Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    But what if you could have your computer do them for you?In "Automate the Boring Stuff with Python," you'll learn how to use Python to write programs that do in minutes what would take you hours to do by hand no prior programming experience required. Once you've mastered the basics of programming, you'll create Python programs that effortlessly perform useful and impressive feats of automation to: Search for text in a file or across multiple filesCreate, update, move, and rename files and foldersSearch the Web and download online contentUpdate and format data in Excel spreadsheets of any sizeSplit, merge, watermark, and encrypt PDFsSend reminder emails and text notificationsFill out online formsStep-by-step instructions walk you through each program, and practice projects at the end of each chapter challenge you to improve those programs and use your newfound skills to automate similar tasks.Don't spend your time doing work a well-trained monkey could do. Even if you've never written a line of code, you can make your computer do the grunt work. Learn how in "Automate the Boring Stuff with Python.""

    

    It's used worldwide by companies who need to produce reliable, efficient, and scalable applications. Invest in learning Erlang now.Moore's Law is the observation that the amount you can do on a single chip doubles every two years. But Moore's Law is taking a detour. Rather than producing faster and faster processors, companies such as Intel and AMD are producing multi-core devices: single chips containing two, four, or more processors. If your programs aren't concurrent, they'll only run on a single processor at a time. Your users will think that your code is slow.Erlang is a programming language designed for building highly parallel, distributed, fault-tolerant systems. It has been used commercially for many years to build massive fault-tolerated systems that run for years with minimal failures.Erlang programs run seamlessly on multi-core computers: this means your Erlang program should run a lot faster on a 4 core processor than on a single core processor, all without you having to change a line of code.Erlang combines ideas from the world of functional programming with techniques for building fault-tolerant systems to make a powerful language for building the massively parallel, networked applications of the future.This book presents Erlang and functional programming in the familiar Pragmatic style. And it's written by Joe Armstrong, one of the creators of Erlang.It includes example code you'll be able to build upon. In addition, the book contains the full source code for two interesting applications:A SHOUTcast server which you can use to stream music to every computer in your house, and a full-text indexing and search engine that can index gigabytes of data. Learn how to write programs that run on dozens or even hundreds of local and remote processors. See how to write robust applications that run even in the face of network and hardware failure, using the Erlang programming language.

    But, Alex Bellos says, "math can be inspiring and brilliantly creative. Mathematical thought is one of the great achievements of the human race, and arguably the foundation of all human progress. The world of mathematics is a remarkable place."Bellos has traveled all around the globe and has plunged into history to uncover fascinating stories of mathematical achievement, from the breakthroughs of Euclid, the greatest mathematician of all time, to the creations of the Zen master of origami, one of the hottest areas of mathematical work today. Taking us into the wilds of the Amazon, he tells the story of a tribe there who can count only to five and reports on the latest findings about the math instinct--including the revelation that ants can actually count how many steps they've taken. Journeying to the Bay of Bengal, he interviews a Hindu sage about the brilliant mathematical insights of the Buddha, while in Japan he visits the godfather of Sudoku and introduces the brainteasing delights of mathematical games.Exploring the mysteries of randomness, he explains why it is impossible for our iPods to truly randomly select songs. In probing the many intrigues of that most beloved of numbers, pi, he visits with two brothers so obsessed with the elusive number that they built a supercomputer in their Manhattan apartment to study it. Throughout, the journey is enhanced with a wealth of intriguing illustrations, such as of the clever puzzles known as tangrams and the crochet creation of an American math professor who suddenly realized one day that she could knit a representation of higher dimensional space that no one had been able to visualize. Whether writing about how algebra solved Swedish traffic problems, visiting the Mental Calculation World Cup to disclose the secrets of lightning calculation, or exploring the links between pineapples and beautiful teeth, Bellos is a wonderfully engaging guide who never fails to delight even as he edifies. "Here's Looking at Euclid "is a rare gem that brings the beauty of math to life.

    It can also be used by English speakers and is a practical, user-friendly book intended as a fast, do-it-yourself guide for those whose English language proficiency is above intermediate. The approach is based on material developed from teaching graduate students at Imperial College London and has been extensively piloted. The book guides the reader through the process of writing science research and will also help with writing a Master's or Doctoral thesis in English.Science writing is much easier than it looks because the structure and language are conventional. The aim of this book is to help the reader discover a template or model for science research writing and then to provide the grammar and vocabulary tools needed to operate that model. There are five units: Introduction, Methodology, Results, Discussion/Conclusion and Abstract. The reader develops a model for each section of the research article through sample texts and exercises; this is followed by a Grammar and Writing Skills section designed to respond to frequently-asked questions as well as a Vocabulary list including examples of how the words and phrases are to be used.

    He is also the Head Teaching Fellow for the most popular course at Harvard, “Positive Psychology,” which is taken by more than 1,000 students per semester and led by Professor Tal Ben-Shahar.  Shawn received his B.A. in English from Harvard and a Master’s from Harvard Divinity School in Christian and Buddhist Ethics. Part of his interest in positive psychology stems from a troubling fact: studies have shown that many of Harvard’s undergraduates suffer from depression at some point in their college careers. One Day University is a unique educational experience  that brings intellectuals together to learn from top rated professors at Yale, Harvard, Stanford, Columbia and other prestigious universities. Chosen for their excellent teaching abilities as rated by their students, these great thinkers represent a wide variety of academic disciplines and share their knowledge in 60 minute, highly entertaining lectures. Offering the ability to learn the highlights of academic thought in world affairs, politics, history, science, art, and more; One Day University is a way to truly enjoy the thrill of learning without the pressures of tests and the high price tag of college tuition. Once reserved only for students who could attend the lectures in New York and other major cities, One Day University courses are now available to everyone from the comfort of their own homes in Kindle format.

    Written in a frank but engaging style, Debuggingprovides simple, foolproof principles guaranteed to help find any bug quickly. This book makes those shelves of application-specific debugging books (on C++, Perl, Java, etc.) obsolete. It changes the way readers think about debugging, making those pesky problems suddenly much easier to find and fix. Illustrating the rules with real-life bug-detection war stories, the book shows readers how to: * Understand the system: how perceiving the ""roadmap"" can hasten your journey * Quit thinking and look: when hands-on investigation can’t be avoided * Isolate critical factors: why changing one element at a time can be an essential tool * Keep an audit trail: how keeping a record of the debugging process can win the day

    Verification that algorithms work is emphasized more than their complexity. An effective use of examples, and huge number of interesting exercises, demonstrate the topics of trees and distance, matchings and factors, connectivity and paths, graph coloring, edges and cycles, and planar graphs. For those who need to learn to make coherent arguments in the fields of mathematics and computer science.

    Conflict between humans and machines is seen as inevitable and its outcome all too predictable.In this groundbreaking book, distinguished AI researcher Stuart Russell argues that this scenario can be avoided, but only if we rethink AI from the ground up. Russell begins by exploring the idea of intelligence in humans and in machines. He describes the near-term benefits we can expect, from intelligent personal assistants to vastly accelerated scientific research, and outlines the AI breakthroughs that still have to happen before we reach superhuman AI. He also spells out the ways humans are already finding to misuse AI, from lethal autonomous weapons to viral sabotage.If the predicted breakthroughs occur and superhuman AI emerges, we will have created entities far more powerful than ourselves. How can we ensure they never, ever, have power over us? Russell suggests that we can rebuild AI on a new foundation, according to which machines are designed to be inherently uncertain about the human preferences they are required to satisfy. Such machines would be humble, altruistic, and committed to pursue our objectives, not theirs. This new foundation would allow us to create machines that are provably deferential and provably beneficial.In a 2014 editorial co-authored with Stephen Hawking, Russell wrote, "Success in creating AI would be the biggest event in human history. Unfortunately, it might also be the last." Solving the problem of control over AI is not just possible; it is the key that unlocks a future of unlimited promise.

    However, most discussions of Bayesian inference rely on intensely complex mathematical analyses and artificial examples, making it inaccessible to anyone without a strong mathematical background. Now, though, Cameron Davidson-Pilon introduces Bayesian inference from a computational perspective, bridging theory to practice-freeing you to get results using computing power. Bayesian Methods for Hackers illuminates Bayesian inference through probabilistic programming with the powerful PyMC language and the closely related Python tools NumPy, SciPy, and Matplotlib. Using this approach, you can reach effective solutions in small increments, without extensive mathematical intervention. Davidson-Pilon begins by introducing the concepts underlying Bayesian inference, comparing it with other techniques and guiding you through building and training your first Bayesian model. Next, he introduces PyMC through a series of detailed examples and intuitive explanations that have been refined after extensive user feedback. You'll learn how to use the Markov Chain Monte Carlo algorithm, choose appropriate sample sizes and priors, work with loss functions, and apply Bayesian inference in domains ranging from finance to marketing. Once you've mastered these techniques, you'll constantly turn to this guide for the working PyMC code you need to jumpstart future projects. Coverage includes - Learning the Bayesian "state of mind" and its practical implications - Understanding how computers perform Bayesian inference - Using the PyMC Python library to program Bayesian analyses - Building and debugging models with PyMC - Testing your model's "goodness of fit" - Opening the "black box" of the Markov Chain Monte Carlo algorithm to see how and why it works - Leveraging the power of the "Law of Large Numbers" - Mastering key concepts, such as clustering, convergence, autocorrelation, and thinning - Using loss functions to measure an estimate's weaknesses based on your goals and desired outcomes - Selecting appropriate priors and understanding how their influence changes with dataset size - Overcoming the "exploration versus exploitation" dilemma: deciding when "pretty good" is good enough - Using Bayesian inference to improve A/B testing - Solving data science problems when only small amounts of data are available Cameron Davidson-Pilon has worked in many areas of applied mathematics, from the evolutionary dynamics of genes and diseases to stochastic modeling of financial prices. His contributions to the open source community include lifelines, an implementation of survival analysis in Python. Educated at the University of Waterloo and at the Independent University of Moscow, he currently works with the online commerce leader Shopify.

    Intended for developers who are already familiar with the Apex language, and experienced Java and C# developers who are moving to Apex, this book starts where the Force.com documentation leaves off. Instead of trying to cover all of the features of the platform, Advanced Apex programming focuses entirely on the Apex language and core design patterns. You’ll learn how to truly think in Apex – to embrace limits and bulk patterns. You’ll see how to develop architectures for efficient and reliable trigger handling, and for asynchronous operations. You’ll discover that best practices differ radically depending on whether you are building software for a specific organization or for a managed package. And you’ll find approaches for incorporating testing and diagnostic code that can dramatically improve the reliability and deployment of Apex software, and reduce your lifecycle and support costs. Based on his experience both as a consultant and as architect of a major AppExchange package, Dan Appleman focuses on the real-world problems and issues that are faced by Apex developers every day, along with the obscure problems and surprises that can sneak up on you if you are unprepared.

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    This book is an insider's guide to these little understood topics.Author Jeremy Zawodny has managed large numbers of MySQL servers for mission-critical work at Yahoo!, maintained years of contacts with the MySQL AB team, and presents regularly at conferences. Jeremy and Derek have spent months experimenting, interviewing major users of MySQL, talking to MySQL AB, benchmarking, and writing some of their own tools in order to produce the information in this book.In "High Performance MySQL" you will learn about MySQL indexing and optimization in depth so you can make better use of these key features. You will learn practical replication, backup, and load-balancing strategies with information that goes beyond available tools to discuss their effects in real-life environments. And you'll learn the supporting techniques you need to carry out these tasks, including advanced configuration, benchmarking, and investigating logs.Topics include: A review of configuration and setup optionsStorage engines and table typesBenchmarkingIndexesQuery OptimizationApplication DesignServer PerformanceReplicationLoad-balancingBackup and RecoverySecurity

    He solidified his standing as the nation's foremost political forecaster with his near perfect prediction of the 2012 election. Silver is the founder and editor in chief of FiveThirtyEight.com. Drawing on his own groundbreaking work, Silver examines the world of prediction, investigating how we can distinguish a true signal from a universe of noisy data. Most predictions fail, often at great cost to society, because most of us have a poor understanding of probability and uncertainty. Both experts and laypeople mistake more confident predictions for more accurate ones. But overconfidence is often the reason for failure. If our appreciation of uncertainty improves, our predictions can get better too. This is the "prediction paradox": The more humility we have about our ability to make predictions, the more successful we can be in planning for the future.In keeping with his own aim to seek truth from data, Silver visits the most successful forecasters in a range of areas, from hurricanes to baseball, from the poker table to the stock market, from Capitol Hill to the NBA. He explains and evaluates how these forecasters think and what bonds they share. What lies behind their success? Are they good-or just lucky? What patterns have they unraveled? And are their forecasts really right? He explores unanticipated commonalities and exposes unexpected juxtapositions. And sometimes, it is not so much how good a prediction is in an absolute sense that matters but how good it is relative to the competition. In other cases, prediction is still a very rudimentary-and dangerous-science.Silver observes that the most accurate forecasters tend to have a superior command of probability, and they tend to be both humble and hardworking. They distinguish the predictable from the unpredictable, and they notice a thousand little details that lead them closer to the truth. Because of their appreciation of probability, they can distinguish the signal from the noise.