takes us beyond physics to biospheres everywhere.

The Feynman Lectures on Physics


Richard P. Feynman - 1964
    A new foreword by Kip Thorne, the current Richard Feynman Professor of Theoretical Physics at Caltech, discusses the relevance of the new edition to today's readers. This boxed set also includes Feynman's new Tips on Physics—the four previously unpublished lectures that Feynman gave to students preparing for exams at the end of his course. Thus, this 4-volume set is the complete and definitive edition of The Feynman Lectures on Physics. Packaged in a specially designed slipcase, this 4-volume set provides the ultimate legacy of Feynman's extraordinary contribution to students, teachers, researches, and lay readers around the world.

Cybernetics: or the Control and Communication in the Animal and the Machine


Norbert Wiener - 1948
    It is a ‘ must’ book for those in every branch of science . . . in addition, economists, politicians, statesmen, and businessmen cannot afford to overlook cybernetics and its tremendous, even terrifying implications. "It is a beautifully written book, lucid, direct, and despite its complexity, as readable by the layman as the trained scientist." -- John B. Thurston, "The Saturday Review of Literature" Acclaimed one of the "seminal books . . . comparable in ultimate importance to . . . Galileo or Malthus or Rousseau or Mill," "Cybernetics" was judged by twenty-seven historians, economists, educators, and philosophers to be one of those books published during the "past four decades", which may have a substantial impact on public thought and action in the years ahead." -- Saturday Review

Life's Edge: The Search for What It Means to Be Alive


Carl Zimmer - 2021
    Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can't answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society's most charged conflicts--whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

The Science Book: Big Ideas Simply Explained


Rob Scott Colson - 2014
     The Science Book covers every area of science--astronomy, biology, chemistry, geology, math, and physics, and brings the greatest scientific ideas to life with fascinating text, quirky graphics, and pithy quotes.

Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies


Geoffrey B. West - 2017
    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.