Warnings that depressive disorder is a leading cause of worldwide disability have been accompanied by a massive upsurge in the consumption of antidepressant medication, widespread screening for depression in clinics and schools, and a push to diagnose depression early, on the basis of just a few symptoms, in order to prevent more severe conditions from developing.In The Loss of Sadness, Allan V. Horwitz and Jerome C. Wakefield argue that, while depressive disorder certainly exists and can be a devastating condition warranting medical attention, the apparent epidemic in fact reflects the way the psychiatric profession has understood and reclassified normal human sadness as largely an abnormal experience. With the 1980 publication of the landmark third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), mental health professionals began diagnosing depression based on symptoms—such as depressed mood, loss of appetite, and fatigue—that lasted for at least two weeks. This system is fundamentally flawed, the authors maintain, because it fails to take into account the context in which the symptoms occur. They stress the importance of distinguishing between abnormal reactions due to internal dysfunction and normal sadness brought on by external circumstances. Under the current DSM classification system, however, this distinction is impossible to make, so the expected emotional distress caused by upsetting events—for example, the loss of a job or the end of a relationship—could lead to a mistaken diagnosis of depressive disorder. Indeed, it is this very mistake that lies at the root of the presumed epidemic of major depression in our midst.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    His revolutionary new book shows, for the first time, how the amazing process of neuroplastic healing really works. It describes natural, non-invasive avenues into the brain provided by the forms of energy around us—light, sound, vibration, movement—which pass through our senses and our bodies to awaken the brain’s own healing capacities without producing unpleasant side effects. Doidge explores cases where patients alleviated years of chronic pain or recovered from debilitating strokes or accidents; children on the autistic spectrum or with learning disorders normalizing; symptoms of multiple sclerosis, Parkinson’s disease, and cerebral palsy radically improved, and other near-miracle recoveries. And we learn how to vastly reduce the risk of dementia with simple approaches anyone can use. For centuries it was believed that the brain’s complexity prevented recovery from damage or disease. The Brain’s Way of Healing shows that this very sophistication is the source of a unique kind of healing. As he did so lucidly in The Brain That Changes Itself, Doidge uses stories to present cutting-edge science with practical real-world applications, and principles that everyone can apply to improve their brain’s performance and health.

    But what is Prozac—a medication, or a mental steroid? A cure for depression, or a drug that changes personality? Reported to turn shy people into social butterflies and to improve work performance, memory, even dexterity, does Prozac work on character rather than illness? Are you using it "cosmetically," to make people more attractive? More energetic, more socially acceptable? And what does it tell us about the nature of character and the mutability of self?

     Auditory hallucination is one of the most awe-inspiring, terrifying, and ill-understood tricks the human psyche is capable of. Muses, Madmen, and Prophets reevaluates the popular conception of the phenomenon today and through the ages, and reveals the roots of the medical understanding and treatment of it. It probes history, literature, anthropology, psychology, and neurology to explain and demystify the experience of hearing voices, in a fascinating and at times funny quest for understanding. Daniel B. Smith's personal experience with the phenomenon-his father heard voices, and it was the great torment and shame of his father's life-and his discovery that some people learn to live in peace with their voices fuels this contemplative, brilliantly researched, and inspired book. Science has not been able to fully explain the phenomenon of auditory hallucination. It is a condition that has existed perhaps as long as we have-there is evidence of it in literature and even pre-literate oral histories from across all times and cultures. Smith presents the sophisticated and radical argument that a negative side effect of living as we do in this great age of medical science is that we have come to limit this phenomenon to nothing more than a biochemical glitch for which the only proper response is medical, pharmaceutical treatment. This "pathological assumption" can inflict great harm on the people who hear voices by ignoring the meaning and reality of the experience for them. But it also obscures from the rest of us a rich wellspring of knowledge about the essential source of faith and inspiration. As Smith examines the many incidences of people who have famously heard voices throughout history-Moses, Mohammed, Teresa of Avila, Joan of Arc, Rilke, William Blake, Socrates, and others-he considers the experience of auditory hallucination in light of its relationship to the nature of pure faith and as the key to the source of artistic inspiration. At the heart of Smith's exploration into the many extraordinary, strange, sometimes frightening and sometimes almost supernatural aspects of auditory hallucination is his driving personal need to comprehend an experience that, when considered in good faith, is as profound and complex as human consciousness itself.

    She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds.But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time.Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well.In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones.A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

    Instead of being the life of the party, someone with Bipolar II might be too nervous to go to the party at all. And, unlike the Bipolar I sufferer who may attempt suicide in a depressive cycle, the Bipolar II might be incapacitated by guilt over an imaginary crime. In Less than Crazy, health writer and Bipolar II sufferer Karla Dougherty shares her story, presenting the first patient-expert's guide to recognizing and living well with this condition. Covering both adults and children, this accessible, all-in-one resource includes information on diagnosis, conditions that may mimic Bipolar II, and treatments.

    Daniel Mierlak, a psychiatrist for twenty-five years, on a journey to the stranger corners of human experience. Here you’ll meet: Tony, chauffeur to the fabulously rich, who overcomes crippling anxiety only to find himself descend into a homicidal rage following a botched cosmetic procedure. Amanda, hospitalized for mania, who sees a change to her medicine as an assassination attempt, and then stalks her doctor for a year after discharge. James, a schizophrenic hearing voices telling him to kill himself, whose piano playing leads to a shocking secret about his past. Psychiatric treatment is normally a private encounter and often misunderstood. In describing twelve of his most challenging cases, Dr. Mierlak brings you into his sessions, into his patients’ lives, and into the world of psychiatry. Get ready for some surprises.

     Gawande draws on clinical studies, case histories and stories from his own experiences as a doctor and a son to illuminate the subject of mortality relative to modern medical systems. His treatment of the subject covers a broad range of institutions and individuals that shape the lives of the aged and terminally ill. The central thesis of the book is that the experience of the end of life has been problematized and addressed by medical models that place extending life over quality of life and institutional frameworks that place safety and efficiency over the ability for people to have autonomy over the last part of their lives. Gawande is a surgeon at Brigham and Women’s Hospital and a professor at the Harvard Medical School. He is a writer at The New Yorker magazine and author of three New York Times bestselling books.

    

    Daniel J. Siegel presents a groundbreaking new way of thinking about the emergence of the human mind, and the process by which each of us becomes a feeling, thinking, remembering individual. Illuminating how and why neurobiology matters, this book is essential reading for clinicians, educators, researchers, and students interested in human experience and development across the life span.

    Currently, millions of people in the U.S. routinely use these pills. Are these miracle drugs, quickly curing depression? Or is their popularity a sign that we now inappropriately redefine normal life problems as diseases? Are they prescribed too often or too seldom? How do they affect self-images?David Karp approaches these questions from the inside, having suffered from clinical depression for most of his adult life. In this book he explores the relationship between pills and personhood by listening to a group of experts who rarely get the chance to speak on the matter—those who are taking the medications. Their voices, extracted from interviews Karp conducted, color the pages with their experiences and reactions--humor, gratitude, frustration, hope, and puzzlement. Here, the patients themselves articulate their impressions of what drugs do to them and for them. They reflect on difficult issues, such as the process of becoming committed to medication, quandaries about personal authenticity, and relations with family and friends.The stories are honest and vivid, from a distraught teenager who shuns antidepressants while regularly using street drugs to a woman who still yearns for a spiritual solution to depression even after telling intimates "I'm on Prozac and it's saving me." The book provides unflinching portraits of people attempting to make sense of a process far more complex and mysterious than doctors or pharmaceutical companies generally admit.

    All over the world scientists, psychologists, and philosophers are waiting to read Antonio Damasio's new theory of the nature of consciousness and the construction of the self. A renowned and revered scientist and clinician, Damasio has spent decades following amnesiacs down hospital corridors, waiting for comatose patients to awaken, and devising ingenious research using PET scans to piece together the great puzzle of consciousness. In his bestselling Descartes' Error, Damasio revealed the critical importance of emotion in the making of reason. Building on this foundation, he now shows how consciousness is created. Consciousness is the feeling of what happens-our mind noticing the body's reaction to the world and responding to that experience. Without our bodies there can be no consciousness, which is at heart a mechanism for survival that engages body, emotion, and mind in the glorious spiral of human life. A hymn to the possibilities of human existence, a magnificent work of ingenious science, a gorgeously written book, The Feeling of What Happens is already being hailed as a classic.

    Addictions to smartphones, sex, games, social media, gambling, money, but most of all to alcohol and drugs. The words 'addict' and 'addiction' are loaded with baggage. Not just in Australia, but the world over, addicts are considered to be sub-human, if not alien. This book aims to reclaim their dignity. It aims to rescue the word 'addiction' from its kidnappers and restore its humanity. It offers personal accounts from inspirational people who have found themselves in the grips of such addictions, and their amazing stories of survival. At the Ted Noffs Foundation, Matt Noffs and Kieran Palmer spend their lives working with young people who have serious and often debilitating drug addictions. This book shares the tools they use every day. It offers insights into why addiction takes place and why it's a natural part of being human. It journeys across the spectrum of addictive behaviors, from social media to drugs like heroin. It questions the assumptions and begins to debunk the myth that all addiction is identical and predictable. Addiction is something that could affect any of us. This is a book that everyone should read.

    Professor Irving Kirsch knew this as well as anyone. But, as he discovered during his research, there is a problem with what everyone knows about antidepressant drugs. It isn't true.How did antidepressant drugs gain their reputation as a magic bullet for depression? And why has it taken so long for the story to become public? Answering these questions takes us to the point where the lines between clinical research and marketing disappear altogether.Using the Freedom of Information Act, Kirsch accessed clinical trials that were withheld, by drug companies, from the public and from the doctors who prescribe antidepressants. What he found, and what he documents here, promises to bring revolutionary change to the way our society perceives, and consumes, antidepressants.The Emperor's New Drugs exposes what we have failed to see before: depression is not caused by a chemical imbalance in the brain; antidepressants are significantly more dangerous than other forms of treatment and are only marginally more effective than placebos; and, there are other ways to combat depression, treatments that don't only include the empty promise of the antidepressant prescription.This is not a book about alternative medicine and its outlandish claims. This is a book about fantasy and wishful thinking in the heart of clinical medicine, about the seductions of myth, and the final stubbornness of facts.