Contents:The Last InchThe Shark Cage

    The aim remains to provide a reference to the aspects of medical microbiology particularly important for clinical infections and chemotherapy. Geo. F. Brooks (U. of California, San Francisco), Jane

    

    Teaches developers how to build database-driven web applications using two of today's most popular open-source software tools, PHP and MySQL.

    Charged under an obscure blasphemy law in a small New Jersey town in 1919, Vijay Sahni is challenged by a skeptical judge to defend his belief that the certainty of mathematics can be extended to all human knowledge--including religion. Together, the two men discover the power--and the fallibility--of what has long been considered the pinnacle of human certainty, Euclidean geometry.As grandfather and grandson struggle with the question of whether there can ever be absolute certainty in mathematics or life, they are forced to reconsider their fundamental beliefs and choices. Their stories hinge on their explorations of parallel developments in the study of geometry and infinity--and the mathematics throughout is as rigorous and fascinating as the narrative and characters are compelling and complex. Moving and enlightening, A Certain Ambiguity is a story about what it means to face the extent--and the limits--of human knowledge.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Two days later, she got her first glimpse of the famous, terrifying jaws up close and she was instantly hooked; her fascination soon yielded to obsession-and an invitation to return for a full season. But as Casey readied herself for the eight-week stint, she had no way of preparing for what she would find among the dangerous, forgotten islands that have banished every campaign for civilization in the past two hundred years.

    With the sophisticated algorithms in this book, you can write smart programs to access interesting datasets from other web sites, collect data from users of your own applications, and analyze and understand the data once you've found it.Programming Collective Intelligence takes you into the world of machine learning and statistics, and explains how to draw conclusions about user experience, marketing, personal tastes, and human behavior in general -- all from information that you and others collect every day. Each algorithm is described clearly and concisely with code that can immediately be used on your web site, blog, Wiki, or specialized application. This book explains:Collaborative filtering techniques that enable online retailers to recommend products or media Methods of clustering to detect groups of similar items in a large dataset Search engine features -- crawlers, indexers, query engines, and the PageRank algorithm Optimization algorithms that search millions of possible solutions to a problem and choose the best one Bayesian filtering, used in spam filters for classifying documents based on word types and other features Using decision trees not only to make predictions, but to model the way decisions are made Predicting numerical values rather than classifications to build price models Support vector machines to match people in online dating sites Non-negative matrix factorization to find the independent features in a dataset Evolving intelligence for problem solving -- how a computer develops its skill by improving its own code the more it plays a game Each chapter includes exercises for extending the algorithms to make them more powerful. Go beyond simple database-backed applications and put the wealth of Internet data to work for you. "Bravo! I cannot think of a better way for a developer to first learn these algorithms and methods, nor can I think of a better way for me (an old AI dog) to reinvigorate my knowledge of the details."-- Dan Russell, Google "Toby's book does a great job of breaking down the complex subject matter of machine-learning algorithms into practical, easy-to-understand examples that can be directly applied to analysis of social interaction across the Web today. If I had this book two years ago, it would have saved precious time going down some fruitless paths."-- Tim Wolters, CTO, Collective Intellect

    This work represents the views of a mathematician on the analogies between computing machines and the living human brain.

    Today's designers need a comprehensive understanding of applied cryptography.After an introduction to cryptography and data security, the authors explain the main techniques in modern cryptography, with chapters addressing stream ciphers, the Data Encryption Standard (DES) and 3DES, the Advanced Encryption Standard (AES), block ciphers, the RSA cryptosystem, public-key cryptosystems based on the discrete logarithm problem, elliptic-curve cryptography (ECC), digital signatures, hash functions, Message Authentication Codes (MACs), and methods for key establishment, including certificates and public-key infrastructure (PKI). Throughout the book, the authors focus on communicating the essentials and keeping the mathematics to a minimum, and they move quickly from explaining the foundations to describing practical implementations, including recent topics such as lightweight ciphers for RFIDs and mobile devices, and current key-length recommendations.The authors have considerable experience teaching applied cryptography to engineering and computer science students and to professionals, and they make extensive use of examples, problems, and chapter reviews, while the book's website offers slides, projects and links to further resources. This is a suitable textbook for graduate and advanced undergraduate courses and also for self-study by engineers.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    10 illustrations.

    Many scientists have traced his upsurge to changes in the dietary habits of North Americans. The Clear Skin Diet is designed to help those who suffer from acne to understand:What it is Why they have it What it has to do with their eating habits And what they can do to prevent it or lessen its impact Modern research shows: That there is a strong causal connection between certain kinds of foods and acne. That certain fats, such as omega-3 fatty acids, protect against acne, while others, saturated or trans fats, can promote acne by increasing the level of inflammation and oxidative stress in the skin. Culinary herbs like ginger and turmeric are known to dampen acne breakouts. These same dietary stresses also influence the level of the hormones that cause acne. While fruits and vegetables, green tea, soy, fish, berries, and fiber-rich whole foods lessen these androgens, meat and milk promote these acne-related hormones, as do sugar and low-fiber carbohydrates. There also is a strong causal connection between the brain and the skin. When a person experiences anxiety and depression, acne-producing hormones are released, which can lead to poor dietary choices high in saturated fats and sugars. The Clear Skin Diet introduces the acne diet and lifestyle. Dietary requirements for protecting the skin are listed - along with suggested food supplements when they cannot be easily met - and summarized, as well as mind-body medical interventions that can influence acne hormones and lessen their impact. Also included are 50 acne-preventive recipes, along with information on how one can locate the ingredients that are not readily available in most grocery stores.

    Join renowned neuroscientist David Eagleman for a journey into the questions at the mysterious heart of our existence. What is reality? Who are “you”? How do you make decisions? Why does your brain need other people? How is technology poised to change what it means to be human?  In the course of his investigations, Eagleman guides us through the world of extreme sports, criminal justice, facial expressions, genocide, brain surgery, gut feelings, robotics, and the search for immortality.  Strap in for a whistle-stop tour into the inner cosmos. In the infinitely dense tangle of billions of brain cells and their trillions of connections, something emerges that you might not have expected to see in there: you.

    Half of all species could disappear by the end of the century, and scientists now concede that most of America’s endangered animals will survive only if conservationists keep rigging the world around them in their favor. So Mooallem ventures into the field, often taking his daughter with him, to move beyond childlike fascination and make those creatures feel more real. Wild Ones is a tour through our environmental moment and the eccentric cultural history of people and wild animals in America that inflects it—from Thomas Jefferson’s celebrations of early abundance to the turn-of the-last-century origins of the teddy bear to the whale-loving hippies of the 1970s. In America, Wild Ones discovers, wildlife has always inhabited the terrain of our imagination as much as the actual land.The journey is framed by the stories of three modern-day endangered species: the polar bear, victimized by climate change and ogled by tourists outside a remote northern town; the little-known Lange’s metalmark butterfly, foundering on a shred of industrialized land near San Francisco; and the whooping crane as it’s led on a months-long migration by costumed men in ultralight airplanes. The wilderness that Wild Ones navigates is a scrappy, disorderly place where amateur conservationists do grueling, sometimes preposterous-looking work; where a marketer maneuvers to control the polar bear’s image while Martha Stewart turns up to film those beasts for her show on the Hallmark Channel. Our most comforting ideas about nature unravel. In their place, Mooallem forges a new and affirming vision of the human animal and the wild ones as kindred creatures on an imperfect planet.With propulsive curiosity and searing wit, and without the easy moralizing and nature worship of environmental journalism’s older guard, Wild Ones merges reportage, science, and history into a humane and endearing meditation on what it means to live in, and bring a life into, a broken world.