As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    But Malcolm X, the most famous minister in the Nation of Islam-a sect many white Americans deemed a hate cult-saw the potential in Clay, not just for boxing greatness, but as a means of spreading the Nation's message. The two became fast friends, keeping their interactions secret from the press for fear of jeopardizing Clay's career. Clay began living a double life-a patriotic "good Negro" in public, and a radical reformer behind the scenes. Soon, however, their friendship would sour, with disastrous and far-reaching consequences.Based on previously untapped sources, from Malcolm's personal papers to FBI records, Blood Brothers is the first book to offer an in-depth portrait of this complex bond. Acclaimed historians Randy Roberts and Johnny Smith reconstruct the worlds that shaped Malcolm and Clay, from the boxing arenas and mosques, to postwar New York and civil rights-era Miami. In an impressively detailed account, they reveal how Malcolm molded Cassius Clay into Muhammad Ali, helping him become an international symbol of black pride and black independence. Yet when Malcolm was barred from the Nation for criticizing the philandering of its leader, Elijah Muhammad, Ali turned his back on Malcolm-a choice that tragically contributed to the latter's assassination in February 1965.Malcolm's death marked the end of a critical phase of the civil rights movement, but the legacy of his friendship with Ali has endured. We inhabit a new era where the roles of entertainer and activist, of sports and politics, are more entwined than ever before. Blood Brothers is the story of how Ali redefined what it means to be a black athlete in America-after Malcolm first enlightened him. An extraordinary narrative of love and deep affection, as well as deceit, betrayal, and violence, this story is a window into the public and private lives of two of our greatest national icons, and the tumultuous period in American history that they helped to shape.

    I didn't know that if a girl broke your heart, another girl, virtuous at least in spirit, could mend it on the same night. And I didn't know that the enthalpy decrease in a converging passage could be transformed into jet kinetic energy if a divergent passage was added. The other boys discovered their own truths when we built our rockets, but those were mine."So begins Homer "Sonny" Hickam Jr.'s extraordinary memoir of life in Coalwood, West Virginia - a hard-scrabble little mining company town where the only things that mattered were coal mining and high school football and where the future was regarded with more fear than hope. Looking back after a distinguished NASA career, Hickam shares the story of his youth, taking readers into the life of the little mining town of Coalwood and the boys who would come to embody its dreams. In 1957 a young man watched the Soviet satellite Sputnik shoot across the Appalachian sky and soon found his future in the stars. 'Sonny' and a handful of his friends, Roy Lee Cook, Sherman O'Dell and Quentin Wilson were inspired to start designing and launching the home-made rockets that would change their lives forever.Step by step, with the help (and occasional hindrance) of a collection of unforgettable characters, the boys learn not only how to turn scrap into sophisticated rockets that fly miles into the sky, but how to sustain their dreams as they dared to imagine a life beyond its borders in a town that the postwar boom was passing by.A powerful story of growing up and of getting out, of a mother's love and a father's fears, Homer Hickam's memoir Rocket Boys proves, like Angela's Ashes and Russell Baker's Growing Up before it, that the right storyteller and the right story can touch readers' hearts and enchant their souls.A uniquely endearing book with universal themes of class, family, coming of age, and the thrill of discovery, Homer Hickam's Rocket Boys is evocative, vivid storytelling at its most magical.In 1999, Rocket Boys was made into a Hollywood movie named October Sky starring Chris Cooper, Jake Gyllenhaal and Laura Dern. October Sky is an anagram of Rocket Boys. It is also used in a period radio broadcast describing Sputnik 1 as it crossed the 'October sky'. Homer Hickam stated that "Universal Studios marketing people got involved and they just had to change the title because, according to their research, women over thirty would never see a movie titled Rocket Boys" so Universal Pictures changed the title to be more inviting to a wider audience. The book was later re-released with the name October Sky in order to capitalize on interest in the movie.

    Determined to finally bite the bullet and saddle up, she set off for Argentina, home of the nomadic gaucho whose spirit still gallops across the plains. In this sprawling country, six-year-olds travel to school on horseback. How difficult could it be? As she learns to sit astride a horse without falling off and befriends the marvelous creatures around her, Polly leaps into the sights and sounds of Argentina past and present: a hair-raising mystery involving Evita Perón becomes a parable about women, politics, and religion; a tango performance in Buenos Aires an occasion for both sorrow and rejoicing. From wine tasting in the Andes to exploring the legendary Perito Moreno Glacier, from investigating the myth of the gaucho to discovering her Welsh roots in Patagonia, Polly takes us along for an exhilarating, unforgettable ride as she finally lives out her dream—at a trot, a canter, and a gallop.

     Thoughtful, inspiring, and often surprising, AND THE GOOD NEWS IS . . . traces Dana Perino's unlikely journey through politics and television. It's a remarkable American story-made up of equal parts determination and clear-eyed optimism. From facing professional challenges and confronting personal fears to stepping up to a podium for a President, Dana has come to expect the unexpected and has an uncanny ability to find the good news in any tough situation. AND THE GOOD NEWS IS . . . takes us from her Western childhood in Wyoming and Colorado to a chance meeting on an airplane that changes her life entirely. Then, with refreshing honesty and humor, she recounts her frustration with a string of unsatisfying jobs and living circumstances until a key career tip leads her back to Washington, D.C. to work for the Bush Administration. Dana also shares here her best work and life lessons-tips that will help you to get your point across convincingly while allowing your own grace and personality to shine through. As someone who still believes in working together to solve the problems our nation faces, Dana offers clear, practical advice on how to restore civility to our personal and public conversations. The result is a fascinating read that can help anyone become more successful, productive, and joyously content.

    Carole King, Joni Mitchell, and Carly Simon remain among the most enduring and important women in popular music. Each woman is distinct. Carole King is the product of outer-borough, middle-class New York City; Joni Mitchell is a granddaughter of Canadian farmers; and Carly Simon is a child of the Manhattan intellectual upper crust. They collectively represent, in their lives and their songs, a great swath of American girls who came of age in the late 1960s. Their stories trace the arc of the now mythic sixties generation -- female version -- but in a bracingly specific and deeply recalled way, far from cliche. The history of the women of that generation has never been written -- until now, through their resonant lives and emblematic songs. Filled with the voices of many dozens of these women's intimates, who are speaking in these pages for the first time, this alternating biography reads like a novel -- except it's all true, and the heroines are famous and beloved. Sheila Weller captures the character of each woman and gives a balanced portrayal enriched by a wealth of new information. Girls Like Us is an epic treatment of mid-century women who dared to break tradition and become what none had been before them -- confessors in song, rock superstars, and adventurers of heart and soul.

    When Theodore Roosevelt became president in 1901, his beautiful and flamboyant daughter was transformed into "Princess Alice," arguably the century's first global celebrity. Thirty-two years later, her first cousin Eleanor moved into the White House as First Lady. Born eight months and twenty blocks apart from each other in New York City, Eleanor and Alice spent a large part of their childhoods together and were far more alike than most historians acknowledge. But their politics and temperaments couldn't have been more distinct. Do-gooder Eleanor was committed to social justice but hated the limelight; acid-tongued Alice, who became the wife of philandering Republican congressman Nicholas Longworth, was an opponent of big government who gained notoriety for her cutting remarks (she famously quipped that dour President Coolidge “looked like he was weaned on a pickle”). While Eleanor revolutionized the role of First Lady with her outspoken passion for human rights, Alice made the most of her insider connections to influence politics, including doing as much to defeat the League of Nations as anyone in elective office.The cousins themselves liked to play up their oil-and-water relationship. “When I think of Frank and Eleanor in the White House I could grind my teeth to powder and blow them out my nose,” Alice once said. In the 1930s they even wrote opposing syndicated newspaper columns and embarked on competing nationwide speaking tours. Blood may be thicker than water, but when the family business is politics, winning trumps everything.Vivid, intimate, and stylishly written, Hissing Cousins finally sets this relationship center stage, revealing the contentious bond between two political trailblazers who short-circuited the rules of gender and power, each in her own way.

    Discover why this friendship was so crucial to Roosevelt's development as a man and a president-and why it still matters today.

    We see the visionary, whose desire for escape honed an innate sense of what people wanted to see on the screen and, when combined with iron determination and obsessive perfectionism, led him to the reinvention of animation. It was Disney, first with Mickey Mouse and then with his feature films - most notably Snow White, Pinocchio, Fantasia, Dumbo, and Bambi - who transformed animation from a novelty based on movement to an art form that presented an illusion of life.We see him reimagine the amusement park with Disneyland, prompting critics to coin the word Disneyfication to describe the process by which reality can be modified to fit one's personal desires. At the same time, he provided a new way to connect with American history through his live-action films and purveyed a view of the country so coherent that even today one can speak meaningfully of "Walt Disney's America." We see how the True-Life Adventure nature documentaries he produced helped create the environmental movement by sensitizing the general public to issues of conservation. And we see how he reshaped the entertainment industry by building a synergistic empire that combined film, television, theme parks, music, book publishing, and merchandise in a way that was unprecedented and was later widely imitated.Gabler also reveals a wounded, lonely, and often disappointed man, who, despite worldwide success, was plagued with financial problems much of his life, suffered a nervous breakdown, and at times retreated into pitiable seclusion in his workshop making model trains. Gabler explores accusations that Disney was a red-baiter, an anti-Semite, an embittered alcoholic. But whatever the characterizations of Disney's personal life, he appealed to the nation by demonstrating the power of wish fulfillment and the triumph of the American imagination. Walt Disney showed how one could impose one's will on the world.This is a masterly biography, a revelation of both the work and the man - of both the remarkable accomplishment and the hidden life.

    When she was fourteen years old, Maud wrote in her journal, "I love books. I hope when I grow up to be able to have lots of them." Not only did Maud grow up to own lots of books, she wrote twenty-four of them herself as L. M. Montgomery, the world-renowned author of Anne of Green Gables. For many years, not a great deal was known about Maud’s personal life. Her childhood was spent with strict, undemonstrative grandparents, and her reflections on writing, her lifelong struggles with anxiety and depression, her "year of mad passion," and her difficult married life remained locked away, buried deep within her unpublished personal journals. Through this revealing and deeply moving biography, kindred spirits of all ages who, like Maud, never gave up "the substance of things hoped for" will be captivated anew by the words of this remarkable woman.

    But when he impulsively auditioned for a school production of West Side Story, he found his purpose—or so it seemed. Within a few years Gary and a handful of friends created what became one of the most exciting and important new theater companies in America. From its humble beginnings in a suburban Chicago church basement and eventual move into the city, the Steppenwolf Theatre Company launched a series of groundbreaking productions, igniting Gary's career along with those of John Malkovich, Joan Allen, Gary Cole, Laurie Metcalf, Jeff Perry, John Mahoney, and others. Television and film came calling soon after, and Gary starred in Of Mice and Men (which he also directed) and The Stand before taking the role that would change his life in unforeseeable ways: Lieutenant Dan in the Academy Award–winning Forrest Gump.The military community's embrace of the character of the disabled veteran was matched only by the depth of Gary's realization that America's defenders had not received all the honor, respect, and gratitude their sacrifices deserve. In the aftermath of the September 11 attacks, this became Gary's mission. While starring in hits like Apollo 13, Ransom, Truman, George Wallace, CSI:NY, and Criminal Minds: Beyond Borders, Gary has worked tirelessly on behalf of those who serve this country, entertaining more than a half million troops around the world playing bass guitar with his Lt. Dan Band, raising funds on behalf of veterans, and eventually founding the Gary Sinise Foundation with a mission to serve and honor America's defenders, veterans, first responders, their families, and those in need.Grateful American is the moving, entertaining, profoundly gripping story of how one man found his calling: to see that those who defend this country and its freedoms are never forgotten.

    To that incontrovertible end, John Entwistle-the Who's beloved bassist-remains an enigmatic yet undeniably influential figure, renowned as much for his immense talent as for his gloriously oversized-seeming character. However, unlike his fellow musicians, Entwistle has yet to be the subject of a major biography. In the years since his death, his enduring legacy has been carefully guarded by his loved ones, preventing potential biographers from gaining close enough access to write a definitive account of his extraordinary life-until now. For the first time, and with the full co-operation of the Entwistle family, The Ox shines a long overdue light on one of the most important figures in rock history. Drawing on his own notes for an unfinished autobiography that he started before his death in 2002, as well as his personal archives and interviews with his family and friends, The Ox gives readers a never-before-seen glimpse into the two very distinct poles of John Entwistle. On the one hand, he was the rock star incarnate-larger than life, self-obsessed to a fault, and proudly and almost defiantly so. Extravagant with money, he famously shipped vintage American cars across the Atlantic without having so much as a driver's license, built exponentially bigger and grandiose bars into every home he owned, and amassed an extraordinary collection of possessions, from armor and weaponry to his patented Cuban-heel boots. But beneath this fame and flutter, he was also a man of simple tastes and traditional opinions. He was a devoted father and family man who loved nothing more than to wake up to a full English breakfast, or to have a supper of fish, chips, and a pint at his local pub. After his untimely death, many of these stories were shuttered away into the memories of his family and friends. At long last, The Ox introduces us to the man behind the myth-the iconic and inimitable John Entwistle.

    In 1774, at the age of seventeen, Georgiana achieved immediate celebrity by marrying one of England's richest and most influential aristocrats, the Duke of Devonshire. Launched into a world of wealth and power, she quickly became the queen of fashionable society, adored by the Prince of Wales, a dear friend of Marie-Antoinette, and leader of the most important salon of her time. Not content with the role of society hostess, she used her connections to enter politics, eventually becoming more influential than most of the men who held office. Her good works and social exploits made her loved by the multitudes, but Georgiana's public success, like Diana's, concealed a personal life that was fraught with suffering. The Duke of Devonshire was unimpressed by his wife's legendary charms, preferring instead those of her closest friend, a woman with whom Georgiana herself was rumored to be on intimate terms. For over twenty years, the three lived together in a jealous and uneasy ménage à trois, during which time both women bore the Duke's children—as well as those of other men.Foreman's descriptions of Georgiana's uncontrollable gambling, all-night drinking, drug taking, and love affairs with the leading politicians of the day give us fascinating insight into the lives of the British aristocracy in the era of the madness of King George III, the American and French revolutions, and the defeat of Napoleon. A gifted young historian whom critics are already likening to Antonia Fraser, Amanda Foreman draws on a wealth of fresh research and writes colorfully and penetratingly about the fascinating Georgiana, whose struggle against her own weaknesses, whose great beauty and flamboyance, and whose determination to play a part in the affairs of the world make her a vibrant, astonishingly contemporary figure.

    In the wake of her mother’s death, her family scattered and her own marriage was soon destroyed. Four years later, with nothing more to lose, she made the most impulsive decision of her life. With no experience or training, driven only by blind will, she would hike more than a thousand miles of the Pacific Crest Trail from the Mojave Desert through California and Oregon to Washington State — and she would do it alone.Told with suspense and style, sparkling with warmth and humor, Wild powerfully captures the terrors and pleasures of one young woman forging ahead against all odds on a journey that maddened, strengthened, and ultimately healed her.

    She was the rarest of female psychopaths, a woman who engaged in wholesale slaughter, partly out of greed but mostly for the sheer joy of it. Between 1902 and 1908, she lured a succession of unsuspecting victims to her Indiana “murder farm.” Some were hired hands. Others were well-to-do bachelors. All of them vanished without a trace. When their bodies were dug up, they hadn’t merely been poisoned, like victims of other female killers. They’d been butchered.Hell’s Princess is a riveting account of one of the most sensational killing sprees in the annals of American crime: the shocking series of murders committed by the woman who came to be known as Lady Bluebeard. The only definitive book on this notorious case and the first to reveal previously unknown information about its subject, Harold Schechter’s gripping, suspenseful narrative has all the elements of a classic mystery—and all the gruesome twists of a nightmare.