But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    His job no longer existed. "I think they just want to hire younger people," his boss at Newsweek told him. Fifty years old and with a wife and two young kids, Dan was, in a word, screwed. Then an idea hit. Dan had long reported on Silicon Valley and the tech explosion. Why not join it? HubSpot, a Boston start-up, was flush with $100 million in venture capital. They offered Dan a pile of stock options for the vague role of "marketing fellow." What could go wrong? HubSpotters were true believers: They were making the world a better place ... by selling email spam. The office vibe was frat house meets cult compound: The party began at four thirty on Friday and lasted well into the night; "shower pods" became hook-up dens; a push-up club met at noon in the lobby, while nearby, in the "content factory," Nerf gun fights raged. Groups went on "walking meetings," and Dan's absentee boss sent cryptic emails about employees who had "graduated" (read: been fired). In the middle of all this was Dan, exactly twice the age of the average HubSpot employee, and literally old enough to be the father of most of his co-workers, sitting at his desk on his bouncy-ball "chair."Mixed in with Lyons's uproarious tale of his rise and fall at Hubspot is a trenchant analysis of the start-up world, a de facto conspiracy between those who start companies and those who fund them, a world where bad ideas are rewarded with hefty investments, where companies blow money lavishing perks on their post-collegiate workforces, and where everybody is trying to hang on just long enough to reach an IPO and cash out. With a cast of characters that includes devilish angel investors, fad-chasing venture capitalists, entrepreneurs and "wantrapreneurs," bloggers and brogrammers, social climbers and sociopaths, Disrupted is a gripping and definitive account of life in the (second) tech bubble.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    The average young person in the UK will spend 10,000 hours gaming by the age of twenty-one. What's causing this mass exodus? According to world-renowned game designer Jane McGonigal the answer is simple: videogames are fulfilling genuine human needs. Drawing on positive psychology, cognitive science and sociology, Reality is Broken shows how game designers have hit on core truths about what makes us happy, and utilized these discoveries to astonishing effect in virtual environments. But why, McGonigal asks, should we use the power of games for escapist entertainment alone? In this groundbreaking exploration of the power and future of gaming, she reveals how gamers have become expert problem solvers and collaborators, and shows how we can use the lessons of game design to socially positive ends, be it in our own lives, our communities or our businesses. Written for gamers and non-gamers alike, Reality is Broken sends a clear and provocative message: the future will belong to those who can understand, design and play games.

    Everything Is Miscellaneous: The Power of the New Digital Disorder

     NAMED ONE OF THE TEN BEST BOOKS OF THE YEAR BY CHICAGO TRIBUNE AND THE DALLAS MORNING NEWS - "A deft blend of nostalgia, humor and devastating insights."--PeopleRemember all those ingrained habits, cherished ideas, beloved objects, and stubborn preferences from the pre-Internet age? They're gone.To some of those things we can say good riddance. But many we miss terribly. Whatever our emotional response to this departed realm, we are faced with the fact that nearly every aspect of modern life now takes place in filtered, isolated corners of cyberspace--a space that has slowly subsumed our physical habitats, replacing or transforming the office, our local library, a favorite bar, the movie theater, and the coffee shop where people met one another's gaze from across the room. Even as we've gained the ability to gather without leaving our house, many of the fundamentally human experiences that have sustained us have disappeared.In one hundred glimpses of that pre-Internet world, Pamela Paul, editor of The New York Times Book Review, presents a captivating record, enlivened with illustrations, of the world before cyberspace--from voicemails to blind dates to punctuation to civility. There are the small losses: postcards, the blessings of an adolescence largely spared of documentation, the Rolodex, and the genuine surprises at high school reunions. But there are larger repercussions, too: weaker memories, the inability to entertain oneself, and the utter demolition of privacy.100 Things We've Lost to the Internet is at once an evocative swan song for a disappearing era and, perhaps, a guide to reclaiming just a little bit more of the world IRL.

    The squalid and turbulent prisons of London were overflowing, and crime was on the rise. Even the hulks sifting at anchor in the Thames were packed with malcontent criminals and petty thieves. So the English government decided to undertake the unprecedented move of shipping off its convicts to a largely unexplored landmass at the other end of the world.Using the personal journals and documents that were kept during this expedition, historian/novelist Thomas Keneally re-creates the grueling overseas voyage, a hellish, suffocating journey that claimed the lives of many convicts. Miraculously, the fleet reached the shores of what was then called New South Wales in 1788, and after much trial and error, the crew managed to set up a rudimentary yet vibrant settlement. As governor of the colony, Phillip took on the challenges of dealing with unruly convicts, disgruntled officers, a bewildered, sometimes hostile native population, as well as such serious matters as food shortages and disease. Moving beyond Phillip, Keneally offers captivating portrayals of Aborigines, who both aided and opposed Phillip, and of the settlers, including convicts who were determined to overcome their pasts and begin anew.With the authority of a renowned historian and the narrative grace of a brilliant novelist, Thomas Keneally offers an insider’s perspective into the dramatic saga of the birth of a vibrant society in an unfamiliar land. A Commonwealth of Thieves immerses us in the fledgling penal colony and conjures up colorful scenes of the joy and heartbreak, the thrills and hardships that characterized those first four improbable years. The result is a lively and engrossing work of history, as well as a tale of redemption for the thousands of convicts who started new lives thousands of miles from their homes.

    Why do we recognize patterns? Is there such a thing as positive stress? Are we genetically programmed to be in conflict with each other? Those are just some of the 150 questions that the world's best scientific minds answer with elegant simplicity.With contributions from Jared Diamond, Richard Dawkins, Nassim Taleb, Brian Eno, Steven Pinker, and more, everything is explained in fun, uncomplicated terms that make the most complex concepts easy to comprehend.

    Chocolate was consumed unrefined and unprocessed as a rather bitter, fatty drink for the wealthy elite until the late 19th century, when the Swiss discovered a way to blend it with milk and unleashed a product that would conquer every market in the world. Thereafter, one of the great global business rivalries unfolded as each chocolate maker attempted to dominate its domestic market and innovate new recipes for chocolate that would set it apart from its rivals. The contest was full of dramatic contradictions: The Cadburys were austere Quakers who found themselves making millions from an indulgent product; Kitty Hershey could hardly have been more flamboyant yet her husband was moved by the Cadburys tradition of philanthropy. Each was a product of their unique time and place yet they shared one thing: they want to make the best chocolate in the world.

    In Empires of Light, historian Jill Jonnes portrays this extraordinary trio and their riveting and ruthless world of cutting-edge science, invention, intrigue, money, death, and hard-eyed Wall Street millionaires. At the heart of the story are Thomas Alva Edison, the nation’s most famous and folksy inventor, creator of the incandescent light bulb and mastermind of the world’s first direct current electrical light networks; the Serbian wizard of invention Nikola Tesla, elegant, highly eccentric, a dreamer who revolutionized the generation and delivery of electricity; and the charismatic George Westinghouse, Pittsburgh inventor and tough corporate entrepreneur, an industrial idealist who in the era of gaslight imagined a world powered by cheap and plentiful electricity and worked heart and soul to create it. Edison struggled to introduce his radical new direct current (DC) technology into the hurly-burly of New York City as Tesla and Westinghouse challenged his dominance with their alternating current (AC), thus setting the stage for one of the eeriest feuds in American corporate history, the War of the Electric Currents. The battlegrounds: Wall Street, the 1893 Chicago World’s Fair, Niagara Falls, and, finally, the death chamber - Jonnes takes us on the tense walk down a prison hallway and into the sunlit room where William Kemmler, convicted ax murderer, became the first man to die in the electric chair. Empires of Light is the gripping history of electricity, the “mysterious fluid,” and how the fateful collision of Edison, Tesla, and Westinghouse left the world utterly transformed.

    There are many positive ways in which the Internet has contributed to the world, but as a society we are less aware of the Internet’s deeply negative effects on our psychology, economy, and culture. In The Internet Is Not the Answer, Andrew Keen, a twenty-year veteran of the tech industry, traces the technological and economic history of the internet from its founding in the 1960s through the rise of the big data companies to the increasing attempts to monetize almost every human activity, and investigates how the internet is reconfiguring our world—often at great cost. In this sharp, witty narrative, informed by the work of other writers, academics, and reporters, as well as his own wide-ranging research and interviews, Keen shows us the tech world, warts and all, and investigates what we can do to make sure the choices we make about the reconfiguring of our society do not lead to unpleasant unforeseen aftershocks.

    Wells to the press releases of NASA, we are awash in clich�d claims about high technology's ability to change the course of history. Now, in The Shock of the Old, David Edgerton offers a startling new and fresh way of thinking about the history of technology, radically revising our ideas about the interaction of technology and society in the past and in the present. He challenges us to view the history of technology in terms of what everyday people have actually used-and continue to use-rather than just sophisticated inventions. Indeed, many highly touted technologies, from the V-2 rocket to the Concorde jet, have been costly failures, while many mundane discoveries, like corrugated iron, become hugely important around the world. Edgerton reassesses the significance of such acclaimed inventions as the Pill and information technology, and underscores the continued importance of unheralded technology, debunking many notions about the implications of the information age. A provocative history, The Shock of the Old provides an entirely new way of looking historically at the relationship between invention and innovation.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    The story of Fox News' ascent is an epic story of political power, business success, brass-knuckle tactics, and old-school showmanship.

    . . or at least he wasn’t until these books came along. Made up of intensively edited speeches and interviews, they offer something not found anywhere else: pure Chomsky, with every dazzling idea and penetrating insight intact, delivered in clear, accessible, reader-friendly prose.Published as four short books in the famous Real Story series—What Uncle Sam Really Wants; The Prosperous Few and the Restless Many; Secrets, Lies and Democracy; and The Common Good—they’ve collectively sold almost 600,000 copies.And they continue to sell year after year after year because Chomsky’s ideas become, if anything, more relevant as time goes by. For example, twenty years ago he pointed out that “in 1970, about 90% of international capital was used for trade and long-term investment—more or less productive things—and 10% for speculation. By 1990, those figures had reversed.” As we know, speculation continued to increase exponentially. We’re paying the price now for not heeding him them.